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The map label for this gene is tal_1

Identifier: 15603467

GI number: 15603467

Start: 1814108

End: 1815061

Strand: Direct

Name: tal_1

Synonym: PM1602

Alternate gene names: 15603467

Gene position: 1814108-1815061 (Clockwise)

Preceding gene: 15603464

Following gene: 15603471

Centisome position: 80.36

GC content: 41.3

Gene sequence:

>954_bases
ATGACAACACAACTTGATTCTCTACGTAATATGACGGTGGTGGTTGCTGATACTGGTGATATTGAAGCTATCAAAAAATA
CCAACCTGAAGATGCAACAACGAACCCATCTTTAATTCTCAGCGCGTCTGCCTTGCCACAATATGCCTCATTAATTGATG
AAGCCATTGCTTATGCCAAATCAAAAAGCAACTGTTCAAAACAACAATTAATTGATGCAGAAGATAAATTAGCCGTTAAC
ATCGGCTTGGAAATCTTGAAAATTGTGCCGGGACGCATTTCAACAGAAGTGGATGCTCGTCTTTCTTATGATACACAAGC
AACAATCGAAAAAGCGAAAAAATTAATCGCACTTTATAACGAAGCTGGTATCTCAAACGATCGTATCTTGATCAAAATTG
CTTCAACTTGGCAAGGGATTCGTGCGGCAGAAGAATTAGAAAAACAAGGTATTAACTGTAACTTAACCCTTTTATTCTCT
GAAGCGCAAGCGCGTGCTTGTGCGGAAGCCGGGGTTTACTTAATTTCGCCATTCGTGGGTCGAATTCTTGACTGGTACAA
AGCCAACAGCGATAAAAAAGACTATGCGCCGGCAGAAGATCCGGGTGTGATTTCCGTGACTAAAATCTATAACTATTACA
AACAACACGGCTATAACACGATCGTCATGGGCGCAAGTTTCCGTAATGTCGGTGAAATTACCGAATTAGCCGGCTGTGAC
CGCTTAACCATTGCACCAGCCTTGTTGAAAGAGTTACAAGAAAACAACGCACCACTTGAGCGTAAATTAAGCTACACGGG
CGAAGTGAAAGCAAAACCACAACCATTAACTGAAGCAGAATTCTATTGGCAACACAATAGCGATGCAATGGCAGTGGAAA
AACTGGCTGACGGTATCCGTAAATTTGCGGCCGACCAAGAAAAATTAGAAGCGATGTTATTAACAAAATTCTAA

Upstream 100 bases:

>100_bases
TTAGCAACAGTGCAAGAAAAGATCATTCCATTTTCCTTTTGATATGCTATTGTATATAAGTTCACAACGAAGACATTGTA
ATTCAAAATAGAGGGAAATT

Downstream 100 bases:

>100_bases
TTTTACGTTGAACAAATAGAAAAAGTGCGGTCAATTTTGACCGCATTTTTTATTGCCAAGTTGGTCCAAGTTTTCTTATT
TATCTGGATTGAAGGAACAA

Product: transaldolase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTTQLDSLRNMTVVVADTGDIEAIKKYQPEDATTNPSLILSASALPQYASLIDEAIAYAKSKSNCSKQQLIDAEDKLAVN
IGLEILKIVPGRISTEVDARLSYDTQATIEKAKKLIALYNEAGISNDRILIKIASTWQGIRAAEELEKQGINCNLTLLFS
EAQARACAEAGVYLISPFVGRILDWYKANSDKKDYAPAEDPGVISVTKIYNYYKQHGYNTIVMGASFRNVGEITELAGCD
RLTIAPALLKELQENNAPLERKLSYTGEVKAKPQPLTEAEFYWQHNSDAMAVEKLADGIRKFAADQEKLEAMLLTKF

Sequences:

>Translated_317_residues
MTTQLDSLRNMTVVVADTGDIEAIKKYQPEDATTNPSLILSASALPQYASLIDEAIAYAKSKSNCSKQQLIDAEDKLAVN
IGLEILKIVPGRISTEVDARLSYDTQATIEKAKKLIALYNEAGISNDRILIKIASTWQGIRAAEELEKQGINCNLTLLFS
EAQARACAEAGVYLISPFVGRILDWYKANSDKKDYAPAEDPGVISVTKIYNYYKQHGYNTIVMGASFRNVGEITELAGCD
RLTIAPALLKELQENNAPLERKLSYTGEVKAKPQPLTEAEFYWQHNSDAMAVEKLADGIRKFAADQEKLEAMLLTKF
>Mature_316_residues
TTQLDSLRNMTVVVADTGDIEAIKKYQPEDATTNPSLILSASALPQYASLIDEAIAYAKSKSNCSKQQLIDAEDKLAVNI
GLEILKIVPGRISTEVDARLSYDTQATIEKAKKLIALYNEAGISNDRILIKIASTWQGIRAAEELEKQGINCNLTLLFSE
AQARACAEAGVYLISPFVGRILDWYKANSDKKDYAPAEDPGVISVTKIYNYYKQHGYNTIVMGASFRNVGEITELAGCDR
LTIAPALLKELQENNAPLERKLSYTGEVKAKPQPLTEAEFYWQHNSDAMAVEKLADGIRKFAADQEKLEAMLLTKF

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=316, Percent_Identity=62.6582278481013, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI1786189, Length=313, Percent_Identity=77.6357827476038, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1788807, Length=314, Percent_Identity=64.0127388535032, Blast_Score=421, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI25153750, Length=315, Percent_Identity=57.4603174603175, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25153752, Length=164, Percent_Identity=53.0487804878049, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17570473, Length=96, Percent_Identity=46.875, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321480, Length=314, Percent_Identity=54.7770700636943, Blast_Score=335, Evalue=4e-93,
Organism=Saccharomyces cerevisiae, GI6323386, Length=299, Percent_Identity=60.8695652173913, Blast_Score=330, Evalue=2e-91,
Organism=Drosophila melanogaster, GI45549185, Length=317, Percent_Identity=59.9369085173502, Blast_Score=377, Evalue=1e-105,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): TALA_PASMU (Q9CKL0)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246541.1
- ProteinModelPortal:   Q9CKL0
- SMR:   Q9CKL0
- PRIDE:   Q9CKL0
- GeneID:   1244949
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1602
- NMPDR:   fig|272843.1.peg.1603
- HOGENOM:   HBG286747
- OMA:   KSSGTDY
- ProtClustDB:   PRK05269
- BioCyc:   PMUL272843:PM1602-MONOMER
- BRENDA:   2.2.1.2
- GO:   GO:0005737
- HAMAP:   MF_00492
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- PANTHER:   PTHR10683:SF3
- TIGRFAMs:   TIGR00874

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 35007; Mature: 34876

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQLDSLRNMTVVVADTGDIEAIKKYQPEDATTNPSLILSASALPQYASLIDEAIAYAK
CCCCHHCCCCCEEEEECCCCHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
SKSNCSKQQLIDAEDKLAVNIGLEILKIVPGRISTEVDARLSYDTQATIEKAKKLIALYN
CCCCCCHHHHCCCCCCEEEECCHHHHHHCCCCCCCCHHCEECCCHHHHHHHHHHHHHHHH
EAGISNDRILIKIASTWQGIRAAEELEKQGINCNLTLLFSEAQARACAEAGVYLISPFVG
HCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHH
RILDWYKANSDKKDYAPAEDPGVISVTKIYNYYKQHGYNTIVMGASFRNVGEITELAGCD
HHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCC
RLTIAPALLKELQENNAPLERKLSYTGEVKAKPQPLTEAEFYWQHNSDAMAVEKLADGIR
CCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
KFAADQEKLEAMLLTKF
HHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
TTQLDSLRNMTVVVADTGDIEAIKKYQPEDATTNPSLILSASALPQYASLIDEAIAYAK
CCCHHCCCCCEEEEECCCCHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
SKSNCSKQQLIDAEDKLAVNIGLEILKIVPGRISTEVDARLSYDTQATIEKAKKLIALYN
CCCCCCHHHHCCCCCCEEEECCHHHHHHCCCCCCCCHHCEECCCHHHHHHHHHHHHHHHH
EAGISNDRILIKIASTWQGIRAAEELEKQGINCNLTLLFSEAQARACAEAGVYLISPFVG
HCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHH
RILDWYKANSDKKDYAPAEDPGVISVTKIYNYYKQHGYNTIVMGASFRNVGEITELAGCD
HHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCC
RLTIAPALLKELQENNAPLERKLSYTGEVKAKPQPLTEAEFYWQHNSDAMAVEKLADGIR
CCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
KFAADQEKLEAMLLTKF
HHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100