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The map label for this gene is frhG

Identifier: 15668201

GI number: 15668201

Start: 31799

End: 32491

Strand: Direct

Name: frhG

Synonym: MJ0031

Alternate gene names: 15668201

Gene position: 31799-32491 (Clockwise)

Preceding gene: 15668200

Following gene: 15668202

Centisome position: 1.91

GC content: 38.96

Gene sequence:

>693_bases
GTGATTAAAGTGGTTAAAGTTGCTCATGTTCAATTATGCAGTTGTTGCGGTTGCTTAGTGTCTTTAGCAGACACATATGA
AAAGCTTTTAGATGTTTTGAATTCAATTGAGTTGGTTTATTGTCAAACTTTAGCAGATGCAAGAGAAATTCCTGAATGCG
ATATTGCTTTAGTTGAAGGCTCTGTCTGTTTAGATGACCACCACTCATTGGAAGTAGCTCAAGAAGTTAGAAAGAAGGCA
AAAATTGTTGTTGCCTTAGGAGCATGTGCTGCAACAGGAGGGGTTACAAGATACTGTAAAGGAAACCAATTATCAAAGCC
TGTTCATAGCTCATTCTCTCCATTAACTGAAGTCATTAAAGTAGATTTAGCAATTCCTGGATGCCCACCTTCACCAGAGG
CAATCGTGGGAGTAATTACAGCAGCATTAAACGGAGATATGGAGTATCTACAACCTTATGCTGAATTGGCAGAAAAAGGA
AGTGAAGCTTGCGGATGTGATGTTATCTACAAAGTTGTCAATAAATCCCTTTGCATGGGATGTGGAACTTGTGCTGCTGC
TTGTCCAACAAGAGCTATAGAAATGTTAGATGGAAGGCCAAATGTCTTGAAAGAACTCTGTATTAAGTGTGGAGCTTGCT
CTGTCCAGTGTCCAAGAATTAGATTCCCAGAGTTAATTGAGAAAATAGAATAA

Upstream 100 bases:

>100_bases
GCCAAGTATATTTCTGAGCCAGATGTTTATATTGGGTTGAGTGAAGAGGTTGAAAAAGCCGTTGATAAGGCAGTTGAGAT
AATTCTTAGAGAGTTGAGAG

Downstream 100 bases:

>100_bases
AATAATATAATATAATTTTTTGAGGTGGAATAGGATGAATCCTTTTGGTAGCTATAAAAAAGTTGTCTCAGCAAGGAGTA
CATTAAAAGAAGTTTTAAAG

Product: coenzyme F420-reducing hydrogenase subunit gamma

Products: NA

Alternate protein names: 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma; FRH

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIKVVKVAHVQLCSCCGCLVSLADTYEKLLDVLNSIELVYCQTLADAREIPECDIALVEGSVCLDDHHSLEVAQEVRKKA
KIVVALGACAATGGVTRYCKGNQLSKPVHSSFSPLTEVIKVDLAIPGCPPSPEAIVGVITAALNGDMEYLQPYAELAEKG
SEACGCDVIYKVVNKSLCMGCGTCAAACPTRAIEMLDGRPNVLKELCIKCGACSVQCPRIRFPELIEKIE

Sequences:

>Translated_230_residues
MIKVVKVAHVQLCSCCGCLVSLADTYEKLLDVLNSIELVYCQTLADAREIPECDIALVEGSVCLDDHHSLEVAQEVRKKA
KIVVALGACAATGGVTRYCKGNQLSKPVHSSFSPLTEVIKVDLAIPGCPPSPEAIVGVITAALNGDMEYLQPYAELAEKG
SEACGCDVIYKVVNKSLCMGCGTCAAACPTRAIEMLDGRPNVLKELCIKCGACSVQCPRIRFPELIEKIE
>Mature_230_residues
MIKVVKVAHVQLCSCCGCLVSLADTYEKLLDVLNSIELVYCQTLADAREIPECDIALVEGSVCLDDHHSLEVAQEVRKKA
KIVVALGACAATGGVTRYCKGNQLSKPVHSSFSPLTEVIKVDLAIPGCPPSPEAIVGVITAALNGDMEYLQPYAELAEKG
SEACGCDVIYKVVNKSLCMGCGTCAAACPTRAIEMLDGRPNVLKELCIKCGACSVQCPRIRFPELIEKIE

Specific function: Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen

COG id: COG1941

COG function: function code C; Coenzyme F420-reducing hydrogenase, gamma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRHG_METJA (Q60340)

Other databases:

- EMBL:   L77117
- PIR:   G64303
- RefSeq:   NP_246994.1
- ProteinModelPortal:   Q60340
- SMR:   Q60340
- GeneID:   1450869
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0031
- NMPDR:   fig|243232.1.peg.31
- TIGR:   MJ0031
- HOGENOM:   HBG538706
- OMA:   MYDVINQ
- ProtClustDB:   CLSK876042
- BioCyc:   MJAN243232:MJ_0031-MONOMER
- BRENDA:   1.12.98.1
- GO:   GO:0006810
- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017681
- InterPro:   IPR006137
- InterPro:   IPR014406
- InterPro:   IPR001821
- PANTHER:   PTHR11995
- PRINTS:   PR00614
- TIGRFAMs:   TIGR03294

Pfam domain/function: PF00037 Fer4; PF01058 Oxidored_q6

EC number: =1.12.98.1

Molecular weight: Translated: 24534; Mature: 24534

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
10.4 %Cys+Met (Translated Protein)
8.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
10.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVVKVAHVQLCSCCGCLVSLADTYEKLLDVLNSIELVYCQTLADAREIPECDIALVEG
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
SVCLDDHHSLEVAQEVRKKAKIVVALGACAATGGVTRYCKGNQLSKPVHSSFSPLTEVIK
CEEECCCHHHHHHHHHHHHHHEEEEECHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHH
VDLAIPGCPPSPEAIVGVITAALNGDMEYLQPYAELAEKGSEACGCDVIYKVVNKSLCMG
HHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
CGTCAAACPTRAIEMLDGRPNVLKELCIKCGACSVQCPRIRFPELIEKIE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MIKVVKVAHVQLCSCCGCLVSLADTYEKLLDVLNSIELVYCQTLADAREIPECDIALVEG
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
SVCLDDHHSLEVAQEVRKKAKIVVALGACAATGGVTRYCKGNQLSKPVHSSFSPLTEVIK
CEEECCCHHHHHHHHHHHHHHEEEEECHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHH
VDLAIPGCPPSPEAIVGVITAALNGDMEYLQPYAELAEKGSEACGCDVIYKVVNKSLCMG
HHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
CGTCAAACPTRAIEMLDGRPNVLKELCIKCGACSVQCPRIRFPELIEKIE
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087