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The map label for this gene is ntrC3 [H]

Identifier: 15605779

GI number: 15605779

Start: 141804

End: 143150

Strand: Direct

Name: ntrC3 [H]

Synonym: aq_230

Alternate gene names: 15605779

Gene position: 141804-143150 (Clockwise)

Preceding gene: 15605773

Following gene: 15605781

Centisome position: 9.14

GC content: 42.09

Gene sequence:

>1347_bases
ATGATTCTTTTGGTTGAAGATGACGACAACTTAAGGGAACTCCTTAAGAAAAAACTCGAAGAACACTTCGTGGTAGAAAC
TGCAAAAGACGGAAAGACGGCAAGGGAGAAGTTAAGTAAAAATAACTACGACGTTGTTCTCCTCGATATAAGACTTCCCG
ACGTAGACGGAACAGAACTTTTGAAAGAGTTTTCAACGAGCGGGGTTAAGTTCATAGTGATTACCGGCTACGGAGACGTA
AAAACGGCCGTCCAATGTGTAAAACTGGGAGCCTACGACTTTATCCAAAAACCTTTTAACTTTGAACTACTGGAAGTAAC
TATAAGAAGGGCACTTAAAGAGAAAAGACTGGAGGAGGAAAACAGGACGTTAAAGAGCTTCCTCTTTAAGGAAAAGGAAG
AAGATTACCTGCTGGAAACCAGAAGTCCAAAGTTCAGGGAAGTTTTAGAAATAGCGAGGAGGATTGCAAATACAGACCTT
CCCGTGCTCATACGCGGAGAGACGGGAGTGGGGAAGGAAGTTCTTGCTAAATATATACACACTATTTCAAATAGGAAGGA
CAAACCTTTCGTGGTAGTGGATTGCACCTCTATACCCGAGCACCTCTTTGAGAGCGAACTCTTTGGATACGAAAAGGGAG
CCTTTACGGGGGCAAATACTAGAAAACTAGGACTTGTTGAACTCGCAAATGGCGGAACGCTCTTTTTTGACGAAATAGGA
GAAATGCCTCTCTCAATTCAAGCAAAGCTCCTGAGATTTATAGAAACTAGAAAGTTTAGAAGGGTAGGAGGTTTAAAGGA
TCTAGAAGTAGATGTCAAAATAATTTGCGCTACGAATAAGGATTTATACGAGAAGTCAAAGAGAGGAGAGTTCAGAGAAG
ACCTCTATTTTCGTATAAACACAGTGGAAATCGAAATCCCTCCTCTCAGGGAAAGAAAGGAAGACATACCCCTCCTCGTG
GAGTTTTTCCTGAAGAAATATGGGAAGAAGATCAAAAAAGAAACCTTAAACGAGCTTATAAATTACCCCTGGGAGGGAAA
CGTAAGGGAACTTAAGAACGTAATAGAGAGGGCATGCATACTCTCAACGGGTGAGTATATTGACGAGGCGATATGTCTCA
GTAAGAAAAGCGTGAGCTGTGTGGAAAAAATGATGGAAAAACTCCCAAGTCTTGAAGAGCTTGAAGGGATGTACCTCAAG
TTTCTTTACGAAAAACTGGAAGGTGATGTGGACAAAATTGCCGTTATTCTCGGCTGTAGCAGGAGAACCGTCTTCAGAAA
GTTAAAGAAGTTAAGAGAGGGGAAGGTGCACTTCAAAAATGCTTCCCTTTCCGGGGGCACTCCTTAA

Upstream 100 bases:

>100_bases
CCCAGAGGAGAGGCGTATCAGGACTTACATTTACTTCGTACATTTTTCCGTTTACTTTTAAAAGCATTCCTACCTCCATA
AGTTTTAAATTTAATTGATA

Downstream 100 bases:

>100_bases
GTTTATTTTTCCCCCGTAGCTCTTTACAATGTCGTTCACTATGGCAAGTCCCAGTCCACTCCCTTCCCTCTTGTCTTTCC
CGTGATAAAAGGGCAGGAAT

Product: NtrC family transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MILLVEDDDNLRELLKKKLEEHFVVETAKDGKTAREKLSKNNYDVVLLDIRLPDVDGTELLKEFSTSGVKFIVITGYGDV
KTAVQCVKLGAYDFIQKPFNFELLEVTIRRALKEKRLEEENRTLKSFLFKEKEEDYLLETRSPKFREVLEIARRIANTDL
PVLIRGETGVGKEVLAKYIHTISNRKDKPFVVVDCTSIPEHLFESELFGYEKGAFTGANTRKLGLVELANGGTLFFDEIG
EMPLSIQAKLLRFIETRKFRRVGGLKDLEVDVKIICATNKDLYEKSKRGEFREDLYFRINTVEIEIPPLRERKEDIPLLV
EFFLKKYGKKIKKETLNELINYPWEGNVRELKNVIERACILSTGEYIDEAICLSKKSVSCVEKMMEKLPSLEELEGMYLK
FLYEKLEGDVDKIAVILGCSRRTVFRKLKKLREGKVHFKNASLSGGTP

Sequences:

>Translated_448_residues
MILLVEDDDNLRELLKKKLEEHFVVETAKDGKTAREKLSKNNYDVVLLDIRLPDVDGTELLKEFSTSGVKFIVITGYGDV
KTAVQCVKLGAYDFIQKPFNFELLEVTIRRALKEKRLEEENRTLKSFLFKEKEEDYLLETRSPKFREVLEIARRIANTDL
PVLIRGETGVGKEVLAKYIHTISNRKDKPFVVVDCTSIPEHLFESELFGYEKGAFTGANTRKLGLVELANGGTLFFDEIG
EMPLSIQAKLLRFIETRKFRRVGGLKDLEVDVKIICATNKDLYEKSKRGEFREDLYFRINTVEIEIPPLRERKEDIPLLV
EFFLKKYGKKIKKETLNELINYPWEGNVRELKNVIERACILSTGEYIDEAICLSKKSVSCVEKMMEKLPSLEELEGMYLK
FLYEKLEGDVDKIAVILGCSRRTVFRKLKKLREGKVHFKNASLSGGTP
>Mature_448_residues
MILLVEDDDNLRELLKKKLEEHFVVETAKDGKTAREKLSKNNYDVVLLDIRLPDVDGTELLKEFSTSGVKFIVITGYGDV
KTAVQCVKLGAYDFIQKPFNFELLEVTIRRALKEKRLEEENRTLKSFLFKEKEEDYLLETRSPKFREVLEIARRIANTDL
PVLIRGETGVGKEVLAKYIHTISNRKDKPFVVVDCTSIPEHLFESELFGYEKGAFTGANTRKLGLVELANGGTLFFDEIG
EMPLSIQAKLLRFIETRKFRRVGGLKDLEVDVKIICATNKDLYEKSKRGEFREDLYFRINTVEIEIPPLRERKEDIPLLV
EFFLKKYGKKIKKETLNELINYPWEGNVRELKNVIERACILSTGEYIDEAICLSKKSVSCVEKMMEKLPSLEELEGMYLK
FLYEKLEGDVDKIAVILGCSRRTVFRKLKKLREGKVHFKNASLSGGTP

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=448, Percent_Identity=39.5089285714286, Blast_Score=338, Evalue=6e-94,
Organism=Escherichia coli, GI1790437, Length=441, Percent_Identity=37.6417233560091, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1788905, Length=447, Percent_Identity=36.9127516778523, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1790299, Length=467, Percent_Identity=34.0471092077088, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI87082117, Length=262, Percent_Identity=43.8931297709924, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789233, Length=308, Percent_Identity=42.2077922077922, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789087, Length=334, Percent_Identity=40.4191616766467, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1786524, Length=313, Percent_Identity=39.6166134185303, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87081872, Length=224, Percent_Identity=45.9821428571429, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1787583, Length=303, Percent_Identity=39.2739273927393, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI87082152, Length=215, Percent_Identity=45.5813953488372, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1789828, Length=283, Percent_Identity=32.5088339222615, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI87081858, Length=299, Percent_Identity=29.7658862876254, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1786784, Length=115, Percent_Identity=33.9130434782609, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51645; Mature: 51645

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLVEDDDNLRELLKKKLEEHFVVETAKDGKTAREKLSKNNYDVVLLDIRLPDVDGTEL
CEEEEECCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHH
LKEFSTSGVKFIVITGYGDVKTAVQCVKLGAYDFIQKPFNFELLEVTIRRALKEKRLEEE
HHHHCCCCEEEEEEECCCCHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
NRTLKSFLFKEKEEDYLLETRSPKFREVLEIARRIANTDLPVLIRGETGVGKEVLAKYIH
HHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHH
TISNRKDKPFVVVDCTSIPEHLFESELFGYEKGAFTGANTRKLGLVELANGGTLFFDEIG
HHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEHHHHC
EMPLSIQAKLLRFIETRKFRRVGGLKDLEVDVKIICATNKDLYEKSKRGEFREDLYFRIN
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHCCCCCCCCEEEEE
TVEIEIPPLRERKEDIPLLVEFFLKKYGKKIKKETLNELINYPWEGNVRELKNVIERACI
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LSTGEYIDEAICLSKKSVSCVEKMMEKLPSLEELEGMYLKFLYEKLEGDVDKIAVILGCS
HCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHEEHHHCCC
RRTVFRKLKKLREGKVHFKNASLSGGTP
HHHHHHHHHHHHCCCEEEECCCCCCCCC
>Mature Secondary Structure
MILLVEDDDNLRELLKKKLEEHFVVETAKDGKTAREKLSKNNYDVVLLDIRLPDVDGTEL
CEEEEECCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHH
LKEFSTSGVKFIVITGYGDVKTAVQCVKLGAYDFIQKPFNFELLEVTIRRALKEKRLEEE
HHHHCCCCEEEEEEECCCCHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
NRTLKSFLFKEKEEDYLLETRSPKFREVLEIARRIANTDLPVLIRGETGVGKEVLAKYIH
HHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHH
TISNRKDKPFVVVDCTSIPEHLFESELFGYEKGAFTGANTRKLGLVELANGGTLFFDEIG
HHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEHHHHC
EMPLSIQAKLLRFIETRKFRRVGGLKDLEVDVKIICATNKDLYEKSKRGEFREDLYFRIN
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHCCCCCCCCEEEEE
TVEIEIPPLRERKEDIPLLVEFFLKKYGKKIKKETLNELINYPWEGNVRELKNVIERACI
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LSTGEYIDEAICLSKKSVSCVEKMMEKLPSLEELEGMYLKFLYEKLEGDVDKIAVILGCS
HCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHEEHHHCCC
RRTVFRKLKKLREGKVHFKNASLSGGTP
HHHHHHHHHHHHCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]