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The map label for this gene is hypA

Identifier: 15606317

GI number: 15606317

Start: 707454

End: 707801

Strand: Direct

Name: hypA

Synonym: aq_1021

Alternate gene names: 15606317

Gene position: 707454-707801 (Clockwise)

Preceding gene: 15606316

Following gene: 15606318

Centisome position: 45.6

GC content: 43.68

Gene sequence:

>348_bases
ATGCACGAGTTTTCAATAGTTCAGAGTCTTCTCACACTGATAGAAGATTACGCAAGGGAGAACAACGCAAAAAGCGTTAC
GAAGGTCGTTGTAAGTATAGGCGTCCTTTCTGGCGTAGAACCGCACCTTCTTGAGATGGCTTTCAACACCTTTAAAGAAG
GAACGGTTGCTGAAAAGGCGGAGCTTATTATGGAAATAGAGAAGTTGAAGATAAAGTGTATGGACTGCGGGAAAGAGAGC
GAAAAGGAAGAACTGAATATGCTCTGCCCCGGGTGCGGTTCCCTGAACACTCAGATAATAAGCGGGCAGGACATGTTTTT
AAAGAGTTTGGAATTAGAAGTTGATTGA

Upstream 100 bases:

>100_bases
TGGTTAAAAAGGGAGAGCCGAAGGTAATACTTAGCACTCCTTACGGAGTAAAGAGGGTTATGGAACCGCCGGCGGGAGAA
CTCCTTCCGAGGATTTGCTA

Downstream 100 bases:

>100_bases
TGTTAATTTTACTGGACACAGGTATTCACGAAGTTGCATTCTTTACAAAATACGAAAATTACACGCTCTGCACCGTTGGG
AGGAGGGAAAACTCAAAGGA

Product: hydrogenase accessory protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MHEFSIVQSLLTLIEDYARENNAKSVTKVVVSIGVLSGVEPHLLEMAFNTFKEGTVAEKAELIMEIEKLKIKCMDCGKES
EKEELNMLCPGCGSLNTQIISGQDMFLKSLELEVD

Sequences:

>Translated_115_residues
MHEFSIVQSLLTLIEDYARENNAKSVTKVVVSIGVLSGVEPHLLEMAFNTFKEGTVAEKAELIMEIEKLKIKCMDCGKES
EKEELNMLCPGCGSLNTQIISGQDMFLKSLELEVD
>Mature_115_residues
MHEFSIVQSLLTLIEDYARENNAKSVTKVVVSIGVLSGVEPHLLEMAFNTFKEGTVAEKAELIMEIEKLKIKCMDCGKES
EKEELNMLCPGCGSLNTQIISGQDMFLKSLELEVD

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=31.858407079646, Blast_Score=70, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_AQUAE (O67133)

Other databases:

- EMBL:   AE000657
- PIR:   B70388
- RefSeq:   NP_213696.1
- GeneID:   1193767
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1021
- NMPDR:   fig|224324.1.peg.711
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- PhylomeDB:   O67133
- ProtClustDB:   CLSK2748398
- BioCyc:   AAEO224324:AQ_1021-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- InterPro:   IPR004039
- Gene3D:   G3DSA:2.20.28.10
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12783; Mature: 12783

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEFSIVQSLLTLIEDYARENNAKSVTKVVVSIGVLSGVEPHLLEMAFNTFKEGTVAEKA
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHH
ELIMEIEKLKIKCMDCGKESEKEELNMLCPGCGSLNTQIISGQDMFLKSLELEVD
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCEEECCHHHHHHHHHCCCC
>Mature Secondary Structure
MHEFSIVQSLLTLIEDYARENNAKSVTKVVVSIGVLSGVEPHLLEMAFNTFKEGTVAEKA
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHH
ELIMEIEKLKIKCMDCGKESEKEELNMLCPGCGSLNTQIISGQDMFLKSLELEVD
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCEEECCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320