Click here to switch to the map view.

The map label for this gene is nudC

Identifier: 15603600

GI number: 15603600

Start: 1951291

End: 1952085

Strand: Reverse

Name: nudC

Synonym: PM1735

Alternate gene names: 15603600

Gene position: 1952085-1951291 (Counterclockwise)

Preceding gene: 15603601

Following gene: 15603599

Centisome position: 86.47

GC content: 43.77

Gene sequence:

>795_bases
ATGAATGCGATTCAACCTGATGATGCCGGTTATTGGTTATTAACCCAAGATTCAGCCTTATATTTGATTAATGGGGAGCT
ACCTCAAGGTAAGGCGGCTGATTTTCAGTTACAAGGCTATAATGGGATGATAATTGGTGAGCTCAATGGGCGGCCTTTAT
GGTTGGTGGAGGAGATAGCGGACGATCAGCGAACCTATTTCTCTTTACGTAGCTTATTAGCGTTGCCAGAAGCGCATTTT
AATCTGCTTAACCGTGGTGTTGAGCTAAACCATTTCTTTAAAACTCATCGTTTTTGTGGCAAATGTGGACATCCTACTGA
CCTTGTGCAGCAGGAATGGGCGATTCAATGTCAGAATCCATCCTGTTCACACCGCACTTACCCTGTGATTTGTCCTTGTA
TTATTGTCGCGGTACGCCGTGGCGCACAAATTCTATTGGCTAACCACCAACGTCATAAGGGCGGCATTTACACGACTTTA
GCGGGATTTGTTGAAGTAGGTGAAACCTTTGAACAGGCGGTACATCGAGAAGTGTTGGAAGAAACAGGCATTCAGATTCA
GAATTTACGTTATTTCGGGAGCCAACCTTGGGCTTTTCCTAATTCTGCTATGATTGGCTTTTTAGCCGATTATGCAGGAG
GAGAGATTTGTGTACAAGAAATGGAAATTCATGATGCGCAATGGTTTGATTATAATGCGCCCCTCCCAGAGTTACCACCG
AAAGGCACTATCGCGTTAAAATTAATTGAGCATACATTGCAACTGTGTGCTGAGGAAGAAAGGAAAGCAACATGA

Upstream 100 bases:

>100_bases
TATTCGCTAAATTGTAAAATTCCCTTTATAATGACCGCACTTTATTCCATTCCAAACAGCAAAAAGTGCGGTCATTTTTT
GCTATATTTTGTGAGCCTAT

Downstream 100 bases:

>100_bases
CTGCATTAAAAAATGATCGCTATTTAAAAGCATTATTACGTGAGCCTGTCGATATGACACCGGTTTGGATGATGCGTCAA
GCGGGGCGCTATTTACCAGA

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNAIQPDDAGYWLLTQDSALYLINGELPQGKAADFQLQGYNGMIIGELNGRPLWLVEEIADDQRTYFSLRSLLALPEAHF
NLLNRGVELNHFFKTHRFCGKCGHPTDLVQQEWAIQCQNPSCSHRTYPVICPCIIVAVRRGAQILLANHQRHKGGIYTTL
AGFVEVGETFEQAVHREVLEETGIQIQNLRYFGSQPWAFPNSAMIGFLADYAGGEICVQEMEIHDAQWFDYNAPLPELPP
KGTIALKLIEHTLQLCAEEERKAT

Sequences:

>Translated_264_residues
MNAIQPDDAGYWLLTQDSALYLINGELPQGKAADFQLQGYNGMIIGELNGRPLWLVEEIADDQRTYFSLRSLLALPEAHF
NLLNRGVELNHFFKTHRFCGKCGHPTDLVQQEWAIQCQNPSCSHRTYPVICPCIIVAVRRGAQILLANHQRHKGGIYTTL
AGFVEVGETFEQAVHREVLEETGIQIQNLRYFGSQPWAFPNSAMIGFLADYAGGEICVQEMEIHDAQWFDYNAPLPELPP
KGTIALKLIEHTLQLCAEEERKAT
>Mature_264_residues
MNAIQPDDAGYWLLTQDSALYLINGELPQGKAADFQLQGYNGMIIGELNGRPLWLVEEIADDQRTYFSLRSLLALPEAHF
NLLNRGVELNHFFKTHRFCGKCGHPTDLVQQEWAIQCQNPSCSHRTYPVICPCIIVAVRRGAQILLANHQRHKGGIYTTL
AGFVEVGETFEQAVHREVLEETGIQIQNLRYFGSQPWAFPNSAMIGFLADYAGGEICVQEMEIHDAQWFDYNAPLPELPP
KGTIALKLIEHTLQLCAEEERKAT

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI13899267, Length=203, Percent_Identity=33.4975369458128, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI50593112, Length=176, Percent_Identity=34.0909090909091, Blast_Score=98, Evalue=8e-21,
Organism=Escherichia coli, GI48994995, Length=256, Percent_Identity=47.65625, Blast_Score=253, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI212645999, Length=158, Percent_Identity=31.0126582278481, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71986510, Length=158, Percent_Identity=31.0126582278481, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6321371, Length=196, Percent_Identity=32.6530612244898, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUDC_PASMU (P57965)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246674.1
- ProteinModelPortal:   P57965
- SMR:   P57965
- GeneID:   1245082
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1735
- NMPDR:   fig|272843.1.peg.1736
- HOGENOM:   HBG736436
- OMA:   WLAFSSA
- ProtClustDB:   PRK00241
- BioCyc:   PMUL272843:PM1735-MONOMER
- BRENDA:   3.6.1.22
- HAMAP:   MF_00297
- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376
- Gene3D:   G3DSA:3.90.79.10

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase; SSF55811 NUDIX_hydrolase

EC number: =3.6.1.22

Molecular weight: Translated: 29767; Mature: 29767

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAIQPDDAGYWLLTQDSALYLINGELPQGKAADFQLQGYNGMIIGELNGRPLWLVEEIA
CCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCEEEECCCEEEEECCCCCEEEEEHHHC
DDQRTYFSLRSLLALPEAHFNLLNRGVELNHFFKTHRFCGKCGHPTDLVQQEWAIQCQNP
CHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHEEEECCC
SCSHRTYPVICPCIIVAVRRGAQILLANHQRHKGGIYTTLAGFVEVGETFEQAVHREVLE
CCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETGIQIQNLRYFGSQPWAFPNSAMIGFLADYAGGEICVQEMEIHDAQWFDYNAPLPELPP
HHCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHCCCEEEECCCCCCCCCC
KGTIALKLIEHTLQLCAEEERKAT
CCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAIQPDDAGYWLLTQDSALYLINGELPQGKAADFQLQGYNGMIIGELNGRPLWLVEEIA
CCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCEEEECCCEEEEECCCCCEEEEEHHHC
DDQRTYFSLRSLLALPEAHFNLLNRGVELNHFFKTHRFCGKCGHPTDLVQQEWAIQCQNP
CHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHEEEECCC
SCSHRTYPVICPCIIVAVRRGAQILLANHQRHKGGIYTTLAGFVEVGETFEQAVHREVLE
CCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETGIQIQNLRYFGSQPWAFPNSAMIGFLADYAGGEICVQEMEIHDAQWFDYNAPLPELPP
HHCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHCCCEEEECCCCCCCCCC
KGTIALKLIEHTLQLCAEEERKAT
CCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100