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The map label for this gene is hypE [H]

Identifier: 15606316

GI number: 15606316

Start: 706456

End: 707454

Strand: Direct

Name: hypE [H]

Synonym: aq_1019

Alternate gene names: 15606316

Gene position: 706456-707454 (Clockwise)

Preceding gene: 15606315

Following gene: 15606317

Centisome position: 45.54

GC content: 48.15

Gene sequence:

>999_bases
ATGAAAAAAATTCTTCTCTCTCACGGAGGAGGCGGTGAAGAAACGCAGAAACTTATAAAGAACCTCTTTTTAAAGTACTT
TTCAAACGAAATTTTAAACAAACTTGAAGACGCCTCACTCCTTAATCTGAGCGGTAAGGTTGCCTTCACAACGGATGCCT
TCACGGTTTCACCGATATTTTTCAGGGGAGGGGATATCGGAAAACTGGCCGTTGCCGGGACTGTAAACGACCTTTCGGTT
ATGGGCGCAAGGCCTAAATATCTTTCCGTTTCCTTCGTAATAGAGGAAGGTCTCTCCTTTGAAGAACTTGAAGAGGTAGT
AAAGAGTATGGCACAAGAAGCGTCAAAGACGGGCGTTCAGATAGTAGCGGGGGACACGAAGGTAGTTCCCAAAGGGCAGG
CGGACAAGTTGTTCATTTCCGCGTCCGGAATAGGAGAAGTCGTTTACGAAGGGCTTTCCGCCCACAACTTGAGAGAGGGA
AACGTGATAATAGTTTCGGGAAGCGTGGGAGACCACGGAGCTTGTATCCTGGCACAGAGAGAAGGTATGGAGTTTGAAGT
TCCCGTGGAGAGCGATTGTAAGAGTTTGTGGAACATGATTGAAAAGGTTTTGAGTAGCGGTGCTGAAGTTCACGCCATCA
GGGACGCAACGAGAGGCGGACTTGCAGGTGTTCTGAACGAGTGGGCAGAGCAATCAAAGGTAACCATAGAAGTTGAAGAG
GAAAAGATTCCCGTAAAAGAAGCCGTGAGGGGACTTTGTGAACTCCTCGGATTTGAACCGACTCACCTCGCAAACGAGGG
AATGGCAGTATTTGCAGTGGCATCCCAAGACGCCCAAAAGGTTTTAGAAATCCTTCGCTCCACTCCCGAAGGCAAGGAAG
CCCAGATTATAGGAAAGGTGGTTAAAAAGGGAGAGCCGAAGGTAATACTTAGCACTCCTTACGGAGTAAAGAGGGTTATG
GAACCGCCGGCGGGAGAACTCCTTCCGAGGATTTGCTAA

Upstream 100 bases:

>100_bases
TATTTGAAAAGCTCGATTTACTTGTTCCTGATCACAGGATAATTCCCACAGTAAACCTTTTAGATTTGATTCAGAAGAAG
GCAAATGTAAAATCAAAATT

Downstream 100 bases:

>100_bases
TGCACGAGTTTTCAATAGTTCAGAGTCTTCTCACACTGATAGAAGATTACGCAAGGGAGAACAACGCAAAAAGCGTTACG
AAGGTCGTTGTAAGTATAGG

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKKILLSHGGGGEETQKLIKNLFLKYFSNEILNKLEDASLLNLSGKVAFTTDAFTVSPIFFRGGDIGKLAVAGTVNDLSV
MGARPKYLSVSFVIEEGLSFEELEEVVKSMAQEASKTGVQIVAGDTKVVPKGQADKLFISASGIGEVVYEGLSAHNLREG
NVIIVSGSVGDHGACILAQREGMEFEVPVESDCKSLWNMIEKVLSSGAEVHAIRDATRGGLAGVLNEWAEQSKVTIEVEE
EKIPVKEAVRGLCELLGFEPTHLANEGMAVFAVASQDAQKVLEILRSTPEGKEAQIIGKVVKKGEPKVILSTPYGVKRVM
EPPAGELLPRIC

Sequences:

>Translated_332_residues
MKKILLSHGGGGEETQKLIKNLFLKYFSNEILNKLEDASLLNLSGKVAFTTDAFTVSPIFFRGGDIGKLAVAGTVNDLSV
MGARPKYLSVSFVIEEGLSFEELEEVVKSMAQEASKTGVQIVAGDTKVVPKGQADKLFISASGIGEVVYEGLSAHNLREG
NVIIVSGSVGDHGACILAQREGMEFEVPVESDCKSLWNMIEKVLSSGAEVHAIRDATRGGLAGVLNEWAEQSKVTIEVEE
EKIPVKEAVRGLCELLGFEPTHLANEGMAVFAVASQDAQKVLEILRSTPEGKEAQIIGKVVKKGEPKVILSTPYGVKRVM
EPPAGELLPRIC
>Mature_332_residues
MKKILLSHGGGGEETQKLIKNLFLKYFSNEILNKLEDASLLNLSGKVAFTTDAFTVSPIFFRGGDIGKLAVAGTVNDLSV
MGARPKYLSVSFVIEEGLSFEELEEVVKSMAQEASKTGVQIVAGDTKVVPKGQADKLFISASGIGEVVYEGLSAHNLREG
NVIIVSGSVGDHGACILAQREGMEFEVPVESDCKSLWNMIEKVLSSGAEVHAIRDATRGGLAGVLNEWAEQSKVTIEVEE
EKIPVKEAVRGLCELLGFEPTHLANEGMAVFAVASQDAQKVLEILRSTPEGKEAQIIGKVVKKGEPKVILSTPYGVKRVM
EPPAGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=341, Percent_Identity=46.3343108504399, Blast_Score=290, Evalue=7e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35608; Mature: 35608

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLSHGGGGEETQKLIKNLFLKYFSNEILNKLEDASLLNLSGKVAFTTDAFTVSPIF
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCEEECEEE
FRGGDIGKLAVAGTVNDLSVMGARPKYLSVSFVIEEGLSFEELEEVVKSMAQEASKTGVQ
ECCCCCCEEEEECCCCHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEE
IVAGDTKVVPKGQADKLFISASGIGEVVYEGLSAHNLREGNVIIVSGSVGDHGACILAQR
EEECCEEECCCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEC
EGMEFEVPVESDCKSLWNMIEKVLSSGAEVHAIRDATRGGLAGVLNEWAEQSKVTIEVEE
CCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCHHHHHHHHHHCCEEEEEEEC
EKIPVKEAVRGLCELLGFEPTHLANEGMAVFAVASQDAQKVLEILRSTPEGKEAQIIGKV
CCCCHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHH
VKKGEPKVILSTPYGVKRVMEPPAGELLPRIC
HHCCCCCEEEECCCCHHHHCCCCHHHHCCCCC
>Mature Secondary Structure
MKKILLSHGGGGEETQKLIKNLFLKYFSNEILNKLEDASLLNLSGKVAFTTDAFTVSPIF
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCEEECEEE
FRGGDIGKLAVAGTVNDLSVMGARPKYLSVSFVIEEGLSFEELEEVVKSMAQEASKTGVQ
ECCCCCCEEEEECCCCHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEE
IVAGDTKVVPKGQADKLFISASGIGEVVYEGLSAHNLREGNVIIVSGSVGDHGACILAQR
EEECCEEECCCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEC
EGMEFEVPVESDCKSLWNMIEKVLSSGAEVHAIRDATRGGLAGVLNEWAEQSKVTIEVEE
CCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCHHHHHHHHHHCCEEEEEEEC
EKIPVKEAVRGLCELLGFEPTHLANEGMAVFAVASQDAQKVLEILRSTPEGKEAQIIGKV
CCCCHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHH
VKKGEPKVILSTPYGVKRVMEPPAGELLPRIC
HHCCCCCEEEECCCCHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]