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The map label for this gene is nadX

Identifier: 15669105

GI number: 15669105

Start: 846703

End: 847506

Strand: Reverse

Name: nadX

Synonym: MJ0915

Alternate gene names: 15669105

Gene position: 847506-846703 (Counterclockwise)

Preceding gene: 15669106

Following gene: 15669104

Centisome position: 50.9

GC content: 33.46

Gene sequence:

>804_bases
ATGCTTAAAATTGGTATTGTTGGTTGTGGAGCTATTGGCAATTTTATAACAAAAAAAGTTTTAGATGGAACTATAAAAAA
TGCCAAAATCTCCGCTGTCTATGATAGAAATTTTGACAAGGCAAAAACACTTTCAGAAAGAACTGGGGCTAAGATATGTA
GTAGTATTGATGATTTAGTTAAAGAAGATTTAGATTTAGTTGTTGAGGCAGCTTCAATAAAGGCAGTTGAAGAGATTGCA
GAAAAATCTTTAATAAATAATAAGGATGTTTTAATAATGAGTGTTGGTGCATTGGCAGATAAAAAGCTGTTTTTAAAACT
TAGAGATTTAGCTAAAACTGTTGGAAGAAAGATTTATCTGCCCTCTGGAGCTATTGGTGGCTTAGATGCCATAAAAGCTC
TGAGATTGGGAGAGATAGAGGAGGTTGTTTTAAAAACTACAAAACCAGTTGCTGCCTTAGAGGATGCGTTGAAAAACCTT
GGTTATAAACCAGAAGATATAAAAAATCCAGTAATTGTTTTTGAAGGGGATGTTTTTAAAGCTATAAAAGAATTTCCAGC
AAATATAAATGTTTCAGTTACTTTATCGATAGCCGCAGAGTTTCCAGCAAAGGTTGTTATTGTTGCAGACCCAAATGCTA
AATTGAACAAACATGAACTATTTGTTAAAAGCTCTATAGGAACATTGAGAGTTTGTATTGAAAATGTTCCATTTGAAGAA
AATCCAAGAACCTCTGCATTGGCTGCCTATTCAGCTGTTAGGTTGATTAGAGATTTAGCTGAGCCAGTAAAAGTTGGAAC
TTAA

Upstream 100 bases:

>100_bases
AATAAAAAAACAATAATATATTCTGTCTTTTATAATAAATTAGGCTTATTATTTATTTTTCTAAAAAATTTTATTTTATT
GTTTTTAGGAGGGATAACTA

Downstream 100 bases:

>100_bases
AAGCTTTAATTCGTGGAGAATATGGAAGAGATAGAAAAATTTACAGTTATTGATTTGGATAGCTTAGATAATTTTATAAA
AGTAGTTAGATGTCCAAACT

Product: L-aspartate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLKIGIVGCGAIGNFITKKVLDGTIKNAKISAVYDRNFDKAKTLSERTGAKICSSIDDLVKEDLDLVVEAASIKAVEEIA
EKSLINNKDVLIMSVGALADKKLFLKLRDLAKTVGRKIYLPSGAIGGLDAIKALRLGEIEEVVLKTTKPVAALEDALKNL
GYKPEDIKNPVIVFEGDVFKAIKEFPANINVSVTLSIAAEFPAKVVIVADPNAKLNKHELFVKSSIGTLRVCIENVPFEE
NPRTSALAAYSAVRLIRDLAEPVKVGT

Sequences:

>Translated_267_residues
MLKIGIVGCGAIGNFITKKVLDGTIKNAKISAVYDRNFDKAKTLSERTGAKICSSIDDLVKEDLDLVVEAASIKAVEEIA
EKSLINNKDVLIMSVGALADKKLFLKLRDLAKTVGRKIYLPSGAIGGLDAIKALRLGEIEEVVLKTTKPVAALEDALKNL
GYKPEDIKNPVIVFEGDVFKAIKEFPANINVSVTLSIAAEFPAKVVIVADPNAKLNKHELFVKSSIGTLRVCIENVPFEE
NPRTSALAAYSAVRLIRDLAEPVKVGT
>Mature_267_residues
MLKIGIVGCGAIGNFITKKVLDGTIKNAKISAVYDRNFDKAKTLSERTGAKICSSIDDLVKEDLDLVVEAASIKAVEEIA
EKSLINNKDVLIMSVGALADKKLFLKLRDLAKTVGRKIYLPSGAIGGLDAIKALRLGEIEEVVLKTTKPVAALEDALKNL
GYKPEDIKNPVIVFEGDVFKAIKEFPANINVSVTLSIAAEFPAKVVIVADPNAKLNKHELFVKSSIGTLRVCIENVPFEE
NPRTSALAAYSAVRLIRDLAEPVKVGT

Specific function: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate

COG id: COG1712

COG function: function code R; Predicted dinucleotide-utilizing enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L-aspartate dehydrogenase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASPD_METJA (Q58325)

Other databases:

- EMBL:   L77117
- PIR:   C64414
- RefSeq:   NP_247910.1
- ProteinModelPortal:   Q58325
- SMR:   Q58325
- GeneID:   1451804
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0915
- NMPDR:   fig|243232.1.peg.947
- TIGR:   MJ0915
- HOGENOM:   HBG649642
- OMA:   ECAGHSA
- ProtClustDB:   PRK13304
- BioCyc:   MJAN243232:MJ_0915-MONOMER
- BRENDA:   1.4.1.21
- HAMAP:   MF_01265
- InterPro:   IPR005106
- InterPro:   IPR002811
- InterPro:   IPR011182
- InterPro:   IPR020626
- InterPro:   IPR022487
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF005227
- TIGRFAMs:   TIGR03855

Pfam domain/function: PF01958 DUF108; PF03447 NAD_binding_3

EC number: =1.4.1.21

Molecular weight: Translated: 28755; Mature: 28755

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: ACT_SITE 218-218 BINDING 124-124 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIGIVGCGAIGNFITKKVLDGTIKNAKISAVYDRNFDKAKTLSERTGAKICSSIDDLV
CEEEEEEECCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
KEDLDLVVEAASIKAVEEIAEKSLINNKDVLIMSVGALADKKLFLKLRDLAKTVGRKIYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCEEEE
PSGAIGGLDAIKALRLGEIEEVVLKTTKPVAALEDALKNLGYKPEDIKNPVIVFEGDVFK
CCCCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHCCCEEEEECHHHH
AIKEFPANINVSVTLSIAAEFPAKVVIVADPNAKLNKHELFVKSSIGTLRVCIENVPFEE
HHHHCCCCCEEEEEEEEEECCCEEEEEEECCCCCCCHHHEEEECCCCHHHHHHHCCCCCC
NPRTSALAAYSAVRLIRDLAEPVKVGT
CCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKIGIVGCGAIGNFITKKVLDGTIKNAKISAVYDRNFDKAKTLSERTGAKICSSIDDLV
CEEEEEEECCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
KEDLDLVVEAASIKAVEEIAEKSLINNKDVLIMSVGALADKKLFLKLRDLAKTVGRKIYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCEEEE
PSGAIGGLDAIKALRLGEIEEVVLKTTKPVAALEDALKNLGYKPEDIKNPVIVFEGDVFK
CCCCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHCCCEEEEECHHHH
AIKEFPANINVSVTLSIAAEFPAKVVIVADPNAKLNKHELFVKSSIGTLRVCIENVPFEE
HHHHCCCCCEEEEEEEEEECCCEEEEEEECCCCCCCHHHEEEECCCCHHHHHHHCCCCCC
NPRTSALAAYSAVRLIRDLAEPVKVGT
CCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087