Click here to switch to the map view.

The map label for this gene is thiO/thiG [H]

Identifier: 15606107

GI number: 15606107

Start: 483583

End: 484644

Strand: Direct

Name: thiO/thiG [H]

Synonym: aq_707

Alternate gene names: 15606107

Gene position: 483583-484644 (Clockwise)

Preceding gene: 15606106

Following gene: 15606108

Centisome position: 31.17

GC content: 46.99

Gene sequence:

>1062_bases
ATGGAAATCCTTGTAATAGGCGGTGGGGTAATAGGACTATCCATCGGGGTAGAACTGCTCCTTGCGGGACACGATGTAAG
ACTCCTCGTCAGAGATAAAAGGGAAGGTGCTTCCTGGGTGGCGGGCGGTATGCTCGCCCCCTTTTCGGAAGGTCTGAGGG
GAGATTTTTTAAGGTTTTCCGTGGAAAGTCTAAGGCTCTGGCACGACTACCTTGAAAGACTGAAGGAAATTTCGGGGAGA
AAAGTTTTCTTCTCTCAGGGAATACTCAGAGTAGCCTTTGACGAGAAAGAAGAAAAGAAATTGAGAGAGGACGTTAAGTT
TTACTCTCAGGAAGTGTGTCAGAACCTTATCTCTTACGACGCTGAAGAACTCCTAAAAGAGTTTCCCTACCTTTCGAGTG
AAGTCAGGTACGGAGTTATATACGGAGATGAGGGAAATGTAGACACGGAAGAGCTTATGGAAGCCCTTTACGTTGCCTTT
GAAAAACTCGGTGGAGAAATAATAAACGAGGACGCGGTAAAGATTCTGAGGAACGGAGAGAGAATAGAAAAAGTCTTCGG
CTTTTTTGAGGAGTTTACTGCGGATTACTACGTGTTTGCAACGGGTGCTTGGCTAAAAGAACACTTCGGCTTTCCCGTAT
TCCCGGTAAAGGGGCAGATACTCAGGGTTGAAGCACCCCTCAAAGACTACGTTGTTTACTCCTCAAGGGCATACATAATC
CCGAGGGAAAAGGACCTTTTAATAGGCGCGACAACCGAAAACGCTGGCTTTGACACGAAAACAACTTTAGAAGGTGTTAA
AAAACTTTCCGAAGGGGCGATATCGAGCGTCCCTCAGCTCAAGGAAGCTCAACTTCTTGAGGTAAGAGTCGGCTTTAGAC
CCGGAACGCCCGATGAACTTCCCGTTTTTTACTTTGGAGAAAACTTTTCAGTTTACGGAGGGCATTACAGGAACGGCATA
CTCCTCGCTCCCGCAACCGCTGAGGTAGCCCTGAAGTTAATAGACCAGGGGGAGGTTTCGGAATACTTCAAGACTTTCTC
CCCTTACAGGTTCAAGGAGTAA

Upstream 100 bases:

>100_bases
GGACGGGATAGTTGTTATTAACCTCTCAGGAAGGGGAGACAAGGATATGGCACACGTTATGAAACACCTTTCACTCGAAG
GCTAATATCATTAAAGTATT

Downstream 100 bases:

>100_bases
ATAATGAGAGTTTACGTGGGCGTTGATACAGGCGGGACCTTTACAGACTTCGTTTACTGGGACGGAAAGGAGTGGCGTGT
CCTCAAAATCCCATCTACTC

Product: hypothetical protein

Products: NA

Alternate protein names: Probable FAD-dependent glycine oxidase; Thiazole synthase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEILVIGGGVIGLSIGVELLLAGHDVRLLVRDKREGASWVAGGMLAPFSEGLRGDFLRFSVESLRLWHDYLERLKEISGR
KVFFSQGILRVAFDEKEEKKLREDVKFYSQEVCQNLISYDAEELLKEFPYLSSEVRYGVIYGDEGNVDTEELMEALYVAF
EKLGGEIINEDAVKILRNGERIEKVFGFFEEFTADYYVFATGAWLKEHFGFPVFPVKGQILRVEAPLKDYVVYSSRAYII
PREKDLLIGATTENAGFDTKTTLEGVKKLSEGAISSVPQLKEAQLLEVRVGFRPGTPDELPVFYFGENFSVYGGHYRNGI
LLAPATAEVALKLIDQGEVSEYFKTFSPYRFKE

Sequences:

>Translated_353_residues
MEILVIGGGVIGLSIGVELLLAGHDVRLLVRDKREGASWVAGGMLAPFSEGLRGDFLRFSVESLRLWHDYLERLKEISGR
KVFFSQGILRVAFDEKEEKKLREDVKFYSQEVCQNLISYDAEELLKEFPYLSSEVRYGVIYGDEGNVDTEELMEALYVAF
EKLGGEIINEDAVKILRNGERIEKVFGFFEEFTADYYVFATGAWLKEHFGFPVFPVKGQILRVEAPLKDYVVYSSRAYII
PREKDLLIGATTENAGFDTKTTLEGVKKLSEGAISSVPQLKEAQLLEVRVGFRPGTPDELPVFYFGENFSVYGGHYRNGI
LLAPATAEVALKLIDQGEVSEYFKTFSPYRFKE
>Mature_353_residues
MEILVIGGGVIGLSIGVELLLAGHDVRLLVRDKREGASWVAGGMLAPFSEGLRGDFLRFSVESLRLWHDYLERLKEISGR
KVFFSQGILRVAFDEKEEKKLREDVKFYSQEVCQNLISYDAEELLKEFPYLSSEVRYGVIYGDEGNVDTEELMEALYVAF
EKLGGEIINEDAVKILRNGERIEKVFGFFEEFTADYYVFATGAWLKEHFGFPVFPVKGQILRVEAPLKDYVVYSSRAYII
PREKDLLIGATTENAGFDTKTTLEGVKKLSEGAISSVPQLKEAQLLEVRVGFRPGTPDELPVFYFGENFSVYGGHYRNGI
LLAPATAEVALKLIDQGEVSEYFKTFSPYRFKE

Specific function: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the thiG family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006076
- InterPro:   IPR012727
- InterPro:   IPR008867 [H]

Pfam domain/function: PF01266 DAO; PF05690 ThiG [H]

EC number: NA

Molecular weight: Translated: 39922; Mature: 39922

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILVIGGGVIGLSIGVELLLAGHDVRLLVRDKREGASWVAGGMLAPFSEGLRGDFLRFS
CEEEEECCCCEEHHHCEEEEEECCCEEEEEEECCCCCCHHHCCCCCHHHCCCCCHHHHHH
VESLRLWHDYLERLKEISGRKVFFSQGILRVAFDEKEEKKLREDVKFYSQEVCQNLISYD
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
AEELLKEFPYLSSEVRYGVIYGDEGNVDTEELMEALYVAFEKLGGEIINEDAVKILRNGE
HHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHCHHHHHHHHCCH
RIEKVFGFFEEFTADYYVFATGAWLKEHFGFPVFPVKGQILRVEAPLKDYVVYSSRAYII
HHHHHHHHHHHHCCCEEEEEECHHHHHHCCCCEEECCCEEEEEECCHHHHEEECCCEEEE
PREKDLLIGATTENAGFDTKTTLEGVKKLSEGAISSVPQLKEAQLLEVRVGFRPGTPDEL
ECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCC
PVFYFGENFSVYGGHYRNGILLAPATAEVALKLIDQGEVSEYFKTFSPYRFKE
EEEEECCCEEEECCEECCCEEEECCHHHHHHHHHCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEILVIGGGVIGLSIGVELLLAGHDVRLLVRDKREGASWVAGGMLAPFSEGLRGDFLRFS
CEEEEECCCCEEHHHCEEEEEECCCEEEEEEECCCCCCHHHCCCCCHHHCCCCCHHHHHH
VESLRLWHDYLERLKEISGRKVFFSQGILRVAFDEKEEKKLREDVKFYSQEVCQNLISYD
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
AEELLKEFPYLSSEVRYGVIYGDEGNVDTEELMEALYVAFEKLGGEIINEDAVKILRNGE
HHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHCHHHHHHHHCCH
RIEKVFGFFEEFTADYYVFATGAWLKEHFGFPVFPVKGQILRVEAPLKDYVVYSSRAYII
HHHHHHHHHHHHCCCEEEEEECHHHHHHCCCCEEECCCEEEEEECCHHHHEEECCCEEEE
PREKDLLIGATTENAGFDTKTTLEGVKKLSEGAISSVPQLKEAQLLEVRVGFRPGTPDEL
ECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCC
PVFYFGENFSVYGGHYRNGILLAPATAEVALKLIDQGEVSEYFKTFSPYRFKE
EEEEECCCEEEECCEECCCEEEECCHHHHHHHHHCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA