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The map label for this gene is hemY [H]

Identifier: 15603680

GI number: 15603680

Start: 2045088

End: 2046353

Strand: Direct

Name: hemY [H]

Synonym: PM1815

Alternate gene names: 15603680

Gene position: 2045088-2046353 (Clockwise)

Preceding gene: 15603679

Following gene: 15603683

Centisome position: 90.59

GC content: 39.26

Gene sequence:

>1266_bases
ATGTTTAGAGTGCTATTTTTAATGCTGGTGTTACTAGCAGGCTTAATTGCAGGACCGTATTTATCGGGTAAACAAGGCTA
TGTCTTGATTGAAACGAACAGCTACAATATTGAAATGTCCATTACGATGTTAGTGGTGTTTTTTGTGATCGCCATGGCAG
TAATTTATGGAATTGAAGTTATTGTGACGCGTTTTTGTCGTTTAAGTAGCGATACTTATCATTGGTTTTCTCGTCGTAAA
CGTGCCAAAGCACAAAAACAAACCCTCGAAGGGTTGATGCGCATGAATGAGGGCGATTATTCAAAAGCAGAGAAATTAAT
CGGAAAAAATGCGAAACATTCGGAAGAGCCGATCTTGAACTTCATTACTGCCGCAGAAGCGGCACAACAACGTGGTGATG
AGTTTTCCGCTAACCGTTATTTGTTAGAAGCAACGGAGTTAGCCGGGTCCGATAATTTAATGGTTGAGTTAGCGAGAACG
CGAATTCTATTGCAACAAGGAAAATTACCTGCTGCACGAAGTTCGGTTGATAGTTTGTTAGTGATGACGAACCGTAATAA
AGAAGTACTCAAGCTAGCAGTCGACATTTATTTAAAATCAAAAGCGTATTTAGCTCTAGATAAGATACTTGACCAAATTG
AAAGTGCGGGATTATATACAGCGCAAGATTTTATCCAATTGCAACGTCAAGTGGAAAATGGCTTATTAGATGAGAAAATG
AACGAAGAAGGTGTAGATGGCTTATTGACTTGGTGGAATGATCAGCCACGTAAACGTCGTCATGATCTTTCAGTTAAAAT
TGCATTAATTCAGCGTTTAATTGATTGCAATGACCATGAAACTGCTTATGAATTGACACTGGAAGCTTTGAAGAAAGTGG
AAGATCAAAGCCCAGAAAATCGTTTGTTGTGTACGCAAATTGCACGTTTGCAACCGGAAGATAATAGTAAGTTAATTAAA
CTGATGGAGAAAAGAGCAAATAAAGCCATAGAAGGTGAGCATTGCTGTATTTATCGCGCCTTGGGGTATTTGTATGTGCG
TAATAATGATTTTACCCAAGCTAGCCAAGCGTTCAAACATGTTGTTGCCAATAAAGCACAACTTGAAGCAACCGATGTCA
ATATGGCGGCTTATGTATTCGAACAAGTAGGGGAAAATGCTTTAGCGCAGCAAGTGCGTGAGGAAAGTTTAAAAGAAACG
ATGGCAGTTTCTTCACTTACACATTCTCAACCAGAAGAACCGCCGGTGCTTTTAGAAAGTAAATAA

Upstream 100 bases:

>100_bases
GATCGAACTTTCCGTGGATAAGGCGTTAGTTGAGGAAACAACAGAGAGTGCTCCTTCGAGTGACGCTTCGACGGCAGAAC
AACAGTAGAGGAAATAGATT

Downstream 100 bases:

>100_bases
ACTTGTTGATTGCTAGATTAGGTAGCCCTTCATACTGCAAATTCAGTATTGAAGGGCTATTTTTTTAGAAACGATATTAT
TTATTTTGATGAGATTATTC

Product: HemY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MFRVLFLMLVLLAGLIAGPYLSGKQGYVLIETNSYNIEMSITMLVVFFVIAMAVIYGIEVIVTRFCRLSSDTYHWFSRRK
RAKAQKQTLEGLMRMNEGDYSKAEKLIGKNAKHSEEPILNFITAAEAAQQRGDEFSANRYLLEATELAGSDNLMVELART
RILLQQGKLPAARSSVDSLLVMTNRNKEVLKLAVDIYLKSKAYLALDKILDQIESAGLYTAQDFIQLQRQVENGLLDEKM
NEEGVDGLLTWWNDQPRKRRHDLSVKIALIQRLIDCNDHETAYELTLEALKKVEDQSPENRLLCTQIARLQPEDNSKLIK
LMEKRANKAIEGEHCCIYRALGYLYVRNNDFTQASQAFKHVVANKAQLEATDVNMAAYVFEQVGENALAQQVREESLKET
MAVSSLTHSQPEEPPVLLESK

Sequences:

>Translated_421_residues
MFRVLFLMLVLLAGLIAGPYLSGKQGYVLIETNSYNIEMSITMLVVFFVIAMAVIYGIEVIVTRFCRLSSDTYHWFSRRK
RAKAQKQTLEGLMRMNEGDYSKAEKLIGKNAKHSEEPILNFITAAEAAQQRGDEFSANRYLLEATELAGSDNLMVELART
RILLQQGKLPAARSSVDSLLVMTNRNKEVLKLAVDIYLKSKAYLALDKILDQIESAGLYTAQDFIQLQRQVENGLLDEKM
NEEGVDGLLTWWNDQPRKRRHDLSVKIALIQRLIDCNDHETAYELTLEALKKVEDQSPENRLLCTQIARLQPEDNSKLIK
LMEKRANKAIEGEHCCIYRALGYLYVRNNDFTQASQAFKHVVANKAQLEATDVNMAAYVFEQVGENALAQQVREESLKET
MAVSSLTHSQPEEPPVLLESK
>Mature_421_residues
MFRVLFLMLVLLAGLIAGPYLSGKQGYVLIETNSYNIEMSITMLVVFFVIAMAVIYGIEVIVTRFCRLSSDTYHWFSRRK
RAKAQKQTLEGLMRMNEGDYSKAEKLIGKNAKHSEEPILNFITAAEAAQQRGDEFSANRYLLEATELAGSDNLMVELART
RILLQQGKLPAARSSVDSLLVMTNRNKEVLKLAVDIYLKSKAYLALDKILDQIESAGLYTAQDFIQLQRQVENGLLDEKM
NEEGVDGLLTWWNDQPRKRRHDLSVKIALIQRLIDCNDHETAYELTLEALKKVEDQSPENRLLCTQIARLQPEDNSKLIK
LMEKRANKAIEGEHCCIYRALGYLYVRNNDFTQASQAFKHVVANKAQLEATDVNMAAYVFEQVGENALAQQVREESLKET
MAVSSLTHSQPEEPPVLLESK

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790234, Length=390, Percent_Identity=37.1794871794872, Blast_Score=275, Evalue=5e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07219 HemY_N [H]

EC number: NA

Molecular weight: Translated: 47774; Mature: 47774

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRVLFLMLVLLAGLIAGPYLSGKQGYVLIETNSYNIEMSITMLVVFFVIAMAVIYGIEV
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHH
IVTRFCRLSSDTYHWFSRRKRAKAQKQTLEGLMRMNEGDYSKAEKLIGKNAKHSEEPILN
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHH
FITAAEAAQQRGDEFSANRYLLEATELAGSDNLMVELARTRILLQQGKLPAARSSVDSLL
HHHHHHHHHHCCCCCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHEE
VMTNRNKEVLKLAVDIYLKSKAYLALDKILDQIESAGLYTAQDFIQLQRQVENGLLDEKM
EEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHC
NEEGVDGLLTWWNDQPRKRRHDLSVKIALIQRLIDCNDHETAYELTLEALKKVEDQSPEN
CCCCCCHHHCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
RLLCTQIARLQPEDNSKLIKLMEKRANKAIEGEHCCIYRALGYLYVRNNDFTQASQAFKH
CHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCEEEEECCCHHHHHHHHHH
VVANKAQLEATDVNMAAYVFEQVGENALAQQVREESLKETMAVSSLTHSQPEEPPVLLES
HHHCCHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC
K
C
>Mature Secondary Structure
MFRVLFLMLVLLAGLIAGPYLSGKQGYVLIETNSYNIEMSITMLVVFFVIAMAVIYGIEV
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHH
IVTRFCRLSSDTYHWFSRRKRAKAQKQTLEGLMRMNEGDYSKAEKLIGKNAKHSEEPILN
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHH
FITAAEAAQQRGDEFSANRYLLEATELAGSDNLMVELARTRILLQQGKLPAARSSVDSLL
HHHHHHHHHHCCCCCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHEE
VMTNRNKEVLKLAVDIYLKSKAYLALDKILDQIESAGLYTAQDFIQLQRQVENGLLDEKM
EEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHC
NEEGVDGLLTWWNDQPRKRRHDLSVKIALIQRLIDCNDHETAYELTLEALKKVEDQSPEN
CCCCCCHHHCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
RLLCTQIARLQPEDNSKLIKLMEKRANKAIEGEHCCIYRALGYLYVRNNDFTQASQAFKH
CHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCEEEEECCCHHHHHHHHHH
VVANKAQLEATDVNMAAYVFEQVGENALAQQVREESLKETMAVSSLTHSQPEEPPVLLES
HHHCCHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]