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The map label for this gene is ptsG [H]

Identifier: 15603617

GI number: 15603617

Start: 1974589

End: 1975941

Strand: Direct

Name: ptsG [H]

Synonym: PM1752

Alternate gene names: 15603617

Gene position: 1974589-1975941 (Clockwise)

Preceding gene: 15603612

Following gene: 15603618

Centisome position: 87.47

GC content: 41.54

Gene sequence:

>1353_bases
GTGTTACAAGGCATTTTCCAAATTATGTCTGCCGCAGGCAGTGTGGTTTTTGCTAATCTGGCGTTATTACTTTGTATCGG
TTTAGGCATTGGTCTGGCTAAACGTGATAAAGGGGTCGCTGCATTAGCGGCAGTAGTCGGTTATTTAATCATGACGGGCA
CCATTAATGCGTTAATCAGTATTTTTTCACCAGAAGTAAAAGGGATTGATACGGGGGTGATTGGCTCCTTAGTGATGGGA
TTATTAACGGTGAAATTACATAATCGTTACCACAACATCCAATTACCACAAATTTTAGGGTTCTTTGGCGGATCGCGATT
TGTTCCTATTGTTACCGCGTTTGCGGCAATTTTTGTTGGTTTCCTCTTTTTCCTTATTTGGCCAACGTTCCAAGGTTGGT
TAGTATCCGCGGGTGAGGGTATTGCCTCTATGGGCGCAATTGGGACGTTTTTTTACGGCTTTTTGATGCGTTTGAGTGGA
GCGGTGGGATTACATCACATGATTTATCCGCTCTTTTGGTATACAGAGTTAGGGGGAACGGAAATTGTAAACGGTGAAAC
CATTATCGGGGCACAAAAAATCTTTTTTGCCCAATTAGCTGATCCGAACCATCAAGGGTTATTCACTGAAGGGACTCGCT
TCTTCGCGGGGCGTTTCGATACCATGATGTTTGGCTTACCCGCCGCCTGTTTGGCAATGTATCACTGTGTACCTAAAGCA
CGTCGTGGTTTGATTGGTGGTTTGTTTTTAGGGGCCGCCTTAACGTCGTTTATTACAGGCATCACAGAACCTATCGAATT
TATGTTCTTATTTGTGGCACCTTGGTTGTATGTTTTCCATGCTTTCTTAGATGGTGTTTCATTCTTTATTGCCGATTTCT
TGAATATTTCGATTGGTAATACTTTCTCGGGTGGCTTTATTGATTTCCTTTTATTTGGCATTTTACAGGGGAATGAAAAC
ACAAACTGGATCCTTGTAGTCGTTGTCGGTGTGTTTTGGGCAATGTTATATTACTTTAGCTTCCGCTTTCTGATTACGAA
ATTTGATGTGATGACACCGGGCAGAGCTGAAGAACAGGAAGAGGTAGTTGAATCGACTAACTCTTCGTTAACTGAAAATG
CACATCACATTATTGAGGCATTAGGCAAGGCTGAAAATATTGAACATGTGGATGCTTGTATTACACGTTTACGTGTGAAT
GTCAAAGACGTGAAAGCAGTAGATAAAGCACGTTTAAAAGCATTAGGGGCAATTGATGTTCTTGAAGTTGGTGGAGGTAT
TCAAGCGATTTTTGGGGCAAAAGCGGTGTTATACAAAAGCGAAGTTAACCAAATTTTAGGTAAAGAAGATTAA

Upstream 100 bases:

>100_bases
ACCAATTGCCATTCTACCTGCTGCAGGTTTGCTACTAGGGATTGGTGGCGCATTATCGAATAAAGCGACGGTACAGGCTT
ATCCTGTTTTAGATAACCCC

Downstream 100 bases:

>100_bases
TTTTCTTGTCCAAGATAGCATGCCTCTAAAGTATTTTAGAGGCATTTTTGTTGCGTAGAAATATATTTTGAGATGCCTAT
GGACTTATCTTATGTCCTTG

Product: hypothetical protein

Products: NA

Alternate protein names: EIICBA-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MLQGIFQIMSAAGSVVFANLALLLCIGLGIGLAKRDKGVAALAAVVGYLIMTGTINALISIFSPEVKGIDTGVIGSLVMG
LLTVKLHNRYHNIQLPQILGFFGGSRFVPIVTAFAAIFVGFLFFLIWPTFQGWLVSAGEGIASMGAIGTFFYGFLMRLSG
AVGLHHMIYPLFWYTELGGTEIVNGETIIGAQKIFFAQLADPNHQGLFTEGTRFFAGRFDTMMFGLPAACLAMYHCVPKA
RRGLIGGLFLGAALTSFITGITEPIEFMFLFVAPWLYVFHAFLDGVSFFIADFLNISIGNTFSGGFIDFLLFGILQGNEN
TNWILVVVVGVFWAMLYYFSFRFLITKFDVMTPGRAEEQEEVVESTNSSLTENAHHIIEALGKAENIEHVDACITRLRVN
VKDVKAVDKARLKALGAIDVLEVGGGIQAIFGAKAVLYKSEVNQILGKED

Sequences:

>Translated_450_residues
MLQGIFQIMSAAGSVVFANLALLLCIGLGIGLAKRDKGVAALAAVVGYLIMTGTINALISIFSPEVKGIDTGVIGSLVMG
LLTVKLHNRYHNIQLPQILGFFGGSRFVPIVTAFAAIFVGFLFFLIWPTFQGWLVSAGEGIASMGAIGTFFYGFLMRLSG
AVGLHHMIYPLFWYTELGGTEIVNGETIIGAQKIFFAQLADPNHQGLFTEGTRFFAGRFDTMMFGLPAACLAMYHCVPKA
RRGLIGGLFLGAALTSFITGITEPIEFMFLFVAPWLYVFHAFLDGVSFFIADFLNISIGNTFSGGFIDFLLFGILQGNEN
TNWILVVVVGVFWAMLYYFSFRFLITKFDVMTPGRAEEQEEVVESTNSSLTENAHHIIEALGKAENIEHVDACITRLRVN
VKDVKAVDKARLKALGAIDVLEVGGGIQAIFGAKAVLYKSEVNQILGKED
>Mature_450_residues
MLQGIFQIMSAAGSVVFANLALLLCIGLGIGLAKRDKGVAALAAVVGYLIMTGTINALISIFSPEVKGIDTGVIGSLVMG
LLTVKLHNRYHNIQLPQILGFFGGSRFVPIVTAFAAIFVGFLFFLIWPTFQGWLVSAGEGIASMGAIGTFFYGFLMRLSG
AVGLHHMIYPLFWYTELGGTEIVNGETIIGAQKIFFAQLADPNHQGLFTEGTRFFAGRFDTMMFGLPAACLAMYHCVPKA
RRGLIGGLFLGAALTSFITGITEPIEFMFLFVAPWLYVFHAFLDGVSFFIADFLNISIGNTFSGGFIDFLLFGILQGNEN
TNWILVVVVGVFWAMLYYFSFRFLITKFDVMTPGRAEEQEEVVESTNSSLTENAHHIIEALGKAENIEHVDACITRLRVN
VKDVKAVDKARLKALGAIDVLEVGGGIQAIFGAKAVLYKSEVNQILGKED

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=466, Percent_Identity=40.1287553648069, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1787343, Length=448, Percent_Identity=40.625, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI1786894, Length=446, Percent_Identity=39.0134529147982, Blast_Score=254, Evalue=6e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 48960; Mature: 48960

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA