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The map label for this gene is srlR [H]

Identifier: 15603829

GI number: 15603829

Start: 2203645

End: 2204409

Strand: Reverse

Name: srlR [H]

Synonym: PM1964

Alternate gene names: 15603829

Gene position: 2204409-2203645 (Counterclockwise)

Preceding gene: 15603830

Following gene: 15603828

Centisome position: 97.65

GC content: 35.16

Gene sequence:

>765_bases
ATGAAACCTTTTGAAAGACAGCAGCATATTTTTAATTATTTAATGACAAATGGAAAAACCAAAGTCGATGAATTAGCGAG
TCATTTTCATCTCACTGGTGCAACAATTCGTAAAGATCTCACTGCGTTGGAAAAACAAAATAAAGTCTTAAGAACCTATG
GTAGTGTCGTCGTTACCCAAAAAGATCTTGAACAAGACCCGCCTATTGATTTTAAAACCAATGTCAACCTCAGCCAAAAA
CAACGAATTGGAAAAAAAGCCGCCACCCTCATCAACGAAGGAGATTCTATTATCTTTGATGCTGGTAGTACTGTGCTACA
AATTATCCCCAATTTAACCACATTTGACAACTTGTCTATCATGACAAATAGCTTAACGATCTTTAATGCTGTTCTACAAC
TCAATAAATCCTATAACTTATTAATGTCTGGCGGATCATTCCGTGAAAAATCAGCGTCGTTTCATGGTTATTTTGCAGAA
TCTGTTTTCATTGGTTCAACTTTTGATACGTTATTTATTGGTACTGATGGTCTTGATCTTGACGTTGGATTAACGACGTT
TAATGAAGTTTATCGCGTCAGTTCATTAATGTGTAACGCCGCCAAAAAAATCATTGTCCTTGCTGATTCAAGTAAATTTG
GACGAAAAACACCAAATATCGTCTGTGGCTTAGAAAAAATCCATACTATTGTTACTGATGATAAGTTACCGACAGAAATG
AAAGACAAACTCATCGAAAAAGGTATTGAGGTTTTAATTGTTTAG

Upstream 100 bases:

>100_bases
CAGATGCACGATTACCCACACGACTAGATGTGATCAAAAAACTGGAAGACGATTAGCAAGATAACACAAAAATATGCTTG
CTAAGATATAGGAACAAAAC

Downstream 100 bases:

>100_bases
TTTAGCTTAGCTAAACCTTTATCACGGGCATGTGTGATAACACGCGTCTTACTCAAGACGTGCTCAAACATCTCACTTAT
GCAATAAAAAGTGGTATTTC

Product: DNA-bindng transcriptional repressor SrlR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKPFERQQHIFNYLMTNGKTKVDELASHFHLTGATIRKDLTALEKQNKVLRTYGSVVVTQKDLEQDPPIDFKTNVNLSQK
QRIGKKAATLINEGDSIIFDAGSTVLQIIPNLTTFDNLSIMTNSLTIFNAVLQLNKSYNLLMSGGSFREKSASFHGYFAE
SVFIGSTFDTLFIGTDGLDLDVGLTTFNEVYRVSSLMCNAAKKIIVLADSSKFGRKTPNIVCGLEKIHTIVTDDKLPTEM
KDKLIEKGIEVLIV

Sequences:

>Translated_254_residues
MKPFERQQHIFNYLMTNGKTKVDELASHFHLTGATIRKDLTALEKQNKVLRTYGSVVVTQKDLEQDPPIDFKTNVNLSQK
QRIGKKAATLINEGDSIIFDAGSTVLQIIPNLTTFDNLSIMTNSLTIFNAVLQLNKSYNLLMSGGSFREKSASFHGYFAE
SVFIGSTFDTLFIGTDGLDLDVGLTTFNEVYRVSSLMCNAAKKIIVLADSSKFGRKTPNIVCGLEKIHTIVTDDKLPTEM
KDKLIEKGIEVLIV
>Mature_254_residues
MKPFERQQHIFNYLMTNGKTKVDELASHFHLTGATIRKDLTALEKQNKVLRTYGSVVVTQKDLEQDPPIDFKTNVNLSQK
QRIGKKAATLINEGDSIIFDAGSTVLQIIPNLTTFDNLSIMTNSLTIFNAVLQLNKSYNLLMSGGSFREKSASFHGYFAE
SVFIGSTFDTLFIGTDGLDLDVGLTTFNEVYRVSSLMCNAAKKIIVLADSSKFGRKTPNIVCGLEKIHTIVTDDKLPTEM
KDKLIEKGIEVLIV

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=253, Percent_Identity=54.5454545454545, Blast_Score=287, Evalue=5e-79,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=33.7301587301587, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=27.2727272727273, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=25, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=26.4957264957265, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082344, Length=259, Percent_Identity=24.7104247104247, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787540, Length=234, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=25.2136752136752, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790753, Length=252, Percent_Identity=24.2063492063492, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790635, Length=258, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1787063, Length=230, Percent_Identity=25.2173913043478, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28248; Mature: 28248

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFERQQHIFNYLMTNGKTKVDELASHFHLTGATIRKDLTALEKQNKVLRTYGSVVVTQ
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEH
KDLEQDPPIDFKTNVNLSQKQRIGKKAATLINEGDSIIFDAGSTVLQIIPNLTTFDNLSI
HHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCCCCHH
MTNSLTIFNAVLQLNKSYNLLMSGGSFREKSASFHGYFAESVFIGSTFDTLFIGTDGLDL
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCEE
DVGLTTFNEVYRVSSLMCNAAKKIIVLADSSKFGRKTPNIVCGLEKIHTIVTDDKLPTEM
EECHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECHHHHHHHHCCCCCCHHH
KDKLIEKGIEVLIV
HHHHHHCCCEEEEC
>Mature Secondary Structure
MKPFERQQHIFNYLMTNGKTKVDELASHFHLTGATIRKDLTALEKQNKVLRTYGSVVVTQ
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEH
KDLEQDPPIDFKTNVNLSQKQRIGKKAATLINEGDSIIFDAGSTVLQIIPNLTTFDNLSI
HHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCCCCHH
MTNSLTIFNAVLQLNKSYNLLMSGGSFREKSASFHGYFAESVFIGSTFDTLFIGTDGLDL
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCEE
DVGLTTFNEVYRVSSLMCNAAKKIIVLADSSKFGRKTPNIVCGLEKIHTIVTDDKLPTEM
EECHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECHHHHHHHHCCCCCCHHH
KDKLIEKGIEVLIV
HHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]