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The map label for this gene is tolC [C]

Identifier: 15606342

GI number: 15606342

Start: 733053

End: 734306

Strand: Direct

Name: tolC [C]

Synonym: aq_1059

Alternate gene names: 15606342

Gene position: 733053-734306 (Clockwise)

Preceding gene: 15606341

Following gene: 15606343

Centisome position: 47.25

GC content: 39.71

Gene sequence:

>1254_bases
ATGTGGATAATACTGCTCATCCCGACACTTTTATTCTCCTTAGGGCTTCAGGAACTATGGAAAAGTGCCCTCAAGAAAAA
TCCCGAAATACTTGCCCAAAAACAGGACATTAGAGCCAAGGAGTATAAACTAAAGGCTACAAAGAACTTATACTTCCCTC
TCTTTGAAGCGCAGTACTCCCGCGCGTGGCTCAGTGAAAAACAAAAGCTTGAGGTATTTCCCTTTTCCTTTGATATGACG
AAAAAGAATTACGAGAACTACTCAATCTCCCTGAAGGAACTCCTCTACGACTTCGGAAGACGGGAGAAGTTAATAGACAT
TTCGGTAAAGGAACTAAAAGTGAGTCAATATTTTTACGAGGAAAAGAAACAAGAAATTTTGTACAAGGTTGCGGAAAATT
ACTTTAACGTTCTGAGCGTTAAGGGAAAGATAAGGATTTATGAGGAGGAATTAAAAGCGGTAAAATCCCAGTACCAACTC
GCAAAAGCTTACTACGAAAAAGGACTCGTTGCGATAACGGACCTTCTTCAGGCAAAGGTTCGCATACACGAAGTTAAGGA
AAAAATAAGAAAAGAAAAGGGAAATCTTGAAACGCTACTCGTGAACCTCTCAAACCTCACGGGAATAGAGAAAGAAAAAT
TAAGGAATATTCAAGAAATTGAAGGAATTCCTGAAATCAAAGATCTCAGTTATTACCTGAAAACGGCGTACGAAAGGAGG
GGAATTTTAAAGGCTCAAAAGGAAAAGGTAAAAATACTTGAGAACCTTGCAAGGATAAAAGCCCTTGAGTATGCGCCACA
AATTTTCGGAGGTTTAACTTACTACTACACCAACCAGAATCCAAACGTAGAACCAAAAGGTTTATTCAGTTATTACGTGG
GAGCTACCCTTTCATTCCAAACTCTAAAACCCTACTACGAACACCTTTCCCTGAAGAGGGAAAAAATAAAAGCTTTAAAG
GAGCTTGAAAGTCTGGAAAACTCAATAAAACTCCAAGTAAAGAGTGCTTATGAGGATGTTTTAACCGCTAAAGAAAACCT
GAAAACCGCAAAAGAGAGACTCAAGTTTGCAAAAAAGTACTACGAACTCGCTTTGGAACAGTACAAAAATCAATTAATAT
CCCAGACGGACCTCCTTATAGCGGAAGCCACCTTAACGAGTGCAAAGGAAGCCCTCCTGATAGCGAAAAACGAACTCTGG
AAGGCTTATTACAGACTCCTTTGGGCTTCTTCCCTTCTGGAGGTTGAAAGATGA

Upstream 100 bases:

>100_bases
AATTAATCCTGCACTACGTTATAAAGGAAGAAAGGGAACTCCCATTCCTAAAGGAAAAACTCAGGGAAGGGTTGAAGTTA
ATCTTCGAGGGAGTGAAAAA

Downstream 100 bases:

>100_bases
AAAAGTACATAGGCGTTTTTACGGTTGTGGCTTTAATTGTGGGCTTTGGGATTTACGCCTTTTTCTTCATAAAACACAGA
ATTGAGTATGCCATAACAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Type I Secretion Outer Membrane Protein; Outer Membrane Protein; Type I Secretion Outer Membrane Protein lc Family; Type I Secretion Outer Membrane Protein lC Family; RND Family Efflux Pump Outer Membrane Protein; Type I Secretion Outer Membrane Protein lC

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MWIILLIPTLLFSLGLQELWKSALKKNPEILAQKQDIRAKEYKLKATKNLYFPLFEAQYSRAWLSEKQKLEVFPFSFDMT
KKNYENYSISLKELLYDFGRREKLIDISVKELKVSQYFYEEKKQEILYKVAENYFNVLSVKGKIRIYEEELKAVKSQYQL
AKAYYEKGLVAITDLLQAKVRIHEVKEKIRKEKGNLETLLVNLSNLTGIEKEKLRNIQEIEGIPEIKDLSYYLKTAYERR
GILKAQKEKVKILENLARIKALEYAPQIFGGLTYYYTNQNPNVEPKGLFSYYVGATLSFQTLKPYYEHLSLKREKIKALK
ELESLENSIKLQVKSAYEDVLTAKENLKTAKERLKFAKKYYELALEQYKNQLISQTDLLIAEATLTSAKEALLIAKNELW
KAYYRLLWASSLLEVER

Sequences:

>Translated_417_residues
MWIILLIPTLLFSLGLQELWKSALKKNPEILAQKQDIRAKEYKLKATKNLYFPLFEAQYSRAWLSEKQKLEVFPFSFDMT
KKNYENYSISLKELLYDFGRREKLIDISVKELKVSQYFYEEKKQEILYKVAENYFNVLSVKGKIRIYEEELKAVKSQYQL
AKAYYEKGLVAITDLLQAKVRIHEVKEKIRKEKGNLETLLVNLSNLTGIEKEKLRNIQEIEGIPEIKDLSYYLKTAYERR
GILKAQKEKVKILENLARIKALEYAPQIFGGLTYYYTNQNPNVEPKGLFSYYVGATLSFQTLKPYYEHLSLKREKIKALK
ELESLENSIKLQVKSAYEDVLTAKENLKTAKERLKFAKKYYELALEQYKNQLISQTDLLIAEATLTSAKEALLIAKNELW
KAYYRLLWASSLLEVER
>Mature_417_residues
MWIILLIPTLLFSLGLQELWKSALKKNPEILAQKQDIRAKEYKLKATKNLYFPLFEAQYSRAWLSEKQKLEVFPFSFDMT
KKNYENYSISLKELLYDFGRREKLIDISVKELKVSQYFYEEKKQEILYKVAENYFNVLSVKGKIRIYEEELKAVKSQYQL
AKAYYEKGLVAITDLLQAKVRIHEVKEKIRKEKGNLETLLVNLSNLTGIEKEKLRNIQEIEGIPEIKDLSYYLKTAYERR
GILKAQKEKVKILENLARIKALEYAPQIFGGLTYYYTNQNPNVEPKGLFSYYVGATLSFQTLKPYYEHLSLKREKIKALK
ELESLENSIKLQVKSAYEDVLTAKENLKTAKERLKFAKKYYELALEQYKNQLISQTDLLIAEATLTSAKEALLIAKNELW
KAYYRLLWASSLLEVER

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49063; Mature: 49063

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWIILLIPTLLFSLGLQELWKSALKKNPEILAQKQDIRAKEYKLKATKNLYFPLFEAQYS
CEEHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
RAWLSEKQKLEVFPFSFDMTKKNYENYSISLKELLYDFGRREKLIDISVKELKVSQYFYE
HHHHCCCCCEEEECCEECCCCCCCCCCCEEHHHHHHHHCCCCEEEECHHHHHHHHHHHHH
EKKQEILYKVAENYFNVLSVKGKIRIYEEELKAVKSQYQLAKAYYEKGLVAITDLLQAKV
HHHHHHHHHHHHHHHHHHEECCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RIHEVKEKIRKEKGNLETLLVNLSNLTGIEKEKLRNIQEIEGIPEIKDLSYYLKTAYERR
HHHHHHHHHHHHCCCHHHEEEEHHHCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHH
GILKAQKEKVKILENLARIKALEYAPQIFGGLTYYYTNQNPNVEPKGLFSYYVGATLSFQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCEEEHH
TLKPYYEHLSLKREKIKALKELESLENSIKLQVKSAYEDVLTAKENLKTAKERLKFAKKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YELALEQYKNQLISQTDLLIAEATLTSAKEALLIAKNELWKAYYRLLWASSLLEVER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWIILLIPTLLFSLGLQELWKSALKKNPEILAQKQDIRAKEYKLKATKNLYFPLFEAQYS
CEEHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
RAWLSEKQKLEVFPFSFDMTKKNYENYSISLKELLYDFGRREKLIDISVKELKVSQYFYE
HHHHCCCCCEEEECCEECCCCCCCCCCCEEHHHHHHHHCCCCEEEECHHHHHHHHHHHHH
EKKQEILYKVAENYFNVLSVKGKIRIYEEELKAVKSQYQLAKAYYEKGLVAITDLLQAKV
HHHHHHHHHHHHHHHHHHEECCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RIHEVKEKIRKEKGNLETLLVNLSNLTGIEKEKLRNIQEIEGIPEIKDLSYYLKTAYERR
HHHHHHHHHHHHCCCHHHEEEEHHHCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHH
GILKAQKEKVKILENLARIKALEYAPQIFGGLTYYYTNQNPNVEPKGLFSYYVGATLSFQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCEEEHH
TLKPYYEHLSLKREKIKALKELESLENSIKLQVKSAYEDVLTAKENLKTAKERLKFAKKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YELALEQYKNQLISQTDLLIAEATLTSAKEALLIAKNELWKAYYRLLWASSLLEVER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA