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The map label for this gene is yfdZ [C]

Identifier: 15668173

GI number: 15668173

Start: 2216

End: 3343

Strand: Reverse

Name: yfdZ [C]

Synonym: MJ0001

Alternate gene names: 15668173

Gene position: 3343-2216 (Counterclockwise)

Preceding gene: 15668174

Following gene: NA

Centisome position: 0.2

GC content: 33.69

Gene sequence:

>1128_bases
ATGATAAGCAGTAGATGCAAAAATATAAAACCATCAGCAATTAGGGAGATATTTAACTTAGCTACATCTGATTGCATAAA
TTTAGGAATAGGAGAGCCAGATTTTGACACTCCAAAGCATATCATTGAGGCTGCAAAAAGGGCTTTAGATGAGGGGAAAA
CTCACTACTCTCCAAACAATGGAATTCCAGAGCTTAGAGAGGAGATAAGCAATAAGTTAAAGGATGATTACAACTTAGAC
GTTGATAAGGACAATATTATTGTTACCTGTGGAGCTTCAGAGGCGTTAATGTTATCTATTATGACTTTGATTGACAGAGG
GGATGAGGTTTTAATTCCAAATCCATCTTTTGTGTCTTATTTTTCACTAACAGAGTTTGCTGAGGGTAAGATTAAGAATA
TAGATTTAGATGAAAACTTTAATATTGATTTAGAGAAAGTTAAAGAATCAATAACTAAAAAAACAAAGCTAATAATATTT
AACTCTCCATCAAATCCTACTGGAAAAGTCTATGATAAGGAGACCATAAAAGGCTTGGCAGAGATTGCTGAGGATTATAA
TCTAATTATTGTTTCAGATGAAGTCTATGATAAGATTATCTACGATAAGAAGCATTACTCTCCAATGCAATTTACTGATA
GATGCATATTAATTAACGGTTTCTCTAAAACCTATGCCATGACTGGATGGAGGATTGGATATTTGGCTGTTTCTGATGAA
CTAAATAAGGAGTTAGATTTAATCAACAATATGATTAAGATTCATCAGTATAGCTTTGCATGTGCTACAACCTTTGCTCA
ATATGGGGCATTAGCAGCTTTAAGAGGTAGTCAAAAGTGTGTTGAGGATATGGTTAGAGAGTTTAAAATGAGGAGAGATT
TAATCTATAATGGATTGAAGGATATCTTTAAAGTCAATAAGCCAGATGGGGCATTCTATATATTCCCAGATGTTTCTGAG
TATGGAGATGGGGTAGAGGTAGCTAAGAAATTGATTGAGAATAAGGTTTTATGTGTTCCTGGAGTTGCATTTGGTGAGAA
TGGAGCTAACTATATTAGGTTCAGCTATGCTACAAAATATGAAGATATAGAGAAAGCTTTAGGGATTATAAAAGAGATTT
TTGAGTGA

Upstream 100 bases:

>100_bases
AGAGCTATAAAAACTCTAACCTAATTGATGAGCCATCAGAAACTGCAAAGATTAAGGCTATAGAGCTTTATAAAAAGCTA
TACTTTGAGGATGTGAGAGA

Downstream 100 bases:

>100_bases
ATTTTTAGTATTTTATTTTAATGCTCATTTCTCTTCTGATTTTAATAAAAGAGTGTAGAAAAGAGTAATTGAGTTTAATA
AAGAAAAACGTTTTATCCCG

Product: aspartate aminotransferase AspB

Products: NA

Alternate protein names: AspAT; Transaminase A

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MISSRCKNIKPSAIREIFNLATSDCINLGIGEPDFDTPKHIIEAAKRALDEGKTHYSPNNGIPELREEISNKLKDDYNLD
VDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNPSFVSYFSLTEFAEGKIKNIDLDENFNIDLEKVKESITKKTKLIIF
NSPSNPTGKVYDKETIKGLAEIAEDYNLIIVSDEVYDKIIYDKKHYSPMQFTDRCILINGFSKTYAMTGWRIGYLAVSDE
LNKELDLINNMIKIHQYSFACATTFAQYGALAALRGSQKCVEDMVREFKMRRDLIYNGLKDIFKVNKPDGAFYIFPDVSE
YGDGVEVAKKLIENKVLCVPGVAFGENGANYIRFSYATKYEDIEKALGIIKEIFE

Sequences:

>Translated_375_residues
MISSRCKNIKPSAIREIFNLATSDCINLGIGEPDFDTPKHIIEAAKRALDEGKTHYSPNNGIPELREEISNKLKDDYNLD
VDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNPSFVSYFSLTEFAEGKIKNIDLDENFNIDLEKVKESITKKTKLIIF
NSPSNPTGKVYDKETIKGLAEIAEDYNLIIVSDEVYDKIIYDKKHYSPMQFTDRCILINGFSKTYAMTGWRIGYLAVSDE
LNKELDLINNMIKIHQYSFACATTFAQYGALAALRGSQKCVEDMVREFKMRRDLIYNGLKDIFKVNKPDGAFYIFPDVSE
YGDGVEVAKKLIENKVLCVPGVAFGENGANYIRFSYATKYEDIEKALGIIKEIFE
>Mature_375_residues
MISSRCKNIKPSAIREIFNLATSDCINLGIGEPDFDTPKHIIEAAKRALDEGKTHYSPNNGIPELREEISNKLKDDYNLD
VDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNPSFVSYFSLTEFAEGKIKNIDLDENFNIDLEKVKESITKKTKLIIF
NSPSNPTGKVYDKETIKGLAEIAEDYNLIIVSDEVYDKIIYDKKHYSPMQFTDRCILINGFSKTYAMTGWRIGYLAVSDE
LNKELDLINNMIKIHQYSFACATTFAQYGALAALRGSQKCVEDMVREFKMRRDLIYNGLKDIFKVNKPDGAFYIFPDVSE
YGDGVEVAKKLIENKVLCVPGVAFGENGANYIRFSYATKYEDIEKALGIIKEIFE

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI95147551, Length=405, Percent_Identity=26.1728395061728, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI169881279, Length=405, Percent_Identity=26.1728395061728, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4507369, Length=375, Percent_Identity=28.2666666666667, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI56713254, Length=324, Percent_Identity=29.0123456790123, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI56713256, Length=324, Percent_Identity=29.0123456790123, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI169881281, Length=381, Percent_Identity=23.6220472440945, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI215599424, Length=415, Percent_Identity=23.1325301204819, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI19263340, Length=420, Percent_Identity=23.0952380952381, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI149944424, Length=238, Percent_Identity=24.7899159663866, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI7705897, Length=371, Percent_Identity=23.4501347708895, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI33469970, Length=371, Percent_Identity=23.4501347708895, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1788722, Length=365, Percent_Identity=33.4246575342466, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1786816, Length=362, Percent_Identity=28.1767955801105, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1788627, Length=381, Percent_Identity=29.9212598425197, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787710, Length=334, Percent_Identity=24.251497005988, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787909, Length=371, Percent_Identity=22.1024258760108, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790797, Length=343, Percent_Identity=22.4489795918367, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=399, Percent_Identity=26.8170426065163, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=399, Percent_Identity=26.8170426065163, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=29.7297297297297, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=320, Percent_Identity=28.75, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71981209, Length=384, Percent_Identity=23.1770833333333, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=321, Percent_Identity=28.6604361370716, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6320317, Length=367, Percent_Identity=25.6130790190736, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323118, Length=373, Percent_Identity=26.2734584450402, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28573069, Length=416, Percent_Identity=26.6826923076923, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24646114, Length=416, Percent_Identity=26.6826923076923, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28573067, Length=416, Percent_Identity=26.6826923076923, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28573065, Length=416, Percent_Identity=26.6826923076923, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859735, Length=386, Percent_Identity=26.1658031088083, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21356535, Length=382, Percent_Identity=25.130890052356, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24641770, Length=375, Percent_Identity=23.4666666666667, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641760, Length=375, Percent_Identity=23.4666666666667, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641768, Length=375, Percent_Identity=23.4666666666667, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641766, Length=375, Percent_Identity=23.4666666666667, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641764, Length=375, Percent_Identity=23.4666666666667, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45551451, Length=375, Percent_Identity=23.4666666666667, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AAT1_METJA (Q60317)

Other databases:

- EMBL:   L77117
- PIR:   A64300
- RefSeq:   NP_246964.1
- ProteinModelPortal:   Q60317
- SMR:   Q60317
- GeneID:   1450840
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0001
- NMPDR:   fig|243232.1.peg.1
- TIGR:   MJ0001
- HOGENOM:   HBG645860
- OMA:   CILINGF
- ProtClustDB:   CLSK876028
- BioCyc:   MJAN243232:MJ_0001-MONOMER
- BRENDA:   2.6.1.1
- GO:   GO:0005737
- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PRINTS:   PR00753

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.1

Molecular weight: Translated: 42396; Mature: 42396

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: BINDING 31-31 BINDING 165-165 BINDING 353-353

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSRCKNIKPSAIREIFNLATSDCINLGIGEPDFDTPKHIIEAAKRALDEGKTHYSPNN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GIPELREEISNKLKDDYNLDVDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNPSFVSY
CCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCHHHH
FSLTEFAEGKIKNIDLDENFNIDLEKVKESITKKTKLIIFNSPSNPTGKVYDKETIKGLA
HHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHH
EIAEDYNLIIVSDEVYDKIIYDKKHYSPMQFTDRCILINGFSKTYAMTGWRIGYLAVSDE
HHHCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHEECCEEEEEEEECHH
LNKELDLINNMIKIHQYSFACATTFAQYGALAALRGSQKCVEDMVREFKMRRDLIYNGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DIFKVNKPDGAFYIFPDVSEYGDGVEVAKKLIENKVLCVPGVAFGENGANYIRFSYATKY
HHHCCCCCCCCEEECCCHHHHCCHHHHHHHHHCCCEEEECCCEECCCCCCEEEEEEHHHH
EDIEKALGIIKEIFE
HHHHHHHHHHHHHHC
>Mature Secondary Structure
MISSRCKNIKPSAIREIFNLATSDCINLGIGEPDFDTPKHIIEAAKRALDEGKTHYSPNN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GIPELREEISNKLKDDYNLDVDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNPSFVSY
CCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCHHHH
FSLTEFAEGKIKNIDLDENFNIDLEKVKESITKKTKLIIFNSPSNPTGKVYDKETIKGLA
HHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHH
EIAEDYNLIIVSDEVYDKIIYDKKHYSPMQFTDRCILINGFSKTYAMTGWRIGYLAVSDE
HHHCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHEECCEEEEEEEECHH
LNKELDLINNMIKIHQYSFACATTFAQYGALAALRGSQKCVEDMVREFKMRRDLIYNGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DIFKVNKPDGAFYIFPDVSEYGDGVEVAKKLIENKVLCVPGVAFGENGANYIRFSYATKY
HHHCCCCCCCCEEECCCHHHHCCHHHHHHHHHCCCEEEECCCEECCCCCCEEEEEEHHHH
EDIEKALGIIKEIFE
HHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087