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Identifier: 15645570

GI number: 15645570

Start: 1013553

End: 1014185

Strand: Reverse

Name: Not Available

Synonym: HP0954

Alternate gene names: 15645570

Gene position: 1014185-1013553 (Counterclockwise)

Preceding gene: 15645571

Following gene: 15645569

Centisome position: 60.81

GC content: 40.6

Gene sequence:

>633_bases
ATGAAATTTTTGGATCAAGAAAAAAGAAGACAATTATTAAACGAGCGCCATTCTTGCAAGATGTTTGATAGCCATTATGA
GTTTTCTAGCACAGAATTAGAAGAAATCGCTGAAATCGCCAGGCTATCGCCAAGCTCTTACAACACGCAGCCATGGCATT
TTGTGATGGTTACTGATAAGGATTTAAAAAAACAAATTGCAGCGCACAGCTATTTCAATGAAGAGATGATTAAAAGCGCT
TCAGCGTTAATGGTGGTATGCTCTTTAAGACCCAGCGAGTTGTTACCACACGGCCACTACATGCAAAATCTCTATCCGGA
GTCTTATAAAGTTAGAGTGATCCCCTCTTTTGCTCAAATGCTTGGCGTGAGATTCAACCACAGCATGCAAAGATTAGAAA
GCTATATTTTAGAGCAATGCTATATCGCTGTGGGGCAAATTTGCATGGGCGTGAGCTTAATGGGATTGGATAGTTGCATT
ATTGGAGGCTTTGATCCTTTAAAGGTGGGCGAAGTTTTAGAAGAGCGTATCAATAAGCCTAAAATCGCATGCTTGATCGC
TTTGGGCAAGAGGGTGGCAGAAGCGAGTCAAAAATCAAGAAAATCAAAAGTTGATGCGATTACTTGGTTGTGA

Upstream 100 bases:

>100_bases
ATTTGAGCATGGGGCAGATTTTAAGCTTATTTATGGTAATTGTTTCGTTAGGGATTTTATTGTATGCTACAAAAAATTCT
AAAAAAATAAAGGAAAATCA

Downstream 100 bases:

>100_bases
TTAAACAAAATCAAAAACTTTTTAACTATAATCAAACCTAAATTAAAGTTCAAGGAGTGGCATTTTGTTTAAAAGAATGG
TTTTAATCGCTCTTTTAGGG

Product: oxygen-insensitive NAD(P)H nitroreductase

Products: NAD(P)(+); @TETR01.txt*5,6,7,8-Tetrahydropteridine!. [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKFLDQEKRRQLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTDKDLKKQIAAHSYFNEEMIKSA
SALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQMLGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCI
IGGFDPLKVGEVLEERINKPKIACLIALGKRVAEASQKSRKSKVDAITWL

Sequences:

>Translated_210_residues
MKFLDQEKRRQLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTDKDLKKQIAAHSYFNEEMIKSA
SALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQMLGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCI
IGGFDPLKVGEVLEERINKPKIACLIALGKRVAEASQKSRKSKVDAITWL
>Mature_210_residues
MKFLDQEKRRQLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTDKDLKKQIAAHSYFNEEMIKSA
SALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQMLGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCI
IGGFDPLKVGEVLEERINKPKIACLIALGKRVAEASQKSRKSKVDAITWL

Specific function: Reduction of a variety of nitroaromatic compounds using NADPH as source of reducing equivalents; two electrons are transferred [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitroreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786792, Length=160, Percent_Identity=29.375, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24068; Mature: 24068

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDQEKRRQLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTDK
CCCCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECH
DLKKQIAAHSYFNEEMIKSASALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHCCCCCEEEEECHHHHHH
LGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCIIGGFDPLKVGEVLEERINKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
KIACLIALGKRVAEASQKSRKSKVDAITWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFLDQEKRRQLLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTDK
CCCCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECH
DLKKQIAAHSYFNEEMIKSASALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHCCCCCEEEEECHHHHHH
LGVRFNHSMQRLESYILEQCYIAVGQICMGVSLMGLDSCIIGGFDPLKVGEVLEERINKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
KIACLIALGKRVAEASQKSRKSKVDAITWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H; 6,7-Dihydropteridine [C]

Specific reaction: NAD(P)H + 6,7-Dihydropteridine = NAD(P)(+) + @TETR01.txt*5,6,7,8-Tetrahydropteridine!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA