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Identifier: 15645976

GI number: 15645976

Start: 1425795

End: 1426988

Strand: Reverse

Name: Not Available

Synonym: HP1364

Alternate gene names: 15645976

Gene position: 1426988-1425795 (Counterclockwise)

Preceding gene: 15645977

Following gene: 15645975

Centisome position: 85.56

GC content: 37.1

Gene sequence:

>1194_bases
TTGGCTATCGCTTTAACCCACTATGAAAAAAAATCCCTTAAACTCTTTTTAGGGATTTATTTAGGCTCTTCGTTTGTGTT
GATGCTAGTGATTAGCGTTTTAGCGTTTAACTATGAAAAAAACGAAAAAATCAAAATGATACGCATGGACATGGACAAAA
TGGCTTCTAAGATCGCTAGCGAAGTGATTGCCTTGCACATGCAAACGCATGGGGATTATCAAAACGCTTTAAACGCTCTC
ATTTCACGCTATAAAGACGCTTCCATAGCCCTTTTTGATAGTAAAAAGCGTGTTTTGTATTCTAATATCCCTGAAAGCGC
CAATTTGATTAAAAACCATAAAGAAGCGGGCTTTTTTAGTTTTAGGGGAGAGTATTACCTATTGAGCGATGAAACTTTCG
CTCACTTAGGCGTGGCTAAAATGCTTTTTAAAAATTCTAAACCCCTTCATTTTTCTTCTTTGTATCGTAACATTGTTTTA
GTGTTTGTTGTAGCGTTTTTATGCGTGATAGGGGTTTCTGTGTTTTTGGGGCGTTTGTTTTTAAAGCCCATTAGGAATGA
AATCACCCGCATTGATCATTTTTTAAAAAACACCACGCATGAATTAAACACCCCCATGAGCGCTTTAGTCTTGTCTTTAA
AAACCTTAGAAGACAACCAACAACACCGCCGCATTAAAATCGCTATCCAGCGCATGAGTTTTTTATACCGCTCGCTCTCG
TATTTAGTGATGCAAGATATTGAGCGCGAATCTTTTGTGCTTTTAGATTTAAAAGCCCTGATTATTAAAGAAAACACGCT
TTTTAGCGAGATGATAGACTACCACAAGCTGGAATTTAAAAGCGATTTAGTGGAAGTGGAACTTAAAGCTAAAGAGCAGG
ATTTCATTTCGCTTTATAGCAATTTGCTCATGAACGCGATCAAATACAGCGTCATGAATGGGTATATCCACATAGAGCTA
ACGCATGCGTTTTTGAAAGTGAAAAATTTAGGGTATGAAATCCCTAAAGACAAGATCACAGAATTAAGCGTTCGTTATGT
GCGTTTCAATTCTGGCGTGTTGGGTTATGGTATAGGGTTAGGTTTGGTGAAAAAAGTGTGCGAAAAGTATAAAATGCGTT
TAGAAATTCATAGCGAACCCTCTTTAAAGGGATCGTTTTATGAAAATTCGTTTTGCGTTCAATTTCAAGGATAA

Upstream 100 bases:

>100_bases
AACCTATGGGAGCAAGCGATTGATGATTCCACCTTGCGCACTTATATTAAAGTGTTGCGCAAGCTTTTGGGTAAAAATTG
CATAGAAACGCATAAGGGGG

Downstream 100 bases:

>100_bases
AGATGCTTTCAGTGTATGAAAAAGTGAATGCTCTAGACAAAAGGGCGATTGAAGAATTGTTTTTAAGCGAAGACATTTTA
ATGGAAAACGCCGCTATGGC

Product: histidine kinase sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MAIALTHYEKKSLKLFLGIYLGSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIASEVIALHMQTHGDYQNALNAL
ISRYKDASIALFDSKKRVLYSNIPESANLIKNHKEAGFFSFRGEYYLLSDETFAHLGVAKMLFKNSKPLHFSSLYRNIVL
VFVVAFLCVIGVSVFLGRLFLKPIRNEITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLS
YLVMQDIERESFVLLDLKALIIKENTLFSEMIDYHKLEFKSDLVEVELKAKEQDFISLYSNLLMNAIKYSVMNGYIHIEL
THAFLKVKNLGYEIPKDKITELSVRYVRFNSGVLGYGIGLGLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCVQFQG

Sequences:

>Translated_397_residues
MAIALTHYEKKSLKLFLGIYLGSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIASEVIALHMQTHGDYQNALNAL
ISRYKDASIALFDSKKRVLYSNIPESANLIKNHKEAGFFSFRGEYYLLSDETFAHLGVAKMLFKNSKPLHFSSLYRNIVL
VFVVAFLCVIGVSVFLGRLFLKPIRNEITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLS
YLVMQDIERESFVLLDLKALIIKENTLFSEMIDYHKLEFKSDLVEVELKAKEQDFISLYSNLLMNAIKYSVMNGYIHIEL
THAFLKVKNLGYEIPKDKITELSVRYVRFNSGVLGYGIGLGLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCVQFQG
>Mature_396_residues
AIALTHYEKKSLKLFLGIYLGSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIASEVIALHMQTHGDYQNALNALI
SRYKDASIALFDSKKRVLYSNIPESANLIKNHKEAGFFSFRGEYYLLSDETFAHLGVAKMLFKNSKPLHFSSLYRNIVLV
FVVAFLCVIGVSVFLGRLFLKPIRNEITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLSY
LVMQDIERESFVLLDLKALIIKENTLFSEMIDYHKLEFKSDLVEVELKAKEQDFISLYSNLLMNAIKYSVMNGYIHIELT
HAFLKVKNLGYEIPKDKITELSVRYVRFNSGVLGYGIGLGLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCVQFQG

Specific function: Member of the two-component regulatory system dltS/dltR. Regulates the expression of the dlt operon. Probably phosphorylates dltR [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45853; Mature: 45721

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIALTHYEKKSLKLFLGIYLGSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIAS
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHH
EVIALHMQTHGDYQNALNALISRYKDASIALFDSKKRVLYSNIPESANLIKNHKEAGFFS
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCCHHHHHHCCCCCCEEE
FRGEYYLLSDETFAHLGVAKMLFKNSKPLHFSSLYRNIVLVFVVAFLCVIGVSVFLGRLF
ECCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKPIRNEITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLS
HHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YLVMQDIERESFVLLDLKALIIKENTLFSEMIDYHKLEFKSDLVEVELKAKEQDFISLYS
HHHHHHCCCCCEEEEEHHHHHEECCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHH
NLLMNAIKYSVMNGYIHIELTHAFLKVKNLGYEIPKDKITELSVRYVRFNSGVLGYGIGL
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCCCHHHHHHEEEEEEECCCCHHHHHHH
GLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCVQFQG
HHHHHHHHHHHEEEEECCCCCCCCCEECCCEEEEECC
>Mature Secondary Structure 
AIALTHYEKKSLKLFLGIYLGSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIAS
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHH
EVIALHMQTHGDYQNALNALISRYKDASIALFDSKKRVLYSNIPESANLIKNHKEAGFFS
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCCHHHHHHCCCCCCEEE
FRGEYYLLSDETFAHLGVAKMLFKNSKPLHFSSLYRNIVLVFVVAFLCVIGVSVFLGRLF
ECCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKPIRNEITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLS
HHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YLVMQDIERESFVLLDLKALIIKENTLFSEMIDYHKLEFKSDLVEVELKAKEQDFISLYS
HHHHHHCCCCCEEEEEHHHHHEECCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHH
NLLMNAIKYSVMNGYIHIELTHAFLKVKNLGYEIPKDKITELSVRYVRFNSGVLGYGIGL
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCCCHHHHHHEEEEEEECCCCHHHHHHH
GLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCVQFQG
HHHHHHHHHHHEEEEECCCCCCCCCEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11591677; 12354221 [H]