Click here to switch to the map view.

The map label for this gene is ftsK

Identifier: 15618789

GI number: 15618789

Start: 997441

End: 999861

Strand: Reverse

Name: ftsK

Synonym: CPn0880

Alternate gene names: 15618789

Gene position: 999861-997441 (Counterclockwise)

Preceding gene: 15618792

Following gene: 15618788

Centisome position: 81.27

GC content: 39.07

Gene sequence:

>2421_bases
ATGATAAGAGAAAGAAAAAAGAGCAGGCACCCTCGTCTTCCGACTTTGCCTTTAGCAGCTAAAGCCAGTTTATATTTATT
TTTCGCGTGTTTTTCTGGTCTCAGTCTATGGAGTTTTCATAGAGATCAGCCGTGCACACAGAATTGGATAGGTCTATTAG
GTTGGTCATTTAGTTCTTTTCTACTTTATTTCTTTGGTGCCGCGGCATTTTTTATCCCTTTATATTTTCTTTGGTTATCT
TTTTTGTACTTCAGAAGGACTCCTCGACCGCTTTTCTTCTATAAAGCTGCGGCATTTCTTTCTCTCCCCTTTTGTTCTGC
GATTCTCTTATCCATGTTATCTCCAGTAGGAACGCTTCCTGCTTTATTAGATACACGTCTTCCAAAGTTTATTTTAGGGA
ATAATCCTCCTGTCTCTTATGTGGGTGGAATCCCTTTCTATCTGTTTTACGAAGGCCAATCTTTTTGTCTAAAACATTTA
ATTGGGTCTGTAGGAACTGCTCTAATTTTTGGATTCGTGATGCTATTCTCCGTCCTTTATCTTTGCGGAGGCATTGCTTT
ATTAAAAAAAAAAACCTTTCAAGACGGGGTCAAAAAGGCTTTTTGCTCTTTTTTCCAAACTTGTTTCAAAAATTTAAAAA
AATTAATAAATAGGCGAAACTATCTTCCTAAGCCTTCGGTTCCTTTTGTTTCCAAGAATCCTTTTTCTTGTACGAAATCG
CAACCTTCGCCACGTCGAGTTTCTGAGACTATCATTTTAGATGGGTCTATTTCTCCCTTACCTCAGGAAGAGATCCCCGG
TTCTAAGAAAGAGTCCTTTTTCCTAACTCCTCATCCTTGCAAGCGTTTCCTGACAAAATTTGTTGAGCCTCAAGAGAATA
AAGCGAAAGAAGGGAAAACAATTGCGCTATCTTCGACTCCCACTGTAGTGAGGGAATCCAAAGGCAAGGAAAGAGCGGCT
CTTCCTAAATTAAAAAGTTTAGCAGTCCCTGAAAATGATCTTCCGCAATATCATTTACTTAGTAAAAACAGAGAAGCTCG
TCCCGAGTCCTTACAAGCTGAGCTAGAGAGAAAAGCTCTGATTTTAAAACAGACTCTTACGAGTTTTGGAATTGATGCGG
ACCTTGGCAACATCTGTTCAGGACCGACATTAGCAGCTTTTGAAGTGTTACCTCATTCTGGAGTTAAGGTTCAGAAAATC
AAATCTTTAGAAAATGATATAGCTTTAAAACTCCAAGCTTCGAGCATACGGATTATTGCTCCGATTCCGGGGAAAGCTGC
TGTGGGTATTGAAATTCCCACACCTTTTCCTCAAGCTGTGAATTTTCGTGATTTATTAGAAGACTATCAGAAGACAAATC
GTAAATTGCAGATTCCCTTGTTGTTAGGGAAGAAAGCAAATGGTGACAATCTTTGGGCTGATTTAGCTACGATGCCTCAT
CTCATTATTGCTGGTACTACAGGATCTGGGAAATCTGTATGTATTAACACGATTGTCATGTCTATGATTATGACGACCTT
ACCTTCTGAAATTAAACTCGTCATTATTGATCCTAAAAAAGTAGAGCTCACTGGGTATTCGCAATTACCTCATATGTTAT
CTCCTGTGATTACCGAATCAAGAGAAGTGTACAATGCTTTAGTTTGGTTAGTTAAGGAAATGGAATCTCGTTATGAGATT
TTGAGATATTTGGGTTTGCGCAATATACAAGCGTTTAACTCCCGCACTCGCAATAAAACGATTGAGGCTTCTTACGACAG
GGAGATTCGTGAAACTATGCCCTTTATGGTAGGGATCATTGATGAGTTATCTGATTTGCTTCTCTCGTCATCCCAAGATA
TTGAAACTCCTATCATTCGCTTAGCTCAGATGGCTAGAGCTGTAGGGATTCATCTGATTTTAGCAACGCAACGCCCTTCA
AGAGAGGTAATTACAGGTTTAATTAAAGCAAATTTCCCCTCTCGAATTTCTTTTAAGGTCTCCAATAAAGTGAATAGTCA
GATTATCATTGATGAACCTGGTGCAGAGAATCTGATGGGAAATGGTGATATGCTTGTACTTCTTCCTTCTGTTTTTGGAA
CTATACGAGCTCAGGGTGCCTACATTTGTGATGAGGACATAAACAAAGTCATTCAAGATCTATGTTCTAGATTCCCTACA
CAATATGTGATTCCTTCTTTCCATGCTTTTGATGATTCTGATTCTGATAACTCTGGAGAAAAAGATCCTTTATTTGCTCA
GGCGAAAACCTTAATTTTACAGACGGGGAATGCTTCAACCACCTTCCTTCAAAGAAAATTAAAAATTGGTTATGCCCGAG
CAGCTAGTTTAATTGATCAACTTGAAGAAGCTAGAATTATTGGGCCTTCGGAAGGAGCTAAGCCTCGTCAAATCCTGATA
CAGAATCCTCTGGAAGGTTAG

Upstream 100 bases:

>100_bases
CCCGTCGTTCGCCCTCTTTATCTTCTTTGTTTCTTTTGTTTTTCTTGATATAACGAAATCTATAACGAAGCTCGACAATA
CTTAGAATCTTATGTAGCCC

Downstream 100 bases:

>100_bases
CATGCAAGGTTTTTTCCCTTTAGCTTCTGGATCCAAAGGGAATTCTGCTTATCTAGGCACGGATTCTTGTAAGATTCTTA
TTGATTTAGGAGTGAGCAAG

Product: cell division protein FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 806; Mature: 806

Protein sequence:

>806_residues
MIRERKKSRHPRLPTLPLAAKASLYLFFACFSGLSLWSFHRDQPCTQNWIGLLGWSFSSFLLYFFGAAAFFIPLYFLWLS
FLYFRRTPRPLFFYKAAAFLSLPFCSAILLSMLSPVGTLPALLDTRLPKFILGNNPPVSYVGGIPFYLFYEGQSFCLKHL
IGSVGTALIFGFVMLFSVLYLCGGIALLKKKTFQDGVKKAFCSFFQTCFKNLKKLINRRNYLPKPSVPFVSKNPFSCTKS
QPSPRRVSETIILDGSISPLPQEEIPGSKKESFFLTPHPCKRFLTKFVEPQENKAKEGKTIALSSTPTVVRESKGKERAA
LPKLKSLAVPENDLPQYHLLSKNREARPESLQAELERKALILKQTLTSFGIDADLGNICSGPTLAAFEVLPHSGVKVQKI
KSLENDIALKLQASSIRIIAPIPGKAAVGIEIPTPFPQAVNFRDLLEDYQKTNRKLQIPLLLGKKANGDNLWADLATMPH
LIIAGTTGSGKSVCINTIVMSMIMTTLPSEIKLVIIDPKKVELTGYSQLPHMLSPVITESREVYNALVWLVKEMESRYEI
LRYLGLRNIQAFNSRTRNKTIEASYDREIRETMPFMVGIIDELSDLLLSSSQDIETPIIRLAQMARAVGIHLILATQRPS
REVITGLIKANFPSRISFKVSNKVNSQIIIDEPGAENLMGNGDMLVLLPSVFGTIRAQGAYICDEDINKVIQDLCSRFPT
QYVIPSFHAFDDSDSDNSGEKDPLFAQAKTLILQTGNASTTFLQRKLKIGYARAASLIDQLEEARIIGPSEGAKPRQILI
QNPLEG

Sequences:

>Translated_806_residues
MIRERKKSRHPRLPTLPLAAKASLYLFFACFSGLSLWSFHRDQPCTQNWIGLLGWSFSSFLLYFFGAAAFFIPLYFLWLS
FLYFRRTPRPLFFYKAAAFLSLPFCSAILLSMLSPVGTLPALLDTRLPKFILGNNPPVSYVGGIPFYLFYEGQSFCLKHL
IGSVGTALIFGFVMLFSVLYLCGGIALLKKKTFQDGVKKAFCSFFQTCFKNLKKLINRRNYLPKPSVPFVSKNPFSCTKS
QPSPRRVSETIILDGSISPLPQEEIPGSKKESFFLTPHPCKRFLTKFVEPQENKAKEGKTIALSSTPTVVRESKGKERAA
LPKLKSLAVPENDLPQYHLLSKNREARPESLQAELERKALILKQTLTSFGIDADLGNICSGPTLAAFEVLPHSGVKVQKI
KSLENDIALKLQASSIRIIAPIPGKAAVGIEIPTPFPQAVNFRDLLEDYQKTNRKLQIPLLLGKKANGDNLWADLATMPH
LIIAGTTGSGKSVCINTIVMSMIMTTLPSEIKLVIIDPKKVELTGYSQLPHMLSPVITESREVYNALVWLVKEMESRYEI
LRYLGLRNIQAFNSRTRNKTIEASYDREIRETMPFMVGIIDELSDLLLSSSQDIETPIIRLAQMARAVGIHLILATQRPS
REVITGLIKANFPSRISFKVSNKVNSQIIIDEPGAENLMGNGDMLVLLPSVFGTIRAQGAYICDEDINKVIQDLCSRFPT
QYVIPSFHAFDDSDSDNSGEKDPLFAQAKTLILQTGNASTTFLQRKLKIGYARAASLIDQLEEARIIGPSEGAKPRQILI
QNPLEG
>Mature_806_residues
MIRERKKSRHPRLPTLPLAAKASLYLFFACFSGLSLWSFHRDQPCTQNWIGLLGWSFSSFLLYFFGAAAFFIPLYFLWLS
FLYFRRTPRPLFFYKAAAFLSLPFCSAILLSMLSPVGTLPALLDTRLPKFILGNNPPVSYVGGIPFYLFYEGQSFCLKHL
IGSVGTALIFGFVMLFSVLYLCGGIALLKKKTFQDGVKKAFCSFFQTCFKNLKKLINRRNYLPKPSVPFVSKNPFSCTKS
QPSPRRVSETIILDGSISPLPQEEIPGSKKESFFLTPHPCKRFLTKFVEPQENKAKEGKTIALSSTPTVVRESKGKERAA
LPKLKSLAVPENDLPQYHLLSKNREARPESLQAELERKALILKQTLTSFGIDADLGNICSGPTLAAFEVLPHSGVKVQKI
KSLENDIALKLQASSIRIIAPIPGKAAVGIEIPTPFPQAVNFRDLLEDYQKTNRKLQIPLLLGKKANGDNLWADLATMPH
LIIAGTTGSGKSVCINTIVMSMIMTTLPSEIKLVIIDPKKVELTGYSQLPHMLSPVITESREVYNALVWLVKEMESRYEI
LRYLGLRNIQAFNSRTRNKTIEASYDREIRETMPFMVGIIDELSDLLLSSSQDIETPIIRLAQMARAVGIHLILATQRPS
REVITGLIKANFPSRISFKVSNKVNSQIIIDEPGAENLMGNGDMLVLLPSVFGTIRAQGAYICDEDINKVIQDLCSRFPT
QYVIPSFHAFDDSDSDNSGEKDPLFAQAKTLILQTGNASTTFLQRKLKIGYARAASLIDQLEEARIIGPSEGAKPRQILI
QNPLEG

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=478, Percent_Identity=38.9121338912134, Blast_Score=345, Evalue=5e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_CHLPN (Q9Z726)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   F72024
- PIR:   F86600
- RefSeq:   NP_225075.1
- RefSeq:   NP_300937.1
- RefSeq:   NP_445526.1
- RefSeq:   NP_877181.1
- ProteinModelPortal:   Q9Z726
- SMR:   Q9Z726
- GeneID:   1467588
- GeneID:   895252
- GeneID:   919643
- GeneID:   963460
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0989
- KEGG:   cpn:CPn0880
- KEGG:   cpt:CpB0909
- TIGR:   CP_0989
- HOGENOM:   HBG662140
- OMA:   WADLATM
- ProtClustDB:   CLSK871572
- BioCyc:   CPNE115711:CP_0989-MONOMER
- BioCyc:   CPNE115713:CPN0880-MONOMER
- BioCyc:   CPNE138677:CPJ0880-MONOMER
- BioCyc:   CPNE182082:CPB0909-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 89887; Mature: 89887

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcb7ec0c)-; HASH(0xd5e5168)-; HASH(0xd46a748)-; HASH(0xd46a694)-; HASH(0xaf9f010)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRERKKSRHPRLPTLPLAAKASLYLFFACFSGLSLWSFHRDQPCTQNWIGLLGWSFSSF
CCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LLYFFGAAAFFIPLYFLWLSFLYFRRTPRPLFFYKAAAFLSLPFCSAILLSMLSPVGTLP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ALLDTRLPKFILGNNPPVSYVGGIPFYLFYEGQSFCLKHLIGSVGTALIFGFVMLFSVLY
HHHHHCCCHHEECCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGGIALLKKKTFQDGVKKAFCSFFQTCFKNLKKLINRRNYLPKPSVPFVSKNPFSCTKS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
QPSPRRVSETIILDGSISPLPQEEIPGSKKESFFLTPHPCKRFLTKFVEPQENKAKEGKT
CCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCE
IALSSTPTVVRESKGKERAALPKLKSLAVPENDLPQYHLLSKNREARPESLQAELERKAL
EEECCCCHHHHHCCCCHHHHCCHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHH
ILKQTLTSFGIDADLGNICSGPTLAAFEVLPHSGVKVQKIKSLENDIALKLQASSIRIIA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCEEEEE
PIPGKAAVGIEIPTPFPQAVNFRDLLEDYQKTNRKLQIPLLLGKKANGDNLWADLATMPH
ECCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHCCCE
LIIAGTTGSGKSVCINTIVMSMIMTTLPSEIKLVIIDPKKVELTGYSQLPHMLSPVITES
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHH
REVYNALVWLVKEMESRYEILRYLGLRNIQAFNSRTRNKTIEASYDREIRETMPFMVGII
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DELSDLLLSSSQDIETPIIRLAQMARAVGIHLILATQRPSREVITGLIKANFPSRISFKV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEE
SNKVNSQIIIDEPGAENLMGNGDMLVLLPSVFGTIRAQGAYICDEDINKVIQDLCSRFPT
CCCCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHCCCCEECHHHHHHHHHHHHHHCCC
QYVIPSFHAFDDSDSDNSGEKDPLFAQAKTLILQTGNASTTFLQRKLKIGYARAASLIDQ
CEECCCCCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LEEARIIGPSEGAKPRQILIQNPLEG
HHHCEEECCCCCCCCCEEEECCCCCH
>Mature Secondary Structure
MIRERKKSRHPRLPTLPLAAKASLYLFFACFSGLSLWSFHRDQPCTQNWIGLLGWSFSSF
CCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LLYFFGAAAFFIPLYFLWLSFLYFRRTPRPLFFYKAAAFLSLPFCSAILLSMLSPVGTLP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ALLDTRLPKFILGNNPPVSYVGGIPFYLFYEGQSFCLKHLIGSVGTALIFGFVMLFSVLY
HHHHHCCCHHEECCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGGIALLKKKTFQDGVKKAFCSFFQTCFKNLKKLINRRNYLPKPSVPFVSKNPFSCTKS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
QPSPRRVSETIILDGSISPLPQEEIPGSKKESFFLTPHPCKRFLTKFVEPQENKAKEGKT
CCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCE
IALSSTPTVVRESKGKERAALPKLKSLAVPENDLPQYHLLSKNREARPESLQAELERKAL
EEECCCCHHHHHCCCCHHHHCCHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHH
ILKQTLTSFGIDADLGNICSGPTLAAFEVLPHSGVKVQKIKSLENDIALKLQASSIRIIA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCEEEEE
PIPGKAAVGIEIPTPFPQAVNFRDLLEDYQKTNRKLQIPLLLGKKANGDNLWADLATMPH
ECCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHCCCE
LIIAGTTGSGKSVCINTIVMSMIMTTLPSEIKLVIIDPKKVELTGYSQLPHMLSPVITES
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHH
REVYNALVWLVKEMESRYEILRYLGLRNIQAFNSRTRNKTIEASYDREIRETMPFMVGII
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DELSDLLLSSSQDIETPIIRLAQMARAVGIHLILATQRPSREVITGLIKANFPSRISFKV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEE
SNKVNSQIIIDEPGAENLMGNGDMLVLLPSVFGTIRAQGAYICDEDINKVIQDLCSRFPT
CCCCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHCCCCEECHHHHHHHHHHHHHHCCC
QYVIPSFHAFDDSDSDNSGEKDPLFAQAKTLILQTGNASTTFLQRKLKIGYARAASLIDQ
CEECCCCCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LEEARIIGPSEGAKPRQILIQNPLEG
HHHCEEECCCCCCCCCEEEECCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362; 11500413