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The map label for this gene is sucC

Identifier: 15668382

GI number: 15668382

Start: 201040

End: 202134

Strand: Direct

Name: sucC

Synonym: MJ0210

Alternate gene names: 15668382

Gene position: 201040-202134 (Clockwise)

Preceding gene: 15668379

Following gene: 15668383

Centisome position: 12.07

GC content: 32.15

Gene sequence:

>1095_bases
ATGAAACTACATGAATATGAAGCTAAAAATATATTTAAAAAGTATGGTATCCCAGTTCCTGAGAGCTTTTTAGTATCTAA
GGAAGATGATTTAAACAGTATAAATGTTGATAAAGAAGTTGTTTTAAAAGCCCAAGTTTTAGTTGGTGGAAGAGGAAAAG
CAGGAGGAATTTTATTTGCATCAAATAAAGAAGAATTCATAAAGAAAGCAGAAGAGTTGTTTAATAAAGAAGTTAAAGGA
GAAAAAGTTGAAAAAATTTTAGTTGAAGAGAAATTGCCAATAGAAAAAGAATACTATGTATCAATTATCATAGACAGAGA
TGCTAAAAAACCGTTAATCATCTTCTCAACTGAGGGAGGAGTTGATATTGAAGAAGTCGCTGAAAAGAATCCAGAAAAGA
TTATAAAGTACCATATTGATGTTAGAAAACCTTTCCTCCCTTATATTGCAAGATGGATAGTTAAAGAGGCAAAATTGCCA
AGCAATGAGATTGGAAAGGTTGCTGATGTTATTTATAAGTTATACAAAATCTTTAAAGAGTTGGATGCTACAATGGTTGA
AATCAATCCATTGGTTATAACTAAAGATGGAAACGTCTATGCCGCTGATGCTGTTCTTCACTTAGATGATGATGCAGCAT
TTAGACATAACTATGAAGAATTTGAAGAATATAAAAATAAAGAAAAATTACCATTTGCCTACGTTGAGTTGGATGGAGAT
GTGGCAGTTATAGGTAATGGAGCTGGTTTAACTTTGGCAAGTATGGATATTATAAATAACCTCGGCAGAAAGCCAGCTTG
CTTCTTAGATATTGGAGGAGGGGCTGATGCTGAAACTGTAAAATTGGCTTTGAGAAAGGTTTTAGAAAACAAAAATGTTA
AGGGAATATTTATTAATATTTTAGGAGGAATAACAAGGTGTGATGAAGTAGCAAAGGGAATTGTTGAAGTTTTAAAAGAA
CATCCAAATGTAAAGTTTGCTGTTAGAATGATGGGAACTAATGAAGAGATTGGAAGAAAAATATTGGAAGAACATGGAAT
ACCTTATGAGACATCAATGGAAGAAGCAGGAAGAAAATTGATTGAACAGCTATAA

Upstream 100 bases:

>100_bases
ATCACCGACAACATTAAACCTATAAATTTATCACCAAATTTTTTATATGATAATTTTAAAATTTTGCATTAAAAAGAAAT
TTATCATTTAAGGTGATAGG

Downstream 100 bases:

>100_bases
CAAAATAATTTTTATTTTATATTATTTCCCATAATTTTTTAATTTGTTTAATAAGGTGGCTTTTATGAACATCCCAATGA
TGGATTTAATAATGATTGTT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKLHEYEAKNIFKKYGIPVPESFLVSKEDDLNSINVDKEVVLKAQVLVGGRGKAGGILFASNKEEFIKKAEELFNKEVKG
EKVEKILVEEKLPIEKEYYVSIIIDRDAKKPLIIFSTEGGVDIEEVAEKNPEKIIKYHIDVRKPFLPYIARWIVKEAKLP
SNEIGKVADVIYKLYKIFKELDATMVEINPLVITKDGNVYAADAVLHLDDDAAFRHNYEEFEEYKNKEKLPFAYVELDGD
VAVIGNGAGLTLASMDIINNLGRKPACFLDIGGGADAETVKLALRKVLENKNVKGIFINILGGITRCDEVAKGIVEVLKE
HPNVKFAVRMMGTNEEIGRKILEEHGIPYETSMEEAGRKLIEQL

Sequences:

>Translated_364_residues
MKLHEYEAKNIFKKYGIPVPESFLVSKEDDLNSINVDKEVVLKAQVLVGGRGKAGGILFASNKEEFIKKAEELFNKEVKG
EKVEKILVEEKLPIEKEYYVSIIIDRDAKKPLIIFSTEGGVDIEEVAEKNPEKIIKYHIDVRKPFLPYIARWIVKEAKLP
SNEIGKVADVIYKLYKIFKELDATMVEINPLVITKDGNVYAADAVLHLDDDAAFRHNYEEFEEYKNKEKLPFAYVELDGD
VAVIGNGAGLTLASMDIINNLGRKPACFLDIGGGADAETVKLALRKVLENKNVKGIFINILGGITRCDEVAKGIVEVLKE
HPNVKFAVRMMGTNEEIGRKILEEHGIPYETSMEEAGRKLIEQL
>Mature_364_residues
MKLHEYEAKNIFKKYGIPVPESFLVSKEDDLNSINVDKEVVLKAQVLVGGRGKAGGILFASNKEEFIKKAEELFNKEVKG
EKVEKILVEEKLPIEKEYYVSIIIDRDAKKPLIIFSTEGGVDIEEVAEKNPEKIIKYHIDVRKPFLPYIARWIVKEAKLP
SNEIGKVADVIYKLYKIFKELDATMVEINPLVITKDGNVYAADAVLHLDDDAAFRHNYEEFEEYKNKEKLPFAYVELDGD
VAVIGNGAGLTLASMDIINNLGRKPACFLDIGGGADAETVKLALRKVLENKNVKGIFINILGGITRCDEVAKGIVEVLKE
HPNVKFAVRMMGTNEEIGRKILEEHGIPYETSMEEAGRKLIEQL

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=34.6153846153846, Blast_Score=221, Evalue=6e-58,
Organism=Homo sapiens, GI157779135, Length=384, Percent_Identity=35.4166666666667, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=35.8126721763085, Blast_Score=196, Evalue=4e-50,
Organism=Escherichia coli, GI1786948, Length=367, Percent_Identity=37.3297002724796, Blast_Score=225, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17539378, Length=396, Percent_Identity=35.6060606060606, Blast_Score=237, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17567829, Length=370, Percent_Identity=36.2162162162162, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=36.4556962025316, Blast_Score=231, Evalue=1e-61,
Organism=Drosophila melanogaster, GI21356231, Length=399, Percent_Identity=35.0877192982456, Blast_Score=224, Evalue=7e-59,
Organism=Drosophila melanogaster, GI161078106, Length=378, Percent_Identity=33.8624338624339, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24645208, Length=378, Percent_Identity=33.8624338624339, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI281361397, Length=379, Percent_Identity=34.0369393139842, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281361395, Length=379, Percent_Identity=34.0369393139842, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281363475, Length=374, Percent_Identity=27.807486631016, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281363473, Length=374, Percent_Identity=27.807486631016, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281363477, Length=374, Percent_Identity=27.807486631016, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_METJA (Q57663)

Other databases:

- EMBL:   L77117
- PIR:   C64326
- RefSeq:   NP_247178.1
- ProteinModelPortal:   Q57663
- SMR:   Q57663
- GeneID:   1451059
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0210
- NMPDR:   fig|243232.1.peg.215
- TIGR:   MJ0210
- HOGENOM:   HBG315432
- OMA:   IFINILG
- ProtClustDB:   CLSK876111
- BioCyc:   MJAN243232:MJ_0210-MONOMER
- BRENDA:   6.2.1.5
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 40908; Mature: 40908

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHEYEAKNIFKKYGIPVPESFLVSKEDDLNSINVDKEVVLKAQVLVGGRGKAGGILFA
CCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHEEEEEEEECCCCCCCCEEEE
SNKEEFIKKAEELFNKEVKGEKVEKILVEEKLPIEKEYYVSIIIDRDAKKPLIIFSTEGG
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCEEEEECCCC
VDIEEVAEKNPEKIIKYHIDVRKPFLPYIARWIVKEAKLPSNEIGKVADVIYKLYKIFKE
CCHHHHHCCCHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LDATMVEINPLVITKDGNVYAADAVLHLDDDAAFRHNYEEFEEYKNKEKLPFAYVELDGD
HCCEEEEECEEEEEECCCEEEEEEEEEECCCHHHHCCHHHHHHHCCCCCCCEEEEEECCC
VAVIGNGAGLTLASMDIINNLGRKPACFLDIGGGADAETVKLALRKVLENKNVKGIFINI
EEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
LGGITRCDEVAKGIVEVLKEHPNVKFAVRMMGTNEEIGRKILEEHGIPYETSMEEAGRKL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHH
IEQL
HHHC
>Mature Secondary Structure
MKLHEYEAKNIFKKYGIPVPESFLVSKEDDLNSINVDKEVVLKAQVLVGGRGKAGGILFA
CCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHEEEEEEEECCCCCCCCEEEE
SNKEEFIKKAEELFNKEVKGEKVEKILVEEKLPIEKEYYVSIIIDRDAKKPLIIFSTEGG
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCEEEEECCCC
VDIEEVAEKNPEKIIKYHIDVRKPFLPYIARWIVKEAKLPSNEIGKVADVIYKLYKIFKE
CCHHHHHCCCHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LDATMVEINPLVITKDGNVYAADAVLHLDDDAAFRHNYEEFEEYKNKEKLPFAYVELDGD
HCCEEEEECEEEEEECCCEEEEEEEEEECCCHHHHCCHHHHHHHCCCCCCCEEEEEECCC
VAVIGNGAGLTLASMDIINNLGRKPACFLDIGGGADAETVKLALRKVLENKNVKGIFINI
EEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
LGGITRCDEVAKGIVEVLKEHPNVKFAVRMMGTNEEIGRKILEEHGIPYETSMEEAGRKL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHH
IEQL
HHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087