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The map label for this gene is atpA [H]

Identifier: 15668390

GI number: 15668390

Start: 207184

End: 208968

Strand: Reverse

Name: atpA [H]

Synonym: MJ0217

Alternate gene names: 15668390

Gene position: 208968-207184 (Counterclockwise)

Preceding gene: 15668391

Following gene: 15668389

Centisome position: 12.55

GC content: 38.26

Gene sequence:

>1785_bases
ATGAAAAGAGAGGTTGAGAATATGCCAGTTGTTGGTAAGATTATTAAAATCGCAGGGCCTGTTGTAGTTGCAGAGGGAAT
GAAAGGAGCTCAGATGTATGAGGTCGTTAAAGTAGGAGAAGAGAAATTGACTGGAGAAATCATTCAGTTGCACGATGATA
AAGCAGTTATTCAGGTTTATGAAGAAACATCTGGAATTAAACCAGGAGAGCCAGTTGTTGGTACTGGAGCTCCATTGTCT
GTTGAATTAGGGCCAGGGATGTTAAGAGCTATGTATGATGGTATTCAGAGGCCTTTAACAGCAATTGAAGAGAAAACAGG
TTCAATCTTTATCCCAAGAGGAGTTGATGTCCCTGCATTACCAAGAGATATAAAATGGGAATTTAAACCAGTGGTAAATG
AAGGAGATTATGTTGAAGAAGGAGACATAATTGGAACTGTTGATGAAACTCCTTCAATAGTTCATAAAATCTTAGTTCCA
ATTGGTGTTAAAGGAAAAATTGTTGAAATAAAAGAGGGTAAATTTACAGTTGAAGAGACAGTTGCAGTTGTAGAAACAGA
AAATGGAGAAAGGAAAGAAATTACAATGATGCAAAAATGGCCAGTAAGAAAACCAAGACCATATAAAGAGAAACTACCTC
CAGAAATTCCATTAATTACAGGGCAAAGAGTTGAAGACACTTTCTTTACATTAGCAAAAGGAGGAACAGCAGCAATTCCA
GGTCCATTCGGTTCAGGAAAAACGGTTACTCAGCATCAGTTGGCAAAGTGGTCTGACGCTGATGTCGTTGTTTATATCGG
ATGTGGAGAAAGAGGAAACGAGATGACAGAGGTTATTGAAGAGTTCCCACACTTAGAAGATATTAGAACTGGAAACAAAT
TAATGGATAGAACTGTATTAATAGCCAACACATCAAACATGCCTGTCGCTGCAAGGGAAGCATCTGTCTATACAGGAATT
ACAATTGCAGAGTACTTCAGAGATATGGGTTATGGAGTTTTATTAACAGCAGATTCAACATCAAGATGGGCAGAGGCAAT
GAGAGAAATTTCAGGTAGATTGGAAGAAATGCCAGGGGAAGAAGGGTATCCAGCATACTTAGCTTCAAGATTGGCTCAGT
TCTATGAAAGAGCTGGAAGAGTTATAACCTTAGGGAAAGATAACAGACAAGGATTCGTTTGTATCGTTGGAGCTGTTTCA
CCACCAGGAGGGGACTTCTCAGAACCAGTTACATCAAACACACTAAGGATAGTTAAGGTATTCTGGGCGTTAGATGCAAA
CTTGGCAAGAAGAAGACACTTCCCAGCTATCAACTGGTTGCAGAGTTATTCATTATACATTGATGATGTTACAGAGTGGT
GGAACACAAATACTGGTCCAGATTGGAGACAATTAAGAGATGAAGCAATGAGCTTATTACAAAAAGAGGCAGAGTTGCAA
GAGATTGTTCAGTTAGTTGGGCCTGATGCATTGCCAGATAGGGAGAGAGTTATTTTAGAAGTTGCAAGAATGTTGAGGGA
GGATTTCTTACAGCAAGATGCGTTTGATGAGGTAGATACCTACTGTCCTCCAATGAAACAGTACTTAATGTTAAAGATAA
TTATGACATTCTACCAAGAAGCATTGAAGGCAGTTGAAAGAGGAGTTGAACCAGCTAAGATTTTAGGAGTTTCAGTTAAG
CAAGATATTGCAAGAATGAAATACATCCCACACGATGAGTTTATAAATGTTAAATCAAAAGAAATAATGGAGAAAATTAA
GAATGAATTAGGTTCATTAAACTAA

Upstream 100 bases:

>100_bases
TGAGAGAATAGACCCAGTTAAAGAGTTAATAAGAAAAGCAATTGGAGTTTCAATGAAATAATGATAACTAAGATTACGAT
AAAACCAATAAAAACGTTAA

Downstream 100 bases:

>100_bases
ATTCCTTTCCTTAAAACTTTACAAACTCTTTATTTGAGGTGATGATATGGCTACAGCAGCATCAGCAATTGAATACTCAT
CAGTTAAGAGTATTGCAGGA

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MKREVENMPVVGKIIKIAGPVVVAEGMKGAQMYEVVKVGEEKLTGEIIQLHDDKAVIQVYEETSGIKPGEPVVGTGAPLS
VELGPGMLRAMYDGIQRPLTAIEEKTGSIFIPRGVDVPALPRDIKWEFKPVVNEGDYVEEGDIIGTVDETPSIVHKILVP
IGVKGKIVEIKEGKFTVEETVAVVETENGERKEITMMQKWPVRKPRPYKEKLPPEIPLITGQRVEDTFFTLAKGGTAAIP
GPFGSGKTVTQHQLAKWSDADVVVYIGCGERGNEMTEVIEEFPHLEDIRTGNKLMDRTVLIANTSNMPVAAREASVYTGI
TIAEYFRDMGYGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLASRLAQFYERAGRVITLGKDNRQGFVCIVGAVS
PPGGDFSEPVTSNTLRIVKVFWALDANLARRRHFPAINWLQSYSLYIDDVTEWWNTNTGPDWRQLRDEAMSLLQKEAELQ
EIVQLVGPDALPDRERVILEVARMLREDFLQQDAFDEVDTYCPPMKQYLMLKIIMTFYQEALKAVERGVEPAKILGVSVK
QDIARMKYIPHDEFINVKSKEIMEKIKNELGSLN

Sequences:

>Translated_594_residues
MKREVENMPVVGKIIKIAGPVVVAEGMKGAQMYEVVKVGEEKLTGEIIQLHDDKAVIQVYEETSGIKPGEPVVGTGAPLS
VELGPGMLRAMYDGIQRPLTAIEEKTGSIFIPRGVDVPALPRDIKWEFKPVVNEGDYVEEGDIIGTVDETPSIVHKILVP
IGVKGKIVEIKEGKFTVEETVAVVETENGERKEITMMQKWPVRKPRPYKEKLPPEIPLITGQRVEDTFFTLAKGGTAAIP
GPFGSGKTVTQHQLAKWSDADVVVYIGCGERGNEMTEVIEEFPHLEDIRTGNKLMDRTVLIANTSNMPVAAREASVYTGI
TIAEYFRDMGYGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLASRLAQFYERAGRVITLGKDNRQGFVCIVGAVS
PPGGDFSEPVTSNTLRIVKVFWALDANLARRRHFPAINWLQSYSLYIDDVTEWWNTNTGPDWRQLRDEAMSLLQKEAELQ
EIVQLVGPDALPDRERVILEVARMLREDFLQQDAFDEVDTYCPPMKQYLMLKIIMTFYQEALKAVERGVEPAKILGVSVK
QDIARMKYIPHDEFINVKSKEIMEKIKNELGSLN
>Mature_594_residues
MKREVENMPVVGKIIKIAGPVVVAEGMKGAQMYEVVKVGEEKLTGEIIQLHDDKAVIQVYEETSGIKPGEPVVGTGAPLS
VELGPGMLRAMYDGIQRPLTAIEEKTGSIFIPRGVDVPALPRDIKWEFKPVVNEGDYVEEGDIIGTVDETPSIVHKILVP
IGVKGKIVEIKEGKFTVEETVAVVETENGERKEITMMQKWPVRKPRPYKEKLPPEIPLITGQRVEDTFFTLAKGGTAAIP
GPFGSGKTVTQHQLAKWSDADVVVYIGCGERGNEMTEVIEEFPHLEDIRTGNKLMDRTVLIANTSNMPVAAREASVYTGI
TIAEYFRDMGYGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLASRLAQFYERAGRVITLGKDNRQGFVCIVGAVS
PPGGDFSEPVTSNTLRIVKVFWALDANLARRRHFPAINWLQSYSLYIDDVTEWWNTNTGPDWRQLRDEAMSLLQKEAELQ
EIVQLVGPDALPDRERVILEVARMLREDFLQQDAFDEVDTYCPPMKQYLMLKIIMTFYQEALKAVERGVEPAKILGVSVK
QDIARMKYIPHDEFINVKSKEIMEKIKNELGSLN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=540, Percent_Identity=55.3703703703704, Blast_Score=600, Evalue=1e-171,
Organism=Homo sapiens, GI32189394, Length=388, Percent_Identity=27.0618556701031, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI19913428, Length=227, Percent_Identity=27.7533039647577, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI19913426, Length=259, Percent_Identity=26.6409266409266, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI50345984, Length=235, Percent_Identity=25.531914893617, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI4757810, Length=235, Percent_Identity=25.531914893617, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1790170, Length=373, Percent_Identity=29.2225201072386, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788251, Length=311, Percent_Identity=27.9742765273312, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790172, Length=242, Percent_Identity=26.4462809917355, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=544, Percent_Identity=55.5147058823529, Blast_Score=599, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI25144756, Length=301, Percent_Identity=29.2358803986711, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17510931, Length=225, Percent_Identity=30.2222222222222, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17570191, Length=255, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=448, Percent_Identity=25.8928571428571, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71988080, Length=323, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71988074, Length=242, Percent_Identity=26.4462809917355, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320016, Length=328, Percent_Identity=49.6951219512195, Blast_Score=333, Evalue=5e-92,
Organism=Saccharomyces cerevisiae, GI6322581, Length=364, Percent_Identity=27.7472527472527, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319603, Length=245, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319370, Length=235, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129479, Length=580, Percent_Identity=53.1034482758621, Blast_Score=613, Evalue=1e-176,
Organism=Drosophila melanogaster, GI24583988, Length=540, Percent_Identity=55.5555555555556, Blast_Score=604, Evalue=1e-173,
Organism=Drosophila melanogaster, GI24583986, Length=540, Percent_Identity=55.5555555555556, Blast_Score=604, Evalue=1e-173,
Organism=Drosophila melanogaster, GI24583984, Length=540, Percent_Identity=55.5555555555556, Blast_Score=604, Evalue=1e-173,
Organism=Drosophila melanogaster, GI24583992, Length=563, Percent_Identity=53.8188277087034, Blast_Score=597, Evalue=1e-171,
Organism=Drosophila melanogaster, GI28574560, Length=304, Percent_Identity=31.5789473684211, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24638766, Length=302, Percent_Identity=29.8013245033113, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281361666, Length=266, Percent_Identity=26.6917293233083, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24646341, Length=266, Percent_Identity=26.6917293233083, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17136796, Length=266, Percent_Identity=26.6917293233083, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24658560, Length=236, Percent_Identity=25.4237288135593, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005726
- InterPro:   IPR003593
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 66445; Mature: 66445

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKREVENMPVVGKIIKIAGPVVVAEGMKGAQMYEVVKVGEEKLTGEIIQLHDDKAVIQVY
CCCCCCCCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHCHHHHCCCCEEEECCCEEEEEE
EETSGIKPGEPVVGTGAPLSVELGPGMLRAMYDGIQRPLTAIEEKTGSIFIPRGVDVPAL
HHHCCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
PRDIKWEFKPVVNEGDYVEEGDIIGTVDETPSIVHKILVPIGVKGKIVEIKEGKFTVEET
CCCCCEEEEECCCCCCEEECCCEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCEEHHHE
VAVVETENGERKEITMMQKWPVRKPRPYKEKLPPEIPLITGQRVEDTFFTLAKGGTAAIP
EEEEECCCCCCCEEEEHHHCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEECC
GPFGSGKTVTQHQLAKWSDADVVVYIGCGERGNEMTEVIEEFPHLEDIRTGNKLMDRTVL
CCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCHHHCCEEE
IANTSNMPVAAREASVYTGITIAEYFRDMGYGVLLTADSTSRWAEAMREISGRLEEMPGE
EEECCCCCEEECCCHHHCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCC
EGYPAYLASRLAQFYERAGRVITLGKDNRQGFVCIVGAVSPPGGDFSEPVTSNTLRIVKV
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHH
FWALDANLARRRHFPAINWLQSYSLYIDDVTEWWNTNTGPDWRQLRDEAMSLLQKEAELQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
EIVQLVGPDALPDRERVILEVARMLREDFLQQDAFDEVDTYCPPMKQYLMLKIIMTFYQE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHH
ALKAVERGVEPAKILGVSVKQDIARMKYIPHDEFINVKSKEIMEKIKNELGSLN
HHHHHHCCCCCHHHCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKREVENMPVVGKIIKIAGPVVVAEGMKGAQMYEVVKVGEEKLTGEIIQLHDDKAVIQVY
CCCCCCCCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHCHHHHCCCCEEEECCCEEEEEE
EETSGIKPGEPVVGTGAPLSVELGPGMLRAMYDGIQRPLTAIEEKTGSIFIPRGVDVPAL
HHHCCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
PRDIKWEFKPVVNEGDYVEEGDIIGTVDETPSIVHKILVPIGVKGKIVEIKEGKFTVEET
CCCCCEEEEECCCCCCEEECCCEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCEEHHHE
VAVVETENGERKEITMMQKWPVRKPRPYKEKLPPEIPLITGQRVEDTFFTLAKGGTAAIP
EEEEECCCCCCCEEEEHHHCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEECC
GPFGSGKTVTQHQLAKWSDADVVVYIGCGERGNEMTEVIEEFPHLEDIRTGNKLMDRTVL
CCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCHHHCCEEE
IANTSNMPVAAREASVYTGITIAEYFRDMGYGVLLTADSTSRWAEAMREISGRLEEMPGE
EEECCCCCEEECCCHHHCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCC
EGYPAYLASRLAQFYERAGRVITLGKDNRQGFVCIVGAVSPPGGDFSEPVTSNTLRIVKV
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHH
FWALDANLARRRHFPAINWLQSYSLYIDDVTEWWNTNTGPDWRQLRDEAMSLLQKEAELQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
EIVQLVGPDALPDRERVILEVARMLREDFLQQDAFDEVDTYCPPMKQYLMLKIIMTFYQE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHH
ALKAVERGVEPAKILGVSVKQDIARMKYIPHDEFINVKSKEIMEKIKNELGSLN
HHHHHHCCCCCHHHCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]