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The map label for this gene is nanE

Identifier: 15603576

GI number: 15603576

Start: 1919956

End: 1920642

Strand: Direct

Name: nanE

Synonym: PM1711

Alternate gene names: 15603576

Gene position: 1919956-1920642 (Clockwise)

Preceding gene: 15603575

Following gene: 15603577

Centisome position: 85.05

GC content: 45.71

Gene sequence:

>687_bases
ATGTCAAAACTATCACATCCGCAAGTTTTAGAACAAATTAAATATGGCTTAATCGCATCTTGCCAGCCCGTAGATAATGG
GCCAATGGACTCGCCAGAAATTGTTGCCGCCATGGCGCAAGCATCCGTTATCGGTGGTGCTGCCGGGTTACGTATTGAAG
GGATCGAAAATTTAAAAGCCACGCGTAACGTCGTCAATGTACCGATTATTGGTATCGTTAAACGCGATTTACCTGACAGT
CCCGTTCGTATTAGCCCATTTTTACAAGACATTGAAGAGTTAGCCGCAGCAGGCGCCGATATTATTGCTTTTGATGGTAC
CGATCGCGTCCGTCCAACCACACGTGAAGCCATTATTAAACGAATCAAAGAATTAGGTTGTTTAGCCATGGCGGATTGTT
CTAATTTTGAAGAAGGGATGTATTGCCACAACTTAGGGGTAGAAATTATTGGTAGCACCATGTCTGGTTATACTGGCGGT
GAAATTCCAGCTGAACCGGACTATCAGTTAGTCAAAGATTTGAATGCTGCTGGCTGCCGAGTGATGGCAGAAGGGCGCTA
TAACACCCCAGAATTGGCGAAAACCGCAATTGAGATTGGTGCTTACTCTGTCACCGTAGGATCTGCGCTGACTCGCCTAG
AACATATCGTAAGCTGGTTTGCCGATGCCGTCAAATCGGCAAAATAA

Upstream 100 bases:

>100_bases
TCTCAAATTTTTATTATTTTGGTTGTTATTTTTTAATTCTAAGATTAATCTATGCAAATTGGAGTCAATCTTCTTTTGAT
AAATTTAGACTGGAGTTAAT

Downstream 100 bases:

>100_bases
GTCATCACAGAAGGAGAGCCTATGCGCTGTTTAGCATTAGATATTGGTGGAACAAAAATTGCCTCGGCTATTGTAACAGA
CGGCAAAATAGAACAACGCC

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSKLSHPQVLEQIKYGLIASCQPVDNGPMDSPEIVAAMAQASVIGGAAGLRIEGIENLKATRNVVNVPIIGIVKRDLPDS
PVRISPFLQDIEELAAAGADIIAFDGTDRVRPTTREAIIKRIKELGCLAMADCSNFEEGMYCHNLGVEIIGSTMSGYTGG
EIPAEPDYQLVKDLNAAGCRVMAEGRYNTPELAKTAIEIGAYSVTVGSALTRLEHIVSWFADAVKSAK

Sequences:

>Translated_228_residues
MSKLSHPQVLEQIKYGLIASCQPVDNGPMDSPEIVAAMAQASVIGGAAGLRIEGIENLKATRNVVNVPIIGIVKRDLPDS
PVRISPFLQDIEELAAAGADIIAFDGTDRVRPTTREAIIKRIKELGCLAMADCSNFEEGMYCHNLGVEIIGSTMSGYTGG
EIPAEPDYQLVKDLNAAGCRVMAEGRYNTPELAKTAIEIGAYSVTVGSALTRLEHIVSWFADAVKSAK
>Mature_227_residues
SKLSHPQVLEQIKYGLIASCQPVDNGPMDSPEIVAAMAQASVIGGAAGLRIEGIENLKATRNVVNVPIIGIVKRDLPDSP
VRISPFLQDIEELAAAGADIIAFDGTDRVRPTTREAIIKRIKELGCLAMADCSNFEEGMYCHNLGVEIIGSTMSGYTGGE
IPAEPDYQLVKDLNAAGCRVMAEGRYNTPELAKTAIEIGAYSVTVGSALTRLEHIVSWFADAVKSAK

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family

Homologues:

Organism=Escherichia coli, GI1789617, Length=212, Percent_Identity=62.2641509433962, Blast_Score=260, Evalue=6e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NANE_PASMU (Q9L6B4)

Other databases:

- EMBL:   AF237924
- EMBL:   AE004439
- RefSeq:   NP_246650.1
- ProteinModelPortal:   Q9L6B4
- SMR:   Q9L6B4
- PRIDE:   Q9L6B4
- GeneID:   1245058
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1711
- NMPDR:   fig|272843.1.peg.1712
- HOGENOM:   HBG296941
- OMA:   EHIVSWF
- ProtClustDB:   PRK01130
- BioCyc:   PMUL272843:PM1711-MONOMER
- BRENDA:   5.1.3.9
- HAMAP:   MF_01235
- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF04131 NanE; SSF51366 RibP_bind_barrel

EC number: =5.1.3.9

Molecular weight: Translated: 24316; Mature: 24185

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLSHPQVLEQIKYGLIASCQPVDNGPMDSPEIVAAMAQASVIGGAAGLRIEGIENLKA
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHH
TRNVVNVPIIGIVKRDLPDSPVRISPFLQDIEELAAAGADIIAFDGTDRVRPTTREAIIK
HHHHHCCCEEEEEECCCCCCCCEECHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHH
RIKELGCLAMADCSNFEEGMYCHNLGVEIIGSTMSGYTGGEIPAEPDYQLVKDLNAAGCR
HHHHHCCCHHHCCCCCCCCCEEHHCCHHHCCCHHCCCCCCCCCCCCCHHHHHCCCCCCCE
VMAEGRYNTPELAKTAIEIGAYSVTVGSALTRLEHIVSWFADAVKSAK
EEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKLSHPQVLEQIKYGLIASCQPVDNGPMDSPEIVAAMAQASVIGGAAGLRIEGIENLKA
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHH
TRNVVNVPIIGIVKRDLPDSPVRISPFLQDIEELAAAGADIIAFDGTDRVRPTTREAIIK
HHHHHCCCEEEEEECCCCCCCCEECHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHH
RIKELGCLAMADCSNFEEGMYCHNLGVEIIGSTMSGYTGGEIPAEPDYQLVKDLNAAGCR
HHHHHCCCHHHCCCCCCCCCEEHHCCHHHCCCHHCCCCCCCCCCCCCHHHHHCCCCCCCE
VMAEGRYNTPELAKTAIEIGAYSVTVGSALTRLEHIVSWFADAVKSAK
EEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10873488; 11248100