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The map label for this gene is btuC [C]

Identifier: 15668258

GI number: 15668258

Start: 81930

End: 82979

Strand: Direct

Name: btuC [C]

Synonym: MJ0087

Alternate gene names: 15668258

Gene position: 81930-82979 (Clockwise)

Preceding gene: 15668257

Following gene: 15668259

Centisome position: 4.92

GC content: 36.38

Gene sequence:

>1050_bases
ATGGACATCCCACAGAAATATAAGTTATATACAAAAAAGAAGATAATTTTTGGGATTATTTTACTTATAACTTTATTTTT
AAGCTCAATTTATGCCTTATGCGTAGGAGACTATAAATTAACTGTTAATCAGGTTGTAAATGCCTTAATGGGTTATGGAA
AAGATGATATAAACTTAGTTATTTGGAATATCAGACTGCCAAGGATATTTGCCGCAATAATATCTGGAATGTCTTTAGCT
GTAGCTGGGGCAGTTATGCAGTGCATTTTAAGAAACCCATTGGCAAGCCCATTTACGATGGGAATTTCACATGGAGCAAT
GTTTGGTGCATGTTTTGCCATAATCATGTTTGGTTTTGGAGGGGCTGAGAGCACTGGAAGAATATTTATAAACAACCCAT
ACATGATAACAATCTTTGCATTCTTAGGGGCTTTGATTGGTGTTGTTGTAATCTTATTACTTGCTAAGTTGAGGGGATTA
ACTCCAGAGGCCATGATTTTAGCTGGAGTTGCTATGAGCTCTCTATTTACAGCTGGAACTATGCTCATCCAATACTTTGC
AGATGATTTGCAGTTGGCGGCAATGGTTTATTGGACTTTTGGAGACTTGGGAAGAGCTATATGGACAGAGATTTATATCA
TGGCTGCAGTTATGATTCCCTCTTTAATATATTTCATGTATAAAAGGTGGGATTACAATGCCTTAGAGGCTGGAGAAGAG
ACAGCTAAATCCTTAGGAGTTAATACAGAGAGGACAAGATTGATTGGCATGCTTGTAGCTTCATTATTAACATCAGTAAA
TGTAGCATTCTTGGGAATAATTGGATTTGTTGGTTTAATCTGCCCACATATAGTTAGGATTTGCATTGGAGGAGATTACA
GGTTTTTAATTCCAATCTCTGCATTGTTTGGGGCTGTTTTATTGCTTATTGCTGATACGTTTGCAAGGACAATAATTGCT
CCGATAGTGTTGCCAGTTGGGATTTTAACATCTTTCTTAGGAGCTCCGATGTTTCTTTACTTGCTGTTAAAGATGTATAA
AAGAGTATAA

Upstream 100 bases:

>100_bases
AGTCAGCGAATCCTTCGGATTCGCTTCGATTTAAAGATAATTCACCAGCAAAGATGATTGTTGCTAAAAAGCTTTAAAAT
AATTCAAAAAATGTGATAGT

Downstream 100 bases:

>100_bases
TAATAGTATATTATTAGTTTGCCAAATATTTGGGGTGGAATGTTGGAAAAAACTGTAAAAATAACCTTTATCTTCGAATC
AGAAAAAAGGTTGAACTGGG

Product: hemin permease HemU

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MDIPQKYKLYTKKKIIFGIILLITLFLSSIYALCVGDYKLTVNQVVNALMGYGKDDINLVIWNIRLPRIFAAIISGMSLA
VAGAVMQCILRNPLASPFTMGISHGAMFGACFAIIMFGFGGAESTGRIFINNPYMITIFAFLGALIGVVVILLLAKLRGL
TPEAMILAGVAMSSLFTAGTMLIQYFADDLQLAAMVYWTFGDLGRAIWTEIYIMAAVMIPSLIYFMYKRWDYNALEAGEE
TAKSLGVNTERTRLIGMLVASLLTSVNVAFLGIIGFVGLICPHIVRICIGGDYRFLIPISALFGAVLLLIADTFARTIIA
PIVLPVGILTSFLGAPMFLYLLLKMYKRV

Sequences:

>Translated_349_residues
MDIPQKYKLYTKKKIIFGIILLITLFLSSIYALCVGDYKLTVNQVVNALMGYGKDDINLVIWNIRLPRIFAAIISGMSLA
VAGAVMQCILRNPLASPFTMGISHGAMFGACFAIIMFGFGGAESTGRIFINNPYMITIFAFLGALIGVVVILLLAKLRGL
TPEAMILAGVAMSSLFTAGTMLIQYFADDLQLAAMVYWTFGDLGRAIWTEIYIMAAVMIPSLIYFMYKRWDYNALEAGEE
TAKSLGVNTERTRLIGMLVASLLTSVNVAFLGIIGFVGLICPHIVRICIGGDYRFLIPISALFGAVLLLIADTFARTIIA
PIVLPVGILTSFLGAPMFLYLLLKMYKRV
>Mature_349_residues
MDIPQKYKLYTKKKIIFGIILLITLFLSSIYALCVGDYKLTVNQVVNALMGYGKDDINLVIWNIRLPRIFAAIISGMSLA
VAGAVMQCILRNPLASPFTMGISHGAMFGACFAIIMFGFGGAESTGRIFINNPYMITIFAFLGALIGVVVILLLAKLRGL
TPEAMILAGVAMSSLFTAGTMLIQYFADDLQLAAMVYWTFGDLGRAIWTEIYIMAAVMIPSLIYFMYKRWDYNALEAGEE
TAKSLGVNTERTRLIGMLVASLLTSVNVAFLGIIGFVGLICPHIVRICIGGDYRFLIPISALFGAVLLLIADTFARTIIA
PIVLPVGILTSFLGAPMFLYLLLKMYKRV

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily

Homologues:

Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=37.2822299651568, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790740, Length=288, Percent_Identity=36.8055555555556, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786347, Length=297, Percent_Identity=34.6801346801347, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1786805, Length=319, Percent_Identity=30.7210031347962, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786804, Length=342, Percent_Identity=32.4561403508772, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790741, Length=329, Percent_Identity=29.483282674772, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y087_METJA (Q57552)

Other databases:

- EMBL:   L77117
- PIR:   G64310
- RefSeq:   NP_247051.1
- ProteinModelPortal:   Q57552
- SMR:   Q57552
- GeneID:   1450926
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0087
- NMPDR:   fig|243232.1.peg.88
- TIGR:   MJ0087
- HOGENOM:   HBG700016
- OMA:   LASPFTM
- ProtClustDB:   CLSK876062
- BioCyc:   MJAN243232:MJ_0087-MONOMER
- InterPro:   IPR000522

Pfam domain/function: PF01032 FecCD

EC number: NA

Molecular weight: Translated: 38202; Mature: 38202

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbdcbcfc)-; HASH(0xb20b618)-; HASH(0xb14e804)-; HASH(0x406ca464)-; HASH(0xb164700)-; HASH(0x406c8d6c)-; HASH(0x406c9a80)-; HASH(0xb64d408)-; HASH(0x406ca83c)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIPQKYKLYTKKKIIFGIILLITLFLSSIYALCVGDYKLTVNQVVNALMGYGKDDINLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEE
IWNIRLPRIFAAIISGMSLAVAGAVMQCILRNPLASPFTMGISHGAMFGACFAIIMFGFG
EEECHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GAESTGRIFINNPYMITIFAFLGALIGVVVILLLAKLRGLTPEAMILAGVAMSSLFTAGT
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
MLIQYFADDLQLAAMVYWTFGDLGRAIWTEIYIMAAVMIPSLIYFMYKRWDYNALEAGEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TAKSLGVNTERTRLIGMLVASLLTSVNVAFLGIIGFVGLICPHIVRICIGGDYRFLIPIS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
ALFGAVLLLIADTFARTIIAPIVLPVGILTSFLGAPMFLYLLLKMYKRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDIPQKYKLYTKKKIIFGIILLITLFLSSIYALCVGDYKLTVNQVVNALMGYGKDDINLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEE
IWNIRLPRIFAAIISGMSLAVAGAVMQCILRNPLASPFTMGISHGAMFGACFAIIMFGFG
EEECHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GAESTGRIFINNPYMITIFAFLGALIGVVVILLLAKLRGLTPEAMILAGVAMSSLFTAGT
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
MLIQYFADDLQLAAMVYWTFGDLGRAIWTEIYIMAAVMIPSLIYFMYKRWDYNALEAGEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TAKSLGVNTERTRLIGMLVASLLTSVNVAFLGIIGFVGLICPHIVRICIGGDYRFLIPIS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
ALFGAVLLLIADTFARTIIAPIVLPVGILTSFLGAPMFLYLLLKMYKRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087