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The map label for this gene is clpX

Identifier: 15618755

GI number: 15618755

Start: 958109

End: 959374

Strand: Reverse

Name: clpX

Synonym: CPn0846

Alternate gene names: 15618755

Gene position: 959374-958109 (Counterclockwise)

Preceding gene: 15618756

Following gene: 15618754

Centisome position: 77.98

GC content: 40.28

Gene sequence:

>1266_bases
ATGAATAAAAAAAATCTAACTATTTGTTCATTTTGCGGTCGGTCTGAAAAAGATGTAGAGAAACTGATTGCTGGGCCTTC
GGTATACATTTGTGACTACTGCATCAAATTATGCTCTGGAATTTTAGATAAGAAACCCTCCTCTACAATATCCTCAGCTC
CAGTTTCTGAAACACCTTCACAGCCTTCTGATCTCAGGGTGCTTACCCCTAAGGAAATCAAAAAGCATATTGATGAATAT
GTCATTGGTCAGGAAAGAGCTAAAAAGACAATCGCTGTTGCTGTTTATAATCACTATAAACGTATACGTGCTCTACTACA
TAACAAACAGGTAAGCTACGGGAAATCTAACGTGCTTCTCCTAGGCCCTACAGGATCTGGAAAAACATTAATTGCAAAAA
CATTGGCAAAAATTTTAGATGTTCCCTTCACCATAGCCGACGCAACGACCCTAACGGAAGCAGGTTATGTCGGTGAAGAT
GTAGAGAACATTGTCTTACGTTTATTACAAGCTGCTGATTACGATGTCGCCCGTGCAGAACGAGGCATTATCTATATCGA
TGAAATCGATAAAATTGGAAGGACAACAGCAAACGTCTCCATTACTAGAGATGTTTCTGGCGAAGGGGTTCAACAAGCAT
TGTTAAAAATCGTTGAAGGAACCACAGCAAACGTTCCTCCTAAAGGAGGACGTAAGCATCCTAACCAAGAGTATATCCGA
GTCAATACGGAAAATATCTTATTTATCGTAGGCGGAGCCTTCGTCAACCTAGATAAGATTATCGCAAAGCGATTGGGGAA
AACTACCATAGGGTTTTCTGATGATCAAGCAGACCTCTCTCAAAAAACCAGAGACCATCTACTTGCTAAAGTTGAAACCG
AAGACCTGATTGCCTTCGGAATGATCCCTGAATTTGTCGGAAGATTCAACTGCATTGTAAACTGTGAAGAGCTTTCTTTG
GATGAGCTTGTAGCCATCCTTACAGAACCTACAAATGCGATTGTGAAACAATATATGGAGCTATTCGCAGAAGAAAACGT
CAAGTTAGTCTTCAAAAAAGAAGCCCTATATGCTATAGCAAAAAAAGCCAAGCAAGCAAAAACTGGAGCTCGTGCTCTAG
GGATGATCCTAGAAAATCTCCTTAGAGACCTTATGTTTGAAATTCCTTCAGATCCTACAGTAGAAGCTATTCATATCCAA
GAAGACACTATCGCAGAAAATAAAGCGCCAATAATTATCAGAAGGACCCCAGAAGCTATCGCTTAG

Upstream 100 bases:

>100_bases
CATGGGAGCCGAGGAAGCCATCTCCTACGGACTTATTGATAAGGTGGTAACTTCTGCGAAAGAAACTAATAAGGATACAA
GTAGCACTTAGAGAGAACAT

Downstream 100 bases:

>100_bases
CTCTTTTTAGTTCCTATTTTAGGGGTGTCATGACAACAATTGCCATAGAAGCTGCAAAAAAAGTTCTTATCAAACTACGT
AATGCAGGATATCAGGCATA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MNKKNLTICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKKPSSTISSAPVSETPSQPSDLRVLTPKEIKKHIDEY
VIGQERAKKTIAVAVYNHYKRIRALLHNKQVSYGKSNVLLLGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGED
VENIVLRLLQAADYDVARAERGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIVEGTTANVPPKGGRKHPNQEYIR
VNTENILFIVGGAFVNLDKIIAKRLGKTTIGFSDDQADLSQKTRDHLLAKVETEDLIAFGMIPEFVGRFNCIVNCEELSL
DELVAILTEPTNAIVKQYMELFAEENVKLVFKKEALYAIAKKAKQAKTGARALGMILENLLRDLMFEIPSDPTVEAIHIQ
EDTIAENKAPIIIRRTPEAIA

Sequences:

>Translated_421_residues
MNKKNLTICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKKPSSTISSAPVSETPSQPSDLRVLTPKEIKKHIDEY
VIGQERAKKTIAVAVYNHYKRIRALLHNKQVSYGKSNVLLLGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGED
VENIVLRLLQAADYDVARAERGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIVEGTTANVPPKGGRKHPNQEYIR
VNTENILFIVGGAFVNLDKIIAKRLGKTTIGFSDDQADLSQKTRDHLLAKVETEDLIAFGMIPEFVGRFNCIVNCEELSL
DELVAILTEPTNAIVKQYMELFAEENVKLVFKKEALYAIAKKAKQAKTGARALGMILENLLRDLMFEIPSDPTVEAIHIQ
EDTIAENKAPIIIRRTPEAIA
>Mature_421_residues
MNKKNLTICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKKPSSTISSAPVSETPSQPSDLRVLTPKEIKKHIDEY
VIGQERAKKTIAVAVYNHYKRIRALLHNKQVSYGKSNVLLLGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGED
VENIVLRLLQAADYDVARAERGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIVEGTTANVPPKGGRKHPNQEYIR
VNTENILFIVGGAFVNLDKIIAKRLGKTTIGFSDDQADLSQKTRDHLLAKVETEDLIAFGMIPEFVGRFNCIVNCEELSL
DELVAILTEPTNAIVKQYMELFAEENVKLVFKKEALYAIAKKAKQAKTGARALGMILENLLRDLMFEIPSDPTVEAIHIQ
EDTIAENKAPIIIRRTPEAIA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=324, Percent_Identity=47.5308641975309, Blast_Score=281, Evalue=1e-75,
Organism=Escherichia coli, GI1786642, Length=416, Percent_Identity=57.4519230769231, Blast_Score=463, Evalue=1e-132,
Organism=Escherichia coli, GI1790366, Length=107, Percent_Identity=41.1214953271028, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=333, Percent_Identity=44.1441441441441, Blast_Score=264, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=333, Percent_Identity=44.1441441441441, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=436, Percent_Identity=35.5504587155963, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=276, Percent_Identity=37.3188405797101, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=432, Percent_Identity=37.962962962963, Blast_Score=249, Evalue=5e-67,
Organism=Drosophila melanogaster, GI24648291, Length=311, Percent_Identity=47.2668810289389, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24648289, Length=311, Percent_Identity=47.2668810289389, Blast_Score=285, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46352; Mature: 46352

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKNLTICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKKPSSTISSAPVSETPS
CCCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QPSDLRVLTPKEIKKHIDEYVIGQERAKKTIAVAVYNHYKRIRALLHNKQVSYGKSNVLL
CCCCEEEECHHHHHHHHHHHHHCHHHHHHEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDVENIVLRLLQAADYDVARAE
ECCCCCCCHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHC
RGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIVEGTTANVPPKGGRKHPNQEYIR
CCEEEEECHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
VNTENILFIVGGAFVNLDKIIAKRLGKTTIGFSDDQADLSQKTRDHLLAKVETEDLIAFG
EECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
MIPEFVGRFNCIVNCEELSLDELVAILTEPTNAIVKQYMELFAEENVKLVFKKEALYAIA
HHHHHHHHHHEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
KKAKQAKTGARALGMILENLLRDLMFEIPSDPTVEAIHIQEDTIAENKAPIIIRRTPEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCCCCEEEECCCCCC
A
C
>Mature Secondary Structure
MNKKNLTICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKKPSSTISSAPVSETPS
CCCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QPSDLRVLTPKEIKKHIDEYVIGQERAKKTIAVAVYNHYKRIRALLHNKQVSYGKSNVLL
CCCCEEEECHHHHHHHHHHHHHCHHHHHHEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDVENIVLRLLQAADYDVARAE
ECCCCCCCHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHC
RGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIVEGTTANVPPKGGRKHPNQEYIR
CCEEEEECHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
VNTENILFIVGGAFVNLDKIIAKRLGKTTIGFSDDQADLSQKTRDHLLAKVETEDLIAFG
EECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
MIPEFVGRFNCIVNCEELSLDELVAILTEPTNAIVKQYMELFAEENVKLVFKKEALYAIA
HHHHHHHHHHEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
KKAKQAKTGARALGMILENLLRDLMFEIPSDPTVEAIHIQEDTIAENKAPIIIRRTPEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCCCCEEEECCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA