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The map label for this gene is murB

Identifier: 15646027

GI number: 15646027

Start: 1488625

End: 1489404

Strand: Reverse

Name: murB

Synonym: HP1418

Alternate gene names: 15646027

Gene position: 1489404-1488625 (Counterclockwise)

Preceding gene: 15646028

Following gene: 15646023

Centisome position: 89.3

GC content: 41.67

Gene sequence:

>780_bases
ATGCTAGAAACCACCATTGATTTTTCTCGTTACAGCAGCGTGAAAATCGGCACGCCTTTAAAAGTGAGCGTTTTAGAAAA
CGATGATGAAATCTCTCAAGAACACCAGATCATAGGCTTAGCGAACAACCTTTTAATCGCTCCTAGCGCGAAAAATCTCG
CTTTATTAGGAAAAAACTACGATTATATTTGCGATAAGGGCGAATGCGTTGAAATAGGGGGAGCGGCCAATGCGTCTAAA
ATTTTTAATTATTTTAGGGCGAATGATTTAGAGGGTTTGGAATTTTTAGGGCAATTGCCTGGCACTTTAGGAGCGTTAGT
TAAAATGAATGCCGGCATGAAAGAATTTGAAATCAAAAATGTTTTAGAAAGCGCTTGCATTAATAATCAATGGCTAGAAA
AAGAAGCTTTGGGGCTGGGCTATCGCAGCAGCGGGTTTAGTGGCGTTGTCTTAAGAGCGAGATTTAAAAAAACGCATGGC
TTTAGAGAAGGGGTTTTAAAAGCGTGTCAAAGCATGCGCAAAAGCCACCCCAAATTGCCTAATTTTGGGAGTTGTTTCAA
AAACCCGCCTAACGATCATGCGGGCAGGCTTTTAGAGGGCGTGGGCTTAAGGGGTTATTGTCTAAAAAGAGTGGGCTTTG
CCAAAGAGCATGCGAATTTTTTGGTGAATTTGGGGGGCGCAGAATTTGAAGAAGCCCTAGATCTGATAGAGCTCGCTAAA
GCTAGAGTGTTACAAGAATACGGCATTCATTTGGAAGAAGAAGTGAAGATTTTGAGATAG

Upstream 100 bases:

>100_bases
GATTGGGGTGCTGATTTTAACCATGCCGTGGATGACGAACATGCTTTTAGATTACACCAAAACCTTAATCAAGCTCATTC
CCAAAATCATCGGCTAGAAA

Downstream 100 bases:

>100_bases
GGTTGAAAAGCTTTATTTGGAATCAAGCTTATCCCTATTAATGAGAACAGAGCCTTATTATTATTTAGTCCTATCATAAT
TCATGCTGCCATAACAAACA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLETTIDFSRYSSVKIGTPLKVSVLENDDEISQEHQIIGLANNLLIAPSAKNLALLGKNYDYICDKGECVEIGGAANASK
IFNYFRANDLEGLEFLGQLPGTLGALVKMNAGMKEFEIKNVLESACINNQWLEKEALGLGYRSSGFSGVVLRARFKKTHG
FREGVLKACQSMRKSHPKLPNFGSCFKNPPNDHAGRLLEGVGLRGYCLKRVGFAKEHANFLVNLGGAEFEEALDLIELAK
ARVLQEYGIHLEEEVKILR

Sequences:

>Translated_259_residues
MLETTIDFSRYSSVKIGTPLKVSVLENDDEISQEHQIIGLANNLLIAPSAKNLALLGKNYDYICDKGECVEIGGAANASK
IFNYFRANDLEGLEFLGQLPGTLGALVKMNAGMKEFEIKNVLESACINNQWLEKEALGLGYRSSGFSGVVLRARFKKTHG
FREGVLKACQSMRKSHPKLPNFGSCFKNPPNDHAGRLLEGVGLRGYCLKRVGFAKEHANFLVNLGGAEFEEALDLIELAK
ARVLQEYGIHLEEEVKILR
>Mature_259_residues
MLETTIDFSRYSSVKIGTPLKVSVLENDDEISQEHQIIGLANNLLIAPSAKNLALLGKNYDYICDKGECVEIGGAANASK
IFNYFRANDLEGLEFLGQLPGTLGALVKMNAGMKEFEIKNVLESACINNQWLEKEALGLGYRSSGFSGVVLRARFKKTHG
FREGVLKACQSMRKSHPKLPNFGSCFKNPPNDHAGRLLEGVGLRGYCLKRVGFAKEHANFLVNLGGAEFEEALDLIELAK
ARVLQEYGIHLEEEVKILR

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the murB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR003170
- InterPro:   IPR011601 [H]

Pfam domain/function: PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 28592; Mature: 28592

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETTIDFSRYSSVKIGTPLKVSVLENDDEISQEHQIIGLANNLLIAPSAKNLALLGKNY
CCCCCCCHHHCCCEECCCCEEEEEECCCHHHHHHHHEEEEECCEEEECCCCCEEEECCCC
DYICDKGECVEIGGAANASKIFNYFRANDLEGLEFLGQLPGTLGALVKMNAGMKEFEIKN
CEEECCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
VLESACINNQWLEKEALGLGYRSSGFSGVVLRARFKKTHGFREGVLKACQSMRKSHPKLP
HHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
NFGSCFKNPPNDHAGRLLEGVGLRGYCLKRVGFAKEHANFLVNLGGAEFEEALDLIELAK
CCCHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHCCEEEECCCCCHHHHHHHHHHHH
ARVLQEYGIHLEEEVKILR
HHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MLETTIDFSRYSSVKIGTPLKVSVLENDDEISQEHQIIGLANNLLIAPSAKNLALLGKNY
CCCCCCCHHHCCCEECCCCEEEEEECCCHHHHHHHHEEEEECCEEEECCCCCEEEECCCC
DYICDKGECVEIGGAANASKIFNYFRANDLEGLEFLGQLPGTLGALVKMNAGMKEFEIKN
CEEECCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
VLESACINNQWLEKEALGLGYRSSGFSGVVLRARFKKTHGFREGVLKACQSMRKSHPKLP
HHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
NFGSCFKNPPNDHAGRLLEGVGLRGYCLKRVGFAKEHANFLVNLGGAEFEEALDLIELAK
CCCHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHCCEEEECCCCCHHHHHHHHHHHH
ARVLQEYGIHLEEEVKILR
HHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]