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The map label for this gene is yjjG [H]

Identifier: 15603746

GI number: 15603746

Start: 2122733

End: 2123404

Strand: Direct

Name: yjjG [H]

Synonym: PM1881

Alternate gene names: 15603746

Gene position: 2122733-2123404 (Clockwise)

Preceding gene: 15603745

Following gene: 15603750

Centisome position: 94.03

GC content: 37.8

Gene sequence:

>672_bases
ATGAAATATCAATGGATTTTTTTTGATGCAGATGAAACCTTGTTTTCATTTGATGCTTTTGCAGGATTGCAGAAATTGTT
TTCAGATTATGGTGTTGATTTTCAACAAAGTGATTTTACAGAATTTCAACGTGTGAATAAGCCACTTTGGGTGCAATATC
AACAGGCTGAAATTAGCGCAGAACAATTACAGGTCACCCGTTTTGCTAGTTGGGCGAAGCGTTTAAATAAAAATCCAGTA
GAGCTGAACGATCATTACTTAATCGCAATGGCAGACATTTGTAAACCGTTGGAAAACGTAGTGGAAACCTTAACCGTGTT
AAAAGAACAAGTGAATTTAGGCATCATCACCAATGGGTTTACGACATTACAGAAATTGCGTTTAGAAAAAACAGGCTTAA
GTGATTGGTTTCAATTTGTCACCATTTCGGAAGAAGTGGGGATCGCAAAACCGGATCCTCGGATTTTTGAACACAGTTTA
GCCTTAGCAAAAGTGACAGATCGTCGCCAAGTGTTAATGGTGGGGGATAATTTAGATTCGGATATTTTAGGCGGGCATAA
TGCGAATTTAGATACCTGTTGGTTGCATTATGATCGTGAAAATCACAGTGATATTCAGCCAACGTACAGTATTGATCGTT
TTGATCAATTATTGGAAATTGTGTCAGCCTAG

Upstream 100 bases:

>100_bases
TTAAAAAAGCATACCCACAAGCCGATGCGCTCTTTCAGCTCATTAAAACCTGTCATGATGGACAGGCGTTACGCATGAAA
ATAGACGGAGTTATGAACTA

Downstream 100 bases:

>100_bases
TGTTGAGTGTATTGTTATCCAAAAATTTTTAAAAAAATAACCGCACTTTTTGCAAGAGCATGCTTTGATGGCGAAGTCTA
AAAGTGCGGTGTGTTTTATC

Product: nucleotidase

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKYQWIFFDADETLFSFDAFAGLQKLFSDYGVDFQQSDFTEFQRVNKPLWVQYQQAEISAEQLQVTRFASWAKRLNKNPV
ELNDHYLIAMADICKPLENVVETLTVLKEQVNLGIITNGFTTLQKLRLEKTGLSDWFQFVTISEEVGIAKPDPRIFEHSL
ALAKVTDRRQVLMVGDNLDSDILGGHNANLDTCWLHYDRENHSDIQPTYSIDRFDQLLEIVSA

Sequences:

>Translated_223_residues
MKYQWIFFDADETLFSFDAFAGLQKLFSDYGVDFQQSDFTEFQRVNKPLWVQYQQAEISAEQLQVTRFASWAKRLNKNPV
ELNDHYLIAMADICKPLENVVETLTVLKEQVNLGIITNGFTTLQKLRLEKTGLSDWFQFVTISEEVGIAKPDPRIFEHSL
ALAKVTDRRQVLMVGDNLDSDILGGHNANLDTCWLHYDRENHSDIQPTYSIDRFDQLLEIVSA
>Mature_223_residues
MKYQWIFFDADETLFSFDAFAGLQKLFSDYGVDFQQSDFTEFQRVNKPLWVQYQQAEISAEQLQVTRFASWAKRLNKNPV
ELNDHYLIAMADICKPLENVVETLTVLKEQVNLGIITNGFTTLQKLRLEKTGLSDWFQFVTISEEVGIAKPDPRIFEHSL
ALAKVTDRRQVLMVGDNLDSDILGGHNANLDTCWLHYDRENHSDIQPTYSIDRFDQLLEIVSA

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Escherichia coli, GI1790833, Length=223, Percent_Identity=52.4663677130045, Blast_Score=250, Evalue=7e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 25774; Mature: 25774

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQWIFFDADETLFSFDAFAGLQKLFSDYGVDFQQSDFTEFQRVNKPLWVQYQQAEISA
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEHHHHCCH
EQLQVTRFASWAKRLNKNPVELNDHYLIAMADICKPLENVVETLTVLKEQVNLGIITNGF
HHHHHHHHHHHHHHHCCCCCEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEECCH
TTLQKLRLEKTGLSDWFQFVTISEEVGIAKPDPRIFEHSLALAKVTDRRQVLMVGDNLDS
HHHHHHHHHHCCHHHHHHHHEEHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCC
DILGGHNANLDTCWLHYDRENHSDIQPTYSIDRFDQLLEIVSA
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKYQWIFFDADETLFSFDAFAGLQKLFSDYGVDFQQSDFTEFQRVNKPLWVQYQQAEISA
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEHHHHCCH
EQLQVTRFASWAKRLNKNPVELNDHYLIAMADICKPLENVVETLTVLKEQVNLGIITNGF
HHHHHHHHHHHHHHHCCCCCEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEECCH
TTLQKLRLEKTGLSDWFQFVTISEEVGIAKPDPRIFEHSLALAKVTDRRQVLMVGDNLDS
HHHHHHHHHHCCHHHHHHHHEEHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCC
DILGGHNANLDTCWLHYDRENHSDIQPTYSIDRFDQLLEIVSA
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]