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The map label for this gene is sun

Identifier: 15603426

GI number: 15603426

Start: 1768603

End: 1769943

Strand: Direct

Name: sun

Synonym: PM1561

Alternate gene names: 15603426

Gene position: 1768603-1769943 (Clockwise)

Preceding gene: 15603425

Following gene: 15603427

Centisome position: 78.34

GC content: 41.39

Gene sequence:

>1341_bases
ATGCAGAAATTCGTAAAAAACGTGAAAAAGCAAACTGTACTTCTTTCAACAAGAGCCATTGCTGCACAAATCATTTTACA
AGTTCTGGATCAAGGTAAATCGCTATCAACCTTGATTCCAGACACGCAACATCAAGTTAAAACACAAGATTTACCTTTAT
TACAAGAAATTTGTTTTGGGGTATGTCGTGTATTACCTCGTTTAGAACTGATTATCAAGCAACTTGTGGACAAGCCATTA
AAAGGAAAAACACGCATTGTCCACTGCTTATTATTAGTTGGCTTATATCAGCTCCTTTATACTCGCATTCCTGCTCACGC
GGCAGTTGATGAAGTTGTCAATGCAACAACCGCGTTAAAAGCGGAACATTTCCGTGGTTTAGTGAATGGTGTGTTACGTC
GTTTTTTACGTGAACAAGAAACCTTATTGGTGAAAGTTGATAAACATTGGCACACATTGCACCCTGATTGGTTAGTTAAT
CGTTTGAAAGAAGCTTATCCAAATTGGCGTGAGATTGTTGAAGCGAATAATCACAAACCGCCGATGTGGTTACGTGTCAA
TCAGCAAAAAAATAGCACAGAAACGTACCGCACTTTATTGGCAGAACAAGGAATTGAGGCGGAAAAGGCAGATAATCCGT
GCGCATTACGTTTATTGCAACCTGTGGCAGTATCTCAATTGCCGGCATTTCATGAAGGCGCGGTGAGTGTACAAGATGTG
AATGCCCAATGGTCAGCCTTGTTATTGGCACCAGAAAATGGTGAACTCATTTTAGATGCCTGTGCGGCACCAGGCGGGAA
AACGACGCATATTTTAGAGCAAGCTCCACAAGCGCATGTGGTTGCTCTAGATGTTGAAGCTACTCGCCTTAAACGTGTGC
ATGAAAATTTAGCACGAATGCAACAGCAGGCAACGGTGATTTGTGGTGATGCCACACAGCCAGCACAATGGTTAAAGCAA
CTAAGTGAAAGTGCGGTACAATTTGACCGAATTTTATTGGATGCACCTTGTTCGGCAACCGGCGTGATTCGACGCCATCC
CGATATTAAGTGGTTAAGACAAGCATCGGATATTAGTGCATTAGTGGCACTACAAAAACAAATTTTACAAGCGCTCTGGA
CAGTATTAAAACCAAATGGAATTTTATTGTATGCAACTTGCTCGGTTTTACCAGAGGAAAATGCATTACAAATTGAACAA
TTTTTAACGAACAATGTAGATGCGAAATTAGAGCCACTCCCGTTTACGGCTGTAGAAGGGTCAGTTGGGTATCAGTTTCT
TCCAACTGAGAATGGGGGTGACGGTTTTTATTATGCTAAGTTAAGGAAGGTAGTTTCATGA

Upstream 100 bases:

>100_bases
TAAATTTGTTGCAATTACAACCCGCGGGGAAAAAGCCAATGGATGCGCGGGACTTGCTGAATGGGCGTGCAGAATGGTTT
CCTGTCGGTAAGGTTTTATG

Downstream 100 bases:

>100_bases
TGAACTTTAATAAAATGTCATTTTCAAAAATCGATGTTGTGATTCCTTGTTATAACGCGGAGAAAACGCTCATTCGTGCG
GTAAACTCCGTCTTAAATCA

Product: hypothetical protein

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MQKFVKNVKKQTVLLSTRAIAAQIILQVLDQGKSLSTLIPDTQHQVKTQDLPLLQEICFGVCRVLPRLELIIKQLVDKPL
KGKTRIVHCLLLVGLYQLLYTRIPAHAAVDEVVNATTALKAEHFRGLVNGVLRRFLREQETLLVKVDKHWHTLHPDWLVN
RLKEAYPNWREIVEANNHKPPMWLRVNQQKNSTETYRTLLAEQGIEAEKADNPCALRLLQPVAVSQLPAFHEGAVSVQDV
NAQWSALLLAPENGELILDACAAPGGKTTHILEQAPQAHVVALDVEATRLKRVHENLARMQQQATVICGDATQPAQWLKQ
LSESAVQFDRILLDAPCSATGVIRRHPDIKWLRQASDISALVALQKQILQALWTVLKPNGILLYATCSVLPEENALQIEQ
FLTNNVDAKLEPLPFTAVEGSVGYQFLPTENGGDGFYYAKLRKVVS

Sequences:

>Translated_446_residues
MQKFVKNVKKQTVLLSTRAIAAQIILQVLDQGKSLSTLIPDTQHQVKTQDLPLLQEICFGVCRVLPRLELIIKQLVDKPL
KGKTRIVHCLLLVGLYQLLYTRIPAHAAVDEVVNATTALKAEHFRGLVNGVLRRFLREQETLLVKVDKHWHTLHPDWLVN
RLKEAYPNWREIVEANNHKPPMWLRVNQQKNSTETYRTLLAEQGIEAEKADNPCALRLLQPVAVSQLPAFHEGAVSVQDV
NAQWSALLLAPENGELILDACAAPGGKTTHILEQAPQAHVVALDVEATRLKRVHENLARMQQQATVICGDATQPAQWLKQ
LSESAVQFDRILLDAPCSATGVIRRHPDIKWLRQASDISALVALQKQILQALWTVLKPNGILLYATCSVLPEENALQIEQ
FLTNNVDAKLEPLPFTAVEGSVGYQFLPTENGGDGFYYAKLRKVVS
>Mature_446_residues
MQKFVKNVKKQTVLLSTRAIAAQIILQVLDQGKSLSTLIPDTQHQVKTQDLPLLQEICFGVCRVLPRLELIIKQLVDKPL
KGKTRIVHCLLLVGLYQLLYTRIPAHAAVDEVVNATTALKAEHFRGLVNGVLRRFLREQETLLVKVDKHWHTLHPDWLVN
RLKEAYPNWREIVEANNHKPPMWLRVNQQKNSTETYRTLLAEQGIEAEKADNPCALRLLQPVAVSQLPAFHEGAVSVQDV
NAQWSALLLAPENGELILDACAAPGGKTTHILEQAPQAHVVALDVEATRLKRVHENLARMQQQATVICGDATQPAQWLKQ
LSESAVQFDRILLDAPCSATGVIRRHPDIKWLRQASDISALVALQKQILQALWTVLKPNGILLYATCSVLPEENALQIEQ
FLTNNVDAKLEPLPFTAVEGSVGYQFLPTENGGDGFYYAKLRKVVS

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family

Homologues:

Organism=Homo sapiens, GI76150625, Length=350, Percent_Identity=29.1428571428571, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI76150623, Length=350, Percent_Identity=29.1428571428571, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI32698918, Length=210, Percent_Identity=31.9047619047619, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI270288818, Length=259, Percent_Identity=28.957528957529, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI8922322, Length=259, Percent_Identity=28.957528957529, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI23199998, Length=254, Percent_Identity=29.1338582677165, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI11545785, Length=189, Percent_Identity=26.984126984127, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI270288816, Length=259, Percent_Identity=28.957528957529, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI301336155, Length=189, Percent_Identity=30.6878306878307, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI39995082, Length=189, Percent_Identity=30.6878306878307, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI2367212, Length=439, Percent_Identity=53.5307517084282, Blast_Score=446, Evalue=1e-126,
Organism=Escherichia coli, GI87081985, Length=325, Percent_Identity=27.3846153846154, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536757, Length=333, Percent_Identity=29.7297297297297, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI25143471, Length=186, Percent_Identity=35.4838709677419, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324268, Length=297, Percent_Identity=29.96632996633, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319447, Length=178, Percent_Identity=31.4606741573034, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI22024126, Length=243, Percent_Identity=32.5102880658436, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24668781, Length=221, Percent_Identity=31.6742081447964, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356513, Length=221, Percent_Identity=31.6742081447964, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355201, Length=195, Percent_Identity=30.2564102564103, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920494, Length=160, Percent_Identity=30, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMB_PASMU (Q9CKP7)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246500.1
- ProteinModelPortal:   Q9CKP7
- SMR:   Q9CKP7
- GeneID:   1244908
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1561
- NMPDR:   fig|272843.1.peg.1562
- HOGENOM:   HBG726909
- OMA:   ANNAHPP
- ProtClustDB:   PRK10901
- BioCyc:   PMUL272843:PM1561-MONOMER
- GO:   GO:0005737
- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573
- Gene3D:   G3DSA:1.10.940.10
- TIGRFAMs:   TIGR00563

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB; SSF48013 NusB_RsmB_TIM44

EC number: =2.1.1.176

Molecular weight: Translated: 49886; Mature: 49886

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: ACT_SITE 387-387 BINDING 284-284 BINDING 310-310 BINDING 334-334

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKFVKNVKKQTVLLSTRAIAAQIILQVLDQGKSLSTLIPDTQHQVKTQDLPLLQEICFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCCHHHHHHHHH
VCRVLPRLELIIKQLVDKPLKGKTRIVHCLLLVGLYQLLYTRIPAHAAVDEVVNATTALK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEHFRGLVNGVLRRFLREQETLLVKVDKHWHTLHPDWLVNRLKEAYPNWREIVEANNHKP
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCC
PMWLRVNQQKNSTETYRTLLAEQGIEAEKADNPCALRLLQPVAVSQLPAFHEGAVSVQDV
CEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEC
NAQWSALLLAPENGELILDACAAPGGKTTHILEQAPQAHVVALDVEATRLKRVHENLARM
CCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHH
QQQATVICGDATQPAQWLKQLSESAVQFDRILLDAPCSATGVIRRHPDIKWLRQASDISA
HHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHH
LVALQKQILQALWTVLKPNGILLYATCSVLPEENALQIEQFLTNNVDAKLEPLPFTAVEG
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECC
SVGYQFLPTENGGDGFYYAKLRKVVS
CCCEEEECCCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MQKFVKNVKKQTVLLSTRAIAAQIILQVLDQGKSLSTLIPDTQHQVKTQDLPLLQEICFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCCHHHHHHHHH
VCRVLPRLELIIKQLVDKPLKGKTRIVHCLLLVGLYQLLYTRIPAHAAVDEVVNATTALK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEHFRGLVNGVLRRFLREQETLLVKVDKHWHTLHPDWLVNRLKEAYPNWREIVEANNHKP
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCC
PMWLRVNQQKNSTETYRTLLAEQGIEAEKADNPCALRLLQPVAVSQLPAFHEGAVSVQDV
CEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEC
NAQWSALLLAPENGELILDACAAPGGKTTHILEQAPQAHVVALDVEATRLKRVHENLARM
CCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHH
QQQATVICGDATQPAQWLKQLSESAVQFDRILLDAPCSATGVIRRHPDIKWLRQASDISA
HHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHH
LVALQKQILQALWTVLKPNGILLYATCSVLPEENALQIEQFLTNNVDAKLEPLPFTAVEG
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECC
SVGYQFLPTENGGDGFYYAKLRKVVS
CCCEEEECCCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100