Click here to switch to the map view.

The map label for this gene is rpoC [H]

Identifier: 15603601

GI number: 15603601

Start: 1952228

End: 1956481

Strand: Reverse

Name: rpoC [H]

Synonym: PM1736

Alternate gene names: 15603601

Gene position: 1956481-1952228 (Counterclockwise)

Preceding gene: 15603602

Following gene: 15603600

Centisome position: 86.67

GC content: 43.98

Gene sequence:

>4254_bases
GTGAAAGACTTAGTTAAGTTTTTAAAAGCACAATCAAAAACAAGTGAAGATTTTGATGTGATCAAAATTGGTTTAGCCTC
ACCGGACATGATCCGTTCTTGGTCATTTGGTGAAGTTAAAAAACCTGAAACCATTAACTACCGCACCTTTAAACCAGAGC
GTGACGGTCTTTTCTGTGCACGTATTTTCGGACCAGTAAAAGATTACGAATGTTTATGTGGTAAATACAAACGCTTAAAA
CACCGTGGTGTGATCTGTGAAAAATGTGGTGTGGAAGTCACTCAAACCAAAGTACGTCGTGAGCGTATGGGTCACATTGA
ACTTGCCTCACCCGTGGCGCACATTTGGTTCTTAAAATCACTGCCGTCCCGTATCGGTTTATTACTTGATATGCCATTAC
GTGATATCGAACGCGTTTTATATTTCGAATCTTATATTGTGATCGAGCCGGGAATGACGGATCTCGATAAAGGTCAGTTA
TTAACCGAAGAACAATATATCGATGCGGAAGATCGTTGGGGCGATGAATTTGACGCGAAAATGGGGGCGGAAGCTATCCA
AGCCTTATTGCGCGATATGGATTTACCGCAAGAATGTGAAAACTTACGTGAAGAATTACAAGAAACGAACTCAGAAACCA
AACGTAAGAAAATCACCAAACGTTTAAAACTGTTAGAAGCCTTTATTCAATCGGGTAACAAGCCTGAATGGATGGTAATG
ACCGTATTACCAGTATTACCACCAGATTTACGTCCATTAGTGCCACTCGATGGTGGTCGTTTTGCGACCTCAGATTTGAA
CGATTTATACCGTCGTGTGATCAACCGTAACAACCGTTTAAAACGTCTTTTAGACTTAATCGCACCAGATATCATCGTGC
GTAACGAAAAACGTATGTTACAAGAATCAGTAGATGCGTTATTAGATAACGGTCGTCGTGGTCGTGCTATTACTGGCTCT
AACCGTCGTCCATTAAAATCACTTGCGGATATGATCAAAGGTAAACAAGGTCGTTTCCGTCAAAACCTATTAGGTAAACG
TGTTGACTATTCAGGTCGTTCGGTAATCACCGTAGGACCATATTTGCACCTACATCAATGTGGTTTACCGAAAAAAATGG
CATTGGAATTATTCCGTCCGTTTATCTATGCAAAATTAGAAAGCCGTGGCTTCGCTTCAACTATTAAAGCCGCGAAGAAA
ATGGTTGAGCGTGAAGATGCGATCGTATGGGATATCTTAGCGGACGTAATTCGCGAGCACCCAATTTTATTAAACCGTGC
ACCAACGTTGCACCGTTTGGGTATCCAAGCCTTTGAACCTTTATTGATCGAAGGTAAAGCGATCCAGTTACACCCACTTG
TTTGTGCGGCGTTCAACGCGGACTTCGACGGTGACCAAATGGCGGTTCACGTGCCATTGACATTAGAAGCACAGTTAGAA
GCGCGTGCATTAATGATGTCAACCAACAACATTTTATCACCTGCAAACGGTGAGCCGATTATCGTTCCTTCACAAGACGT
GGTATTAGGTCTTTACTATATGACCCGTGATAAAGTGAACGGTAAAGGTGAAGGCATGTTGTTACAAGACCCACGTGAAG
CGGAAAAAGCGTATCGCACCGGTCAAGTCGAATTACATTCTCGTGTCAAAGTGCGTATCACAGAATACGTGAAAAATGCG
GTAGGCGAGTTTGAGCCACAAACTAACTTAGTGGATACGACCATTGGTCGTGCGATTCTTTGGATGATCGCACCAAAAGG
AATGCCATTTAGCTTATTTAACCAAACCTTAGGTAAAAAGGCGATTTCTAAGTTAATCAACGAGAGCTATCGTCGCTTAG
GGATGAAACCAAGCGTCTTGTTTGCGGACCAAATCATGTACACCGGTTTTGCGTATGCGGCACGTTCTGGTTCTTCTGTA
GGTATCGATGACATGGTCATTCCTGCCAAGAAATACGAAATTATTTCTGCAGCAGAAGACGAAGTAGCGGAAATCCAAGA
GCAGTTCCAATCAGGTTTAGTGACAGCGGGCGAACGTTATAACAAAGTGATCGATATTTGGGCGGCAGCAAACGAACGTG
TTGCGAAAGCCATGATGGAAAACCTATCGACTGAAGAAGTGATCAACCGTGAAGGTCAACCAGAGAAACAAGCCTCTTTC
AACAGTATCTTTATGATGGCGGACTCGGGTGCGCGTGGTTCTGCGGCACAGATTCGTCAGTTAGCGGGTATGCGTGGTTT
GATGGCGCGTCCAGATGGTTCGATCATTGAAACACCAATTACCGCAAACTTCCGTGAAGGTCTAAACGTATTACAGTACT
TTATTTCAACCCACGGTGCGCGTAAAGGTCTTGCGGATACGGCATTAAAAACAGCGAACTCCGGTTACTTAACCCGTCGT
TTAGTGGACGTGGCACAAGATTTAGTGATCATCGAAGATGACTGTGGTACACACGAAGGTATCGTGATGACCCCATTAAT
CGAAGGTGGTGATGTGAAAGAAGCACTACGTGATCGTGTATTAGGTCGTGTGGTGGCAGAAGACGTGTTGAAACCAGGCA
CAGAAGAAGTGTTGATTGCACGCAATACCTTATTAGATGAGAAATTGTGTGATGTGATCGACAGTAATTCTGTGGATAGC
ATCAAAGTGCGCTCCGTTGTAACCTGTAACACAGACTTCGGTGTGTGTGCCAAATGTTATGGACGTGATCTTGCACGTGG
TCACTTAATCAACCAAGGTGAAGCCGTGGGTGTTATTGCGGCACAATCTATCGGTGAACCGGGTACACAGTTAACGATGC
GTACGTTCCATATCGGTGGTGCGGCGTCTGCAGCAGCGAAAGAATCCAGTATCCAAGTGAAAAACACGGGTACCTTACGT
TTAGCCAACGTGAAATTTGTCACCAATAACGAAGGTAAGTTAGTGTTAACATCACGTAACACCGAATTAACCATTATTGA
TGCCTTTGGTCGTACAAAAGAGCACTATAAAGTGCCTTACGGTGCGATTTTAAGCAAAGGTGATGGGCAAGAGGTGACAG
CCGGTGAAACCGTAGCAAACTGGGATCCACATACTATGCCAGTGGTGTCTGAGGTAAGTGGTTTTGTGAAATTCATTGAC
CTTATTGACGGTTTAACCGTGACACGTCAAACTGATGAGTTGACTGGTTTATCTTCTATCGTGGTACAAGATGTGGGTGA
ACGTGCGACAGCAGGTAAAGACTTACGTCCAGCTATCAAATTAGTGGATGCGAAAGGTAATGATATCTTAATTCCAGGGA
CAGACGTGGTAGCACAGTACTTCTTACCAGGTAAAGCGATCGTGACCTTAGACGACAATGCGGAAGTTCATATCGGTGAA
CCATTAGCACGTATTCCACAAGAATCGGTAGGAACGAAAGATATTACCGGTGGTCTTCCACGCGTAGCAGACTTATTTGA
AGCACGTAAACCGAAAGAGCCAGCCATTTTGGCGGAAATTTCAGGTATCGTGTCCTTCGGTAAAGAAACCAAAGGTAAAC
GTCGCTTATTGATCACCCCGGCTGAAGGTGAAACTTACGAAGAAATGATTCCAAAATGGCGTCAGCTCAACGTATTTGAA
GGCGAAATGGTGGAGCGTGGTGACTTGATCTCGGATGGTGCAGAAACCCCACATGATATCTTACGCTTACGTGGCGTTCA
CGCAGTCACAGAATATATCGTTAACGAAGTACAAGAAGTTTACCGCTTACAAGGGGTAAAAATTAACGATAAACACATCG
AAGTGATCGTTCGCCAAATGTTACGTAAAGGTATTGTCACGAAAGCTTATGACTCTGAATTCTTAGAGGGTGAGCAAGTC
GAAGTGGCACGCGTGAAAATTGTGAACCGTAAGCGTGAAGCTGAAGGTAAACCATTAGTTGAATTTGAACGTGAATTGCT
TGGTATTACTAAAGCGTCTCTTGCAACTGAGTCATTTATCTCAGCAGCATCGTTCCAAGAAACCACACGTGTGTTAACCG
AAGCCGCAGTGGCAGGTAAACGTGATGAATTACGTGGCTTGAAAGAGAACGTAATTGTGGGTCGTTTAATCCCAGCGGGT
ACCGGTTTTGCTTACCACCAAAATCGTCAGAAGAAAGTGGTGATGAGTGATGAAATGCCAGTGAAATTATCTGCCGCAGA
TGAAGAAGAAATCGCAGCAGAATTTACGGTGACTGCAGAAGACGCCACAGCAAGTTTAGCAGAAATGTTAAATATGGCTG
ATGATGCAGAATAA

Upstream 100 bases:

>100_bases
TAACCAAGCTTGGTGTAAAGCAATGTACGCGCAAGTGCGGTAAAAATTTTTAAAATTTCAGCCGCACTTGAATAAGTTTA
ACTCCGACAGGAGCAAATCT

Downstream 100 bases:

>100_bases
GCCTGATTAAGCAAAAAGCCCGAGCCTTAGGTTCGGGTTTTTTATTCGCTAAATTGTAAAATTCCCTTTATAATGACCGC
ACTTTATTCCATTCCAAACA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1417; Mature: 1417

Protein sequence:

>1417_residues
MKDLVKFLKAQSKTSEDFDVIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLK
HRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYIVIEPGMTDLDKGQL
LTEEQYIDAEDRWGDEFDAKMGAEAIQALLRDMDLPQECENLREELQETNSETKRKKITKRLKLLEAFIQSGNKPEWMVM
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLIAPDIIVRNEKRMLQESVDALLDNGRRGRAITGS
NRRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYAKLESRGFASTIKAAKK
MVEREDAIVWDILADVIREHPILLNRAPTLHRLGIQAFEPLLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
ARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDKVNGKGEGMLLQDPREAEKAYRTGQVELHSRVKVRITEYVKNA
VGEFEPQTNLVDTTIGRAILWMIAPKGMPFSLFNQTLGKKAISKLINESYRRLGMKPSVLFADQIMYTGFAYAARSGSSV
GIDDMVIPAKKYEIISAAEDEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGQPEKQASF
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRR
LVDVAQDLVIIEDDCGTHEGIVMTPLIEGGDVKEALRDRVLGRVVAEDVLKPGTEEVLIARNTLLDEKLCDVIDSNSVDS
IKVRSVVTCNTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNTGTLR
LANVKFVTNNEGKLVLTSRNTELTIIDAFGRTKEHYKVPYGAILSKGDGQEVTAGETVANWDPHTMPVVSEVSGFVKFID
LIDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPAIKLVDAKGNDILIPGTDVVAQYFLPGKAIVTLDDNAEVHIGE
PLARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLLITPAEGETYEEMIPKWRQLNVFE
GEMVERGDLISDGAETPHDILRLRGVHAVTEYIVNEVQEVYRLQGVKINDKHIEVIVRQMLRKGIVTKAYDSEFLEGEQV
EVARVKIVNRKREAEGKPLVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGFAYHQNRQKKVVMSDEMPVKLSAADEEEIAAEFTVTAEDATASLAEMLNMADDAE

Sequences:

>Translated_1417_residues
MKDLVKFLKAQSKTSEDFDVIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLK
HRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYIVIEPGMTDLDKGQL
LTEEQYIDAEDRWGDEFDAKMGAEAIQALLRDMDLPQECENLREELQETNSETKRKKITKRLKLLEAFIQSGNKPEWMVM
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLIAPDIIVRNEKRMLQESVDALLDNGRRGRAITGS
NRRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYAKLESRGFASTIKAAKK
MVEREDAIVWDILADVIREHPILLNRAPTLHRLGIQAFEPLLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
ARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDKVNGKGEGMLLQDPREAEKAYRTGQVELHSRVKVRITEYVKNA
VGEFEPQTNLVDTTIGRAILWMIAPKGMPFSLFNQTLGKKAISKLINESYRRLGMKPSVLFADQIMYTGFAYAARSGSSV
GIDDMVIPAKKYEIISAAEDEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGQPEKQASF
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRR
LVDVAQDLVIIEDDCGTHEGIVMTPLIEGGDVKEALRDRVLGRVVAEDVLKPGTEEVLIARNTLLDEKLCDVIDSNSVDS
IKVRSVVTCNTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNTGTLR
LANVKFVTNNEGKLVLTSRNTELTIIDAFGRTKEHYKVPYGAILSKGDGQEVTAGETVANWDPHTMPVVSEVSGFVKFID
LIDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPAIKLVDAKGNDILIPGTDVVAQYFLPGKAIVTLDDNAEVHIGE
PLARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLLITPAEGETYEEMIPKWRQLNVFE
GEMVERGDLISDGAETPHDILRLRGVHAVTEYIVNEVQEVYRLQGVKINDKHIEVIVRQMLRKGIVTKAYDSEFLEGEQV
EVARVKIVNRKREAEGKPLVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGFAYHQNRQKKVVMSDEMPVKLSAADEEEIAAEFTVTAEDATASLAEMLNMADDAE
>Mature_1417_residues
MKDLVKFLKAQSKTSEDFDVIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLK
HRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYIVIEPGMTDLDKGQL
LTEEQYIDAEDRWGDEFDAKMGAEAIQALLRDMDLPQECENLREELQETNSETKRKKITKRLKLLEAFIQSGNKPEWMVM
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLIAPDIIVRNEKRMLQESVDALLDNGRRGRAITGS
NRRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYAKLESRGFASTIKAAKK
MVEREDAIVWDILADVIREHPILLNRAPTLHRLGIQAFEPLLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
ARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDKVNGKGEGMLLQDPREAEKAYRTGQVELHSRVKVRITEYVKNA
VGEFEPQTNLVDTTIGRAILWMIAPKGMPFSLFNQTLGKKAISKLINESYRRLGMKPSVLFADQIMYTGFAYAARSGSSV
GIDDMVIPAKKYEIISAAEDEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGQPEKQASF
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRR
LVDVAQDLVIIEDDCGTHEGIVMTPLIEGGDVKEALRDRVLGRVVAEDVLKPGTEEVLIARNTLLDEKLCDVIDSNSVDS
IKVRSVVTCNTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNTGTLR
LANVKFVTNNEGKLVLTSRNTELTIIDAFGRTKEHYKVPYGAILSKGDGQEVTAGETVANWDPHTMPVVSEVSGFVKFID
LIDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPAIKLVDAKGNDILIPGTDVVAQYFLPGKAIVTLDDNAEVHIGE
PLARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLLITPAEGETYEEMIPKWRQLNVFE
GEMVERGDLISDGAETPHDILRLRGVHAVTEYIVNEVQEVYRLQGVKINDKHIEVIVRQMLRKGIVTKAYDSEFLEGEQV
EVARVKIVNRKREAEGKPLVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGFAYHQNRQKKVVMSDEMPVKLSAADEEEIAAEFTVTAEDATASLAEMLNMADDAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=929, Percent_Identity=26.5877287405813, Blast_Score=207, Evalue=5e-53,
Organism=Homo sapiens, GI39725938, Length=308, Percent_Identity=29.5454545454545, Blast_Score=128, Evalue=3e-29,
Organism=Homo sapiens, GI103471997, Length=598, Percent_Identity=24.7491638795987, Blast_Score=117, Evalue=9e-26,
Organism=Escherichia coli, GI2367335, Length=1412, Percent_Identity=83.2152974504249, Blast_Score=2424, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=914, Percent_Identity=26.2582056892779, Blast_Score=184, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI25145495, Length=713, Percent_Identity=25.8064516129032, Blast_Score=177, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6320061, Length=545, Percent_Identity=25.8715596330275, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324690, Length=327, Percent_Identity=30.5810397553517, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324917, Length=382, Percent_Identity=25.3926701570681, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17530899, Length=914, Percent_Identity=24.72647702407, Blast_Score=183, Evalue=8e-46,
Organism=Drosophila melanogaster, GI281360912, Length=505, Percent_Identity=25.3465346534653, Blast_Score=130, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 157189; Mature: 157189

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00381 CLP_PROTEASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLVKFLKAQSKTSEDFDVIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCA
CHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
LPSRIGLLLDMPLRDIERVLYFESYIVIEPGMTDLDKGQLLTEEQYIDAEDRWGDEFDAK
HHHHHCEEECCCHHHHHHHHHHHCEEEECCCCCCCCCCCEECHHHCCCCHHCCCCHHHHH
MGAEAIQALLRDMDLPQECENLREELQETNSETKRKKITKRLKLLEAFIQSGNKPEWMVM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLIAPDIIVRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEECCHHHHH
QESVDALLDNGRRGRAITGSNRRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGP
HHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
YLHLHQCGLPKKMALELFRPFIYAKLESRGFASTIKAAKKMVEREDAIVWDILADVIREH
EEEEHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PILLNRAPTLHRLGIQAFEPLLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
CEEECCCCCHHHHCHHHHCCEEECCCEEEECCEEEEEECCCCCCCCEEEEEEEEEECCHH
ARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDKVNGKGEGMLLQDPREAEKAYRT
HHHHEEECCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCEEECCCHHHHHHHHC
GQVELHSRVKVRITEYVKNAVGEFEPQTNLVDTTIGRAILWMIAPKGMPFSLFNQTLGKK
CCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEEEECCCCCCHHHHHHHHHHH
AISKLINESYRRLGMKPSVLFADQIMYTGFAYAARSGSSVGIDDMVIPAKKYEIISAAED
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHCCHH
EVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGQPEKQASF
HHHHHHHHHHCCCCCCCHHHHHEEEEEHHCHHHHHHHHHHCCCHHHHHCCCCCCHHHCCC
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGA
CEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCC
RKGLADTALKTANSGYLTRRLVDVAQDLVIIEDDCGTHEGIVMTPLIEGGDVKEALRDRV
CCCHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHH
LGRVVAEDVLKPGTEEVLIARNTLLDEKLCDVIDSNSVDSIKVRSVVTCNTDFGVCAKCY
HHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHH
GRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNTGTLR
CCHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHCCCCCEEEECCCEEE
LANVKFVTNNEGKLVLTSRNTELTIIDAFGRTKEHYKVPYGAILSKGDGQEVTAGETVAN
EEEEEEEECCCCEEEEEECCCEEEEEECCCCCCHHCCCCHHHHEECCCCCEEECCCEECC
WDPHTMPVVSEVSGFVKFIDLIDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPAIK
CCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCHHCCCCCCCCHHE
LVDAKGNDILIPGTDVVAQYFLPGKAIVTLDDNAEVHIGEPLARIPQESVGTKDITGGLP
EEECCCCEEEECCHHHHHHHHCCCCEEEEECCCCCEEECCHHHHCCHHHCCCCCCCCCCH
RVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLLITPAEGETYEEMIPKWRQLNVFE
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCHHHCCCCCC
GEMVERGDLISDGAETPHDILRLRGVHAVTEYIVNEVQEVYRLQGVKINDKHIEVIVRQM
CCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKGIVTKAYDSEFLEGEQVEVARVKIVNRKREAEGKPLVEFERELLGITKASLATESFI
HHCCCCEECCCHHHCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGFAYHQNRQKKVVMSDEMP
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCCCCCCCCCEEEECCCCC
VKLSAADEEEIAAEFTVTAEDATASLAEMLNMADDAE
EEEECCCCHHHHEEEEEECCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKDLVKFLKAQSKTSEDFDVIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCA
CHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
LPSRIGLLLDMPLRDIERVLYFESYIVIEPGMTDLDKGQLLTEEQYIDAEDRWGDEFDAK
HHHHHCEEECCCHHHHHHHHHHHCEEEECCCCCCCCCCCEECHHHCCCCHHCCCCHHHHH
MGAEAIQALLRDMDLPQECENLREELQETNSETKRKKITKRLKLLEAFIQSGNKPEWMVM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLIAPDIIVRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEECCHHHHH
QESVDALLDNGRRGRAITGSNRRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGP
HHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
YLHLHQCGLPKKMALELFRPFIYAKLESRGFASTIKAAKKMVEREDAIVWDILADVIREH
EEEEHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PILLNRAPTLHRLGIQAFEPLLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
CEEECCCCCHHHHCHHHHCCEEECCCEEEECCEEEEEECCCCCCCCEEEEEEEEEECCHH
ARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDKVNGKGEGMLLQDPREAEKAYRT
HHHHEEECCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCEEECCCHHHHHHHHC
GQVELHSRVKVRITEYVKNAVGEFEPQTNLVDTTIGRAILWMIAPKGMPFSLFNQTLGKK
CCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEEEECCCCCCHHHHHHHHHHH
AISKLINESYRRLGMKPSVLFADQIMYTGFAYAARSGSSVGIDDMVIPAKKYEIISAAED
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHCCHH
EVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGQPEKQASF
HHHHHHHHHHCCCCCCCHHHHHEEEEEHHCHHHHHHHHHHCCCHHHHHCCCCCCHHHCCC
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGA
CEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCC
RKGLADTALKTANSGYLTRRLVDVAQDLVIIEDDCGTHEGIVMTPLIEGGDVKEALRDRV
CCCHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHH
LGRVVAEDVLKPGTEEVLIARNTLLDEKLCDVIDSNSVDSIKVRSVVTCNTDFGVCAKCY
HHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHH
GRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNTGTLR
CCHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHCCCCCEEEECCCEEE
LANVKFVTNNEGKLVLTSRNTELTIIDAFGRTKEHYKVPYGAILSKGDGQEVTAGETVAN
EEEEEEEECCCCEEEEEECCCEEEEEECCCCCCHHCCCCHHHHEECCCCCEEECCCEECC
WDPHTMPVVSEVSGFVKFIDLIDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPAIK
CCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCHHCCCCCCCCHHE
LVDAKGNDILIPGTDVVAQYFLPGKAIVTLDDNAEVHIGEPLARIPQESVGTKDITGGLP
EEECCCCEEEECCHHHHHHHHCCCCEEEEECCCCCEEECCHHHHCCHHHCCCCCCCCCCH
RVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLLITPAEGETYEEMIPKWRQLNVFE
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCHHHCCCCCC
GEMVERGDLISDGAETPHDILRLRGVHAVTEYIVNEVQEVYRLQGVKINDKHIEVIVRQM
CCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKGIVTKAYDSEFLEGEQVEVARVKIVNRKREAEGKPLVEFERELLGITKASLATESFI
HHCCCCEECCCHHHCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGFAYHQNRQKKVVMSDEMP
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCCCCCCCCCEEEECCCCC
VKLSAADEEEIAAEFTVTAEDATASLAEMLNMADDAE
EEEECCCCHHHHEEEEEECCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA