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The map label for this gene is glmU

Identifier: 15618658

GI number: 15618658

Start: 845003

End: 845629

Strand: Reverse

Name: glmU

Synonym: CPn0749

Alternate gene names: 15618658

Gene position: 845629-845003 (Counterclockwise)

Preceding gene: 15618659

Following gene: 15618657

Centisome position: 68.74

GC content: 41.79

Gene sequence:

>627_bases
ATGACTTATCTAGCCTCGTCTATATTTTCTCCTGAGGACTTTCTCTATCCTGAGATAATCTCCAAAGCTCACTATACCTG
GGATATTCTTGATTTAATGGATCAGATGCTGGAAAACCACGTGTTTTCTGGGATTCATGGTACTGTAGAGTCTGGTGTAA
CTTTAAAAAATATAGAAAAGATTGAGATTGCTGAAGATGCCTACGTAGAGTCTGGGGCTTACATTGTAGGACCATGCATT
CTTGGCTCACAAACAGAAGTTCGTCATGGGGCCTATCTGCGAGGCAATGTCATCACAGGCAGTCGCTGTGTTGTGGGTCA
CTGTACTGAAATCAAGAATAGCTATTTAGGTCATCATACGAAAGCCGCTCACTTTGCTTACCTCGGAGATTCTGTGTTAA
GTTCAGAAGTCAATCTAGGTGCTGGAGTACGTTGTGCTAATTTCCGTCTAGATGGAAGGAACATCTATGTTCGTTCTACC
TCAGATAAATCAAAAAAAATCGATACAGGGCGTCGTAAACTTGGTGCCTTTTTAGGAAAAGGGGTTGCTATAGGATGCAA
TGTTGTCATCAATCCAGGCCAACATATTCTCCCTCATACTAGAATTCGTCCTGGTCAAGTCATTTAA

Upstream 100 bases:

>100_bases
ATACAGCGCATCCAAACGAAGAGTAAAGTAAGTTCTTTATATCTTGTAAGTAAATCTTCAGAGTATGAAAATACTGAGGC
AAATAGCTTGAGTATGCTAT

Downstream 100 bases:

>100_bases
AAATAGGGGACTCTTGTGTTACATGCTTTAGATACGTATCGACCTTCTATAGAAAGTGCTATAGAAAAGGCTTTGGAAGG
ATTTGGTCCTATAGGTCACC

Product: UDP-GlcNAc pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTYLASSIFSPEDFLYPEIISKAHYTWDILDLMDQMLENHVFSGIHGTVESGVTLKNIEKIEIAEDAYVESGAYIVGPCI
LGSQTEVRHGAYLRGNVITGSRCVVGHCTEIKNSYLGHHTKAAHFAYLGDSVLSSEVNLGAGVRCANFRLDGRNIYVRST
SDKSKKIDTGRRKLGAFLGKGVAIGCNVVINPGQHILPHTRIRPGQVI

Sequences:

>Translated_208_residues
MTYLASSIFSPEDFLYPEIISKAHYTWDILDLMDQMLENHVFSGIHGTVESGVTLKNIEKIEIAEDAYVESGAYIVGPCI
LGSQTEVRHGAYLRGNVITGSRCVVGHCTEIKNSYLGHHTKAAHFAYLGDSVLSSEVNLGAGVRCANFRLDGRNIYVRST
SDKSKKIDTGRRKLGAFLGKGVAIGCNVVINPGQHILPHTRIRPGQVI
>Mature_207_residues
TYLASSIFSPEDFLYPEIISKAHYTWDILDLMDQMLENHVFSGIHGTVESGVTLKNIEKIEIAEDAYVESGAYIVGPCIL
GSQTEVRHGAYLRGNVITGSRCVVGHCTEIKNSYLGHHTKAAHFAYLGDSVLSSEVNLGAGVRCANFRLDGRNIYVRSTS
DKSKKIDTGRRKLGAFLGKGVAIGCNVVINPGQHILPHTRIRPGQVI

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 22745; Mature: 22614

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLASSIFSPEDFLYPEIISKAHYTWDILDLMDQMLENHVFSGIHGTVESGVTLKNIEK
CCCCCCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCHHHCCEEEECCEE
IEIAEDAYVESGAYIVGPCILGSQTEVRHGAYLRGNVITGSRCVVGHCTEIKNSYLGHHT
EEECCHHHHCCCCEEEEEEEECCCCCCCCCCEEECCEEECCEEEEEEHHHHHHHHCCCCC
KAAHFAYLGDSVLSSEVNLGAGVRCANFRLDGRNIYVRSTSDKSKKIDTGRRKLGAFLGK
CHHHHHHHCHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCC
GVAIGCNVVINPGQHILPHTRIRPGQVI
CEEEEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TYLASSIFSPEDFLYPEIISKAHYTWDILDLMDQMLENHVFSGIHGTVESGVTLKNIEK
CCCCCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCHHHCCEEEECCEE
IEIAEDAYVESGAYIVGPCILGSQTEVRHGAYLRGNVITGSRCVVGHCTEIKNSYLGHHT
EEECCHHHHCCCCEEEEEEEECCCCCCCCCCEEECCEEECCEEEEEEHHHHHHHHCCCCC
KAAHFAYLGDSVLSSEVNLGAGVRCANFRLDGRNIYVRSTSDKSKKIDTGRRKLGAFLGK
CHHHHHHHCHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCC
GVAIGCNVVINPGQHILPHTRIRPGQVI
CEEEEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA