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The map label for this gene is comM [H]

Identifier: 15605825

GI number: 15605825

Start: 188378

End: 189856

Strand: Direct

Name: comM [H]

Synonym: aq_291

Alternate gene names: 15605825

Gene position: 188378-189856 (Clockwise)

Preceding gene: 15605819

Following gene: 15605826

Centisome position: 12.14

GC content: 45.98

Gene sequence:

>1479_bases
ATGTTTTCTAAAGTCCTGAGCGGAGGGCTGTGGGGAGTAGAAGCCTTTCCGGTAGAAGTTCAGGTAGATATCTCTCAGGG
GCTTCCTTCCTTCAACGTAGTGGGGCTTCCAGACAGTTCCGTAAAAGAGGCAAGGGAGAGGGTAAGGAGTGCTGTAAAGA
ACTCCGGATTTTCCTTTCCCTTGAAACGGATAACCGTGAACCTCTCCCCTTCCGACAGGAAGAAACAGGGGACCTTTTAC
GACCTTCCCATAGCCCTCGGTATTTTGCAGTCTTCCGGAGAAATTCCGGAACACGATTTCGTAGTTCTGGGGGAACTTTC
CCTGGACGGGAGCTTAAATAAACTCAGCGGATTACTTGCGGTCCTGATTTCTTTAAAGGAGAAAGGCTTTAAGAAGTTCA
TAATCCCGAAACAGAACGCAGGAGAGGCTTCTCTTATAAAAGGTGTAGAGGTTTACACCTTTGAAAACTTGAAAGAAGTA
GTTGAGTTTTTAAGGGGAAATCTGAAAAGAGAACCTATTTCCCACAGGAAACATCAAGTGATAGAAATTTTTGAAGGAGA
CTTAAAAGATGTAAAGGGACAGGAACTCGCAAAAAGAGCCCTTGAGATATGTGCTGCGGGCTTTCATCACCTTCTCTTTG
TAGGAAGTGCGGGAGCGGGAAAGTCCATGCTTGCCACAAGGATTAAGAGCATAGCCCCGCCGATGGAAGAGGAAGAAATT
CTTGAAGTATCAAAAATCTACAGCGTTGCGGGGATGCTTGAAGAGAGCCTGATAACCGAAAGGCCCTTTCAAGCTCCTCA
CCACACGAGCTCAGAAGTCTCCCTGATAGGTGGAGGAAATCCTCCGAAACCCGGACTCATATCCTTGGCCCACAGGGGTT
ACTTATTTCTGGATGAAATGGCTGAATTTCCGAGGCGATTTATAGAGTCCTTAAGGCAGCCTATGGAAAACGGTAAGGTT
CAGGTGAGCAGGGCCGGAAGTAACGTAGTTTTTCCTGCGGAGTTTACCCTGCTTGGGGCCATGAACCCCTGCCCCTGCGG
AAATTACAAAAACCCTTTTAAGGTTTGCACGTGTTCGGAAAGGGAAATAAAAAATTACAACAAAAAGATATCAGAACCAA
TAAAAGACAGAATAGACCTCAAAGTTTGGGTGTACCCCCTGAAGGAGGAGGAACTCGTAAACCTCCCTGAAGGGGAAAGT
TCCGAGAAAGTAAGGGAAAGGGTGATAAGGGCCTTCCGGATACAAAAGGAGAGGGGAAAGTTTAACTCGAGACTCTCCAA
CGAAGAGGTAAAGAAGTACTGTCTGGACATGCTGTCAAGGGAAGCAAAAGAACTCTTAAAAGAAGCCGTTAAAAACTTAA
ACCTCTCGGCACGTTCCTACTTTAAACTCCTTAAAGTGGCAAGGACTATTGCGGACCTGGAGGAAAGTGAAAGGATAGAG
GATTATCACATTTCCGAGTGTTTGCAGTTTAGGGATTAA

Upstream 100 bases:

>100_bases
TAAAACCCATGAGGTGTGGGTCTGGATAACTTCTGCACCCAGTTCTTTTGCGAGTTCAAGTACTTTGCTCACAAGTGTAA
TTTTAACTTAGAATGTTTTT

Downstream 100 bases:

>100_bases
TATACTAACCATGAACAAACTCACTCTCTTGCTTAAGTTTTTGATACAAGCCTTCATGTGGTTTGCCATAGCTTCGGAAT
TCGTCTCCTTACTTTACGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MFSKVLSGGLWGVEAFPVEVQVDISQGLPSFNVVGLPDSSVKEARERVRSAVKNSGFSFPLKRITVNLSPSDRKKQGTFY
DLPIALGILQSSGEIPEHDFVVLGELSLDGSLNKLSGLLAVLISLKEKGFKKFIIPKQNAGEASLIKGVEVYTFENLKEV
VEFLRGNLKREPISHRKHQVIEIFEGDLKDVKGQELAKRALEICAAGFHHLLFVGSAGAGKSMLATRIKSIAPPMEEEEI
LEVSKIYSVAGMLEESLITERPFQAPHHTSSEVSLIGGGNPPKPGLISLAHRGYLFLDEMAEFPRRFIESLRQPMENGKV
QVSRAGSNVVFPAEFTLLGAMNPCPCGNYKNPFKVCTCSEREIKNYNKKISEPIKDRIDLKVWVYPLKEEELVNLPEGES
SEKVRERVIRAFRIQKERGKFNSRLSNEEVKKYCLDMLSREAKELLKEAVKNLNLSARSYFKLLKVARTIADLEESERIE
DYHISECLQFRD

Sequences:

>Translated_492_residues
MFSKVLSGGLWGVEAFPVEVQVDISQGLPSFNVVGLPDSSVKEARERVRSAVKNSGFSFPLKRITVNLSPSDRKKQGTFY
DLPIALGILQSSGEIPEHDFVVLGELSLDGSLNKLSGLLAVLISLKEKGFKKFIIPKQNAGEASLIKGVEVYTFENLKEV
VEFLRGNLKREPISHRKHQVIEIFEGDLKDVKGQELAKRALEICAAGFHHLLFVGSAGAGKSMLATRIKSIAPPMEEEEI
LEVSKIYSVAGMLEESLITERPFQAPHHTSSEVSLIGGGNPPKPGLISLAHRGYLFLDEMAEFPRRFIESLRQPMENGKV
QVSRAGSNVVFPAEFTLLGAMNPCPCGNYKNPFKVCTCSEREIKNYNKKISEPIKDRIDLKVWVYPLKEEELVNLPEGES
SEKVRERVIRAFRIQKERGKFNSRLSNEEVKKYCLDMLSREAKELLKEAVKNLNLSARSYFKLLKVARTIADLEESERIE
DYHISECLQFRD
>Mature_492_residues
MFSKVLSGGLWGVEAFPVEVQVDISQGLPSFNVVGLPDSSVKEARERVRSAVKNSGFSFPLKRITVNLSPSDRKKQGTFY
DLPIALGILQSSGEIPEHDFVVLGELSLDGSLNKLSGLLAVLISLKEKGFKKFIIPKQNAGEASLIKGVEVYTFENLKEV
VEFLRGNLKREPISHRKHQVIEIFEGDLKDVKGQELAKRALEICAAGFHHLLFVGSAGAGKSMLATRIKSIAPPMEEEEI
LEVSKIYSVAGMLEESLITERPFQAPHHTSSEVSLIGGGNPPKPGLISLAHRGYLFLDEMAEFPRRFIESLRQPMENGKV
QVSRAGSNVVFPAEFTLLGAMNPCPCGNYKNPFKVCTCSEREIKNYNKKISEPIKDRIDLKVWVYPLKEEELVNLPEGES
SEKVRERVIRAFRIQKERGKFNSRLSNEEVKKYCLDMLSREAKELLKEAVKNLNLSARSYFKLLKVARTIADLEESERIE
DYHISECLQFRD

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=489, Percent_Identity=40.8997955010225, Blast_Score=355, Evalue=5e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 55195; Mature: 55195

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSKVLSGGLWGVEAFPVEVQVDISQGLPSFNVVGLPDSSVKEARERVRSAVKNSGFSFP
CCHHHHCCCCCCCEEEEEEEEEEHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCE
LKRITVNLSPSDRKKQGTFYDLPIALGILQSSGEIPEHDFVVLGELSLDGSLNKLSGLLA
EEEEEEECCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHH
VLISLKEKGFKKFIIPKQNAGEASLIKGVEVYTFENLKEVVEFLRGNLKREPISHRKHQV
HHHHHHHCCCCEEECCCCCCCCHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCHHHHHHHH
IEIFEGDLKDVKGQELAKRALEICAAGFHHLLFVGSAGAGKSMLATRIKSIAPPMEEEEI
HHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCHHHH
LEVSKIYSVAGMLEESLITERPFQAPHHTSSEVSLIGGGNPPKPGLISLAHRGYLFLDEM
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCEEEHHHH
AEFPRRFIESLRQPMENGKVQVSRAGSNVVFPAEFTLLGAMNPCPCGNYKNPFKVCTCSE
HHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEECCCCCCCCCCCCCCEEEECCH
REIKNYNKKISEPIKDRIDLKVWVYPLKEEELVNLPEGESSEKVRERVIRAFRIQKERGK
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FNSRLSNEEVKKYCLDMLSREAKELLKEAVKNLNLSARSYFKLLKVARTIADLEESERIE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DYHISECLQFRD
HHHHHHHHHCCC
>Mature Secondary Structure
MFSKVLSGGLWGVEAFPVEVQVDISQGLPSFNVVGLPDSSVKEARERVRSAVKNSGFSFP
CCHHHHCCCCCCCEEEEEEEEEEHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCE
LKRITVNLSPSDRKKQGTFYDLPIALGILQSSGEIPEHDFVVLGELSLDGSLNKLSGLLA
EEEEEEECCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHH
VLISLKEKGFKKFIIPKQNAGEASLIKGVEVYTFENLKEVVEFLRGNLKREPISHRKHQV
HHHHHHHCCCCEEECCCCCCCCHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCHHHHHHHH
IEIFEGDLKDVKGQELAKRALEICAAGFHHLLFVGSAGAGKSMLATRIKSIAPPMEEEEI
HHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCHHHH
LEVSKIYSVAGMLEESLITERPFQAPHHTSSEVSLIGGGNPPKPGLISLAHRGYLFLDEM
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCEEEHHHH
AEFPRRFIESLRQPMENGKVQVSRAGSNVVFPAEFTLLGAMNPCPCGNYKNPFKVCTCSE
HHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEECCCCCCCCCCCCCCEEEECCH
REIKNYNKKISEPIKDRIDLKVWVYPLKEEELVNLPEGESSEKVRERVIRAFRIQKERGK
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FNSRLSNEEVKKYCLDMLSREAKELLKEAVKNLNLSARSYFKLLKVARTIADLEESERIE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DYHISECLQFRD
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]