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The map label for this gene is flhF

Identifier: 15645649

GI number: 15645649

Start: 1095614

End: 1096993

Strand: Reverse

Name: flhF

Synonym: HP1035

Alternate gene names: 15645649

Gene position: 1096993-1095614 (Counterclockwise)

Preceding gene: 15645650

Following gene: 15645648

Centisome position: 65.77

GC content: 38.62

Gene sequence:

>1380_bases
GTGGTGAAATTCTATACCTATAGTGGGGAGACGGCCGCTGAAGCTTTAAAGATCGCTCAAAGCCACCATGGGGTGGATAC
GCTGGTGTTTAAAACCCAAGAAATCCGTAAAAAAACGCTCACTTCTTCTGGGCTTTATGAAATCGTTGTGGCGGTTGAAG
AAGAAAGCGAAAACAAACCCTCTAAAGCCCCCCTTATTCCTGAAAGTTTGTATGATGAAGAATTGAATGAAGAAGATGTG
GTCATGCAGCTTTCAAGCACTGTAGAAGAAATGCGCAAACTCGCCGGGGTTTCATCCAGCCAGCGCCATTATAGTTTTTC
AAAAAATAAGACTCTTTTAGAAAAAGACGCTCCATTAGAGGATGCGCCTTTAGAGGCTAATAAGCAAGACGCTTTATTGC
AAGCTTTAAAAGATGAAGCCAACCATAAAAAAGAAAGAGAAAAAAGAGAAGTTAAACAAGAAGAAGAAATTAAAGACATC
AATCTGCAATTAAGCAAAATCAGAGACAGCCTGAAACTCATTCAAAACATGTTTTGGGATGAGAAAAACCCCAATTCTAT
TAATATCCCTCAAGAATTTGCAGAAATTTACAAACTGGCCAAACAAAGTGGGATGAAACCCAGCCATTTAGATGAAATCA
TGCAATTGAGCCTGGAATTGATGCCTTTACGCATGCGCGAAAATTCCGTAACGATTAAGCGTTATTTTAGAGAAGTGTTG
CGCAAAATGATCTTGTGTTGCCCTGAAGATTTGAATTTAAGGCAAAAACGCATCTTAATGCTTGTAGGGCCAACAGGCGT
GGGGAAAACGACGACTTTAGCTAAATTAGCCGCGCGCTATTCTAGGATGTTAGCTAAAAAATACAAGGTGGGCATTATCA
CTTTAGACAATTATCGCATTGGGGCTTTGGAGCAATTAAGCTGGTATGCTAATAAAATGAAAATGAGTATAGAAGCGGTG
ATTGACGCTAAGGATTTTGCTAAAGAAATTGAAGCGTTGGAATACTGCGATTTTATTTTAGTGGATACGACAGGGCATTC
GCAATACGATAAAGAAAAAATTGCCGGTTTGAAAGAATTTATAGATGGGGGTTATAATATTGATGTGTCCTTAGTGCTTT
CAGTTACCACTAAGTATGAAGACATGAAAGATATTTATGATTCTTTTGGGGTGTTAGGGATTGACACTTTAATCTTTACG
AAATTAGATGAGAGTAGGGGGTTAGGGAATTTGTTTTCTTTAGTGCATGAAAGCCAAAAACCTATCAGCTATCTTTCTGT
TGGGCAAGAAGTGCCTATGGATTTGAAAGTGGCTACTAATGAATATTTAGTGGATTGCATGCTAGATGGCTTTAGTAATC
CTAATAAGGAACAAGCATGA

Upstream 100 bases:

>100_bases
TAAGACAGAATGATTTGGCTTTACCTCACCCTAAATGGAGTGAAAGGGATTCGGTGTTAGTGCCGTTGGCTTTGCAACAA
ATTCTTTTTAAAAAAGGGGA

Downstream 100 bases:

>100_bases
ACAATCAAGCGAGCCGCTTAGATAATTTGATGAATATTAAAAACCCTAAAAGTTTTTTTGATAATAAAGGGAATACCAAA
TTCATCGCTATCACAAGCGG

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKPSKAPLIPESLYDEELNEEDV
VMQLSSTVEEMRKLAGVSSSQRHYSFSKNKTLLEKDAPLEDAPLEANKQDALLQALKDEANHKKEREKREVKQEEEIKDI
NLQLSKIRDSLKLIQNMFWDEKNPNSINIPQEFAEIYKLAKQSGMKPSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
RKMILCCPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRIGALEQLSWYANKMKMSIEAV
IDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEFIDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFT
KLDESRGLGNLFSLVHESQKPISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA

Sequences:

>Translated_459_residues
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKPSKAPLIPESLYDEELNEEDV
VMQLSSTVEEMRKLAGVSSSQRHYSFSKNKTLLEKDAPLEDAPLEANKQDALLQALKDEANHKKEREKREVKQEEEIKDI
NLQLSKIRDSLKLIQNMFWDEKNPNSINIPQEFAEIYKLAKQSGMKPSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
RKMILCCPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRIGALEQLSWYANKMKMSIEAV
IDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEFIDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFT
KLDESRGLGNLFSLVHESQKPISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA
>Mature_459_residues
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKPSKAPLIPESLYDEELNEEDV
VMQLSSTVEEMRKLAGVSSSQRHYSFSKNKTLLEKDAPLEDAPLEANKQDALLQALKDEANHKKEREKREVKQEEEIKDI
NLQLSKIRDSLKLIQNMFWDEKNPNSINIPQEFAEIYKLAKQSGMKPSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
RKMILCCPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRIGALEQLSWYANKMKMSIEAV
IDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEFIDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFT
KLDESRGLGNLFSLVHESQKPISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family

Homologues:

Organism=Escherichia coli, GI1789874, Length=213, Percent_Identity=26.2910798122066, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6325345, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FLHF_HELPY (O25679)

Other databases:

- EMBL:   AE000511
- PIR:   C64649
- RefSeq:   NP_207825.1
- ProteinModelPortal:   O25679
- SMR:   O25679
- DIP:   DIP-3259N
- MINT:   MINT-179903
- GeneID:   899570
- GenomeReviews:   AE000511_GR
- KEGG:   hpy:HP1035
- NMPDR:   fig|85962.1.peg.1022
- TIGR:   HP_1035
- HOGENOM:   HBG752478
- OMA:   ATNEYLV
- ProtClustDB:   PRK05703
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006
- SMART:   SM00382
- SMART:   SM00962
- TIGRFAMs:   TIGR03499

Pfam domain/function: PF00448 SRP54

EC number: NA

Molecular weight: Translated: 52303; Mature: 52303

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKP
CEEEEEECCCHHHHHHHHHHHCCCCHHEEECHHHHHHHHHCCCCCEEEEEEEECCCCCCC
SKAPLIPESLYDEELNEEDVVMQLSSTVEEMRKLAGVSSSQRHYSFSKNKTLLEKDAPLE
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
DAPLEANKQDALLQALKDEANHKKEREKREVKQEEEIKDINLQLSKIRDSLKLIQNMFWD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EKNPNSINIPQEFAEIYKLAKQSGMKPSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RKMILCCPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRI
HHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCC
GALEQLSWYANKMKMSIEAVIDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEF
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
IDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFTKLDESRGLGNLFSLVHESQK
HCCCCCEEEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
PISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA
CHHHHHCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKP
CEEEEEECCCHHHHHHHHHHHCCCCHHEEECHHHHHHHHHCCCCCEEEEEEEECCCCCCC
SKAPLIPESLYDEELNEEDVVMQLSSTVEEMRKLAGVSSSQRHYSFSKNKTLLEKDAPLE
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
DAPLEANKQDALLQALKDEANHKKEREKREVKQEEEIKDINLQLSKIRDSLKLIQNMFWD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EKNPNSINIPQEFAEIYKLAKQSGMKPSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RKMILCCPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRI
HHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCC
GALEQLSWYANKMKMSIEAVIDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEF
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
IDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFTKLDESRGLGNLFSLVHESQK
HCCCCCEEEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
PISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA
CHHHHHCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185