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The map label for this gene is trpS

Identifier: 15618711

GI number: 15618711

Start: 908706

End: 909740

Strand: Reverse

Name: trpS

Synonym: CPn0802

Alternate gene names: 15618711

Gene position: 909740-908706 (Counterclockwise)

Preceding gene: 15618712

Following gene: 15618710

Centisome position: 73.95

GC content: 43.0

Gene sequence:

>1035_bases
ATGAATAAAAAAAAGCGCGTACTTACCGGGGATCGTCCCACAGGGAAACTCCATTTAGGGCATTGGGTTGGTTCTATAAA
AAACCGATTAGAACTTCAAAATAGCCCTGAGTACGATTGCTTTTTTATTATTGCCGATCTCCACACCCTAACTACAAAAA
TCCGCAAGGAAGAGGTTTTAGATGTAGATAACCACATCTATGAAGTTCTTGCTGATTGGCTAAGTGTAGGGATTGATCCA
ACGAAATCTATAATTTACCTACAATCTGCGATCCCTGAGATCTACGAGTTACATCTCCTATTTTCGATGCTCATCTCAAT
CAATAGAGTGATGGGCATTCCCAGCCTCAAAGATATGGCCCGAAATGCCTCAATCGAGGAGGGAAGTCTTTCTTATGGTC
TTATTGGGTACCCTATTTTACAAAGTGCGGATATTCTTCTAGCGAAAGCACAGTTTGTCCCTGTAGGGAAAGACAATGAA
GCGCATGTGGAGCTCACCCGGGATATCGCTAGAAATTTCAACCGTCTGTATGGGCAGGTATTTCCAGAGCCCGAGGTACT
ACAAGGCGAGCTTACCTCTCTTGTAGGAATTGACGGGCAAGGGAAAATGAGCAAGTCCGCGAACAACGCGATCTATCTTT
CCGATAGCGACGCTACAATTACTGAGAAAGTCCGTAAGATGTACACGGATCCCAACCGGATTCGAGCAACCACACCAGGT
CGAGTTGAAGGAAATCCCCTCTTTATTTATCATGACATCTTCAATCCCCATAAAGATGAGGTTGAAGAGTTTAAAGCACG
CTATCGTCAAGGTTGCATTAAAGACATCGAAGTAAAAGCACGCCTTGCTGAAGAGCTGATTCACTTTTTAAAACCCATAA
AAGAAAGACGCTCAGAATTTCTATCCAAGCCTCTGGCATTACAAAACGTCTTAGAGGATGGCACGCATAAAATGCGTGAA
GTAGCCAAAGTCACTATGGAAGAAGTTCATGACAAATTTGGGTTTAGCCATAAATGGCGCTCATTGCTTAAATAA

Upstream 100 bases:

>100_bases
ATCCTGTTGGAGAGAAAAATCTTCAGGAAATTCAAGAAGAAATTACATCATTAAAAAATCACTTTGATGAGCTAACTAAA
GCACTTCAATAGCGGACGTC

Downstream 100 bases:

>100_bases
TTTTTACTATGACATTCCAACTTCATGCTCCTTTTGCTCCTTGCGGCGACCAGCCAGAGGCGATTGCTCGGCTGTCTGCG
GGTGTGCGTAATCAGGTAAA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNKKKRVLTGDRPTGKLHLGHWVGSIKNRLELQNSPEYDCFFIIADLHTLTTKIRKEEVLDVDNHIYEVLADWLSVGIDP
TKSIIYLQSAIPEIYELHLLFSMLISINRVMGIPSLKDMARNASIEEGSLSYGLIGYPILQSADILLAKAQFVPVGKDNE
AHVELTRDIARNFNRLYGQVFPEPEVLQGELTSLVGIDGQGKMSKSANNAIYLSDSDATITEKVRKMYTDPNRIRATTPG
RVEGNPLFIYHDIFNPHKDEVEEFKARYRQGCIKDIEVKARLAEELIHFLKPIKERRSEFLSKPLALQNVLEDGTHKMRE
VAKVTMEEVHDKFGFSHKWRSLLK

Sequences:

>Translated_344_residues
MNKKKRVLTGDRPTGKLHLGHWVGSIKNRLELQNSPEYDCFFIIADLHTLTTKIRKEEVLDVDNHIYEVLADWLSVGIDP
TKSIIYLQSAIPEIYELHLLFSMLISINRVMGIPSLKDMARNASIEEGSLSYGLIGYPILQSADILLAKAQFVPVGKDNE
AHVELTRDIARNFNRLYGQVFPEPEVLQGELTSLVGIDGQGKMSKSANNAIYLSDSDATITEKVRKMYTDPNRIRATTPG
RVEGNPLFIYHDIFNPHKDEVEEFKARYRQGCIKDIEVKARLAEELIHFLKPIKERRSEFLSKPLALQNVLEDGTHKMRE
VAKVTMEEVHDKFGFSHKWRSLLK
>Mature_344_residues
MNKKKRVLTGDRPTGKLHLGHWVGSIKNRLELQNSPEYDCFFIIADLHTLTTKIRKEEVLDVDNHIYEVLADWLSVGIDP
TKSIIYLQSAIPEIYELHLLFSMLISINRVMGIPSLKDMARNASIEEGSLSYGLIGYPILQSADILLAKAQFVPVGKDNE
AHVELTRDIARNFNRLYGQVFPEPEVLQGELTSLVGIDGQGKMSKSANNAIYLSDSDATITEKVRKMYTDPNRIRATTPG
RVEGNPLFIYHDIFNPHKDEVEEFKARYRQGCIKDIEVKARLAEELIHFLKPIKERRSEFLSKPLALQNVLEDGTHKMRE
VAKVTMEEVHDKFGFSHKWRSLLK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI7710154, Length=344, Percent_Identity=31.9767441860465, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI41352700, Length=189, Percent_Identity=37.5661375661376, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1789786, Length=342, Percent_Identity=29.8245614035088, Blast_Score=151, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71982800, Length=338, Percent_Identity=28.698224852071, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71982793, Length=338, Percent_Identity=28.698224852071, Blast_Score=134, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6320474, Length=357, Percent_Identity=30.5322128851541, Blast_Score=149, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24666151, Length=339, Percent_Identity=32.1533923303835, Blast_Score=162, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYW_CHLPN (Q9Z7A4)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C72034
- PIR:   H86590
- RefSeq:   NP_224997.1
- RefSeq:   NP_300859.1
- RefSeq:   NP_445606.1
- RefSeq:   NP_877103.1
- ProteinModelPortal:   Q9Z7A4
- SMR:   Q9Z7A4
- GeneID:   1467510
- GeneID:   895541
- GeneID:   919559
- GeneID:   963553
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP1069
- KEGG:   cpn:CPn0802
- KEGG:   cpt:CpB0831
- TIGR:   CP_1069
- HOGENOM:   HBG293263
- OMA:   DNESHIE
- PhylomeDB:   Q9Z7A4
- ProtClustDB:   PRK00927
- BioCyc:   CPNE115711:CP_1069-MONOMER
- BioCyc:   CPNE115713:CPN0802-MONOMER
- BioCyc:   CPNE138677:CPJ0802-MONOMER
- BioCyc:   CPNE182082:CPB0831-MONOMER
- BRENDA:   6.1.1.2
- GO:   GO:0005737
- HAMAP:   MF_00140_B
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10055
- PRINTS:   PR01039
- TIGRFAMs:   TIGR00233

Pfam domain/function: PF00579 tRNA-synt_1b

EC number: =6.1.1.2

Molecular weight: Translated: 39284; Mature: 39284

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 205-205

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKKRVLTGDRPTGKLHLGHWVGSIKNRLELQNSPEYDCFFIIADLHTLTTKIRKEEVL
CCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
DVDNHIYEVLADWLSVGIDPTKSIIYLQSAIPEIYELHLLFSMLISINRVMGIPSLKDMA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RNASIEEGSLSYGLIGYPILQSADILLAKAQFVPVGKDNEAHVELTRDIARNFNRLYGQV
HCCCCCCCCCCCCEECCHHHHCCHHEEEHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
FPEPEVLQGELTSLVGIDGQGKMSKSANNAIYLSDSDATITEKVRKMYTDPNRIRATTPG
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEECCCC
RVEGNPLFIYHDIFNPHKDEVEEFKARYRQGCIKDIEVKARLAEELIHFLKPIKERRSEF
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKPLALQNVLEDGTHKMREVAKVTMEEVHDKFGFSHKWRSLLK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure
MNKKKRVLTGDRPTGKLHLGHWVGSIKNRLELQNSPEYDCFFIIADLHTLTTKIRKEEVL
CCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
DVDNHIYEVLADWLSVGIDPTKSIIYLQSAIPEIYELHLLFSMLISINRVMGIPSLKDMA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RNASIEEGSLSYGLIGYPILQSADILLAKAQFVPVGKDNEAHVELTRDIARNFNRLYGQV
HCCCCCCCCCCCCEECCHHHHCCHHEEEHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
FPEPEVLQGELTSLVGIDGQGKMSKSANNAIYLSDSDATITEKVRKMYTDPNRIRATTPG
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEECCCC
RVEGNPLFIYHDIFNPHKDEVEEFKARYRQGCIKDIEVKARLAEELIHFLKPIKERRSEF
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKPLALQNVLEDGTHKMREVAKVTMEEVHDKFGFSHKWRSLLK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362