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The map label for this gene is 15668897

Identifier: 15668897

GI number: 15668897

Start: 648924

End: 649940

Strand: Direct

Name: 15668897

Synonym: MJ0715

Alternate gene names: NA

Gene position: 648924-649940 (Clockwise)

Preceding gene: 15668896

Following gene: 15668902

Centisome position: 38.98

GC content: 35.79

Gene sequence:

>1017_bases
ATGAAAATATCAATATATGGAGCTGGGAATCAGAGGCTTTATTTAGAACAGTTGAAAGTTCCAGAAAAGTTTGGTGGGGA
GCCACCTTATGGAGGAGCTGGAATGGCTATTGAATTTGCTAAGGCAGGACATGATGTTGTTTTATCTGAACCAAATAGGG
ATGTTATGAGTGATGATTTATGGAAGAAGGTTGAGGATGCTGGAGTTAAGGTTGTTAGTGATGATATCGAAGCTGCAAAG
CATGGGGAAATTCATGTTTTATTTACACCATTCGGAAGAATAACATTAAACATTGCAAATACAATTATTGAACATGTTCC
AGAGAATGCAATTATTTGTAACACTTGTACTATCCCAACTCCTGTTTTGTATAGGTCGTTGGAGGGAATTTTAAGATTAA
AGAGGAGAGATGTTGGTATTAGCTCAATGCACCCAACAGGAGTTCCTGGAACTCCTTCTCAAAAATATTACACAATTGCA
GGAAAAGCTTTGGAAGGAAAAGAGTATGCAACAGAAGATCAGATAAATAAATTAGTTGAATTGGTAAAAAGCGTTGGAAA
GATTCCTTATGTAACTCCTGCAGATGTTGTTCCTGCAGTTGCGGATATGGGGGCTTTAGTCACTGCAGTTGCCTTAGTTG
GAGTTTTGGATTATTATAGGGTTGGAACGCAGATTATCAACGCTCCAAAGGATATGATAGAAAAGCAAATATTGATATCT
TTACAAACAATTGCTTCAATTATTGAAACTTCTGGAATGGAGGGATTAATGAAAGTATTTAACAAAGACGCTTTACTTTC
ATCTGCAAAGAACATGTTAATTGATGAAAGACAGGAGGATTTAAATTTAGCTTTAAAGATTATTGAAGAGTTTGATAAAT
CAACTATTGGAGAGAAAGATATCAGCCAGACCTATTTAGTAGCTCCACAGGCGCTAATAAAAGAGGCAGTATCATTAATT
GGAAAGAGTGCTGTTGAGGGGATGATTAGAAGAAGTTCAAATAAATTATTCAAATAA

Upstream 100 bases:

>100_bases
TGGGTTTAATTAGAATAACAATGAAAAGAGCGGCAGATAAGATAAAAGCAATGTTTTAAATAAATTCTAATCCTTCAAAA
TTTACAATGAGGGATTTGGA

Downstream 100 bases:

>100_bases
TCATAATAAAGTAATACTTATACTGAATATTCGAAATTATTATTTTGGAATTTTACAATATAGGTGATATTATGGCATTA
AAATTCACCATTGAAGAGTT

Product: H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-like protein

Products: 5,10-methenyltetrahydromethanopterin; reduced coenzyme F420

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKISIYGAGNQRLYLEQLKVPEKFGGEPPYGGAGMAIEFAKAGHDVVLSEPNRDVMSDDLWKKVEDAGVKVVSDDIEAAK
HGEIHVLFTPFGRITLNIANTIIEHVPENAIICNTCTIPTPVLYRSLEGILRLKRRDVGISSMHPTGVPGTPSQKYYTIA
GKALEGKEYATEDQINKLVELVKSVGKIPYVTPADVVPAVADMGALVTAVALVGVLDYYRVGTQIINAPKDMIEKQILIS
LQTIASIIETSGMEGLMKVFNKDALLSSAKNMLIDERQEDLNLALKIIEEFDKSTIGEKDISQTYLVAPQALIKEAVSLI
GKSAVEGMIRRSSNKLFK

Sequences:

>Translated_338_residues
MKISIYGAGNQRLYLEQLKVPEKFGGEPPYGGAGMAIEFAKAGHDVVLSEPNRDVMSDDLWKKVEDAGVKVVSDDIEAAK
HGEIHVLFTPFGRITLNIANTIIEHVPENAIICNTCTIPTPVLYRSLEGILRLKRRDVGISSMHPTGVPGTPSQKYYTIA
GKALEGKEYATEDQINKLVELVKSVGKIPYVTPADVVPAVADMGALVTAVALVGVLDYYRVGTQIINAPKDMIEKQILIS
LQTIASIIETSGMEGLMKVFNKDALLSSAKNMLIDERQEDLNLALKIIEEFDKSTIGEKDISQTYLVAPQALIKEAVSLI
GKSAVEGMIRRSSNKLFK
>Mature_338_residues
MKISIYGAGNQRLYLEQLKVPEKFGGEPPYGGAGMAIEFAKAGHDVVLSEPNRDVMSDDLWKKVEDAGVKVVSDDIEAAK
HGEIHVLFTPFGRITLNIANTIIEHVPENAIICNTCTIPTPVLYRSLEGILRLKRRDVGISSMHPTGVPGTPSQKYYTIA
GKALEGKEYATEDQINKLVELVKSVGKIPYVTPADVVPAVADMGALVTAVALVGVLDYYRVGTQIINAPKDMIEKQILIS
LQTIASIIETSGMEGLMKVFNKDALLSSAKNMLIDERQEDLNLALKIIEEFDKSTIGEKDISQTYLVAPQALIKEAVSLI
GKSAVEGMIRRSSNKLFK

Specific function: Unknown

COG id: COG4007

COG function: function code R; Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HMD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HMDX_METJA (Q58125)

Other databases:

- EMBL:   L77117
- PIR:   C64389
- RefSeq:   NP_247700.1
- ProteinModelPortal:   Q58125
- SMR:   Q58125
- GeneID:   1451593
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0715
- NMPDR:   fig|243232.1.peg.737
- TIGR:   MJ0715
- HOGENOM:   HBG541201
- OMA:   ICNTCTI
- ProtClustDB:   PRK12557
- BioCyc:   MJAN243232:MJ_0715-MONOMER
- GO:   GO:0005488
- GO:   GO:0015948
- InterPro:   IPR008927
- InterPro:   IPR010063
- InterPro:   IPR004889
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- TIGRFAMs:   TIGR01724

Pfam domain/function: PF03201 HMD; SSF48179 6DGDH_C_like

EC number: 1.5.99.9

Molecular weight: Translated: 36854; Mature: 36854

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISIYGAGNQRLYLEQLKVPEKFGGEPPYGGAGMAIEFAKAGHDVVLSEPNRDVMSDDL
CEEEEEECCCCEEEHHHHCCCHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCHHHHHH
WKKVEDAGVKVVSDDIEAAKHGEIHVLFTPFGRITLNIANTIIEHVPENAIICNTCTIPT
HHHHHHCCCEEEECHHHHHCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCCCCH
PVLYRSLEGILRLKRRDVGISSMHPTGVPGTPSQKYYTIAGKALEGKEYATEDQINKLVE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCEECCCCCCCHHHHHHHHH
LVKSVGKIPYVTPADVVPAVADMGALVTAVALVGVLDYYRVGTQIINAPKDMIEKQILIS
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LQTIASIIETSGMEGLMKVFNKDALLSSAKNMLIDERQEDLNLALKIIEEFDKSTIGEKD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ISQTYLVAPQALIKEAVSLIGKSAVEGMIRRSSNKLFK
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKISIYGAGNQRLYLEQLKVPEKFGGEPPYGGAGMAIEFAKAGHDVVLSEPNRDVMSDDL
CEEEEEECCCCEEEHHHHCCCHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCHHHHHH
WKKVEDAGVKVVSDDIEAAKHGEIHVLFTPFGRITLNIANTIIEHVPENAIICNTCTIPT
HHHHHHCCCEEEECHHHHHCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCCCCH
PVLYRSLEGILRLKRRDVGISSMHPTGVPGTPSQKYYTIAGKALEGKEYATEDQINKLVE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCEECCCCCCCHHHHHHHHH
LVKSVGKIPYVTPADVVPAVADMGALVTAVALVGVLDYYRVGTQIINAPKDMIEKQILIS
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LQTIASIIETSGMEGLMKVFNKDALLSSAKNMLIDERQEDLNLALKIIEEFDKSTIGEKD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ISQTYLVAPQALIKEAVSLIGKSAVEGMIRRSSNKLFK
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5,10-methylenetetrahydromethanopterin; coenzyme F420

Specific reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087