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The map label for this gene is rpl18p

Identifier: 15668651

GI number: 15668651

Start: 417835

End: 418422

Strand: Direct

Name: rpl18p

Synonym: MJ0474

Alternate gene names: 15668651

Gene position: 417835-418422 (Clockwise)

Preceding gene: 15668650

Following gene: 15668652

Centisome position: 25.1

GC content: 34.35

Gene sequence:

>588_bases
ATGGCAACAGGTCCAACTTATAGGGTTAAGTTTAGAAGAAGAAGAGAAGCAAAAACTGACTACAGAAAAAGATTAAAATT
ATTATTATCAAGAAAACCAAGATTAGTAGCAAGAAGAACTTTGAATCACTGCATTGCTCAAATTGTATTGTATGATGAGA
AGGGAGATAAAACAGTTGTTTCAGCTCATTCAAGAGAGTTGATTAAATTGGGTTATAAGGGGCATACAGGAAACTTGCCA
TCAGCATACTTAACAGGTTACTTATTAGGTAAGAAAGCTTTAGCCAAAGGTTACACTGAAGCAGTTTTAGATATTGGATT
GCACAGAGCTACAAAAGGTAATGCAATATTTGCAATATTAAAAGGAGCTTTAGATGCGGGTATGGAAATTCCACACGGAG
AAGAAATATTACCATCAGAAGAAAGGATAAGAGGGGAACACATAAAGGCTTATGCCGAAATGTTAAAAGAACAGGATGAA
GAAAGATACAAGAAACAGTTCTCAAAATATTTGGAGAAGGGATTAGAACCAGAAAAATTGCCAGAACACTTTGAAGAAAT
AAAGGCAAAAATAGACAGTATGTTCTAA

Upstream 100 bases:

>100_bases
AAGGAGGAGCATTTAGAAGTAGAAGCCACCTCTTCCTTTACATGAGAGAACACGAACTCTTAAAATAATTAAACAATTTT
TATCAGGAAGGTGAGAAATT

Downstream 100 bases:

>100_bases
AGGTGAGATTATGAGATTTAATATAGATGAGTGGGAACCAAAAACCACTATTGGAAGAATGGTTAAGGAAGGGCAGATAA
CTGATATTGATTACATTTTA

Product: 50S ribosomal protein L18P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MATGPTYRVKFRRRREAKTDYRKRLKLLLSRKPRLVARRTLNHCIAQIVLYDEKGDKTVVSAHSRELIKLGYKGHTGNLP
SAYLTGYLLGKKALAKGYTEAVLDIGLHRATKGNAIFAILKGALDAGMEIPHGEEILPSEERIRGEHIKAYAEMLKEQDE
ERYKKQFSKYLEKGLEPEKLPEHFEEIKAKIDSMF

Sequences:

>Translated_195_residues
MATGPTYRVKFRRRREAKTDYRKRLKLLLSRKPRLVARRTLNHCIAQIVLYDEKGDKTVVSAHSRELIKLGYKGHTGNLP
SAYLTGYLLGKKALAKGYTEAVLDIGLHRATKGNAIFAILKGALDAGMEIPHGEEILPSEERIRGEHIKAYAEMLKEQDE
ERYKKQFSKYLEKGLEPEKLPEHFEEIKAKIDSMF
>Mature_194_residues
ATGPTYRVKFRRRREAKTDYRKRLKLLLSRKPRLVARRTLNHCIAQIVLYDEKGDKTVVSAHSRELIKLGYKGHTGNLPS
AYLTGYLLGKKALAKGYTEAVLDIGLHRATKGNAIFAILKGALDAGMEIPHGEEILPSEERIRGEHIKAYAEMLKEQDEE
RYKKQFSKYLEKGLEPEKLPEHFEEIKAKIDSMF

Specific function: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance

COG id: COG0256

COG function: function code J; Ribosomal protein L18

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L18P family

Homologues:

Organism=Homo sapiens, GI14591909, Length=232, Percent_Identity=34.051724137931, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534333, Length=231, Percent_Identity=36.3636363636364, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6325126, Length=223, Percent_Identity=33.6322869955157, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI116007384, Length=227, Percent_Identity=32.5991189427313, Blast_Score=113, Evalue=7e-26,
Organism=Drosophila melanogaster, GI116007382, Length=227, Percent_Identity=32.5991189427313, Blast_Score=113, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL18_METJA (P54044)

Other databases:

- EMBL:   L77117
- PIR:   B64359
- RefSeq:   NP_247450.1
- ProteinModelPortal:   P54044
- SMR:   P54044
- GeneID:   1451336
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0474
- NMPDR:   fig|243232.1.peg.487
- TIGR:   MJ0474
- HOGENOM:   HBG391676
- OMA:   GNTPSAY
- ProtClustDB:   PRK08569
- BioCyc:   MJAN243232:MJ_0474-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_01337_A
- InterPro:   IPR005484
- InterPro:   IPR005485
- PANTHER:   PTHR23410

Pfam domain/function: PF00861 Ribosomal_L18p

EC number: NA

Molecular weight: Translated: 22354; Mature: 22223

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGPTYRVKFRRRREAKTDYRKRLKLLLSRKPRLVARRTLNHCIAQIVLYDEKGDKTVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
SAHSRELIKLGYKGHTGNLPSAYLTGYLLGKKALAKGYTEAVLDIGLHRATKGNAIFAIL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KGALDAGMEIPHGEEILPSEERIRGEHIKAYAEMLKEQDEERYKKQFSKYLEKGLEPEKL
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
PEHFEEIKAKIDSMF
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATGPTYRVKFRRRREAKTDYRKRLKLLLSRKPRLVARRTLNHCIAQIVLYDEKGDKTVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
SAHSRELIKLGYKGHTGNLPSAYLTGYLLGKKALAKGYTEAVLDIGLHRATKGNAIFAIL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KGALDAGMEIPHGEEILPSEERIRGEHIKAYAEMLKEQDEERYKKQFSKYLEKGLEPEKL
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
PEHFEEIKAKIDSMF
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087