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The map label for this gene is pelA

Identifier: 15668346

GI number: 15668346

Start: 176342

End: 177385

Strand: Direct

Name: pelA

Synonym: MJ0174

Alternate gene names: 15668346

Gene position: 176342-177385 (Clockwise)

Preceding gene: 15668345

Following gene: 15668348

Centisome position: 10.59

GC content: 31.32

Gene sequence:

>1044_bases
ATGAAAATTATAGAAGAAATTCCACAGAAAAATATTATTAAGCTTATGCCTGAAAACTTAGATGATTTATGGGTCTTATA
TAACATTATTGAAGAAGGAGATAAGATATTTGCAGTTACTGAGAGAAGAGTGCAGGATAAAGGAGACGTTATTAGAGCAG
ACAGAGGAGCCAAAAGAAAAATGTTTTTAGGAATTGAAGTAAAAAACGTAGAATTTGATGAAAACACGAAAAGAGTTAGA
ATTTTAGGAACTATAATTCATGGCCCAGACGATGTTCCCCTTGGCAGTCATCATACAATTGAAATTAAACCATTTGATGA
GCTTTCAATTGAAAAAAATTGGAAAAAATGGCAGATAGAGAGAATAAAGGAAGCTATTGAATCATCTAAAAGACCTAAGG
TTTTAGTTGTTGTTATGGATGATGAAGAAGCAGATATCTTTGAAGTTAGAGACTACAGCATAAAAGAAATTTGCTCAATA
AAATCTCACACTTCAAAAAAATTGGATTATAAAATTAACGAAGAGTTAAAAAAAGAGTATTATCATGAAATAGCTAAGGT
TTTGTCAGAGTATGATGTTGATAATATTTTGGTCGCAGGGCCAGGATTTGCAAAAAATAGCTTTTATAATTTTATTTCCT
CTCAATACCCAGAGCTTAAAAATAAAATAGTTGTGGAGAGCATATCAACAACCTCAAGAGCTGGATTAAATGAGGTTATT
AAAAGAGGAATTATTAATAGAATATATGCTGAATCAAGGGTTGCAAAAGAAACACAATTGATAGAAAAGCTTTTGGAAGA
GATTGCTAAAAAGGGATTGGCTGTTTATGGTATTGATGAAGTAAAAAAAGCTTTAGAATATTCAGCTATAGACACATTAT
TAGTTTCAGATAGCTTAGTAAGAAATCATGAGATAGAAAAAATAATAGATACTACTGAAGAGATGGGTGGGAAGGTAGTT
ATCGTTTCCTCTGAACATGATGCTGGAAAGCAATTAAAAGCCTTAGGAGGAATAGCCGGTTTATTAAGATTCCCTATTGA
ATAA

Upstream 100 bases:

>100_bases
AAAAGAAAATGCTTCAGAATTTATAGAAAAAAGAACAGTTAAAAAGAAATTTAAAATATACATCCTTGAAAATGGGGACT
TAGATGTTGGAGGGAGCTAA

Downstream 100 bases:

>100_bases
TTACTCTTGAATAGGACTTTCGCAGTTTATATATTGAATTTGGAATTTAGATGCCTAAAAGGCATCATTTTCCTTATAGA
GATTTATTCCTGCGAAAGTC

Product: cell division protein pelota PelA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKIIEEIPQKNIIKLMPENLDDLWVLYNIIEEGDKIFAVTERRVQDKGDVIRADRGAKRKMFLGIEVKNVEFDENTKRVR
ILGTIIHGPDDVPLGSHHTIEIKPFDELSIEKNWKKWQIERIKEAIESSKRPKVLVVVMDDEEADIFEVRDYSIKEICSI
KSHTSKKLDYKINEELKKEYYHEIAKVLSEYDVDNILVAGPGFAKNSFYNFISSQYPELKNKIVVESISTTSRAGLNEVI
KRGIINRIYAESRVAKETQLIEKLLEEIAKKGLAVYGIDEVKKALEYSAIDTLLVSDSLVRNHEIEKIIDTTEEMGGKVV
IVSSEHDAGKQLKALGGIAGLLRFPIE

Sequences:

>Translated_347_residues
MKIIEEIPQKNIIKLMPENLDDLWVLYNIIEEGDKIFAVTERRVQDKGDVIRADRGAKRKMFLGIEVKNVEFDENTKRVR
ILGTIIHGPDDVPLGSHHTIEIKPFDELSIEKNWKKWQIERIKEAIESSKRPKVLVVVMDDEEADIFEVRDYSIKEICSI
KSHTSKKLDYKINEELKKEYYHEIAKVLSEYDVDNILVAGPGFAKNSFYNFISSQYPELKNKIVVESISTTSRAGLNEVI
KRGIINRIYAESRVAKETQLIEKLLEEIAKKGLAVYGIDEVKKALEYSAIDTLLVSDSLVRNHEIEKIIDTTEEMGGKVV
IVSSEHDAGKQLKALGGIAGLLRFPIE
>Mature_347_residues
MKIIEEIPQKNIIKLMPENLDDLWVLYNIIEEGDKIFAVTERRVQDKGDVIRADRGAKRKMFLGIEVKNVEFDENTKRVR
ILGTIIHGPDDVPLGSHHTIEIKPFDELSIEKNWKKWQIERIKEAIESSKRPKVLVVVMDDEEADIFEVRDYSIKEICSI
KSHTSKKLDYKINEELKKEYYHEIAKVLSEYDVDNILVAGPGFAKNSFYNFISSQYPELKNKIVVESISTTSRAGLNEVI
KRGIINRIYAESRVAKETQLIEKLLEEIAKKGLAVYGIDEVKKALEYSAIDTLLVSDSLVRNHEIEKIIDTTEEMGGKVV
IVSSEHDAGKQLKALGGIAGLLRFPIE

Specific function: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has end

COG id: COG1537

COG function: function code R; Predicted RNA-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family. Pelota subfamily

Homologues:

Organism=Homo sapiens, GI31880783, Length=359, Percent_Identity=28.4122562674095, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17554648, Length=365, Percent_Identity=26.8493150684932, Blast_Score=118, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6324327, Length=381, Percent_Identity=25.4593175853018, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17136914, Length=367, Percent_Identity=26.4305177111717, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PELO_METJA (Q57638)

Other databases:

- EMBL:   L77117
- PIR:   G64321
- RefSeq:   NP_247142.1
- ProteinModelPortal:   Q57638
- SMR:   Q57638
- GeneID:   1451021
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0174
- NMPDR:   fig|243232.1.peg.179
- TIGR:   MJ0174
- HOGENOM:   HBG646058
- OMA:   MKLVRKD
- ProtClustDB:   CLSK876101
- BioCyc:   MJAN243232:MJ_0174-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01853
- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR004405
- PANTHER:   PTHR10853
- TIGRFAMs:   TIGR00111

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3

EC number: NA

Molecular weight: Translated: 39624; Mature: 39624

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIEEIPQKNIIKLMPENLDDLWVLYNIIEEGDKIFAVTERRVQDKGDVIRADRGAKRK
CCCHHHCCCCHHHHHCCCCCHHHHHHHHHHHCCCEEEEEHHHHHHCCCCEEECCCCCCCE
MFLGIEVKNVEFDENTKRVRILGTIIHGPDDVPLGSHHTIEIKPFDELSIEKNWKKWQIE
EEEEEEEECCEECCCCCEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHH
RIKEAIESSKRPKVLVVVMDDEEADIFEVRDYSIKEICSIKSHTSKKLDYKINEELKKEY
HHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
YHEIAKVLSEYDVDNILVAGPGFAKNSFYNFISSQYPELKNKIVVESISTTSRAGLNEVI
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCHHHHCCEEEEECCCHHHCCHHHHH
KRGIINRIYAESRVAKETQLIEKLLEEIAKKGLAVYGIDEVKKALEYSAIDTLLVSDSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
RNHEIEKIIDTTEEMGGKVVIVSSEHDAGKQLKALGGIAGLLRFPIE
HHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIIEEIPQKNIIKLMPENLDDLWVLYNIIEEGDKIFAVTERRVQDKGDVIRADRGAKRK
CCCHHHCCCCHHHHHCCCCCHHHHHHHHHHHCCCEEEEEHHHHHHCCCCEEECCCCCCCE
MFLGIEVKNVEFDENTKRVRILGTIIHGPDDVPLGSHHTIEIKPFDELSIEKNWKKWQIE
EEEEEEEECCEECCCCCEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHH
RIKEAIESSKRPKVLVVVMDDEEADIFEVRDYSIKEICSIKSHTSKKLDYKINEELKKEY
HHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
YHEIAKVLSEYDVDNILVAGPGFAKNSFYNFISSQYPELKNKIVVESISTTSRAGLNEVI
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCHHHHCCEEEEECCCHHHCCHHHHH
KRGIINRIYAESRVAKETQLIEKLLEEIAKKGLAVYGIDEVKKALEYSAIDTLLVSDSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
RNHEIEKIIDTTEEMGGKVVIVSSEHDAGKQLKALGGIAGLLRFPIE
HHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087