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The map label for this gene is trkA [H]

Identifier: 15603428

GI number: 15603428

Start: 1770764

End: 1772140

Strand: Direct

Name: trkA [H]

Synonym: PM1563

Alternate gene names: 15603428

Gene position: 1770764-1772140 (Clockwise)

Preceding gene: 15603427

Following gene: 15603429

Centisome position: 78.44

GC content: 39.8

Gene sequence:

>1377_bases
ATGAAAATTATCATTCTTGGTGCAGGGCAGGTTGGTAAAACGCTTGCTGAGAATTTAGTCAGTGAAGATAACGACATTAC
ATTAGTCGATAATCAATCACTGCGATTAGAAAATTTACAAAGTAAGCATGACTTACGAGTCGTTAATGGTTCTGCTTCTT
CACCAAGAGTGTTACGTGAAGCTGGTGCGCAAGATGCGGATTTATTAGTGGCGGTTACGAGCTCTGATGAAATCAATATG
GTAGCGTGTCAAATTAGTTATACGCTTTTTAATACGCCCACTAAAATTGCGCGTATCCGTAATGCGGAATATTTACGTGA
AAAAGATAAATTATTCCAAACCAATGTGTTACCTATTGATCATATTATTTCACCGGAGAAATTAGTCACTGACGAAATTA
CACGTTTGATTGATTATCCGGGTGCGTTACAAGTGGCACATTTTGCGAATGGTCGCATTAGTTTGGTCGTTGTGAAAGCC
TATTATGGTGGTCCTTTAGTCGGCTATGCGATTTCTGCTTTGAAAGATCATATGCCACATATTGAATGTCGTATTGTGTC
TATTTTGCGTCAAGATAAAGTCATTCGTCCGCAAGGATCGACCATTATTGAGGCAGGTGATGAGATTACCTTTATCTGTG
AAACCATTCATATTAAAGCTGTGATGAGTGAATTGCAGCGTTTAGAGAAGCCGTATAAGCGCATTATGATCGCAGGCGGA
GGGAATGTCGGCATTGGTGTTGCGAAGAATTTAGAAGGAAAATGTTCCGTCAAATTAATTGAACGTAATGCAGAACGCGC
GACGGCATTGGCTGAAAAATTATCGAATACTTTGATTTTCTGTGGTGATGCTTCTGATCAGTCTTTTTTGTTAGAAGAGC
AAATCGAAAATGTGGATGTGTTTTTATCGCTTACCAGTGATGATGAAGCGAATATCATGTCAGCATTGTTAGCAAAACGA
CTTGGGGCGAAGAAAGCCTTGGTGTTAATTCAACGTATGGCATACATTAACTTGATCCAAGGTGGCACCATTGATATTGC
CGTTTCGCCACAACAGACGACGATTTCTGCGTTGTTAAGTCATGTTCGTAAAGGCGATACAGTGAATGTGGCCTCTTTAC
GACACGGGGTTGCTGAAGCGTTAGAGATTATTGTGCATGGCGAAGAAAGTTCGTCGCTTGTGATTGGACGTAAAATTTCT
GAATTGAAGTTACCACAAGGGGCGATTGTGGGAGCGATATTGCGTGGTAATGAGGTGATTATGGCGAAGAAAAATCTCGT
GATTGAAGATAATGATCATGTCATTGTGTATTTAAGTGATAAGAAATTTGTGTCTGATATCGAGAAACTTTTTCAGCCAA
GTGTATTCTTTATTTAA

Upstream 100 bases:

>100_bases
AAGTCACGGAGAATATTTGTAAACATGTGGACCAGTTGAAGAAACTATTGGATGTACAAGAGGTGGGTGTTAAACCTTTG
GTGATTGAGAGAACAGAATA

Downstream 100 bases:

>100_bases
AGTAGCGTAAATAAACTGTACAAAAAATCAAAAGTTCTTATAATGGCTAGGATTTTAGCTAACATTTTATTTAGGAGTTT
TTATGAGTTTTGTTAAAGAG

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKIIILGAGQVGKTLAENLVSEDNDITLVDNQSLRLENLQSKHDLRVVNGSASSPRVLREAGAQDADLLVAVTSSDEINM
VACQISYTLFNTPTKIARIRNAEYLREKDKLFQTNVLPIDHIISPEKLVTDEITRLIDYPGALQVAHFANGRISLVVVKA
YYGGPLVGYAISALKDHMPHIECRIVSILRQDKVIRPQGSTIIEAGDEITFICETIHIKAVMSELQRLEKPYKRIMIAGG
GNVGIGVAKNLEGKCSVKLIERNAERATALAEKLSNTLIFCGDASDQSFLLEEQIENVDVFLSLTSDDEANIMSALLAKR
LGAKKALVLIQRMAYINLIQGGTIDIAVSPQQTTISALLSHVRKGDTVNVASLRHGVAEALEIIVHGEESSSLVIGRKIS
ELKLPQGAIVGAILRGNEVIMAKKNLVIEDNDHVIVYLSDKKFVSDIEKLFQPSVFFI

Sequences:

>Translated_458_residues
MKIIILGAGQVGKTLAENLVSEDNDITLVDNQSLRLENLQSKHDLRVVNGSASSPRVLREAGAQDADLLVAVTSSDEINM
VACQISYTLFNTPTKIARIRNAEYLREKDKLFQTNVLPIDHIISPEKLVTDEITRLIDYPGALQVAHFANGRISLVVVKA
YYGGPLVGYAISALKDHMPHIECRIVSILRQDKVIRPQGSTIIEAGDEITFICETIHIKAVMSELQRLEKPYKRIMIAGG
GNVGIGVAKNLEGKCSVKLIERNAERATALAEKLSNTLIFCGDASDQSFLLEEQIENVDVFLSLTSDDEANIMSALLAKR
LGAKKALVLIQRMAYINLIQGGTIDIAVSPQQTTISALLSHVRKGDTVNVASLRHGVAEALEIIVHGEESSSLVIGRKIS
ELKLPQGAIVGAILRGNEVIMAKKNLVIEDNDHVIVYLSDKKFVSDIEKLFQPSVFFI
>Mature_458_residues
MKIIILGAGQVGKTLAENLVSEDNDITLVDNQSLRLENLQSKHDLRVVNGSASSPRVLREAGAQDADLLVAVTSSDEINM
VACQISYTLFNTPTKIARIRNAEYLREKDKLFQTNVLPIDHIISPEKLVTDEITRLIDYPGALQVAHFANGRISLVVVKA
YYGGPLVGYAISALKDHMPHIECRIVSILRQDKVIRPQGSTIIEAGDEITFICETIHIKAVMSELQRLEKPYKRIMIAGG
GNVGIGVAKNLEGKCSVKLIERNAERATALAEKLSNTLIFCGDASDQSFLLEEQIENVDVFLSLTSDDEANIMSALLAKR
LGAKKALVLIQRMAYINLIQGGTIDIAVSPQQTTISALLSHVRKGDTVNVASLRHGVAEALEIIVHGEESSSLVIGRKIS
ELKLPQGAIVGAILRGNEVIMAKKNLVIEDNDHVIVYLSDKKFVSDIEKLFQPSVFFI

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=67.0305676855895, Blast_Score=662, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50106; Mature: 50106

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGQVGKTLAENLVSEDNDITLVDNQSLRLENLQSKHDLRVVNGSASSPRVLRE
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCEEHHHCCCCCCEEEEECCCCCCHHHHH
AGAQDADLLVAVTSSDEINMVACQISYTLFNTPTKIARIRNAEYLREKDKLFQTNVLPID
CCCCCCEEEEEEECCCCEEEEEEEEEEEEECCCHHHHHHCCHHHHHHHHHHHHCCCCCHH
HIISPEKLVTDEITRLIDYPGALQVAHFANGRISLVVVKAYYGGPLVGYAISALKDHMPH
HCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHCCCC
IECRIVSILRQDKVIRPQGSTIIEAGDEITFICETIHIKAVMSELQRLEKPYKRIMIAGG
HHHHHHHHHHHCCEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHCHHHEEEEECC
GNVGIGVAKNLEGKCSVKLIERNAERATALAEKLSNTLIFCGDASDQSFLLEEQIENVDV
CCCCEEEECCCCCCEEEEEEECCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCEEE
FLSLTSDDEANIMSALLAKRLGAKKALVLIQRMAYINLIQGGTIDIAVSPQQTTISALLS
EEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCEEEEEECCCHHHHHHHHH
HVRKGDTVNVASLRHGVAEALEIIVHGEESSSLVIGRKISELKLPQGAIVGAILRGNEVI
HHHCCCCEEHHHHHHHHHHHEEEEEECCCCCCEEEECCHHHCCCCCCCEEEEEEECCEEE
MAKKNLVIEDNDHVIVYLSDKKFVSDIEKLFQPSVFFI
EEECCEEEECCCEEEEEECCCHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MKIIILGAGQVGKTLAENLVSEDNDITLVDNQSLRLENLQSKHDLRVVNGSASSPRVLRE
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCEEHHHCCCCCCEEEEECCCCCCHHHHH
AGAQDADLLVAVTSSDEINMVACQISYTLFNTPTKIARIRNAEYLREKDKLFQTNVLPID
CCCCCCEEEEEEECCCCEEEEEEEEEEEEECCCHHHHHHCCHHHHHHHHHHHHCCCCCHH
HIISPEKLVTDEITRLIDYPGALQVAHFANGRISLVVVKAYYGGPLVGYAISALKDHMPH
HCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHCCCC
IECRIVSILRQDKVIRPQGSTIIEAGDEITFICETIHIKAVMSELQRLEKPYKRIMIAGG
HHHHHHHHHHHCCEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHCHHHEEEEECC
GNVGIGVAKNLEGKCSVKLIERNAERATALAEKLSNTLIFCGDASDQSFLLEEQIENVDV
CCCCEEEECCCCCCEEEEEEECCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCEEE
FLSLTSDDEANIMSALLAKRLGAKKALVLIQRMAYINLIQGGTIDIAVSPQQTTISALLS
EEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCEEEEEECCCHHHHHHHHH
HVRKGDTVNVASLRHGVAEALEIIVHGEESSSLVIGRKISELKLPQGAIVGAILRGNEVI
HHHCCCCEEHHHHHHHHHHHEEEEEECCCCCCEEEECCHHHCCCCCCCEEEEEEECCEEE
MAKKNLVIEDNDHVIVYLSDKKFVSDIEKLFQPSVFFI
EEECCEEEECCCEEEEEECCCHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]