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The map label for this gene is ilvH

Identifier: 15668333

GI number: 15668333

Start: 164653

End: 165171

Strand: Reverse

Name: ilvH

Synonym: MJ0161

Alternate gene names: 15668333

Gene position: 165171-164653 (Counterclockwise)

Preceding gene: 15668335

Following gene: 15668332

Centisome position: 9.92

GC content: 32.37

Gene sequence:

>519_bases
TTGGTGAATATAATGGAACATAGGCATGTCATCTCCGCGTTAGTTTTAAATAAACCAGGAGTATTGCAGAGAATTTCAGG
GTTATTTACAAGGAGAGGGTTTAATATTTCAAGTATTACAGTCGGAATAACAGAGAATCCACAAATTTCAAGAGTTACGA
TAGTTGTTAATGGAGATGATAAGATATTAGAGCAGGTTATCAAACAACTCAACAAATTAATTGATGTTATAAAGGTTAGT
GAGTTAGAGGAAAAGAAATCCGTTCAGAGAGAGCTCTGTTTAATAAAGATTTATGCACCAACAGAGAGTGCAAAATCACA
AGTTATTCAATATACAAGCATATTTAGAGGAAATGTTGTAGATTTAAGTCCAGAATCTTTAATTGTAGAGATAACTGGTA
GTGAAGATAAAATAAACGCATTTATTGACTTAGTTAAACCATTAGGAATTAAAGAAATGGCAAGAACTGGAATAACTGCC
TTAGCAAGGGGACCAAAAATCTTAAAACCAAAAAGCTAA

Upstream 100 bases:

>100_bases
CAAAAATATGCAAATCAAAAATTTCAGGTATCATAATTATTATATGGTGAGTTCTACTAAATATCTATTTTATTATTTTT
AAATCTTACTATAAAAAGGA

Downstream 100 bases:

>100_bases
GTTTTAAAAAGACCAAAATAAGGTGGAAACATGAACGATGACGTTAAAATGAAGTGTGGTTTGGAAATGCACGTGAAAAT
TTAATAAAGTTTCATCAAAA

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MVNIMEHRHVISALVLNKPGVLQRISGLFTRRGFNISSITVGITENPQISRVTIVVNGDDKILEQVIKQLNKLIDVIKVS
ELEEKKSVQRELCLIKIYAPTESAKSQVIQYTSIFRGNVVDLSPESLIVEITGSEDKINAFIDLVKPLGIKEMARTGITA
LARGPKILKPKS

Sequences:

>Translated_172_residues
MVNIMEHRHVISALVLNKPGVLQRISGLFTRRGFNISSITVGITENPQISRVTIVVNGDDKILEQVIKQLNKLIDVIKVS
ELEEKKSVQRELCLIKIYAPTESAKSQVIQYTSIFRGNVVDLSPESLIVEITGSEDKINAFIDLVKPLGIKEMARTGITA
LARGPKILKPKS
>Mature_172_residues
MVNIMEHRHVISALVLNKPGVLQRISGLFTRRGFNISSITVGITENPQISRVTIVVNGDDKILEQVIKQLNKLIDVIKVS
ELEEKKSVQRELCLIKIYAPTESAKSQVIQYTSIFRGNVVDLSPESLIVEITGSEDKINAFIDLVKPLGIKEMARTGITA
LARGPKILKPKS

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain

Homologues:

Organism=Escherichia coli, GI1786266, Length=163, Percent_Identity=42.9447852760736, Blast_Score=143, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6319837, Length=206, Percent_Identity=32.5242718446602, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ILVH_METJA (Q57625)

Other databases:

- EMBL:   L77117
- PIR:   B64320
- RefSeq:   NP_247129.1
- ProteinModelPortal:   Q57625
- SMR:   Q57625
- GeneID:   1451008
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0161
- NMPDR:   fig|243232.1.peg.166
- TIGR:   MJ0161
- HOGENOM:   HBG335310
- OMA:   IERELAM
- ProtClustDB:   PRK11895
- BioCyc:   MJAN243232:MJ_0161-MONOMER
- BRENDA:   2.2.1.6
- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912
- TIGRFAMs:   TIGR00119

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C

EC number: =2.2.1.6

Molecular weight: Translated: 19058; Mature: 19058

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNIMEHRHVISALVLNKPGVLQRISGLFTRRGFNISSITVGITENPQISRVTIVVNGDD
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEECCCH
KILEQVIKQLNKLIDVIKVSELEEKKSVQRELCLIKIYAPTESAKSQVIQYTSIFRGNVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHCCCEE
DLSPESLIVEITGSEDKINAFIDLVKPLGIKEMARTGITALARGPKILKPKS
EECCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVNIMEHRHVISALVLNKPGVLQRISGLFTRRGFNISSITVGITENPQISRVTIVVNGDD
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEECCCH
KILEQVIKQLNKLIDVIKVSELEEKKSVQRELCLIKIYAPTESAKSQVIQYTSIFRGNVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHCCCEE
DLSPESLIVEITGSEDKINAFIDLVKPLGIKEMARTGITALARGPKILKPKS
EECCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087