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The map label for this gene is prmA [C]

Identifier: 15668459

GI number: 15668459

Start: 269168

End: 269827

Strand: Reverse

Name: prmA [C]

Synonym: MJ0284

Alternate gene names: 15668459

Gene position: 269827-269168 (Counterclockwise)

Preceding gene: 15668460

Following gene: 15668456

Centisome position: 16.21

GC content: 30.61

Gene sequence:

>660_bases
ATGATAAAGAAAAAGCATTTAGAAATGATGTTAGATTCTTTAAAAAGACATCCAAATCCAAAAGCTGATTTAGAGCAATA
TACAATAGACGGAAAATTAGCAGCTGATATTTTATTTTTTGCTGTGAATGATTTTTATAACAATGTTGTTATCGATTTAG
GTTGTGGAACTGGAAGATTAGCTATAGGTAGCAAAATTTTAGGAGCTAAGAGGGCTATTGGTATAGATATCGATAGGGAG
AGTATTGAAGCAGCTAAAGAGAACGCTAAAAAGCTAAATGTTGATGTAGATTTTTATTGCATGGACATTAGAGATGTTGA
TGATGAATTTTTAAATAATGTGCTTGGTGAAGATAGGGATTTAAAGAGAGTAGTTATTCAAAATCCTCCATTTGGAGCCC
AGAAAAAACATGCTGATAGAGTATTTTTAGATAAGGCGTTAGAGATTGGGGATATTATTTATACTATTCACAATTATCCA
ACAAAGGATTTTGTTATTAAGTATGTTGAAGATAAAGGGGGAAAAATAACTCACATCTATGAGGCATTTTTTAGAATTCC
TGCAATATACGAGTTTCATAAAAAAAAGGTTGTGGAGATTCCTGTAGTGATTTTTAGAATAGAGAAATTAGGGTTCGAAA
CAGTTTTTAATTTTCTATAA

Upstream 100 bases:

>100_bases
CCTCAATTAAGAAAGGAATCAACATTGAATAAATTGGCTAATTTTCTTTATTTTTATACTAAATAACATCTATATAATTA
CATATTTAGATGGTGAAGAG

Downstream 100 bases:

>100_bases
CTTACAGTAGCATATCATAATAAACAATATCACAATATAAATATTGTTTTTTTATTAAAATAGTAATATGTATTGTTATA
TCATAATGTTAATGAGGAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MIKKKHLEMMLDSLKRHPNPKADLEQYTIDGKLAADILFFAVNDFYNNVVIDLGCGTGRLAIGSKILGAKRAIGIDIDRE
SIEAAKENAKKLNVDVDFYCMDIRDVDDEFLNNVLGEDRDLKRVVIQNPPFGAQKKHADRVFLDKALEIGDIIYTIHNYP
TKDFVIKYVEDKGGKITHIYEAFFRIPAIYEFHKKKVVEIPVVIFRIEKLGFETVFNFL

Sequences:

>Translated_219_residues
MIKKKHLEMMLDSLKRHPNPKADLEQYTIDGKLAADILFFAVNDFYNNVVIDLGCGTGRLAIGSKILGAKRAIGIDIDRE
SIEAAKENAKKLNVDVDFYCMDIRDVDDEFLNNVLGEDRDLKRVVIQNPPFGAQKKHADRVFLDKALEIGDIIYTIHNYP
TKDFVIKYVEDKGGKITHIYEAFFRIPAIYEFHKKKVVEIPVVIFRIEKLGFETVFNFL
>Mature_219_residues
MIKKKHLEMMLDSLKRHPNPKADLEQYTIDGKLAADILFFAVNDFYNNVVIDLGCGTGRLAIGSKILGAKRAIGIDIDRE
SIEAAKENAKKLNVDVDFYCMDIRDVDDEFLNNVLGEDRDLKRVVIQNPPFGAQKKHADRVFLDKALEIGDIIYTIHNYP
TKDFVIKYVEDKGGKITHIYEAFFRIPAIYEFHKKKVVEIPVVIFRIEKLGFETVFNFL

Specific function: Methylates Ribosomal Protein L11. [C]

COG id: COG2263

COG function: function code J; Predicted RNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI92859575, Length=210, Percent_Identity=36.6666666666667, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17552558, Length=222, Percent_Identity=27.9279279279279, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221512926, Length=213, Percent_Identity=28.6384976525822, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28574609, Length=213, Percent_Identity=28.6384976525822, Blast_Score=87, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y284_METJA (Q57732)

Other databases:

- EMBL:   L77117
- PIR:   E64335
- RefSeq:   NP_247257.1
- ProteinModelPortal:   Q57732
- SMR:   Q57732
- GeneID:   1451139
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0284
- NMPDR:   fig|243232.1.peg.294
- TIGR:   MJ0284
- HOGENOM:   HBG539631
- OMA:   VIAELRY
- ProtClustDB:   CLSK876143
- BioCyc:   MJAN243232:MJ_0284-MONOMER
- GO:   GO:0005737
- InterPro:   IPR010456

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 25139; Mature: 25139

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKKHLEMMLDSLKRHPNPKADLEQYTIDGKLAADILFFAVNDFYNNVVIDLGCGTGRL
CCCHHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHHHHHHHHHCCEEEECCCCCCCH
AIGSKILGAKRAIGIDIDRESIEAAKENAKKLNVDVDFYCMDIRDVDDEFLNNVLGEDRD
HHCHHHHCCCCEEEECCCHHHHHHHHHHHHEECCEEEEEEEECCCCCHHHHHHHHCCCCC
LKRVVIQNPPFGAQKKHADRVFLDKALEIGDIIYTIHNYPTKDFVIKYVEDKGGKITHIY
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHEEEEEECCCCEEHHHH
EAFFRIPAIYEFHKKKVVEIPVVIFRIEKLGFETVFNFL
HHHHHCHHHHHHHHHHHHHHHHEEEHHHHHCHHHHHHCC
>Mature Secondary Structure
MIKKKHLEMMLDSLKRHPNPKADLEQYTIDGKLAADILFFAVNDFYNNVVIDLGCGTGRL
CCCHHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHHHHHHHHHCCEEEECCCCCCCH
AIGSKILGAKRAIGIDIDRESIEAAKENAKKLNVDVDFYCMDIRDVDDEFLNNVLGEDRD
HHCHHHHCCCCEEEECCCHHHHHHHHHHHHEECCEEEEEEEECCCCCHHHHHHHHCCCCC
LKRVVIQNPPFGAQKKHADRVFLDKALEIGDIIYTIHNYPTKDFVIKYVEDKGGKITHIY
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHEEEEEECCCCEEHHHH
EAFFRIPAIYEFHKKKVVEIPVVIFRIEKLGFETVFNFL
HHHHHCHHHHHHHHHHHHHHHHEEEHHHHHCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087