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The map label for this gene is ycfH [C]

Identifier: 15603540

GI number: 15603540

Start: 1882042

End: 1882824

Strand: Direct

Name: ycfH [C]

Synonym: PM1675

Alternate gene names: 15603540

Gene position: 1882042-1882824 (Clockwise)

Preceding gene: 15603539

Following gene: 15603541

Centisome position: 83.37

GC content: 40.61

Gene sequence:

>783_bases
ATGTTTATTGTCGATTCCCACTGTCATCTTGATGCACTGGATTATGAAAACTTACACAGCAGTGTTGATGACGTGGTTAA
CAAAGCCATGGAAAGAGAAGTGAAACATTTACTTGCTGTAGGGGTTACCTTAACTCGTTTTGAGCAAATTTATGCCACAT
TGGCTAAATTTAAGAATGTTTCTTTAGCATGTGGTGTACACCCCCTCGATCTGGATGATGAGCCGTTTGATGCCGATCGT
CTGTTGAAATTAGCAGATGATCCCAAAGTTGTCGCGATTGGTGAAACCGGATTAGATTACTATTACAGCGCAGAAAATAA
AACAACCCAACAGGCGATTTTTGCCAACCAAATTCAAATTGCTAACCAATTGAATAAACCGGTAATTGTGCATACTCGCA
GTGCCCGAGAAGATACCATTCGTTTGCTGGCTGAAAATCATGCGGATAAGTGCGGTGGCGTATTACATTGTTTTACTGAA
AATTGGGACATGGCGAAAAAGGGCTTAGATTTAGGACTGTATATTTCGCTGTCGGGTATCATCACGTTTAAAAATGCAGA
AGAAATTCGTGATGTGGCACGTCGTGTACCTCTTGACCGTTTATTAATCGAAACAGATTCCCCTTATTTAGCGCCAGTCC
CTTATCGTGGCAAACAAAATCAACCTGCTTATGTACGCGAAGTCTGTGAGTATGTGGCGACATTAAAAGGCGTGTCTTTT
GAAGAGTTTGCCCAACTCACTACACAAAACTTTGAACGTTTGTTCAAAATTAATGTACAATAA

Upstream 100 bases:

>100_bases
AGTACGTACCGATTTAACGCAAATTAATGCCGTCAACCAAGAACTCATCTTATTAGACGGTCTCACTCAATTAATTACCG
ATGTATTTAAAGGATAAAAT

Downstream 100 bases:

>100_bases
ATCAACTATATACTGGGTGGATAATACTTATTAAGGGAAATACGATGCGAAAATTTTTTAAATACTTTTTTCTGACGGTG
ATTTTTGTTTTTCACCTCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MFIVDSHCHLDALDYENLHSSVDDVVNKAMEREVKHLLAVGVTLTRFEQIYATLAKFKNVSLACGVHPLDLDDEPFDADR
LLKLADDPKVVAIGETGLDYYYSAENKTTQQAIFANQIQIANQLNKPVIVHTRSAREDTIRLLAENHADKCGGVLHCFTE
NWDMAKKGLDLGLYISLSGIITFKNAEEIRDVARRVPLDRLLIETDSPYLAPVPYRGKQNQPAYVREVCEYVATLKGVSF
EEFAQLTTQNFERLFKINVQ

Sequences:

>Translated_260_residues
MFIVDSHCHLDALDYENLHSSVDDVVNKAMEREVKHLLAVGVTLTRFEQIYATLAKFKNVSLACGVHPLDLDDEPFDADR
LLKLADDPKVVAIGETGLDYYYSAENKTTQQAIFANQIQIANQLNKPVIVHTRSAREDTIRLLAENHADKCGGVLHCFTE
NWDMAKKGLDLGLYISLSGIITFKNAEEIRDVARRVPLDRLLIETDSPYLAPVPYRGKQNQPAYVREVCEYVATLKGVSF
EEFAQLTTQNFERLFKINVQ
>Mature_260_residues
MFIVDSHCHLDALDYENLHSSVDDVVNKAMEREVKHLLAVGVTLTRFEQIYATLAKFKNVSLACGVHPLDLDDEPFDADR
LLKLADDPKVVAIGETGLDYYYSAENKTTQQAIFANQIQIANQLNKPVIVHTRSAREDTIRLLAENHADKCGGVLHCFTE
NWDMAKKGLDLGLYISLSGIITFKNAEEIRDVARRVPLDRLLIETDSPYLAPVPYRGKQNQPAYVREVCEYVATLKGVSF
EEFAQLTTQNFERLFKINVQ

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=34.5724907063197, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=34.5724907063197, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=33.9416058394161, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=34.1085271317829, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI225903424, Length=221, Percent_Identity=28.9592760180996, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI14042943, Length=200, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI225903439, Length=135, Percent_Identity=34.8148148148148, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=61.2403100775194, Blast_Score=327, Evalue=6e-91,
Organism=Escherichia coli, GI48994985, Length=242, Percent_Identity=33.8842975206612, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=27.1317829457364, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=273, Percent_Identity=27.8388278388278, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=29.811320754717, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17543026, Length=194, Percent_Identity=28.3505154639175, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=305, Percent_Identity=22.9508196721311, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648690, Length=273, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI221330018, Length=271, Percent_Identity=27.3062730627306, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24586117, Length=271, Percent_Identity=27.3062730627306, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29403; Mature: 29403

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIVDSHCHLDALDYENLHSSVDDVVNKAMEREVKHLLAVGVTLTRFEQIYATLAKFKNV
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLACGVHPLDLDDEPFDADRLLKLADDPKVVAIGETGLDYYYSAENKTTQQAIFANQIQI
EEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHH
ANQLNKPVIVHTRSAREDTIRLLAENHADKCGGVLHCFTENWDMAKKGLDLGLYISLSGI
HHHCCCCEEEEECCCHHHHHHHHHHHCCHHHCCEEEEECCCHHHHHHCCCEEEEEEEEEE
ITFKNAEEIRDVARRVPLDRLLIETDSPYLAPVPYRGKQNQPAYVREVCEYVATLKGVSF
EEECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
EEFAQLTTQNFERLFKINVQ
HHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MFIVDSHCHLDALDYENLHSSVDDVVNKAMEREVKHLLAVGVTLTRFEQIYATLAKFKNV
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLACGVHPLDLDDEPFDADRLLKLADDPKVVAIGETGLDYYYSAENKTTQQAIFANQIQI
EEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHH
ANQLNKPVIVHTRSAREDTIRLLAENHADKCGGVLHCFTENWDMAKKGLDLGLYISLSGI
HHHCCCCEEEEECCCHHHHHHHHHHHCCHHHCCEEEEECCCHHHHHHCCCEEEEEEEEEE
ITFKNAEEIRDVARRVPLDRLLIETDSPYLAPVPYRGKQNQPAYVREVCEYVATLKGVSF
EEECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
EEFAQLTTQNFERLFKINVQ
HHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]