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The map label for this gene is fabD [H]

Identifier: 15606225

GI number: 15606225

Start: 616148

End: 617128

Strand: Direct

Name: fabD [H]

Synonym: aq_892

Alternate gene names: 15606225

Gene position: 616148-617128 (Clockwise)

Preceding gene: 15606223

Following gene: 15606226

Centisome position: 39.72

GC content: 48.83

Gene sequence:

>981_bases
ATGGACGCCACCCTCATAATTGGTTTATTATCTAAAGACATGGGCAAGCTCGCTTACGTTTTTCCCGGACAAGGTTCCCA
ATACGTGGGTATGGGATACGAGTTTTACAAGCAGTTCCACGAGACCGCTGACGTGGTTCACGCGGTTGAACACTCCCTCA
GAATGTCTTTAGACGATATCGTTGACGTTATGTTCAAGGGTCCAGAAGAGAAACTGAACAAAACCGTATACACCCAACCT
GCACTCTTTGCGATTTCTCTCGGTATATACAAAGCCCTTGAGAGTATGGGATTTCCAAAGCCAGACTTTGTAGCGGGGCA
CTCCCTCGGAGAGTATACAGCCCTTGCTGTTGCGGGCGGGATAGACGTTCAGCTCGGGGCAAGACTCACCTATTACAGGG
GAAAGTACATGCAGGAGGCTGTTCCCGAAGGAAAGGGAGCTATGGTGGCGATTCTGAAACTCCCTCCTGAAAAGGTAGAA
GAAGCGTGTGAAAGGGCGAAGGACGTCGGGGTGGTTGAACCGGCAAACTACAACTCATCTACCCAAACCGTGATATCGGG
GGAAAAGCCTGCGGTTGAAAAGGCCGCCCAGATAGCAAAGGAAATGGGTGGAAGGGCAATCCCGTTGAAGGTTTCAGTTC
CCTCCCACTGCTCACTGATGAAACCCGCGGCGGACGCCTTTAGGCTTAAACTCGCTCAAGCTCCGATTCAAAATATTAAA
ATCCCTCTGGTTCAGAACTACACCGCAAAGGCTCACACCATGGCACACGAGATAAGGAACAACCTTTACCATCAGATATT
TTCCCCGGTAAAGTGGTATCAGAGTGTTATATGGATGCACGAACAGGGAGTTGATACCTTCGTAGAAATAGGTCCAAAGA
ACGTTCTCTCAAAACTCATACAGCAAACGCTCCCGAACGTGAGGGTGTTTAACGTTGAAAAACCAGAAGATGCGGAAAGC
GTTTTAAAGGCGATAACATGA

Upstream 100 bases:

>100_bases
TGTCCCGAGGGAGGTAATCCTTCCCCTCTCAAGGATTATGGAGAGTTTTCCGTCTTTGATTTGGGCTATCGTTAGTCTCA
CGGAGTAGGAGCCTATGTCT

Downstream 100 bases:

>100_bases
GGGCTCATCCCGAGTGCATTCCCTGTCTTATAAATCAGGGCCTGAACGCCGTAAAGAAGTTAAACCTTCCAAAAGAAAAG
GAAATGGAAATAGCAACAAG

Product: malonyl-CoA:Acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MDATLIIGLLSKDMGKLAYVFPGQGSQYVGMGYEFYKQFHETADVVHAVEHSLRMSLDDIVDVMFKGPEEKLNKTVYTQP
ALFAISLGIYKALESMGFPKPDFVAGHSLGEYTALAVAGGIDVQLGARLTYYRGKYMQEAVPEGKGAMVAILKLPPEKVE
EACERAKDVGVVEPANYNSSTQTVISGEKPAVEKAAQIAKEMGGRAIPLKVSVPSHCSLMKPAADAFRLKLAQAPIQNIK
IPLVQNYTAKAHTMAHEIRNNLYHQIFSPVKWYQSVIWMHEQGVDTFVEIGPKNVLSKLIQQTLPNVRVFNVEKPEDAES
VLKAIT

Sequences:

>Translated_326_residues
MDATLIIGLLSKDMGKLAYVFPGQGSQYVGMGYEFYKQFHETADVVHAVEHSLRMSLDDIVDVMFKGPEEKLNKTVYTQP
ALFAISLGIYKALESMGFPKPDFVAGHSLGEYTALAVAGGIDVQLGARLTYYRGKYMQEAVPEGKGAMVAILKLPPEKVE
EACERAKDVGVVEPANYNSSTQTVISGEKPAVEKAAQIAKEMGGRAIPLKVSVPSHCSLMKPAADAFRLKLAQAPIQNIK
IPLVQNYTAKAHTMAHEIRNNLYHQIFSPVKWYQSVIWMHEQGVDTFVEIGPKNVLSKLIQQTLPNVRVFNVEKPEDAES
VLKAIT
>Mature_326_residues
MDATLIIGLLSKDMGKLAYVFPGQGSQYVGMGYEFYKQFHETADVVHAVEHSLRMSLDDIVDVMFKGPEEKLNKTVYTQP
ALFAISLGIYKALESMGFPKPDFVAGHSLGEYTALAVAGGIDVQLGARLTYYRGKYMQEAVPEGKGAMVAILKLPPEKVE
EACERAKDVGVVEPANYNSSTQTVISGEKPAVEKAAQIAKEMGGRAIPLKVSVPSHCSLMKPAADAFRLKLAQAPIQNIK
IPLVQNYTAKAHTMAHEIRNNLYHQIFSPVKWYQSVIWMHEQGVDTFVEIGPKNVLSKLIQQTLPNVRVFNVEKPEDAES
VLKAIT

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=311, Percent_Identity=30.8681672025724, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI41872631, Length=325, Percent_Identity=24.6153846153846, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1787334, Length=311, Percent_Identity=41.4790996784566, Blast_Score=229, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17550940, Length=331, Percent_Identity=26.8882175226586, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71984332, Length=311, Percent_Identity=26.6881028938907, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI212642053, Length=321, Percent_Identity=26.4797507788162, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=34.3234323432343, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 35896; Mature: 35896

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATLIIGLLSKDMGKLAYVFPGQGSQYVGMGYEFYKQFHETADVVHAVEHSLRMSLDDI
CCCEEEEEHHHCCCCCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VDVMFKGPEEKLNKTVYTQPALFAISLGIYKALESMGFPKPDFVAGHSLGEYTALAVAGG
HHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEECC
IDVQLGARLTYYRGKYMQEAVPEGKGAMVAILKLPPEKVEEACERAKDVGVVEPANYNSS
CEEEECCEEEHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCC
TQTVISGEKPAVEKAAQIAKEMGGRAIPLKVSVPSHCSLMKPAADAFRLKLAQAPIQNIK
CCEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCHHHHHHHHHHHCCHHHCC
IPLVQNYTAKAHTMAHEIRNNLYHQIFSPVKWYQSVIWMHEQGVDTFVEIGPKNVLSKLI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHH
QQTLPNVRVFNVEKPEDAESVLKAIT
HHHCCCCEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MDATLIIGLLSKDMGKLAYVFPGQGSQYVGMGYEFYKQFHETADVVHAVEHSLRMSLDDI
CCCEEEEEHHHCCCCCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VDVMFKGPEEKLNKTVYTQPALFAISLGIYKALESMGFPKPDFVAGHSLGEYTALAVAGG
HHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEECC
IDVQLGARLTYYRGKYMQEAVPEGKGAMVAILKLPPEKVEEACERAKDVGVVEPANYNSS
CEEEECCEEEHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCC
TQTVISGEKPAVEKAAQIAKEMGGRAIPLKVSVPSHCSLMKPAADAFRLKLAQAPIQNIK
CCEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCHHHHHHHHHHHCCHHHCC
IPLVQNYTAKAHTMAHEIRNNLYHQIFSPVKWYQSVIWMHEQGVDTFVEIGPKNVLSKLI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHH
QQTLPNVRVFNVEKPEDAESVLKAIT
HHHCCCCEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]