Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15645862

GI number: 15645862

Start: 1322761

End: 1324695

Strand: Reverse

Name: Not Available

Synonym: HP1248

Alternate gene names: 15645862

Gene position: 1324695-1322761 (Counterclockwise)

Preceding gene: 15645863

Following gene: 15645861

Centisome position: 79.42

GC content: 37.67

Gene sequence:

>1935_bases
ATGCAAGGGTTTTTAAGAAGCCTGTTTTTTGGGGTTAAAAAGATCCCTAAACCATTCGCTCCTCTAGTAGAAAAGGGCGT
TTTAAAAGAAGCGCTTGAATTGAAAAAGGATCGCTATTTTTTAAAAGAAGGCTTTGATATAGGCAAAGTTGAAAAAGTAA
AAGATAAGGCGTTTTTCATTTCTTTAGCGAAAAATTACCCTAAAGACCCTTTAATCAAAAACTTACCCCCATCTTTTAAA
ACAGACGCTTTGATTTTATGCCAAATAGAATGTTCTAAAAAACGCCCCATAGCCTTTTTTAAAGCCGCTCTTTTAAATGC
AGATCACACGATGATAGCTTACTTGGCTAAAAAAAATAACCAGATTGTGGCTATCCCTTTTAAAGAGCCTTTTAAAAAAC
CTGTTTCTTTAAAGCACAGCCAAAAATCCTTACTAGAATTGCCCAGGCATTGCGTGGTAAAAATTGATACTAAAAAGCGT
GAAATCAGCGAGATTTTAGGGGCTTTAGAAGACCCTTTAATAGATGAAAACCTTTCTTTGAGCCTTTTTGACAGGGTGAA
GGATTTTTCAAAAGATTGCTTGAATTTAGCGCAACATTACGCGCAACTTAAAGCGAGCGATTTTAAAGACAGGATCAATT
ATTCTCACATCCCTTTTATCACCATTGACCCCAAAGACGCTAAAGATTTTGACGATGCGATTTTTTATGACCAAGAAAAA
AGGGTTTTGTTTGTGGCGGTTGCTGATGTGAGCGAATTTGTGCCGAAACATTCCAGTTTGGATAAAGAAGCTAGGGTTAG
GGGTTTTAGCGTGTATTTCCCTAATAGCGTCTATCCCATGCTGCCTTTGAGTTTGTCTCAAGGGGCATGCTCATTAAAAG
CGTTTGAAAAACGCCTGGCTTTAGTGTATGAAATCCCTTTAGATAATTTGAAAAACGCCCGATTATCTCAAGGCGTTATT
GAAGTTAGGGCTAATTGCACTTATGAAGAAATCAATCATTTTTTAAGCGCTAATCAAAGCTCTTTAGATAAAGATTTGCA
ACAAAGCCTTTTAGGGTTTTTAGAAATGGCTTTAAAGTTAAAAAAGGAGCGTTTAAAAAAGGGGTTTAATTTCAATTCCT
TTGAAAACAAGCTGTATTTGAATAAAGAAGGGCGTATAGAAAAAATTGAAACAGAAAAAGAAAGCGATGCGCACACCCTC
ATAGAAGAAGCCATGCTCTTAGCCAACCAATCTAGTGCGAGGTTATTGGATGAGCATTTTCACAATAAGGGGATATACCG
CACCCATAAAGAGCCCAGTTTGGAGCAGCAAAAACGCCTTTACGATAAGCTTTTTGATTATGAGATTGTGCGCCCTAAAA
ACATGGGCTTTTTTCCTTTTTTAGAGCATGCCTTAAAAATAGCCAAAGAAAAGAGTATAGAAAGAGAAGTTTCGCGCTTG
ATCATCAAGTCTCAAAATTTAGCCCTTTATAGCCCCCTGCAAGAAAGCCATTTTGGTTTGGGGTTTGCTAGCTATACGCA
TTTCACTTCGCCCATTAGACGATACAGCGATCTAGCCTTACACAGGCTTTTAAAAGAATTGTTGTTTTATCAAGCTAAAG
GCTGCTCGTATTTGTTAGAAGAAACGCCTGAATTATGCGCTGAGTTGAACGCTTTGCAAAAAAAGGCCGCTTTGATTGAA
AGGGATTTTATCAAGCGCAAATTCGCTCGCTTAGCTTTAGAACTTTTAGAAAAAGAATTTTTGGGCGTGGTTTTAGAGGT
TAAAGATTGGGTAGTGGTGGGGCTAAAAGAATTTATAGGGCTTAAAGTTTTAGTCAAAACGAACAAGGTTTTTAAGCCGT
TAGAAAAGGTGCGCGTTACAATCACGCATGCGGATTTGATTTTAGGGCAAGTTAGAGGCGAAATCACAGAAAGGATTAAA
GAGCATGTATCGTAA

Upstream 100 bases:

>100_bases
AAGACATGCTCATCTATCAAGCTGCTTTAAGTTTTGAAAAATTCAGCGCTTCTCAAATCCCTTATTCAAAAGCGTTTGAA
GTCATGCGAAGTGTTTTTTG

Downstream 100 bases:

>100_bases
AGATTTGGACCATTATTTAAAACAACGCCTCCCTAAAGCGGTGTTTTTGTATGGGGAGTTTGATTTTTTTATCCATTATT
ATATTCAAACGATTAGCGCG

Product: virulence associated protein homolog (vacB)

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MQGFLRSLFFGVKKIPKPFAPLVEKGVLKEALELKKDRYFLKEGFDIGKVEKVKDKAFFISLAKNYPKDPLIKNLPPSFK
TDALILCQIECSKKRPIAFFKAALLNADHTMIAYLAKKNNQIVAIPFKEPFKKPVSLKHSQKSLLELPRHCVVKIDTKKR
EISEILGALEDPLIDENLSLSLFDRVKDFSKDCLNLAQHYAQLKASDFKDRINYSHIPFITIDPKDAKDFDDAIFYDQEK
RVLFVAVADVSEFVPKHSSLDKEARVRGFSVYFPNSVYPMLPLSLSQGACSLKAFEKRLALVYEIPLDNLKNARLSQGVI
EVRANCTYEEINHFLSANQSSLDKDLQQSLLGFLEMALKLKKERLKKGFNFNSFENKLYLNKEGRIEKIETEKESDAHTL
IEEAMLLANQSSARLLDEHFHNKGIYRTHKEPSLEQQKRLYDKLFDYEIVRPKNMGFFPFLEHALKIAKEKSIEREVSRL
IIKSQNLALYSPLQESHFGLGFASYTHFTSPIRRYSDLALHRLLKELLFYQAKGCSYLLEETPELCAELNALQKKAALIE
RDFIKRKFARLALELLEKEFLGVVLEVKDWVVVGLKEFIGLKVLVKTNKVFKPLEKVRVTITHADLILGQVRGEITERIK
EHVS

Sequences:

>Translated_644_residues
MQGFLRSLFFGVKKIPKPFAPLVEKGVLKEALELKKDRYFLKEGFDIGKVEKVKDKAFFISLAKNYPKDPLIKNLPPSFK
TDALILCQIECSKKRPIAFFKAALLNADHTMIAYLAKKNNQIVAIPFKEPFKKPVSLKHSQKSLLELPRHCVVKIDTKKR
EISEILGALEDPLIDENLSLSLFDRVKDFSKDCLNLAQHYAQLKASDFKDRINYSHIPFITIDPKDAKDFDDAIFYDQEK
RVLFVAVADVSEFVPKHSSLDKEARVRGFSVYFPNSVYPMLPLSLSQGACSLKAFEKRLALVYEIPLDNLKNARLSQGVI
EVRANCTYEEINHFLSANQSSLDKDLQQSLLGFLEMALKLKKERLKKGFNFNSFENKLYLNKEGRIEKIETEKESDAHTL
IEEAMLLANQSSARLLDEHFHNKGIYRTHKEPSLEQQKRLYDKLFDYEIVRPKNMGFFPFLEHALKIAKEKSIEREVSRL
IIKSQNLALYSPLQESHFGLGFASYTHFTSPIRRYSDLALHRLLKELLFYQAKGCSYLLEETPELCAELNALQKKAALIE
RDFIKRKFARLALELLEKEFLGVVLEVKDWVVVGLKEFIGLKVLVKTNKVFKPLEKVRVTITHADLILGQVRGEITERIK
EHVS
>Mature_644_residues
MQGFLRSLFFGVKKIPKPFAPLVEKGVLKEALELKKDRYFLKEGFDIGKVEKVKDKAFFISLAKNYPKDPLIKNLPPSFK
TDALILCQIECSKKRPIAFFKAALLNADHTMIAYLAKKNNQIVAIPFKEPFKKPVSLKHSQKSLLELPRHCVVKIDTKKR
EISEILGALEDPLIDENLSLSLFDRVKDFSKDCLNLAQHYAQLKASDFKDRINYSHIPFITIDPKDAKDFDDAIFYDQEK
RVLFVAVADVSEFVPKHSSLDKEARVRGFSVYFPNSVYPMLPLSLSQGACSLKAFEKRLALVYEIPLDNLKNARLSQGVI
EVRANCTYEEINHFLSANQSSLDKDLQQSLLGFLEMALKLKKERLKKGFNFNSFENKLYLNKEGRIEKIETEKESDAHTL
IEEAMLLANQSSARLLDEHFHNKGIYRTHKEPSLEQQKRLYDKLFDYEIVRPKNMGFFPFLEHALKIAKEKSIEREVSRL
IIKSQNLALYSPLQESHFGLGFASYTHFTSPIRRYSDLALHRLLKELLFYQAKGCSYLLEETPELCAELNALQKKAALIE
RDFIKRKFARLALELLEKEFLGVVLEVKDWVVVGLKEFIGLKVLVKTNKVFKPLEKVRVTITHADLILGQVRGEITERIK
EHVS

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=395, Percent_Identity=29.1139240506329, Blast_Score=133, Evalue=6e-31,
Organism=Homo sapiens, GI190014625, Length=395, Percent_Identity=29.1139240506329, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI134288890, Length=385, Percent_Identity=27.012987012987, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI219521928, Length=379, Percent_Identity=27.9683377308707, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI19115966, Length=379, Percent_Identity=27.9683377308707, Blast_Score=109, Evalue=6e-24,
Organism=Escherichia coli, GI87082383, Length=400, Percent_Identity=35, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1787542, Length=375, Percent_Identity=27.4666666666667, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI212645896, Length=393, Percent_Identity=28.7531806615776, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17553506, Length=406, Percent_Identity=27.8325123152709, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324552, Length=434, Percent_Identity=27.8801843317972, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323943, Length=469, Percent_Identity=24.7334754797441, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24649634, Length=481, Percent_Identity=26.6112266112266, Blast_Score=119, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24654592, Length=425, Percent_Identity=27.5294117647059, Blast_Score=116, Evalue=6e-26,
Organism=Drosophila melanogaster, GI19922976, Length=427, Percent_Identity=27.4004683840749, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24654597, Length=427, Percent_Identity=27.4004683840749, Blast_Score=115, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR011805 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 74163; Mature: 74163

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGFLRSLFFGVKKIPKPFAPLVEKGVLKEALELKKDRYFLKEGFDIGKVEKVKDKAFFI
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SLAKNYPKDPLIKNLPPSFKTDALILCQIECSKKRPIAFFKAALLNADHTMIAYLAKKNN
HHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHEECCCC
QIVAIPFKEPFKKPVSLKHSQKSLLELPRHCVVKIDTKKREISEILGALEDPLIDENLSL
CEEEECCHHCCCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCH
SLFDRVKDFSKDCLNLAQHYAQLKASDFKDRINYSHIPFITIDPKDAKDFDDAIFYDQEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHEECCCC
RVLFVAVADVSEFVPKHSSLDKEARVRGFSVYFPNSVYPMLPLSLSQGACSLKAFEKRLA
CEEEEEEHHHHHHCCCCCCCCHHHHHCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
LVYEIPLDNLKNARLSQGVIEVRANCTYEEINHFLSANQSSLDKDLQQSLLGFLEMALKL
EEEECCCCCCCCCHHHCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KKERLKKGFNFNSFENKLYLNKEGRIEKIETEKESDAHTLIEEAMLLANQSSARLLDEHF
HHHHHHCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
HNKGIYRTHKEPSLEQQKRLYDKLFDYEIVRPKNMGFFPFLEHALKIAKEKSIEREVSRL
CCCCCEECCCCCCHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IIKSQNLALYSPLQESHFGLGFASYTHFTSPIRRYSDLALHRLLKELLFYQAKGCSYLLE
HHHCCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ETPELCAELNALQKKAALIERDFIKRKFARLALELLEKEFLGVVLEVKDWVVVGLKEFIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LKVLVKTNKVFKPLEKVRVTITHADLILGQVRGEITERIKEHVS
EEEEEECCHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQGFLRSLFFGVKKIPKPFAPLVEKGVLKEALELKKDRYFLKEGFDIGKVEKVKDKAFFI
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SLAKNYPKDPLIKNLPPSFKTDALILCQIECSKKRPIAFFKAALLNADHTMIAYLAKKNN
HHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHEECCCC
QIVAIPFKEPFKKPVSLKHSQKSLLELPRHCVVKIDTKKREISEILGALEDPLIDENLSL
CEEEECCHHCCCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCH
SLFDRVKDFSKDCLNLAQHYAQLKASDFKDRINYSHIPFITIDPKDAKDFDDAIFYDQEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHEECCCC
RVLFVAVADVSEFVPKHSSLDKEARVRGFSVYFPNSVYPMLPLSLSQGACSLKAFEKRLA
CEEEEEEHHHHHHCCCCCCCCHHHHHCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
LVYEIPLDNLKNARLSQGVIEVRANCTYEEINHFLSANQSSLDKDLQQSLLGFLEMALKL
EEEECCCCCCCCCHHHCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KKERLKKGFNFNSFENKLYLNKEGRIEKIETEKESDAHTLIEEAMLLANQSSARLLDEHF
HHHHHHCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
HNKGIYRTHKEPSLEQQKRLYDKLFDYEIVRPKNMGFFPFLEHALKIAKEKSIEREVSRL
CCCCCEECCCCCCHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IIKSQNLALYSPLQESHFGLGFASYTHFTSPIRRYSDLALHRLLKELLFYQAKGCSYLLE
HHHCCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ETPELCAELNALQKKAALIERDFIKRKFARLALELLEKEFLGVVLEVKDWVVVGLKEFIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LKVLVKTNKVFKPLEKVRVTITHADLILGQVRGEITERIKEHVS
EEEEEECCHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]