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The map label for this gene is moaB

Identifier: 15668339

GI number: 15668339

Start: 170193

End: 170684

Strand: Reverse

Name: moaB

Synonym: MJ0167

Alternate gene names: 15668339

Gene position: 170684-170193 (Counterclockwise)

Preceding gene: 15668340

Following gene: 15668338

Centisome position: 10.25

GC content: 29.88

Gene sequence:

>492_bases
ATGCACAAAAGAATAAAAAATATAAAATATGCGGTAGTTACTGTAAGTGATAGTAGATATAATGATTTAATTAAGGGAAA
AGAAGTAGATGATAAATCTGGAAAATTATTAAAAAAAGAACTAAACGCTAAAGTATATACAATAATCCCCGACAACAAAA
ATATGATTAAAGGAATAGTTGAGCATATAGTTGAATTTTTTGATGTAGATTGTATTGTTTTCACAGGAGGAACTGGAATA
GCTGAGAGAGATGTCACTGTAGAAGCATTGAAAGAAATTATTGAAAAAGAGTTAGATGGCTTTAAAATTATTTTTCAAAA
ACTAAGTTATGAGGAAGTTGGATTCTCAGCCATGCTATCAAGAGCTATGGCTGGAATTTATAAAGGAAAAATCATATATG
CCCTCCCAGGCTCAGTAAATGCATGTAGAACAGCATTAAAGATAATTAAAGAAGAAACAGGACATATATTAGGACATTTA
AGAGAGGGATAA

Upstream 100 bases:

>100_bases
TTTTTATTATTAATATTTTACTTCCTTCCAAAACTTTAGAATTCTTTTGTTATTTTAATTTATATTCATTAATTTATATA
TTTATTTAAACGGTGGAAAT

Downstream 100 bases:

>100_bases
GATGAAATTTTTGTTAATAGCATCAAATAAAGATTTAGCAAGTAAAAACATAGCTAATCATATAAAAGAGTATTTTGATG
TTTTTGAAACTGATAAGGAG

Product: molybdenum cofactor biosynthesis protein MoaB

Products: NA

Alternate protein names: MPT adenylyltransferase

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MHKRIKNIKYAVVTVSDSRYNDLIKGKEVDDKSGKLLKKELNAKVYTIIPDNKNMIKGIVEHIVEFFDVDCIVFTGGTGI
AERDVTVEALKEIIEKELDGFKIIFQKLSYEEVGFSAMLSRAMAGIYKGKIIYALPGSVNACRTALKIIKEETGHILGHL
REG

Sequences:

>Translated_163_residues
MHKRIKNIKYAVVTVSDSRYNDLIKGKEVDDKSGKLLKKELNAKVYTIIPDNKNMIKGIVEHIVEFFDVDCIVFTGGTGI
AERDVTVEALKEIIEKELDGFKIIFQKLSYEEVGFSAMLSRAMAGIYKGKIIYALPGSVNACRTALKIIKEETGHILGHL
REG
>Mature_163_residues
MHKRIKNIKYAVVTVSDSRYNDLIKGKEVDDKSGKLLKKELNAKVYTIIPDNKNMIKGIVEHIVEFFDVDCIVFTGGTGI
AERDVTVEALKEIIEKELDGFKIIFQKLSYEEVGFSAMLSRAMAGIYKGKIIYALPGSVNACRTALKIIKEETGHILGHL
REG

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family

Homologues:

Organism=Homo sapiens, GI66932975, Length=169, Percent_Identity=33.7278106508876, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI10880983, Length=169, Percent_Identity=33.7278106508876, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1787000, Length=146, Percent_Identity=36.986301369863, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1786190, Length=162, Percent_Identity=26.5432098765432, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=157, Percent_Identity=31.8471337579618, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136978, Length=157, Percent_Identity=30.5732484076433, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24638841, Length=157, Percent_Identity=30.5732484076433, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAB_METJA (Q57631)

Other databases:

- EMBL:   L77117
- PIR:   H64320
- RefSeq:   NP_247135.1
- ProteinModelPortal:   Q57631
- SMR:   Q57631
- GeneID:   1451014
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0167
- NMPDR:   fig|243232.1.peg.172
- TIGR:   MJ0167
- HOGENOM:   HBG460560
- OMA:   HIIGHIK
- ProtClustDB:   CLSK876097
- BioCyc:   MJAN243232:MJ_0167-MONOMER
- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006443
- SMART:   SM00852
- TIGRFAMs:   TIGR00177

Pfam domain/function: PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 18248; Mature: 18248

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKRIKNIKYAVVTVSDSRYNDLIKGKEVDDKSGKLLKKELNAKVYTIIPDNKNMIKGIV
CCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHH
EHIVEFFDVDCIVFTGGTGIAERDVTVEALKEIIEKELDGFKIIFQKLSYEEVGFSAMLS
HHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHH
RAMAGIYKGKIIYALPGSVNACRTALKIIKEETGHILGHLREG
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHKRIKNIKYAVVTVSDSRYNDLIKGKEVDDKSGKLLKKELNAKVYTIIPDNKNMIKGIV
CCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHH
EHIVEFFDVDCIVFTGGTGIAERDVTVEALKEIIEKELDGFKIIFQKLSYEEVGFSAMLS
HHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHH
RAMAGIYKGKIIYALPGSVNACRTALKIIKEETGHILGHLREG
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087