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The map label for this gene is cynS

Identifier: 15605770

GI number: 15605770

Start: 130079

End: 130528

Strand: Direct

Name: cynS

Synonym: aq_212

Alternate gene names: 15605770

Gene position: 130079-130528 (Clockwise)

Preceding gene: 15605769

Following gene: 15605771

Centisome position: 8.38

GC content: 46.0

Gene sequence:

>450_bases
ATGAGGAGCGATATAGGAAGGCTCTCTAAGTACTTAATTGAAAGGAAAAAGAATCTTGGTCTTACGTGGGAAGATGTAAG
CAGAAAGCTTGGGAAAAGCCCCGTTTATTGTGCAATGCTCTTCTATGGATACGCTCAGGCCGACGATGAAGAGGTTAAAG
CTGTAGCTGAGCTTTTGAATCTGGAAGAGAAGGAGCTCGCGGAGCTGAAAGATGCCCCATACAGAGAACCTCAGCAACCC
GTCCCGCCTACGGATCCCTTCGTTTACAGGCTCTATGAAGTTGTTATTCTCTACGGACCGGCTTTAAAAGATGTAGCCCA
CGAAATGTTCGGGGACGGGATAATGAGTGCTATAGATATGAGCGTTGAGCTTGAAAAAGTTGAGCAGGAGGGGGCTGAGC
GTATGGTTTTAACCTTTAATGGCAAATGGCTGAAGTACAGGAAGTTTTAA

Upstream 100 bases:

>100_bases
GGAAGTTCTCAAAGCATGGGAAGAGGCGTACGATTTTCTTGCTAAAACGCTTATAACCCTAGAGAAAAAACTTTATAGCC
AGCCTTAGGGAGGTCTAATT

Downstream 100 bases:

>100_bases
AGGGAGGATTTAGAAATGGAAGAGCTCTTGGCAATTGTCAGGAAGGAAAAGTCTTACGATGTGATGAAATCCTTATCTGA
GGCTGAGATACCTTACGTTT

Product: cyanate hydratase

Products: NA

Alternate protein names: Cyanase; Cyanate hydrolase; Cyanate lyase

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRSDIGRLSKYLIERKKNLGLTWEDVSRKLGKSPVYCAMLFYGYAQADDEEVKAVAELLNLEEKELAELKDAPYREPQQP
VPPTDPFVYRLYEVVILYGPALKDVAHEMFGDGIMSAIDMSVELEKVEQEGAERMVLTFNGKWLKYRKF

Sequences:

>Translated_149_residues
MRSDIGRLSKYLIERKKNLGLTWEDVSRKLGKSPVYCAMLFYGYAQADDEEVKAVAELLNLEEKELAELKDAPYREPQQP
VPPTDPFVYRLYEVVILYGPALKDVAHEMFGDGIMSAIDMSVELEKVEQEGAERMVLTFNGKWLKYRKF
>Mature_149_residues
MRSDIGRLSKYLIERKKNLGLTWEDVSRKLGKSPVYCAMLFYGYAQADDEEVKAVAELLNLEEKELAELKDAPYREPQQP
VPPTDPFVYRLYEVVILYGPALKDVAHEMFGDGIMSAIDMSVELEKVEQEGAERMVLTFNGKWLKYRKF

Specific function: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide

COG id: COG1513

COG function: function code P; Cyanate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyanase family

Homologues:

Organism=Escherichia coli, GI1786535, Length=155, Percent_Identity=31.6129032258064, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYNS_AQUAE (O66587)

Other databases:

- EMBL:   AE000657
- PIR:   G70319
- RefSeq:   NP_213147.1
- ProteinModelPortal:   O66587
- SMR:   O66587
- GeneID:   1192821
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_212
- NMPDR:   fig|224324.1.peg.162
- HOGENOM:   HBG317643
- OMA:   QTIPLRG
- ProtClustDB:   PRK02866
- BioCyc:   AAEO224324:AQ_212-MONOMER
- BRENDA:   4.2.1.104
- HAMAP:   MF_00535
- InterPro:   IPR008076
- InterPro:   IPR003712
- InterPro:   IPR001387
- InterPro:   IPR010982
- Gene3D:   G3DSA:3.30.1160.10
- PIRSF:   PIRSF001263
- PRINTS:   PR01693
- SMART:   SM00530
- TIGRFAMs:   TIGR00673

Pfam domain/function: PF02560 Cyanate_lyase; PF01381 HTH_3; SSF55234 Cyanate_lyase_C; SSF47413 Lambda_like_DNA

EC number: =4.2.1.104

Molecular weight: Translated: 17201; Mature: 17201

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50943 HTH_CROC1

Important sites: ACT_SITE 90-90 ACT_SITE 93-93 ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSDIGRLSKYLIERKKNLGLTWEDVSRKLGKSPVYCAMLFYGYAQADDEEVKAVAELLN
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHC
LEEKELAELKDAPYREPQQPVPPTDPFVYRLYEVVILYGPALKDVAHEMFGDGIMSAIDM
CCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SVELEKVEQEGAERMVLTFNGKWLKYRKF
HHHHHHHHHCCCCEEEEEECCCEEEEECC
>Mature Secondary Structure
MRSDIGRLSKYLIERKKNLGLTWEDVSRKLGKSPVYCAMLFYGYAQADDEEVKAVAELLN
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHC
LEEKELAELKDAPYREPQQPVPPTDPFVYRLYEVVILYGPALKDVAHEMFGDGIMSAIDM
CCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SVELEKVEQEGAERMVLTFNGKWLKYRKF
HHHHHHHHHCCCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320