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The map label for this gene is engA

Identifier: 15618753

GI number: 15618753

Start: 955267

End: 956730

Strand: Reverse

Name: engA

Synonym: CPn0844

Alternate gene names: 15618753

Gene position: 956730-955267 (Counterclockwise)

Preceding gene: 15618754

Following gene: 15618747

Centisome position: 77.77

GC content: 39.07

Gene sequence:

>1464_bases
ATGCTAAAAATAGCCATCTTAGGAAGACCCAATGTAGGAAAGTCATCACTTTTCAATCGTCTATGTAAACGCTCTTTAGC
AATTGTAAATTCTCAAGAGGGGACAACTCGAGATCGCCTCTACGGCGAGCTCCATGCGTTTGGTGTTCCTGCTCAGGTCA
TCGATACTGGAGGTGTTGATCACAATTCTGAAGATTACTTCCAAAAGCATATCTATAACCAAGCCCTCACCGGCGCTAAG
GAAGCTGATGTCCTATTGCTAGTCATTGATATCCGCTGTGGTATTACCGAAGAAGATGCTCACCTAGCCAAACTCCTCCT
TCCCTTAAAGAAACCTCTCATCCTTGTCGCCAATAAAGCAGACAGTCGCCAAGAGGAATTACAAATTCATGAGACCTATA
AATTAGGAATTCGAGATATTGTAGTGACCTCAACAGCTCACGATAAGCACATTGATACCCTTCTTCAAAGAATTAAGTTG
GTAGCCAACCTACCAGAACCTCGCGAAGAAGAAGAAGAAGGCCTTGAGGAGCTTTCTGTAGATGAACACGAAGAATCTGA
GGCGGCTCTCCCTTCAAATACATTCCCTGATTTTTCAGAAGTATTCACGGAAGGCTTCTCCCCTGAAGAACCCTGCACTA
TCCCAGAGTCTCCTCAGCAAGCTCCCAAGACATTAAAAATAGCGCTCATCGGACGTCCTAACGTAGGGAAATCTTCTATT
ATTAACGGTCTTCTCAATGAAGAGCGTTGTATTATTGATAATACTCCTGGGACAACACGTGATAATATCGATATTCTGTA
TTCCCATAAGGACCGCCAGTATCTTTTCATTGATACTGCGGGTCTTAGAAAAATGAAAAGCGTTAAGAATTCCATAGAAT
GGATTTCTTCATCTCGAACTGAAAAAGCTATTTCTCGTGCTGATATCTGTCTTCTTGTGATTGATGCTACACAAAAACTC
TCTTCTTATGAGAAGCGCATCCTCTCTTTAATTTCTAAACGAAAAAAGCCTCACATCATATTAATTAACAAATGGGATTT
ACTTGAAGAAGTCCGCATGGAGCATTACTGCAAAGATCTACGCGCTACTGATCCTTATTTAGGACAAGCTAAAATGCTTT
GTATCTCTGCTACTACGAAACGCAATCTTAAAAAGATCTTCTCTGCAATTGATGAACTACATCACGTAGTATCGAATAAA
GTTCCAACACCGATAGTAAATAAAACTCTTGCTTCTGCTCTACATAGAAACCATCCTCAGGTGATTCAAGGACGCAGGTT
GAGGATCTATTATGCAATCCAAAAGACAACGACACCTCTGCAGTTTTTATTATTTATAAATGCAAAGTCTCTATTAACAA
AACATTATGAATATTATTTAAAAAACACATTAAAATCGTCGTTTAATTTATATGGAATACCTTTCGATTTAGAATTTAAA
GAAAAACCAAAAAGACATAATTAA

Upstream 100 bases:

>100_bases
TCCTACTTTTACAACCCTTAGAAATTTATCTCTTTAGCTTTAATTTTTTAACTCCTATTATTTTCTCATTAATTACTGAA
AAAATAGAATAGAGACGATT

Downstream 100 bases:

>100_bases
TTTGTTAAAAAATAATAAAAAATATTATTACCATGAAATAAAAATAAATTAATTATTTCTTGGAGATTTAAAGTCATGAA
CTATGACCAATACGATACGC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MLKIAILGRPNVGKSSLFNRLCKRSLAIVNSQEGTTRDRLYGELHAFGVPAQVIDTGGVDHNSEDYFQKHIYNQALTGAK
EADVLLLVIDIRCGITEEDAHLAKLLLPLKKPLILVANKADSRQEELQIHETYKLGIRDIVVTSTAHDKHIDTLLQRIKL
VANLPEPREEEEEGLEELSVDEHEESEAALPSNTFPDFSEVFTEGFSPEEPCTIPESPQQAPKTLKIALIGRPNVGKSSI
INGLLNEERCIIDNTPGTTRDNIDILYSHKDRQYLFIDTAGLRKMKSVKNSIEWISSSRTEKAISRADICLLVIDATQKL
SSYEKRILSLISKRKKPHIILINKWDLLEEVRMEHYCKDLRATDPYLGQAKMLCISATTKRNLKKIFSAIDELHHVVSNK
VPTPIVNKTLASALHRNHPQVIQGRRLRIYYAIQKTTTPLQFLLFINAKSLLTKHYEYYLKNTLKSSFNLYGIPFDLEFK
EKPKRHN

Sequences:

>Translated_487_residues
MLKIAILGRPNVGKSSLFNRLCKRSLAIVNSQEGTTRDRLYGELHAFGVPAQVIDTGGVDHNSEDYFQKHIYNQALTGAK
EADVLLLVIDIRCGITEEDAHLAKLLLPLKKPLILVANKADSRQEELQIHETYKLGIRDIVVTSTAHDKHIDTLLQRIKL
VANLPEPREEEEEGLEELSVDEHEESEAALPSNTFPDFSEVFTEGFSPEEPCTIPESPQQAPKTLKIALIGRPNVGKSSI
INGLLNEERCIIDNTPGTTRDNIDILYSHKDRQYLFIDTAGLRKMKSVKNSIEWISSSRTEKAISRADICLLVIDATQKL
SSYEKRILSLISKRKKPHIILINKWDLLEEVRMEHYCKDLRATDPYLGQAKMLCISATTKRNLKKIFSAIDELHHVVSNK
VPTPIVNKTLASALHRNHPQVIQGRRLRIYYAIQKTTTPLQFLLFINAKSLLTKHYEYYLKNTLKSSFNLYGIPFDLEFK
EKPKRHN
>Mature_487_residues
MLKIAILGRPNVGKSSLFNRLCKRSLAIVNSQEGTTRDRLYGELHAFGVPAQVIDTGGVDHNSEDYFQKHIYNQALTGAK
EADVLLLVIDIRCGITEEDAHLAKLLLPLKKPLILVANKADSRQEELQIHETYKLGIRDIVVTSTAHDKHIDTLLQRIKL
VANLPEPREEEEEGLEELSVDEHEESEAALPSNTFPDFSEVFTEGFSPEEPCTIPESPQQAPKTLKIALIGRPNVGKSSI
INGLLNEERCIIDNTPGTTRDNIDILYSHKDRQYLFIDTAGLRKMKSVKNSIEWISSSRTEKAISRADICLLVIDATQKL
SSYEKRILSLISKRKKPHIILINKWDLLEEVRMEHYCKDLRATDPYLGQAKMLCISATTKRNLKKIFSAIDELHHVVSNK
VPTPIVNKTLASALHRNHPQVIQGRRLRIYYAIQKTTTPLQFLLFINAKSLLTKHYEYYLKNTLKSSFNLYGIPFDLEFK
EKPKRHN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=478, Percent_Identity=32.8451882845188, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI2367268, Length=137, Percent_Identity=37.956204379562, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788919, Length=169, Percent_Identity=29.585798816568, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=135, Percent_Identity=34.0740740740741, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=170, Percent_Identity=33.5294117647059, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI45550813, Length=139, Percent_Identity=36.6906474820144, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_CHLPN (Q9Z762)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   B86596
- PIR:   D72028
- RefSeq:   NP_225039.1
- RefSeq:   NP_300901.1
- RefSeq:   NP_445562.1
- RefSeq:   NP_877145.1
- ProteinModelPortal:   Q9Z762
- SMR:   Q9Z762
- GeneID:   1467552
- GeneID:   894852
- GeneID:   919606
- GeneID:   963502
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP1025
- KEGG:   cpn:CPn0844
- KEGG:   cpt:CpB0873
- TIGR:   CP_1025
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   CPNE115711:CP_1025-MONOMER
- BioCyc:   CPNE115713:CPN0844-MONOMER
- BioCyc:   CPNE138677:CPJ0844-MONOMER
- BioCyc:   CPNE182082:CPB0873-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 55372; Mature: 55372

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIAILGRPNVGKSSLFNRLCKRSLAIVNSQEGTTRDRLYGELHAFGVPAQVIDTGGVD
CEEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCHHHHCCCCCC
HNSEDYFQKHIYNQALTGAKEADVLLLVIDIRCGITEEDAHLAKLLLPLKKPLILVANKA
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCC
DSRQEELQIHETYKLGIRDIVVTSTAHDKHIDTLLQRIKLVANLPEPREEEEEGLEELSV
CCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
DEHEESEAALPSNTFPDFSEVFTEGFSPEEPCTIPESPQQAPKTLKIALIGRPNVGKSSI
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHH
INGLLNEERCIIDNTPGTTRDNIDILYSHKDRQYLFIDTAGLRKMKSVKNSIEWISSSRT
HHHHCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHCCHH
EKAISRADICLLVIDATQKLSSYEKRILSLISKRKKPHIILINKWDLLEEVRMEHYCKDL
HHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHH
RATDPYLGQAKMLCISATTKRNLKKIFSAIDELHHVVSNKVPTPIVNKTLASALHRNHPQ
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCH
VIQGRRLRIYYAIQKTTTPLQFLLFINAKSLLTKHYEYYLKNTLKSSFNLYGIPFDLEFK
HHCCCEEEEEEEEECCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCCC
EKPKRHN
CCCCCCC
>Mature Secondary Structure
MLKIAILGRPNVGKSSLFNRLCKRSLAIVNSQEGTTRDRLYGELHAFGVPAQVIDTGGVD
CEEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCHHHHCCCCCC
HNSEDYFQKHIYNQALTGAKEADVLLLVIDIRCGITEEDAHLAKLLLPLKKPLILVANKA
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCC
DSRQEELQIHETYKLGIRDIVVTSTAHDKHIDTLLQRIKLVANLPEPREEEEEGLEELSV
CCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
DEHEESEAALPSNTFPDFSEVFTEGFSPEEPCTIPESPQQAPKTLKIALIGRPNVGKSSI
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHH
INGLLNEERCIIDNTPGTTRDNIDILYSHKDRQYLFIDTAGLRKMKSVKNSIEWISSSRT
HHHHCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHCCHH
EKAISRADICLLVIDATQKLSSYEKRILSLISKRKKPHIILINKWDLLEEVRMEHYCKDL
HHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHH
RATDPYLGQAKMLCISATTKRNLKKIFSAIDELHHVVSNKVPTPIVNKTLASALHRNHPQ
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCH
VIQGRRLRIYYAIQKTTTPLQFLLFINAKSLLTKHYEYYLKNTLKSSFNLYGIPFDLEFK
HHCCCEEEEEEEEECCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCCC
EKPKRHN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362