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The map label for this gene is yleA [C]

Identifier: 15669058

GI number: 15669058

Start: 789986

End: 791269

Strand: Reverse

Name: yleA [C]

Synonym: MJ0867

Alternate gene names: 15669058

Gene position: 791269-789986 (Counterclockwise)

Preceding gene: 15669059

Following gene: 15669055

Centisome position: 47.52

GC content: 32.87

Gene sequence:

>1284_bases
ATGTGGTTATATTATTTACAAGTGGTGATGGATATGAGAGTATATGTTGAGGGCTATGGATGCGTTTTAAACACCGCTGA
TACAGAAATTATAAAGAATTCTCTAAAAAAACATGGATTTGAAGTAGTTAATAACTTAGAAGAGGCAGATATTGCAATAA
TAAACACATGTGTTGTTAGATTAGAAACAGAGAATAGAATGATTTACAGAATAAACGAACTTAAAAATTTAGGAAAGGAG
GTTGTTGTTGCTGGATGTTTGCCAAAGGCTTTAAAGAATAAGGTTAAAGGATTCCTACATATATATCCAAGAGAAGCTCA
CAAAGCTGGAGAGATATTGAAAAATTACGTTGAAAAACACTACAGAATGCCATATATTGAAGAGGACATCAACAAAACAC
TCTATAAGAAGTTAGATTACTTAAAACCATCATTAATTACTCCATTGCCAATATGTGAAGGTTGTATAGGAAACTGCAGT
TACTGCATTGTGAAAATAGCAAGAGGTGGGCTAATATCTTATCCAAGAGAAAAAATCGTTAATAAAGCCAAAGAGTTAAT
AAATAAAGGAGCTAAATGCTTGTTGATAACTGCACAAGATACTGCATGCTATGGATTTGATATTGGAGATAACTTAGCTA
ACCTATTGAATGAGCTAACTCAAATAAAGGGAGAGTTTATAATGAGAGTTGGAATGATGCATGCTAAAAATGCTGAACTA
ATCTTAGATGAACTTATAGAAGTCTATCAAAATGAGAAAGTTGGAAAATTTCTACATTTGCCTTTACAAAGTGGAGACGA
TGAGATTTTAAAGAGAATGAAGAGAGGTTATACAGTAGATGAATTTAAAGACATTGTAAATGAATTCAGAAGGAAAATTA
AAAATCTCTGCTTTACAACAGATATAATCGTTGGATTCCCCGGAGAGACAGAGGAGCAGTTTCAAAATACCTTAGAGGTT
TTGAGGGAGTTAAAGCCAGACTATATTCACGGAGCTAAATACTCTCAAAGAAAAGGAACTGAGGCAGCAAAGATGAAGCA
GATAGATACAAAAATTAGAAAGAGAAGAAGTGAAATTTTAGATAAATTGAGGAGGGAGTTGAGCTATCTAAATAACAAAA
AGTATATTGGAAAGGCTATGAAAGTTTTAGTTTTAGATGAGGGAAAAGGTTATACTGACAACTTTAAAGTTGTTAAATTT
GAAGGAGGGGAGGTAGGAGAGTTTAGAAAAGTGAAAATTACTGATGCTAAGACGTTTGGATTGAAAGGGGAGCTTATCCT
TTAA

Upstream 100 bases:

>100_bases
TTTGATTGAGTAAGTTTATAAACTCTAACTTGCTATTGCTATTTTATTTTCTATTTCTTATTTGGTTATTATTAAATAAT
GCACAACATAAAATTTAAAT

Downstream 100 bases:

>100_bases
TTTCCTTTAAAACCTCATCTAAATCAACGTTTTTAACCTCTCCAAATTTAACAACCTCTCCGTCTCCTTCATACCTTGGA
ATGATATGGAAATGAACATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MWLYYLQVVMDMRVYVEGYGCVLNTADTEIIKNSLKKHGFEVVNNLEEADIAIINTCVVRLETENRMIYRINELKNLGKE
VVVAGCLPKALKNKVKGFLHIYPREAHKAGEILKNYVEKHYRMPYIEEDINKTLYKKLDYLKPSLITPLPICEGCIGNCS
YCIVKIARGGLISYPREKIVNKAKELINKGAKCLLITAQDTACYGFDIGDNLANLLNELTQIKGEFIMRVGMMHAKNAEL
ILDELIEVYQNEKVGKFLHLPLQSGDDEILKRMKRGYTVDEFKDIVNEFRRKIKNLCFTTDIIVGFPGETEEQFQNTLEV
LRELKPDYIHGAKYSQRKGTEAAKMKQIDTKIRKRRSEILDKLRRELSYLNNKKYIGKAMKVLVLDEGKGYTDNFKVVKF
EGGEVGEFRKVKITDAKTFGLKGELIL

Sequences:

>Translated_427_residues
MWLYYLQVVMDMRVYVEGYGCVLNTADTEIIKNSLKKHGFEVVNNLEEADIAIINTCVVRLETENRMIYRINELKNLGKE
VVVAGCLPKALKNKVKGFLHIYPREAHKAGEILKNYVEKHYRMPYIEEDINKTLYKKLDYLKPSLITPLPICEGCIGNCS
YCIVKIARGGLISYPREKIVNKAKELINKGAKCLLITAQDTACYGFDIGDNLANLLNELTQIKGEFIMRVGMMHAKNAEL
ILDELIEVYQNEKVGKFLHLPLQSGDDEILKRMKRGYTVDEFKDIVNEFRRKIKNLCFTTDIIVGFPGETEEQFQNTLEV
LRELKPDYIHGAKYSQRKGTEAAKMKQIDTKIRKRRSEILDKLRRELSYLNNKKYIGKAMKVLVLDEGKGYTDNFKVVKF
EGGEVGEFRKVKITDAKTFGLKGELIL
>Mature_427_residues
MWLYYLQVVMDMRVYVEGYGCVLNTADTEIIKNSLKKHGFEVVNNLEEADIAIINTCVVRLETENRMIYRINELKNLGKE
VVVAGCLPKALKNKVKGFLHIYPREAHKAGEILKNYVEKHYRMPYIEEDINKTLYKKLDYLKPSLITPLPICEGCIGNCS
YCIVKIARGGLISYPREKIVNKAKELINKGAKCLLITAQDTACYGFDIGDNLANLLNELTQIKGEFIMRVGMMHAKNAEL
ILDELIEVYQNEKVGKFLHLPLQSGDDEILKRMKRGYTVDEFKDIVNEFRRKIKNLCFTTDIIVGFPGETEEQFQNTLEV
LRELKPDYIHGAKYSQRKGTEAAKMKQIDTKIRKRRSEILDKLRRELSYLNNKKYIGKAMKVLVLDEGKGYTDNFKVVKF
EGGEVGEFRKVKITDAKTFGLKGELIL

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain

Homologues:

Organism=Homo sapiens, GI93277076, Length=384, Percent_Identity=32.5520833333333, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI28872782, Length=481, Percent_Identity=27.2349272349272, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI28872784, Length=481, Percent_Identity=27.2349272349272, Blast_Score=152, Evalue=7e-37,
Organism=Escherichia coli, GI1786882, Length=447, Percent_Identity=28.1879194630872, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1787057, Length=445, Percent_Identity=27.8651685393258, Blast_Score=157, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71996771, Length=293, Percent_Identity=34.8122866894198, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17553146, Length=468, Percent_Identity=28.4188034188034, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19922432, Length=433, Percent_Identity=30.4849884526559, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI21356207, Length=481, Percent_Identity=28.0665280665281, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y867_METJA (Q58277)

Other databases:

- EMBL:   L77117
- PIR:   C64408
- RefSeq:   NP_247862.1
- ProteinModelPortal:   Q58277
- SMR:   Q58277
- GeneID:   1451756
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0867
- NMPDR:   fig|243232.1.peg.899
- TIGR:   MJ0867
- HOGENOM:   HBG457663
- OMA:   GCYGFDI
- ProtClustDB:   CLSK876369
- BioCyc:   MJAN243232:MJ_0867-MONOMER
- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792
- PANTHER:   PTHR11918
- SMART:   SM00729
- TIGRFAMs:   TIGR01578
- TIGRFAMs:   TIGR00089

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004

EC number: NA

Molecular weight: Translated: 49091; Mature: 49091

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS51449 MTTASE_N; PS01278 MTTASE_RADICAL; PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLYYLQVVMDMRVYVEGYGCVLNTADTEIIKNSLKKHGFEVVNNLEEADIAIINTCVVR
CHHHHHHHHHHHHHHEEECCEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEHEEEE
LETENRMIYRINELKNLGKEVVVAGCLPKALKNKVKGFLHIYPREAHKAGEILKNYVEKH
EECCCCEEEEEHHHHHCHHHHHHHHCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHH
YRMPYIEEDINKTLYKKLDYLKPSLITPLPICEGCIGNCSYCIVKIARGGLISYPREKIV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHH
NKAKELINKGAKCLLITAQDTACYGFDIGDNLANLLNELTQIKGEFIMRVGMMHAKNAEL
HHHHHHHHCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ILDELIEVYQNEKVGKFLHLPLQSGDDEILKRMKRGYTVDEFKDIVNEFRRKIKNLCFTT
HHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DIIVGFPGETEEQFQNTLEVLRELKPDYIHGAKYSQRKGTEAAKMKQIDTKIRKRRSEIL
HEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DKLRRELSYLNNKKYIGKAMKVLVLDEGKGYTDNFKVVKFEGGEVGEFRKVKITDAKTFG
HHHHHHHHHHCCHHHHHHHEEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEC
LKGELIL
CCCCEEC
>Mature Secondary Structure
MWLYYLQVVMDMRVYVEGYGCVLNTADTEIIKNSLKKHGFEVVNNLEEADIAIINTCVVR
CHHHHHHHHHHHHHHEEECCEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEHEEEE
LETENRMIYRINELKNLGKEVVVAGCLPKALKNKVKGFLHIYPREAHKAGEILKNYVEKH
EECCCCEEEEEHHHHHCHHHHHHHHCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHH
YRMPYIEEDINKTLYKKLDYLKPSLITPLPICEGCIGNCSYCIVKIARGGLISYPREKIV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHH
NKAKELINKGAKCLLITAQDTACYGFDIGDNLANLLNELTQIKGEFIMRVGMMHAKNAEL
HHHHHHHHCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ILDELIEVYQNEKVGKFLHLPLQSGDDEILKRMKRGYTVDEFKDIVNEFRRKIKNLCFTT
HHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DIIVGFPGETEEQFQNTLEVLRELKPDYIHGAKYSQRKGTEAAKMKQIDTKIRKRRSEIL
HEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DKLRRELSYLNNKKYIGKAMKVLVLDEGKGYTDNFKVVKFEGGEVGEFRKVKITDAKTFG
HHHHHHHHHHCCHHHHHHHEEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEC
LKGELIL
CCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087