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The map label for this gene is surE

Identifier: 15603477

GI number: 15603477

Start: 1821989

End: 1822729

Strand: Direct

Name: surE

Synonym: PM1612

Alternate gene names: 15603477

Gene position: 1821989-1822729 (Clockwise)

Preceding gene: 15603476

Following gene: 15603478

Centisome position: 80.71

GC content: 46.56

Gene sequence:

>741_bases
ATGAAAATTCTTCTCAGCAACGACGATGGGATTCACGCTGAAGGCATTCAAATACTGGCTCGTGAGTTACGTAAATTTGC
TGATGTCACACTTGTCGCCCCTGACCGCAATCGCAGTGCAGCGTCCAGTTCTTTAACATTAGTTGAACCATTACGTCCCT
TACGCTTGCCGAATGGGGATTATTGCCTCAATGGCACCCCCGCCGACTGTGTCTATCTAGCGTTAAATGGGTTTTTATCT
GGACAAGTGGATTTGGTGGTGTCGGGGATCAATGCGGGCGTGAATTTGGGGGATGATGTGATTTATTCAGGTACCGTCGC
TGCGGCATTAGAAGGGCGTTATTTAGGGCTGCCTGCGATTGCGGTTTCTCTTGATGGACGCCAACATTATGAGAGCGCGG
CGCGTGTGGTTTGTGAGTTAATTCCTCGATTGCATGGACAAATTTTACAACGGCGTGAAATTCTCAATATTAATGTCCCG
GATATTCCTTATGAAGAGATTAAAGGAGTGAAAGTGTGTCATTTAGGTTATCGTGCAGCTGCCGCAGAGGTGGTGAAGCA
ACAAGATCCACGAGGTGAGGCGATTTATTGGGTTGGACCGGCGGGCTTAGCGGAAAATGAACAAGAAGGCACAGACTTTC
ATGCAGTGAAAAATGGCTATGTCGCGATTACGCCAATTCAAGCAGATATGACCGCCTATCATTCATTGCAATCTTTACAA
GATTGGTTAGAAAGTGAATAA

Upstream 100 bases:

>100_bases
GTTTGCCAGAAGGGTGTGATTGGGAGTAAAACGTTTCTAAAAAGCACCGCACTTTAAACAAACGCATTCAAAGCATATAA
CAAAGAATAAGGACAACATC

Downstream 100 bases:

>100_bases
TAATCCGTTTTTTATTCTTTATGATGAGGAAGGTGCGCGTTGAAAATTTTTGGTGCGATGTATGATAAAACGATGGCTTG
GTCAAAGCATCGTTATGCCA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKILLSNDDGIHAEGIQILARELRKFADVTLVAPDRNRSAASSSLTLVEPLRPLRLPNGDYCLNGTPADCVYLALNGFLS
GQVDLVVSGINAGVNLGDDVIYSGTVAAALEGRYLGLPAIAVSLDGRQHYESAARVVCELIPRLHGQILQRREILNINVP
DIPYEEIKGVKVCHLGYRAAAAEVVKQQDPRGEAIYWVGPAGLAENEQEGTDFHAVKNGYVAITPIQADMTAYHSLQSLQ
DWLESE

Sequences:

>Translated_246_residues
MKILLSNDDGIHAEGIQILARELRKFADVTLVAPDRNRSAASSSLTLVEPLRPLRLPNGDYCLNGTPADCVYLALNGFLS
GQVDLVVSGINAGVNLGDDVIYSGTVAAALEGRYLGLPAIAVSLDGRQHYESAARVVCELIPRLHGQILQRREILNINVP
DIPYEEIKGVKVCHLGYRAAAAEVVKQQDPRGEAIYWVGPAGLAENEQEGTDFHAVKNGYVAITPIQADMTAYHSLQSLQ
DWLESE
>Mature_246_residues
MKILLSNDDGIHAEGIQILARELRKFADVTLVAPDRNRSAASSSLTLVEPLRPLRLPNGDYCLNGTPADCVYLALNGFLS
GQVDLVVSGINAGVNLGDDVIYSGTVAAALEGRYLGLPAIAVSLDGRQHYESAARVVCELIPRLHGQILQRREILNINVP
DIPYEEIKGVKVCHLGYRAAAAEVVKQQDPRGEAIYWVGPAGLAENEQEGTDFHAVKNGYVAITPIQADMTAYHSLQSLQ
DWLESE

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=246, Percent_Identity=57.7235772357724, Blast_Score=291, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_PASMU (P57955)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246551.1
- ProteinModelPortal:   P57955
- SMR:   P57955
- GeneID:   1244959
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1612
- NMPDR:   fig|272843.1.peg.1613
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- BioCyc:   PMUL272843:PM1612-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 26671; Mature: 26671

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLSNDDGIHAEGIQILARELRKFADVTLVAPDRNRSAASSSLTLVEPLRPLRLPNGD
CEEEEECCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCC
YCLNGTPADCVYLALNGFLSGQVDLVVSGINAGVNLGDDVIYSGTVAAALEGRYLGLPAI
EEECCCCHHHEEEEHHCCCCCCEEEEEECCCCCCCCCCCEEECCEEEEHCCCCEECCCEE
AVSLDGRQHYESAARVVCELIPRLHGQILQRREILNINVPDIPYEEIKGVKVCHLGYRAA
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHCCEEEEECCHHHH
AAEVVKQQDPRGEAIYWVGPAGLAENEQEGTDFHAVKNGYVAITPIQADMTAYHSLQSLQ
HHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCEEEEEECHHHHHHHHHHHHHH
DWLESE
HHHCCC
>Mature Secondary Structure
MKILLSNDDGIHAEGIQILARELRKFADVTLVAPDRNRSAASSSLTLVEPLRPLRLPNGD
CEEEEECCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCC
YCLNGTPADCVYLALNGFLSGQVDLVVSGINAGVNLGDDVIYSGTVAAALEGRYLGLPAI
EEECCCCHHHEEEEHHCCCCCCEEEEEECCCCCCCCCCCEEECCEEEEHCCCCEECCCEE
AVSLDGRQHYESAARVVCELIPRLHGQILQRREILNINVPDIPYEEIKGVKVCHLGYRAA
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHCCEEEEECCHHHH
AAEVVKQQDPRGEAIYWVGPAGLAENEQEGTDFHAVKNGYVAITPIQADMTAYHSLQSLQ
HHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCEEEEEECHHHHHHHHHHHHHH
DWLESE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100