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The map label for this gene is tal_2

Identifier: 15603504

GI number: 15603504

Start: 1848716

End: 1849666

Strand: Reverse

Name: tal_2

Synonym: PM1639

Alternate gene names: 15603504

Gene position: 1849666-1848716 (Counterclockwise)

Preceding gene: 15603505

Following gene: 15603503

Centisome position: 81.93

GC content: 39.43

Gene sequence:

>951_bases
ATGACACAATTAGATTCGTTACGCAGTATGACGGTTGTTGTCGCAGATACTGGTGATATTGAAGCAATTAAGCAATATCA
GCCACAAGATGCAACAACAAATCCTTCTTTGATTTTAAGTGCTTCTGCATTGCCCCAGTATGCGCCATTAATTGATGACG
CCATTGCTTATGCGAAAACAAAAAGTGATTGTCCACGCCAGCAATTGGTTGATGCTGAAGATAAACTGGCCGTTAATATC
GGCTTAGAAATACTCAAAATTATCCCCGGACGGATTTCTACAGAAGTCGATGCAAGGCTTTCGTATGATACACAAGCGAC
TATTGAGAAAGCGCGTAAATTGATCAAGCTTTATAATGAAGCGGGAATAGAGAATCATCGGATCCTCATCAAAATTGCTT
CAACTTGGCAAGGTATTCGTGCTGCAGAAGTGCTTGAGAAAGAAGGAATTAATTGTAACTTGACGTTGTTGTTTTCTGAA
GCACAAGCGAGAGCTTGTGCTGAAGCCGGTGTGTATTTAATTTCACCGTTTGTAGGGCGAATTTTAGATTGGCATAAAGC
AAATACGGGTAGACAAGATTATCCGGCTGCGGAAGATCCAGGTGTGATTTCCGTGACTCAAATTTATAATTATTATAAAC
AACATAATTATAAGACGGTTGTCATGGGCGCAAGTTTCCGAAATGTAGATGAAATTATTGAGTTAGCAGGATGTGATCGT
TTGACGATTTCACCTACTTTATTGAGTCATTTACAAGCAAGAGAAGGGGAACTTGTTCGTAAGTTAGCATTCAGCGGCGA
GTTAAAAGACAGACCTCAACCTTTAACAGAGAGCGAGTTTTATTGGCAACATAACAGCGATCCAATGGCTGTTGCAAAAT
TAGCAGAAGGCATTTGTAAATTTGCAGAAGATCAAGAAAAACTAGAAAAAATGCTCTTGGAAAGACTATAA

Upstream 100 bases:

>100_bases
CTAATCAATATCAAATTATTGTAGGTCCTAAATGGGTAGAAAAAATTTATAGCGAAATGAAAGCGTTATTAGAAACAGAA
TAGATGATAGGGAGAAGAGC

Downstream 100 bases:

>100_bases
CATGTTGAATAAGAGGGAGTAATCACTATGGCAACACGTAGAGAACTGGCCAATGCCATTCGTTTTTTAAGTATGGATGC
AGTGCAAAAAGCAAAATCAG

Product: transaldolase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTQLDSLRSMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYAPLIDDAIAYAKTKSDCPRQQLVDAEDKLAVNI
GLEILKIIPGRISTEVDARLSYDTQATIEKARKLIKLYNEAGIENHRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSE
AQARACAEAGVYLISPFVGRILDWHKANTGRQDYPAAEDPGVISVTQIYNYYKQHNYKTVVMGASFRNVDEIIELAGCDR
LTISPTLLSHLQAREGELVRKLAFSGELKDRPQPLTESEFYWQHNSDPMAVAKLAEGICKFAEDQEKLEKMLLERL

Sequences:

>Translated_316_residues
MTQLDSLRSMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYAPLIDDAIAYAKTKSDCPRQQLVDAEDKLAVNI
GLEILKIIPGRISTEVDARLSYDTQATIEKARKLIKLYNEAGIENHRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSE
AQARACAEAGVYLISPFVGRILDWHKANTGRQDYPAAEDPGVISVTQIYNYYKQHNYKTVVMGASFRNVDEIIELAGCDR
LTISPTLLSHLQAREGELVRKLAFSGELKDRPQPLTESEFYWQHNSDPMAVAKLAEGICKFAEDQEKLEKMLLERL
>Mature_315_residues
TQLDSLRSMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYAPLIDDAIAYAKTKSDCPRQQLVDAEDKLAVNIG
LEILKIIPGRISTEVDARLSYDTQATIEKARKLIKLYNEAGIENHRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSEA
QARACAEAGVYLISPFVGRILDWHKANTGRQDYPAAEDPGVISVTQIYNYYKQHNYKTVVMGASFRNVDEIIELAGCDRL
TISPTLLSHLQAREGELVRKLAFSGELKDRPQPLTESEFYWQHNSDPMAVAKLAEGICKFAEDQEKLEKMLLERL

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=318, Percent_Identity=59.4339622641509, Blast_Score=367, Evalue=1e-101,
Organism=Escherichia coli, GI1786189, Length=310, Percent_Identity=74.1935483870968, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1788807, Length=316, Percent_Identity=62.6582278481013, Blast_Score=410, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI25153750, Length=316, Percent_Identity=57.2784810126582, Blast_Score=346, Evalue=8e-96,
Organism=Caenorhabditis elegans, GI25153752, Length=162, Percent_Identity=54.320987654321, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17570473, Length=94, Percent_Identity=47.8723404255319, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323386, Length=301, Percent_Identity=59.1362126245847, Blast_Score=316, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6321480, Length=323, Percent_Identity=50.7739938080495, Blast_Score=315, Evalue=7e-87,
Organism=Drosophila melanogaster, GI45549185, Length=315, Percent_Identity=59.0476190476191, Blast_Score=368, Evalue=1e-102,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): TALB_PASMU (Q9CKH9)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246578.1
- ProteinModelPortal:   Q9CKH9
- SMR:   Q9CKH9
- PRIDE:   Q9CKH9
- GeneID:   1244986
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1639
- NMPDR:   fig|272843.1.peg.1640
- HOGENOM:   HBG286747
- OMA:   DWHKAKT
- ProtClustDB:   PRK05269
- BioCyc:   PMUL272843:PM1639-MONOMER
- BRENDA:   2.2.1.2
- GO:   GO:0005737
- HAMAP:   MF_00492
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- PANTHER:   PTHR10683:SF3
- TIGRFAMs:   TIGR00874

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 35255; Mature: 35123

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLDSLRSMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYAPLIDDAIAYAKT
CCCHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHC
KSDCPRQQLVDAEDKLAVNIGLEILKIIPGRISTEVDARLSYDTQATIEKARKLIKLYNE
CCCCCHHHHCCCCHHEEEHHHHHHHHHCCCCCCCCHHCEECCCHHHHHHHHHHHHHHHHH
AGIENHRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSEAQARACAEAGVYLISPFVGR
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHH
ILDWHKANTGRQDYPAAEDPGVISVTQIYNYYKQHNYKTVVMGASFRNVDEIIELAGCDR
HHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCC
LTISPTLLSHLQAREGELVRKLAFSGELKDRPQPLTESEFYWQHNSDPMAVAKLAEGICK
EEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHH
FAEDQEKLEKMLLERL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQLDSLRSMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYAPLIDDAIAYAKT
CCHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHC
KSDCPRQQLVDAEDKLAVNIGLEILKIIPGRISTEVDARLSYDTQATIEKARKLIKLYNE
CCCCCHHHHCCCCHHEEEHHHHHHHHHCCCCCCCCHHCEECCCHHHHHHHHHHHHHHHHH
AGIENHRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSEAQARACAEAGVYLISPFVGR
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHH
ILDWHKANTGRQDYPAAEDPGVISVTQIYNYYKQHNYKTVVMGASFRNVDEIIELAGCDR
HHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCC
LTISPTLLSHLQAREGELVRKLAFSGELKDRPQPLTESEFYWQHNSDPMAVAKLAEGICK
EEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHH
FAEDQEKLEKMLLERL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100