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The map label for this gene is 15668431

Identifier: 15668431

GI number: 15668431

Start: 242761

End: 243696

Strand: Direct

Name: 15668431

Synonym: MJ0257

Alternate gene names: NA

Gene position: 242761-243696 (Clockwise)

Preceding gene: 15668429

Following gene: 15668436

Centisome position: 14.58

GC content: 32.37

Gene sequence:

>936_bases
ATGATTCCAGAAGAAATTTATAAAATTTTAAGAAAGCAGAGGTATCAAATAGACGGCCACACAGCCGTTAAGTTGTGTGG
ATGGGTTAGAAAAAAGATGTTAGAGGATAAAAATTGCTATAAATCAAAATTCTATGGTATTGAAACACACAGATGTATTC
AATGCACACCATCAGTTATTTGGTGTCAGCAAAATTGTATATTCTGCTGGAGAGTTTTACCAAGGGATATAGGTATAGAT
ATAAGCCAAATTAAAGAACCAAAATGGGAAGAGCCAGAGGTTGTATATGAGAAAATTTTAGCCATGCATAAAAGAATAAT
TATGGGTTATGCTGGAGTGTTAGATAGAGTTGGAGAGAAGAAATTTAAAGAGGCTTTAGAGCCAAAGCATGTGGCAATAT
CTTTATCAGGAGAGCCAACACTTTATCCATACTTAGATGAGTTAATAAAGATATTCCATAAGAATGGATTTACAACATTT
GTTGTTTCAAATGGAATCTTAACTGATGTTATTGAAAAAATAGAGCCAACTCAACTGTATATCTCATTAGATGCCTATGA
TTTGGACAGTTATAGAAGAATATGTGGGGGGAAGAAAGAGTATTGGGAAAGTATCTTAAATACCTTAGACATTTTAAAAG
AGAAGAAGAGAACTTGTATAAGAACTACTTTAATTAGGGGCTATAATGATGATATCTTAAAGTTTGTAGAGCTCTATGAA
AGAGCTGATGTCCATTTCATTGAGTTAAAGTCATATATGCACGTTGGTTATTCTCAAAAAAGATTAAAGAAAGAGGACAT
GCTACAACATGATGAGATATTAAAATTAGCTAAGATGTTAGATGAAAACAGCTCATACAAATTAATTGATGACAGTGAAG
ATAGTAGAGTGGCGTTATTGCAAAATGAAAATAGGAAAATCAACCCGAAACTTTAA

Upstream 100 bases:

>100_bases
AATAGGGGGTTTCCCCCTATGGAGATATAGATTTATGGAAGCGATAAAAAGGAGCCAAAAATATCATTCATTAAAATAAA
TAAATATTTAAAGTGAGAGT

Downstream 100 bases:

>100_bases
TAAAGTTTCATCAAAGCTAACATCTCTGCCAAAGGCAGAGGTGTAAATGGGGTATCCCAATAGGGCGAAGCCCTATGGTT
GTAAAATGAAAATAGAAAGA

Product: tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIPEEIYKILRKQRYQIDGHTAVKLCGWVRKKMLEDKNCYKSKFYGIETHRCIQCTPSVIWCQQNCIFCWRVLPRDIGID
ISQIKEPKWEEPEVVYEKILAMHKRIIMGYAGVLDRVGEKKFKEALEPKHVAISLSGEPTLYPYLDELIKIFHKNGFTTF
VVSNGILTDVIEKIEPTQLYISLDAYDLDSYRRICGGKKEYWESILNTLDILKEKKRTCIRTTLIRGYNDDILKFVELYE
RADVHFIELKSYMHVGYSQKRLKKEDMLQHDEILKLAKMLDENSSYKLIDDSEDSRVALLQNENRKINPKL

Sequences:

>Translated_311_residues
MIPEEIYKILRKQRYQIDGHTAVKLCGWVRKKMLEDKNCYKSKFYGIETHRCIQCTPSVIWCQQNCIFCWRVLPRDIGID
ISQIKEPKWEEPEVVYEKILAMHKRIIMGYAGVLDRVGEKKFKEALEPKHVAISLSGEPTLYPYLDELIKIFHKNGFTTF
VVSNGILTDVIEKIEPTQLYISLDAYDLDSYRRICGGKKEYWESILNTLDILKEKKRTCIRTTLIRGYNDDILKFVELYE
RADVHFIELKSYMHVGYSQKRLKKEDMLQHDEILKLAKMLDENSSYKLIDDSEDSRVALLQNENRKINPKL
>Mature_311_residues
MIPEEIYKILRKQRYQIDGHTAVKLCGWVRKKMLEDKNCYKSKFYGIETHRCIQCTPSVIWCQQNCIFCWRVLPRDIGID
ISQIKEPKWEEPEVVYEKILAMHKRIIMGYAGVLDRVGEKKFKEALEPKHVAISLSGEPTLYPYLDELIKIFHKNGFTTF
VVSNGILTDVIEKIEPTQLYISLDAYDLDSYRRICGGKKEYWESILNTLDILKEKKRTCIRTTLIRGYNDDILKFVELYE
RADVHFIELKSYMHVGYSQKRLKKEDMLQHDEILKLAKMLDENSSYKLIDDSEDSRVALLQNENRKINPKL

Specific function: Unknown

COG id: COG0731

COG function: function code C; Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0026 family

Homologues:

Organism=Homo sapiens, GI50726981, Length=317, Percent_Identity=32.807570977918, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI224282123, Length=267, Percent_Identity=29.9625468164794, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI224282125, Length=261, Percent_Identity=29.8850574712644, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6325049, Length=319, Percent_Identity=31.974921630094, Blast_Score=159, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y257_METJA (Q57705)

Other databases:

- EMBL:   L77117
- PIR:   B64332
- RefSeq:   NP_247229.1
- PDB:   2Z2U
- PDBsum:   2Z2U
- ProteinModelPortal:   Q57705
- SMR:   Q57705
- GeneID:   1451111
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0257
- NMPDR:   fig|243232.1.peg.266
- TIGR:   MJ0257
- HOGENOM:   HBG460802
- OMA:   LSGEPTM
- ProtClustDB:   PRK13762
- BioCyc:   MJAN243232:MJ_0257-MONOMER
- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR013917
- SMART:   SM00729

Pfam domain/function: PF04055 Radical_SAM; PF08608 Wyosine_form

EC number: NA

Molecular weight: Translated: 36712; Mature: 36712

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPEEIYKILRKQRYQIDGHTAVKLCGWVRKKMLEDKNCYKSKFYGIETHRCIQCTPSVI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHEECCCCEE
WCQQNCIFCWRVLPRDIGIDISQIKEPKWEEPEVVYEKILAMHKRIIMGYAGVLDRVGEK
EECCCHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFKEALEPKHVAISLSGEPTLYPYLDELIKIFHKNGFTTFVVSNGILTDVIEKIEPTQLY
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEE
ISLDAYDLDSYRRICGGKKEYWESILNTLDILKEKKRTCIRTTLIRGYNDDILKFVELYE
EEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RADVHFIELKSYMHVGYSQKRLKKEDMLQHDEILKLAKMLDENSSYKLIDDSEDSRVALL
HCCCEEEEHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEE
QNENRKINPKL
ECCCCCCCCCC
>Mature Secondary Structure
MIPEEIYKILRKQRYQIDGHTAVKLCGWVRKKMLEDKNCYKSKFYGIETHRCIQCTPSVI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHEECCCCEE
WCQQNCIFCWRVLPRDIGIDISQIKEPKWEEPEVVYEKILAMHKRIIMGYAGVLDRVGEK
EECCCHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFKEALEPKHVAISLSGEPTLYPYLDELIKIFHKNGFTTFVVSNGILTDVIEKIEPTQLY
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEE
ISLDAYDLDSYRRICGGKKEYWESILNTLDILKEKKRTCIRTTLIRGYNDDILKFVELYE
EEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RADVHFIELKSYMHVGYSQKRLKKEDMLQHDEILKLAKMLDENSSYKLIDDSEDSRVALL
HCCCEEEEHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEE
QNENRKINPKL
ECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087