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The map label for this gene is mptA [H]

Identifier: 15668956

GI number: 15668956

Start: 696431

End: 697381

Strand: Direct

Name: mptA [H]

Synonym: MJ0775

Alternate gene names: 15668956

Gene position: 696431-697381 (Clockwise)

Preceding gene: 15668955

Following gene: 15668957

Centisome position: 41.83

GC content: 34.17

Gene sequence:

>951_bases
GTGAAGATGATGAATTGGAGATGTGATGTTCAAAATTTTGAGCCAGATGTTAAAATATCATTAACAAGAGTTGGAGTTAC
AAATCTAAAAAAACTTGTTAGATTAAAGAGAACAAATAAAAGACCAATAATATTGTTATCTACGTTTGAGGTTTTTGTTA
ATTTGCCGAGTTCTCAGAAAGGAATACACATGTCAAGAAATCCTGAAGTTATAGAGGGAATAATAGATGAGGCTTTAGAG
TTGGAGAGTTATGAGATGGAGACAATTTGTGAGGAGATAGTTAAGAGGTTGTTTGAGAAGCATGAATATGCCACAGAGGC
AGAGGTTTTTATGGTTAGTGATTTCATGACTAAGGAGAAAAGCCCTATATCTGGGAAGTATTCCCAGGAGATTCACAAAA
TCATGGGTGGAGCTAAGGGAATAAAGAAGGATGATGAAATTGAATTAACAAAGATTGTTGGGGCCGAGGTTGTTGGTATC
ACTGCTTGTCCATGTGCTCAAAATTTAATAAAGGAGATATGTATTAAAAACTTAAAGGAAAAAGGCTTTTCTGATGAAGA
TATTGATAAAATATTGGATTCTGTTATATTTGCCACTCATAATCAGAGAGGAATTGGTAGAATTATATTGGAAGTTCCTA
CCGGATATGATATTGAGATTATGGATATCATAGAAATAATTAAAAAATCCATGAGTGCTGAGATTCATGGAATATTAAAG
AGAGCTGATGAAGCTTATGTTGTTGAACAAAGCCATAAAAACCCTAAGTTTGTTGAGGATTGTGTTAGGGAGATGGCTAA
AAGGGTAGTGGAGAAATTTAAACACTTACCAGATGAGACGAAGGTTTTAATTAGGCAGATAAATATGGAGAGTATTCATA
GACATGACGCATTTGCTGAAAAGGTTGCTACATTGGGGGAATTAAGAAGAGAGCTTTTAAGCTATGAATAA

Upstream 100 bases:

>100_bases
CATCTCTCTGACATCTATGAGATGGGATATATTTATAAAGAAAGGGAAGGAAACAACGTATATTATAAACTATCTAAAGA
ACTTAGGGATGTCTTAATAG

Downstream 100 bases:

>100_bases
TTTCACGCTCTTTTTATTTAGCTGTTTATATTTTATAGGTGGTAATTTGAAAGCTTTGGTTTTAGGTATCAACACAAGGC
CTGTAGTTAATTCTCTTAAA

Product: GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKMMNWRCDVQNFEPDVKISLTRVGVTNLKKLVRLKRTNKRPIILLSTFEVFVNLPSSQKGIHMSRNPEVIEGIIDEALE
LESYEMETICEEIVKRLFEKHEYATEAEVFMVSDFMTKEKSPISGKYSQEIHKIMGGAKGIKKDDEIELTKIVGAEVVGI
TACPCAQNLIKEICIKNLKEKGFSDEDIDKILDSVIFATHNQRGIGRIILEVPTGYDIEIMDIIEIIKKSMSAEIHGILK
RADEAYVVEQSHKNPKFVEDCVREMAKRVVEKFKHLPDETKVLIRQINMESIHRHDAFAEKVATLGELRRELLSYE

Sequences:

>Translated_316_residues
MKMMNWRCDVQNFEPDVKISLTRVGVTNLKKLVRLKRTNKRPIILLSTFEVFVNLPSSQKGIHMSRNPEVIEGIIDEALE
LESYEMETICEEIVKRLFEKHEYATEAEVFMVSDFMTKEKSPISGKYSQEIHKIMGGAKGIKKDDEIELTKIVGAEVVGI
TACPCAQNLIKEICIKNLKEKGFSDEDIDKILDSVIFATHNQRGIGRIILEVPTGYDIEIMDIIEIIKKSMSAEIHGILK
RADEAYVVEQSHKNPKFVEDCVREMAKRVVEKFKHLPDETKVLIRQINMESIHRHDAFAEKVATLGELRRELLSYE
>Mature_316_residues
MKMMNWRCDVQNFEPDVKISLTRVGVTNLKKLVRLKRTNKRPIILLSTFEVFVNLPSSQKGIHMSRNPEVIEGIIDEALE
LESYEMETICEEIVKRLFEKHEYATEAEVFMVSDFMTKEKSPISGKYSQEIHKIMGGAKGIKKDDEIELTKIVGAEVVGI
TACPCAQNLIKEICIKNLKEKGFSDEDIDKILDSVIFATHNQRGIGRIILEVPTGYDIEIMDIIEIIKKSMSAEIHGILK
RADEAYVVEQSHKNPKFVEDCVREMAKRVVEKFKHLPDETKVLIRQINMESIHRHDAFAEKVATLGELRRELLSYE

Specific function: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. It is also able to utilize a variety of GTP analogs as substrates, including GDP, beta,gamma-methylene-GTP and GTP- [gamm

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003801
- InterPro:   IPR022840
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: NA

Molecular weight: Translated: 36264; Mature: 36264

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMMNWRCDVQNFEPDVKISLTRVGVTNLKKLVRLKRTNKRPIILLSTFEVFVNLPSSQK
CCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCC
GIHMSRNPEVIEGIIDEALELESYEMETICEEIVKRLFEKHEYATEAEVFMVSDFMTKEK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
SPISGKYSQEIHKIMGGAKGIKKDDEIELTKIVGAEVVGITACPCAQNLIKEICIKNLKE
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHEEEECHHHHHHHHHHHHHHHHH
KGFSDEDIDKILDSVIFATHNQRGIGRIILEVPTGYDIEIMDIIEIIKKSMSAEIHGILK
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RADEAYVVEQSHKNPKFVEDCVREMAKRVVEKFKHLPDETKVLIRQINMESIHRHDAFAE
HCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHH
KVATLGELRRELLSYE
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKMMNWRCDVQNFEPDVKISLTRVGVTNLKKLVRLKRTNKRPIILLSTFEVFVNLPSSQK
CCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCC
GIHMSRNPEVIEGIIDEALELESYEMETICEEIVKRLFEKHEYATEAEVFMVSDFMTKEK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
SPISGKYSQEIHKIMGGAKGIKKDDEIELTKIVGAEVVGITACPCAQNLIKEICIKNLKE
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHEEEECHHHHHHHHHHHHHHHHH
KGFSDEDIDKILDSVIFATHNQRGIGRIILEVPTGYDIEIMDIIEIIKKSMSAEIHGILK
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RADEAYVVEQSHKNPKFVEDCVREMAKRVVEKFKHLPDETKVLIRQINMESIHRHDAFAE
HCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHH
KVATLGELRRELLSYE
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]