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The map label for this gene is idsA

Identifier: 15669051

GI number: 15669051

Start: 782858

End: 783841

Strand: Reverse

Name: idsA

Synonym: MJ0860

Alternate gene names: 15669051

Gene position: 783841-782858 (Counterclockwise)

Preceding gene: 15669052

Following gene: 15669050

Centisome position: 47.08

GC content: 31.2

Gene sequence:

>984_bases
TTGAAAGAATTATTTAAAAGAGGTGGAATTATGCTCTTTGATAAAAATATTTTACAAAAAATTGATGAAGAATTAAAGAC
TTATGTAGATAAAGATGATAAACTATATAACGCGTCAAAACATCTTCTATTTGCTGGAGGAAAGAGAATTAGGCCATATT
TAACTGTAGTAACTTATATGTTGAAGAAAGACGATATTGAGGAGGTTTTGCCAGCCGCTGCTGCAGTAGAGTTAATTCAC
AACTACACCTTAATACATGATGACATTATGGACAATGATGATGAGAGGAGAGGAAAACCAACAGTTCATGTTGTCTATGG
AGAGCCAATGGCTATCTTAGCTGGAGATTTATTATATGCTAAAGCTTTTGAAGCAGTTTCAAGAATAAAAGATAATAAAA
AAGCTCATGAAGTTTTAAAAATCCTATCAAAAGCATGTGTTGAGGTTTGTGAAGGGCAGGCAATGGACATGGAATTTGAA
AACTACTATCCTACAATGGAAGAATACTTAGATATGATTAGAAAAAAGACAGGAGCTTTATTAGAGGCTTCTGTGGGAAT
TGGGGCTGTTATGGCTGATTGTAATGAAGAAGAAAGGGAAGCATTAAAAGAGTATGCAAAAAGAATTGGATTAACTTTTC
AAATACAGGATGATGTTTTAGATTTAATTGGGGACCAGAAAAAGTTAGGTAAGCCAGTTGGAAGTGATATAAGAGAAGGT
AAAAAGACAATAATTGTTATCCACGCCCTAAAAACATTGGATGAAGATAAAAAGAAAAGATTATTGGAAATTTTAGGAAA
TAAAAATGTTAAGGATGAAGAAATTAAAGAAGCAATTGAGATATTAAAGCCTTCAATTGAATATGCAAAAGAACTTATGA
AACAAAAAACTGAAGAAGCAAAAGAATATTTAAAGATATTCAATAAAGACAGAAGGAAAGTTTTAGAGGATTTGGCTGAT
TTTATAATGAGTAGAATTTATTAA

Upstream 100 bases:

>100_bases
GACTTTAACTTAACAGCTGAATATACAAAATTAGCTGAGGAAGAAGGTTATAGATTGGGAGAGGATGTTCATTTATTAAG
AAATGGGCAGTGTTTGAGCT

Downstream 100 bases:

>100_bases
ATTTTATTTGGGGTGAATATTATGAGAATTCCAAGGTTGTATGTTGAAAACGCTGAGAAACATGAGGGAAGAAAGGTAGT
TATTGAAAATGGCGGAAAAG

Product: bifunctional short chain isoprenyl diphosphate synthase IdsA

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKELFKRGGIMLFDKNILQKIDEELKTYVDKDDKLYNASKHLLFAGGKRIRPYLTVVTYMLKKDDIEEVLPAAAAVELIH
NYTLIHDDIMDNDDERRGKPTVHVVYGEPMAILAGDLLYAKAFEAVSRIKDNKKAHEVLKILSKACVEVCEGQAMDMEFE
NYYPTMEEYLDMIRKKTGALLEASVGIGAVMADCNEEEREALKEYAKRIGLTFQIQDDVLDLIGDQKKLGKPVGSDIREG
KKTIIVIHALKTLDEDKKKRLLEILGNKNVKDEEIKEAIEILKPSIEYAKELMKQKTEEAKEYLKIFNKDRRKVLEDLAD
FIMSRIY

Sequences:

>Translated_327_residues
MKELFKRGGIMLFDKNILQKIDEELKTYVDKDDKLYNASKHLLFAGGKRIRPYLTVVTYMLKKDDIEEVLPAAAAVELIH
NYTLIHDDIMDNDDERRGKPTVHVVYGEPMAILAGDLLYAKAFEAVSRIKDNKKAHEVLKILSKACVEVCEGQAMDMEFE
NYYPTMEEYLDMIRKKTGALLEASVGIGAVMADCNEEEREALKEYAKRIGLTFQIQDDVLDLIGDQKKLGKPVGSDIREG
KKTIIVIHALKTLDEDKKKRLLEILGNKNVKDEEIKEAIEILKPSIEYAKELMKQKTEEAKEYLKIFNKDRRKVLEDLAD
FIMSRIY
>Mature_327_residues
MKELFKRGGIMLFDKNILQKIDEELKTYVDKDDKLYNASKHLLFAGGKRIRPYLTVVTYMLKKDDIEEVLPAAAAVELIH
NYTLIHDDIMDNDDERRGKPTVHVVYGEPMAILAGDLLYAKAFEAVSRIKDNKKAHEVLKILSKACVEVCEGQAMDMEFE
NYYPTMEEYLDMIRKKTGALLEASVGIGAVMADCNEEEREALKEYAKRIGLTFQIQDDVLDLIGDQKKLGKPVGSDIREG
KKTIIVIHALKTLDEDKKKRLLEILGNKNVKDEEIKEAIEILKPSIEYAKELMKQKTEEAKEYLKIFNKDRRKVLEDLAD
FIMSRIY

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family

Homologues:

Organism=Homo sapiens, GI4758430, Length=274, Percent_Identity=31.021897810219, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI83700220, Length=274, Percent_Identity=31.021897810219, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI50659086, Length=254, Percent_Identity=28.3464566929134, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1789578, Length=302, Percent_Identity=31.1258278145695, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786623, Length=289, Percent_Identity=35.2941176470588, Blast_Score=134, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17505681, Length=185, Percent_Identity=30.8108108108108, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17508563, Length=296, Percent_Identity=28.0405405405405, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325188, Length=293, Percent_Identity=28.3276450511945, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319475, Length=303, Percent_Identity=26.7326732673267, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24651612, Length=294, Percent_Identity=26.1904761904762, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281365769, Length=290, Percent_Identity=27.5862068965517, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24660002, Length=290, Percent_Identity=27.5862068965517, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17137582, Length=255, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDSA_METJA (Q58270)

Other databases:

- EMBL:   L77117
- PIR:   D64407
- RefSeq:   NP_247855.1
- ProteinModelPortal:   Q58270
- SMR:   Q58270
- GeneID:   1451749
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0860
- NMPDR:   fig|243232.1.peg.892
- TIGR:   MJ0860
- HOGENOM:   HBG732667
- OMA:   TFQIQDD
- ProtClustDB:   CLSK876365
- BioCyc:   MJAN243232:MJ_0860-MONOMER
- BRENDA:   2.5.1.1
- BRENDA:   2.5.1.10
- GO:   GO:0005737
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949
- Gene3D:   G3DSA:1.10.600.10
- PANTHER:   PTHR12001

Pfam domain/function: PF00348 polyprenyl_synt; SSF48576 Terpenoid_synth

EC number: =2.5.1.1; =2.5.1.10

Molecular weight: Translated: 37569; Mature: 37569

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00723 POLYPRENYL_SYNTHASE_1; PS00444 POLYPRENYL_SYNTHASE_2

Important sites: BINDING 48-48 BINDING 51-51 BINDING 80-80 BINDING 96-96 BINDING 97-97 BINDING 176-176 BINDING 177-177 BINDING 214-214 BINDING 231-231 BINDING 241-241

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELFKRGGIMLFDKNILQKIDEELKTYVDKDDKLYNASKHLLFAGGKRIRPYLTVVTYM
CHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCCHHHHCCCHHEEECCCHHHHHHHHHHHH
LKKDDIEEVLPAAAAVELIHNYTLIHDDIMDNDDERRGKPTVHVVYGEPMAILAGDLLYA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
KAFEAVSRIKDNKKAHEVLKILSKACVEVCEGQAMDMEFENYYPTMEEYLDMIRKKTGAL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHCCH
LEASVGIGAVMADCNEEEREALKEYAKRIGLTFQIQDDVLDLIGDQKKLGKPVGSDIREG
HHHHCCHHHHHHCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCHHHHCCCCCHHHHCC
KKTIIVIHALKTLDEDKKKRLLEILGNKNVKDEEIKEAIEILKPSIEYAKELMKQKTEEA
CCEEEEEHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KEYLKIFNKDRRKVLEDLADFIMSRIY
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKELFKRGGIMLFDKNILQKIDEELKTYVDKDDKLYNASKHLLFAGGKRIRPYLTVVTYM
CHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCCHHHHCCCHHEEECCCHHHHHHHHHHHH
LKKDDIEEVLPAAAAVELIHNYTLIHDDIMDNDDERRGKPTVHVVYGEPMAILAGDLLYA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
KAFEAVSRIKDNKKAHEVLKILSKACVEVCEGQAMDMEFENYYPTMEEYLDMIRKKTGAL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHCCH
LEASVGIGAVMADCNEEEREALKEYAKRIGLTFQIQDDVLDLIGDQKKLGKPVGSDIREG
HHHHCCHHHHHHCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCHHHHCCCCCHHHHCC
KKTIIVIHALKTLDEDKKKRLLEILGNKNVKDEEIKEAIEILKPSIEYAKELMKQKTEEA
CCEEEEEHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KEYLKIFNKDRRKVLEDLADFIMSRIY
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087