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Identifier: 15646179

GI number: 15646179

Start: 1652651

End: 1653769

Strand: Reverse

Name: Not Available

Synonym: HP1572

Alternate gene names: 15646179

Gene position: 1653769-1652651 (Counterclockwise)

Preceding gene: 15646180

Following gene: 15646178

Centisome position: 99.15

GC content: 38.78

Gene sequence:

>1119_bases
ATGTCAAAAAGAATGAAGTGTTTTAGTCAAAAATGGTTGGTTTTTTTTGTTACCCTTTTATTGGCTTCTTTAGGCCATGC
GAAAATGGCTTTTGAATCCGATATTGACACCAAAGCGCTAGAGGCTTTTGGGGTTAATGCGGGCTTTTTATCCCAAATGC
CCAACGCTTTAAAAAAAATGAATAAAGAAGAAGAATGGAAGAGACTTGTCAAAAGATTTGATGTGAATTACCAGTTCATC
CCCATCATTAAAAACATGCTCATAGAAGCGAGCGTGCCGCAAGAATTTTTATTTTTAGCCATGGCCGAGTCTAAATTTTC
ATCAAGGGCTTATAGCAGGAAAAAAGCGGTAGGGATTTGGCAATTCATGCCAAGCACGGCTAAAGAATTAGGGCTTAAGG
TCAATCATTACATTGATGAAAGAAGAGATCCCATTAAAAGCACTCAAGCGGCGATCACTTATTTGAAACGGCTCTACAAG
CAAACCGGAGAGTGGTATTTGGTCGCTATGGCGTATAATTACGGCTTACGCAAGGTTCAAAACGCTATTAAAGCCGCCGG
CACTTCGGACATTAAAATTTTGTTGGATGAAGATAAGAAATACCTCCCTAAAGAAACACGAGAGTATATCCGCTCCATTC
TAAGCCTAGCGTTAAAATTCAACAGCCTAGACAACCTCAAAGATAAAGAATATCTGCTCAATCGTGGGGCGAGGGTGAGT
TTAGTGGGCGTCCCGTTTAAAAGGCGTGCTTCTTTAGTCCAAGTAGCCAAAAATTTGAATTTGAGTTTGGAAACCTTAAA
ATCCTACAACCACCAATTCCGTTATAACATTCTGCCTTCTAAAGACCCCACTTATACCATTTATATCCCTTATGAAAAAC
TCGCTCTTTTCAAACAACGCCAGATCAAACAAAATAAAAACATTCAAGCCAGTTCAAAAAGCCCTTTTATCACCCATGTG
GTCTTACCTAAAGAAACCCTATCTTCTATCGCTAAACGCTATCAAGTCAGTATTTCCAATATCCAATTAGCCAATGATCT
CAAAGATTCTAATATTTTTATCCACCAGCGTTTAATCATCCCCACCAACAAAAAATTACTCGCTACAAGGGAATTTTAA

Upstream 100 bases:

>100_bases
TAGTTTCCCCTAAAATAAGGCTGTGTTAGAAAGCGTTATTCAAGTTTAGTTATAATCAAAGCTATTTTAAAAGCTGAATA
GCTATAGTTATTAGGATGCG

Downstream 100 bases:

>100_bases
TGGGTTTGGCGTTGGAAAAAGTTTGTTTTTTAGGCGTTATTTTTTTGATTAGCGCTTGCACGGTTAAAAAAGAGGGGGTA
AAGAATTTGTCTTACAAGCA

Product: regulatory protein DniR

Products: 1,6-Anhydrobond In The Muramic Acid Residue [C]

Alternate protein names: Murein hydrolase D; Regulatory protein dniR [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSKRMKCFSQKWLVFFVTLLLASLGHAKMAFESDIDTKALEAFGVNAGFLSQMPNALKKMNKEEEWKRLVKRFDVNYQFI
PIIKNMLIEASVPQEFLFLAMAESKFSSRAYSRKKAVGIWQFMPSTAKELGLKVNHYIDERRDPIKSTQAAITYLKRLYK
QTGEWYLVAMAYNYGLRKVQNAIKAAGTSDIKILLDEDKKYLPKETREYIRSILSLALKFNSLDNLKDKEYLLNRGARVS
LVGVPFKRRASLVQVAKNLNLSLETLKSYNHQFRYNILPSKDPTYTIYIPYEKLALFKQRQIKQNKNIQASSKSPFITHV
VLPKETLSSIAKRYQVSISNIQLANDLKDSNIFIHQRLIIPTNKKLLATREF

Sequences:

>Translated_372_residues
MSKRMKCFSQKWLVFFVTLLLASLGHAKMAFESDIDTKALEAFGVNAGFLSQMPNALKKMNKEEEWKRLVKRFDVNYQFI
PIIKNMLIEASVPQEFLFLAMAESKFSSRAYSRKKAVGIWQFMPSTAKELGLKVNHYIDERRDPIKSTQAAITYLKRLYK
QTGEWYLVAMAYNYGLRKVQNAIKAAGTSDIKILLDEDKKYLPKETREYIRSILSLALKFNSLDNLKDKEYLLNRGARVS
LVGVPFKRRASLVQVAKNLNLSLETLKSYNHQFRYNILPSKDPTYTIYIPYEKLALFKQRQIKQNKNIQASSKSPFITHV
VLPKETLSSIAKRYQVSISNIQLANDLKDSNIFIHQRLIIPTNKKLLATREF
>Mature_371_residues
SKRMKCFSQKWLVFFVTLLLASLGHAKMAFESDIDTKALEAFGVNAGFLSQMPNALKKMNKEEEWKRLVKRFDVNYQFIP
IIKNMLIEASVPQEFLFLAMAESKFSSRAYSRKKAVGIWQFMPSTAKELGLKVNHYIDERRDPIKSTQAAITYLKRLYKQ
TGEWYLVAMAYNYGLRKVQNAIKAAGTSDIKILLDEDKKYLPKETREYIRSILSLALKFNSLDNLKDKEYLLNRGARVSL
VGVPFKRRASLVQVAKNLNLSLETLKSYNHQFRYNILPSKDPTYTIYIPYEKLALFKQRQIKQNKNIQASSKSPFITHVV
LPKETLSSIAKRYQVSISNIQLANDLKDSNIFIHQRLIIPTNKKLLATREF

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786405, Length=288, Percent_Identity=31.5972222222222, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR010511
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01476 LysM; PF06474 MLTD_N; PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 43089; Mature: 42958

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRMKCFSQKWLVFFVTLLLASLGHAKMAFESDIDTKALEAFGVNAGFLSQMPNALKKM
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHC
NKEEEWKRLVKRFDVNYQFIPIIKNMLIEASVPQEFLFLAMAESKFSSRAYSRKKAVGIW
CCHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFMPSTAKELGLKVNHYIDERRDPIKSTQAAITYLKRLYKQTGEWYLVAMAYNYGLRKVQ
HHCCHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHH
NAIKAAGTSDIKILLDEDKKYLPKETREYIRSILSLALKFNSLDNLKDKEYLLNRGARVS
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEE
LVGVPFKRRASLVQVAKNLNLSLETLKSYNHQFRYNILPSKDPTYTIYIPYEKLALFKQR
EEECCHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCEEEEECHHHHHHHHHH
QIKQNKNIQASSKSPFITHVVLPKETLSSIAKRYQVSISNIQLANDLKDSNIFIHQRLII
HHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEEEE
PTNKKLLATREF
CCCCCEEEECCC
>Mature Secondary Structure 
SKRMKCFSQKWLVFFVTLLLASLGHAKMAFESDIDTKALEAFGVNAGFLSQMPNALKKM
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHC
NKEEEWKRLVKRFDVNYQFIPIIKNMLIEASVPQEFLFLAMAESKFSSRAYSRKKAVGIW
CCHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFMPSTAKELGLKVNHYIDERRDPIKSTQAAITYLKRLYKQTGEWYLVAMAYNYGLRKVQ
HHCCHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHH
NAIKAAGTSDIKILLDEDKKYLPKETREYIRSILSLALKFNSLDNLKDKEYLLNRGARVS
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEE
LVGVPFKRRASLVQVAKNLNLSLETLKSYNHQFRYNILPSKDPTYTIYIPYEKLALFKQR
EEECCHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCEEEEECHHHHHHHHHH
QIKQNKNIQASSKSPFITHVVLPKETLSSIAKRYQVSISNIQLANDLKDSNIFIHQRLII
HHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEEEE
PTNKKLLATREF
CCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]