Click here to switch to the map view.

The map label for this gene is accD [H]

Identifier: 15605937

GI number: 15605937

Start: 303136

End: 303966

Strand: Direct

Name: accD [H]

Synonym: aq_445

Alternate gene names: 15605937

Gene position: 303136-303966 (Clockwise)

Preceding gene: 15605936

Following gene: 15605938

Centisome position: 19.54

GC content: 46.81

Gene sequence:

>831_bases
ATGCGTTTCTTAGATAGATTCTTCAAAAAGAAGAAGAAAGAGGAGGCTCTATGGACAAAGTGTCCGAACTGTAAAAGCCT
CCTCTACGTTCCCGACCTGGAGAGCAACCTGAAAGTTTGCCCCAATTGCGACTACCACTTCACCCTTTCCGCCCTTGAGC
GTATAAAGTACACCCTCGATGAGGAAAATCCCGAACTCCTATTTGAAGAAATACTACCCGCGGATCCTCTGAACTTCAAA
GACACGAAAAGCTATAAGGACAGGATAAAGAAAGCACAGGAGGAGACGGGACTGAGTGAAGCAATAGTCATAACGGAGGG
GCACATAAAGGGGAAAAGGGCGATACTCGCGGTTATGGACTTTAACTTCATAGGCGGAAGTATGGGCTCTGTGGTCGGGG
AGCGGTTCTTCAGAGCCTGTGAGAGGGCTGTAGAGACTAAAACTCCGTTGATATCCTTTGCAGCGTCGGGCGGGGCGAGA
ATGCAGGAAGGAATACTCTCTTTAATGCAAATGGCAAAGACTACCTTCGGAGTGGGTTTACTAAAGGAGGCAAACATACC
TTACATAAGCGTTTTGACCAATCCCACAATGGGTGGCGTTTCTGCAAGTTTTGCCTTTCTGGGCGATTTAATATTGGCAG
AACCAAAGGCGTTAATAGGGTTCGCGGGACCGAGGGTGATAGAACAAACTATAAAGCAAAAGCTTCCCGAGGGATTTCAA
ACTGCGGAATTCCTCCTTGAAAAGGGACAGATAGACATGGTAGTCCACAGAAAAGAATTGAAGGACAAACTCGCCTACTT
TTTAGAGGTTATGTACTACGCAAAGCGGTGA

Upstream 100 bases:

>100_bases
AGGGTGTGGCGGAATTCGTGGGAGCACAACCGGAGAACGCCTTCCTCGGTTATATAATGGCGGTTTACGAAAAACTCAAG
AGGGAAAAAGAACAGGCTTA

Downstream 100 bases:

>100_bases
AGGAGTACCTAGATATCTTCTTTCTTGAAAAATATCCCTTCCCTTTATACGAGGCTTTTTTAAGGATAGTATTTGCGGCA
CTGCTGGGGGCACTTATCGG

Product: acetyl-CoA carboxyltransferase beta subunit

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRFLDRFFKKKKKEEALWTKCPNCKSLLYVPDLESNLKVCPNCDYHFTLSALERIKYTLDEENPELLFEEILPADPLNFK
DTKSYKDRIKKAQEETGLSEAIVITEGHIKGKRAILAVMDFNFIGGSMGSVVGERFFRACERAVETKTPLISFAASGGAR
MQEGILSLMQMAKTTFGVGLLKEANIPYISVLTNPTMGGVSASFAFLGDLILAEPKALIGFAGPRVIEQTIKQKLPEGFQ
TAEFLLEKGQIDMVVHRKELKDKLAYFLEVMYYAKR

Sequences:

>Translated_276_residues
MRFLDRFFKKKKKEEALWTKCPNCKSLLYVPDLESNLKVCPNCDYHFTLSALERIKYTLDEENPELLFEEILPADPLNFK
DTKSYKDRIKKAQEETGLSEAIVITEGHIKGKRAILAVMDFNFIGGSMGSVVGERFFRACERAVETKTPLISFAASGGAR
MQEGILSLMQMAKTTFGVGLLKEANIPYISVLTNPTMGGVSASFAFLGDLILAEPKALIGFAGPRVIEQTIKQKLPEGFQ
TAEFLLEKGQIDMVVHRKELKDKLAYFLEVMYYAKR
>Mature_276_residues
MRFLDRFFKKKKKEEALWTKCPNCKSLLYVPDLESNLKVCPNCDYHFTLSALERIKYTLDEENPELLFEEILPADPLNFK
DTKSYKDRIKKAQEETGLSEAIVITEGHIKGKRAILAVMDFNFIGGSMGSVVGERFFRACERAVETKTPLISFAASGGAR
MQEGILSLMQMAKTTFGVGLLKEANIPYISVLTNPTMGGVSASFAFLGDLILAEPKALIGFAGPRVIEQTIKQKLPEGFQ
TAEFLLEKGQIDMVVHRKELKDKLAYFLEVMYYAKR

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=260, Percent_Identity=56.9230769230769, Blast_Score=309, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI25147359, Length=145, Percent_Identity=26.2068965517241, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147362, Length=145, Percent_Identity=26.2068965517241, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 31086; Mature: 31086

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLDRFFKKKKKEEALWTKCPNCKSLLYVPDLESNLKVCPNCDYHFTLSALERIKYTLD
CCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
EENPELLFEEILPADPLNFKDTKSYKDRIKKAQEETGLSEAIVITEGHIKGKRAILAVMD
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEE
FNFIGGSMGSVVGERFFRACERAVETKTPLISFAASGGARMQEGILSLMQMAKTTFGVGL
CHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LKEANIPYISVLTNPTMGGVSASFAFLGDLILAEPKALIGFAGPRVIEQTIKQKLPEGFQ
HCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCHH
TAEFLLEKGQIDMVVHRKELKDKLAYFLEVMYYAKR
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFLDRFFKKKKKEEALWTKCPNCKSLLYVPDLESNLKVCPNCDYHFTLSALERIKYTLD
CCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
EENPELLFEEILPADPLNFKDTKSYKDRIKKAQEETGLSEAIVITEGHIKGKRAILAVMD
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEE
FNFIGGSMGSVVGERFFRACERAVETKTPLISFAASGGARMQEGILSLMQMAKTTFGVGL
CHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LKEANIPYISVLTNPTMGGVSASFAFLGDLILAEPKALIGFAGPRVIEQTIKQKLPEGFQ
HCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCHH
TAEFLLEKGQIDMVVHRKELKDKLAYFLEVMYYAKR
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA