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The map label for this gene is 15668278

Identifier: 15668278

GI number: 15668278

Start: 102721

End: 104298

Strand: Direct

Name: 15668278

Synonym: MJ0107

Alternate gene names: NA

Gene position: 102721-104298 (Clockwise)

Preceding gene: 15668275

Following gene: 15668279

Centisome position: 6.17

GC content: 30.74

Gene sequence:

>1578_bases
TTGAGGGAGATTATGAAAATTCTAATAATCACTGGAAAATTAGCTGAAAGGAAAGTTAAAGATGCTGTGAAAAAATATGA
TTTTATAGATGTGCATGTAGCAAATATCTCTGTAGCTGCTTTTTTAACACCTAATTTAATAATTAAAGAAATTAAAAAAT
TAGAAAACAAATTAGGAAAAAAATTAAAAGATATTTATGATTTTGTTTTAGTAACTGGGTTGATAAGACATGATTTAAAG
AATGTTGAGGAAGAAACCGGAATAAAATGCTTTAAATCTACAAGAGAAGCTTCTGATATTCCAATATTGATTGAAAATCT
GGATAAGATAAAACTATCAACTAAAGAGTATGCCGATTTGCAGTTATTAGAAATTATTAGAAAGAAATGTGAGGAGGAGA
TTAAGAAAGCAGAGGAGCAGGAATTAGGAGAAGGAGATATAAAGATAGGCAAATTAAAAGTTGGAGATAAATTCCCAATG
AGAGTTTTGGGAGAGATAGTCCATGCCCCATGGCTAAAAGAGAAAGAGTTGGAGGAGAAAATAATATATTACTTAGAAAG
TGGGGCTGATATGATTGATTTGGGAATGGTTAGCAATGAAAATAATGCAGATAAAATTAAAGATATGCTAAAGATAGCGA
GAGATTTAACTGACAATCCAATTAGTGTAGATACATTAAACACAAAAGAATTAATTGAGGCAATAAATTTAGGGGCAGAT
ATGATTTTGAGTGTTGATGCTGGGAATTTAGATGAGCTAATTCCATATTTAAAAGATTCAGAAACGGCAGTTGTTGTTCT
GCCAACAAATTATAAAACAAACTATGTCCCAGAGACTATTGAAGGCAAAATTAAATCCTTAGAGGAGAATATAAAAAAGC
TAATAGATGCTGGAATTGAAAAAATAGTTGCTGACCCAATATTAGAGCCAATAAACAATGCCGGATGCAGTTTTATAGAG
AGCGTTATTGCATGTAGAGAATTTAAAAAAAGAAATAAATTGCCACTATTTTTTGGTGTTGGAAATGTTACAGAGCTTTT
TGATGCTGATAGTAATGGAGTCAATGCTTTGTTAGCAGCTATTGGGGCTGAGATTGGAGCTAATATATTATTTACACCAG
AGGCAAGTGCTAAGTGTAAATTTTCAATAAAAGAGTTAAAGATTGCCTCAAAGATGATGTTTTTGGCTAAAAAAAGGAAC
TCTCTGCCAAAGGATATTGGCTACAATTTGATAAATTATAAGGATAAAAGATTTGAGGAGGAAATAACCTTCAATAGTTA
CAATATCCCAATAATTAAAGCTGAAGAAGATGAGAGGCAGATATTGGATGAAGGAAGTTTTAAAATAGAAATTGATAGGA
AGAACAAAGAGATAGTAGCAATATACTTTAATAAAAGAAGAGAACCAGTTTTAATAATTAGAGGAAAGAAACCAAAAGAA
ATTTATGAAACCGCGATAAGATTAAATTTAATAAAAAAGTTAGACCATGCATCTTATTTTGGTAGAGAGTTAGCTAAGGC
AGAGATTGCTTTAAGGATAGGTAAAAAATACAATCAGGACTTTGATTTGTTCCTATAA

Upstream 100 bases:

>100_bases
GTATTATATATTAAAAGGCATTTAGATGCCCTTAAGCATAAATTTTCTTTAAAAAATTTATTTCTACGAAAGTCCTAAAT
CTTATATTGACTATGAAAGT

Downstream 100 bases:

>100_bases
TGAATTTTGGTGGGAATGATGAGAAAAACTAAAATTTTAGTCACTTTAGGACCATCCTTAGAAAATAAATTAGATAAAGC
AATAAATTTGATAGATGGAG

Product: dihydropteroate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MREIMKILIITGKLAERKVKDAVKKYDFIDVHVANISVAAFLTPNLIIKEIKKLENKLGKKLKDIYDFVLVTGLIRHDLK
NVEEETGIKCFKSTREASDIPILIENLDKIKLSTKEYADLQLLEIIRKKCEEEIKKAEEQELGEGDIKIGKLKVGDKFPM
RVLGEIVHAPWLKEKELEEKIIYYLESGADMIDLGMVSNENNADKIKDMLKIARDLTDNPISVDTLNTKELIEAINLGAD
MILSVDAGNLDELIPYLKDSETAVVVLPTNYKTNYVPETIEGKIKSLEENIKKLIDAGIEKIVADPILEPINNAGCSFIE
SVIACREFKKRNKLPLFFGVGNVTELFDADSNGVNALLAAIGAEIGANILFTPEASAKCKFSIKELKIASKMMFLAKKRN
SLPKDIGYNLINYKDKRFEEEITFNSYNIPIIKAEEDERQILDEGSFKIEIDRKNKEIVAIYFNKRREPVLIIRGKKPKE
IYETAIRLNLIKKLDHASYFGRELAKAEIALRIGKKYNQDFDLFL

Sequences:

>Translated_525_residues
MREIMKILIITGKLAERKVKDAVKKYDFIDVHVANISVAAFLTPNLIIKEIKKLENKLGKKLKDIYDFVLVTGLIRHDLK
NVEEETGIKCFKSTREASDIPILIENLDKIKLSTKEYADLQLLEIIRKKCEEEIKKAEEQELGEGDIKIGKLKVGDKFPM
RVLGEIVHAPWLKEKELEEKIIYYLESGADMIDLGMVSNENNADKIKDMLKIARDLTDNPISVDTLNTKELIEAINLGAD
MILSVDAGNLDELIPYLKDSETAVVVLPTNYKTNYVPETIEGKIKSLEENIKKLIDAGIEKIVADPILEPINNAGCSFIE
SVIACREFKKRNKLPLFFGVGNVTELFDADSNGVNALLAAIGAEIGANILFTPEASAKCKFSIKELKIASKMMFLAKKRN
SLPKDIGYNLINYKDKRFEEEITFNSYNIPIIKAEEDERQILDEGSFKIEIDRKNKEIVAIYFNKRREPVLIIRGKKPKE
IYETAIRLNLIKKLDHASYFGRELAKAEIALRIGKKYNQDFDLFL
>Mature_525_residues
MREIMKILIITGKLAERKVKDAVKKYDFIDVHVANISVAAFLTPNLIIKEIKKLENKLGKKLKDIYDFVLVTGLIRHDLK
NVEEETGIKCFKSTREASDIPILIENLDKIKLSTKEYADLQLLEIIRKKCEEEIKKAEEQELGEGDIKIGKLKVGDKFPM
RVLGEIVHAPWLKEKELEEKIIYYLESGADMIDLGMVSNENNADKIKDMLKIARDLTDNPISVDTLNTKELIEAINLGAD
MILSVDAGNLDELIPYLKDSETAVVVLPTNYKTNYVPETIEGKIKSLEENIKKLIDAGIEKIVADPILEPINNAGCSFIE
SVIACREFKKRNKLPLFFGVGNVTELFDADSNGVNALLAAIGAEIGANILFTPEASAKCKFSIKELKIASKMMFLAKKRN
SLPKDIGYNLINYKDKRFEEEITFNSYNIPIIKAEEDERQILDEGSFKIEIDRKNKEIVAIYFNKRREPVLIIRGKKPKE
IYETAIRLNLIKKLDHASYFGRELAKAEIALRIGKKYNQDFDLFL

Specific function: Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate

COG id: COG0294

COG function: function code H; Dihydropteroate synthase and related enzymes

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y107_METJA (Q57571)

Other databases:

- EMBL:   L77117
- PIR:   C64313
- RefSeq:   NP_247071.1
- ProteinModelPortal:   Q57571
- GeneID:   1450948
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0107
- NMPDR:   fig|243232.1.peg.108
- TIGR:   MJ0107
- HOGENOM:   HBG553769
- OMA:   DEPLDWG
- ProtClustDB:   CLSK876073
- BioCyc:   MJAN243232:MJ_0107-MONOMER
- InterPro:   IPR005236
- InterPro:   IPR011005
- InterPro:   IPR000489
- Gene3D:   G3DSA:3.20.20.20
- TIGRFAMs:   TIGR00284

Pfam domain/function: PF00809 Pterin_bind; SSF51717 DHP_synth_like

EC number: NA

Molecular weight: Translated: 59645; Mature: 59645

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50972 PTERIN_BINDING; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc08b2e4)-; HASH(0xba86520)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIMKILIITGKLAERKVKDAVKKYDFIDVHVANISVAAFLTPNLIIKEIKKLENKLGK
CHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEEEEEEEEEEHHCHHHHHHHHHHHHHHHHH
KLKDIYDFVLVTGLIRHDLKNVEEETGIKCFKSTREASDIPILIENLDKIKLSTKEYADL
HHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHCCCCCCCCEEECCCCHHEECCHHHHHH
QLLEIIRKKCEEEIKKAEEQELGEGDIKIGKLKVGDKFPMRVLGEIVHAPWLKEKELEEK
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHH
IIYYLESGADMIDLGMVSNENNADKIKDMLKIARDLTDNPISVDTLNTKELIEAINLGAD
HHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCC
MILSVDAGNLDELIPYLKDSETAVVVLPTNYKTNYVPETIEGKIKSLEENIKKLIDAGIE
EEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KIVADPILEPINNAGCSFIESVIACREFKKRNKLPLFFGVGNVTELFDADSNGVNALLAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCHHHHHHH
IGAEIGANILFTPEASAKCKFSIKELKIASKMMFLAKKRNSLPKDIGYNLINYKDKRFEE
HHHHHCCCEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCHHHHHH
EITFNSYNIPIIKAEEDERQILDEGSFKIEIDRKNKEIVAIYFNKRREPVLIIRGKKPKE
HHCCCCCCCEEEECCCHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCEEEEECCCCHH
IYETAIRLNLIKKLDHASYFGRELAKAEIALRIGKKYNQDFDLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure
MREIMKILIITGKLAERKVKDAVKKYDFIDVHVANISVAAFLTPNLIIKEIKKLENKLGK
CHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEEEEEEEEEEHHCHHHHHHHHHHHHHHHHH
KLKDIYDFVLVTGLIRHDLKNVEEETGIKCFKSTREASDIPILIENLDKIKLSTKEYADL
HHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHCCCCCCCCEEECCCCHHEECCHHHHHH
QLLEIIRKKCEEEIKKAEEQELGEGDIKIGKLKVGDKFPMRVLGEIVHAPWLKEKELEEK
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHH
IIYYLESGADMIDLGMVSNENNADKIKDMLKIARDLTDNPISVDTLNTKELIEAINLGAD
HHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCC
MILSVDAGNLDELIPYLKDSETAVVVLPTNYKTNYVPETIEGKIKSLEENIKKLIDAGIE
EEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KIVADPILEPINNAGCSFIESVIACREFKKRNKLPLFFGVGNVTELFDADSNGVNALLAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCHHHHHHH
IGAEIGANILFTPEASAKCKFSIKELKIASKMMFLAKKRNSLPKDIGYNLINYKDKRFEE
HHHHHCCCEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCHHHHHH
EITFNSYNIPIIKAEEDERQILDEGSFKIEIDRKNKEIVAIYFNKRREPVLIIRGKKPKE
HHCCCCCCCEEEECCCHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCEEEEECCCCHH
IYETAIRLNLIKKLDHASYFGRELAKAEIALRIGKKYNQDFDLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087